Is SGMO or CDXS more profitable?

Codexis has a net margin of -40.97% compared to Sangamo Therapeutics' net margin of -310.81%. Codexis' return on equity of -68.09% beat Sangamo Therapeutics' return on equity. Company Net Margins Return on Equity Return on Assets Sangamo Therapeutics -310.81% -2,662.06% -132.12% Codexis -40.97% -68.09% -23.72%

Is SGMO or AGEN more profitable?

Agenus has a net margin of 50.49% compared to Sangamo Therapeutics' net margin of -310.81%. Agenus' return on equity of -31.66% beat Sangamo Therapeutics' return on equity. Company Net Margins Return on Equity Return on Assets Sangamo Therapeutics -310.81% -2,662.06% -132.12% Agenus 50.49% -31.66% 42.71%

Do analysts rate DOMH or SGMO?

Sangamo Therapeutics has a consensus target price of $5.50, indicating a potential upside of 3,135.29%. Given Sangamo Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Sangamo Therapeutics is more favorable than Dominari. Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Dominari 1 Sell rating(s) 0 Hold rating(s) 0 Buy rating(s) 0 Strong Buy rating(s) 1.00 Sangamo Therapeutics 2 Sell rating(s) 1 Hold rating(s) 1 Buy rating(s) 0 Strong Buy rating(s) 1.75

Is DOMH or SGMO more profitable?

Dominari has a net margin of -31.37% compared to Sangamo Therapeutics' net margin of -310.81%. Dominari's return on equity of -206.20% beat Sangamo Therapeutics' return on equity. Company Net Margins Return on Equity Return on Assets Dominari -31.37% -206.20% -155.26% Sangamo Therapeutics -310.81% -2,662.06% -132.12%

Sangamo Therapeutics (SGMO) Competitors

$0.17 +0.01 (+3.03%)

As of 03:58 PM Eastern

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SGMO vs. SABS, CDXS, AGEN, FBIO, and DOMH

Should you buy Sangamo Therapeutics stock or one of its competitors? MarketBeat compares Sangamo Therapeutics with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Sangamo Therapeutics include SAB Biotherapeutics (SABS), Codexis (CDXS), Agenus (AGEN), Fortress Biotech (FBIO), and Dominari (DOMH). These companies are all part of the "biotechnology" industry.

How does Sangamo Therapeutics compare to SAB Biotherapeutics?

Sangamo Therapeutics (NASDAQ:SGMO) and SAB Biotherapeutics (NASDAQ:SABS) are both small-cap medical companies, but which is the superior business? We will contrast the two businesses based on the strength of their risk, media sentiment, valuation, institutional ownership, analyst recommendations, profitability, dividends and earnings.

Sangamo Therapeutics has a beta of 1.3, suggesting that its share price is 30% more volatile than the broader market. Comparatively, SAB Biotherapeutics has a beta of 0.54, suggesting that its share price is 46% less volatile than the broader market.

56.9% of Sangamo Therapeutics shares are held by institutional investors. Comparatively, 7.8% of SAB Biotherapeutics shares are held by institutional investors. 4.1% of Sangamo Therapeutics shares are held by company insiders. Comparatively, 7.4% of SAB Biotherapeutics shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term.

In the previous week, SAB Biotherapeutics had 2 more articles in the media than Sangamo Therapeutics. MarketBeat recorded 2 mentions for SAB Biotherapeutics and 0 mentions for Sangamo Therapeutics. SAB Biotherapeutics' average media sentiment score of 0.96 beat Sangamo Therapeutics' score of 0.00 indicating that SAB Biotherapeutics is being referred to more favorably in the news media.

Company	Overall Sentiment
Sangamo Therapeutics	Neutral
SAB Biotherapeutics	Positive

SAB Biotherapeutics has a net margin of 0.00% compared to Sangamo Therapeutics' net margin of -310.81%. SAB Biotherapeutics' return on equity of -0.29% beat Sangamo Therapeutics' return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Sangamo Therapeutics	-310.81%	-2,662.06%	-132.12%
SAB Biotherapeutics	N/A	-0.29%	-0.25%

Sangamo Therapeutics presently has a consensus target price of $5.50, suggesting a potential upside of 3,135.29%. SAB Biotherapeutics has a consensus target price of $11.63, suggesting a potential upside of 217.62%. Given Sangamo Therapeutics' higher probable upside, equities research analysts clearly believe Sangamo Therapeutics is more favorable than SAB Biotherapeutics.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Sangamo Therapeutics	2 Sell rating(s)	1 Hold rating(s)	1 Buy rating(s)	0 Strong Buy rating(s)	1.75
SAB Biotherapeutics	1 Sell rating(s)	1 Hold rating(s)	8 Buy rating(s)	0 Strong Buy rating(s)	2.70

SAB Biotherapeutics has lower revenue, but higher earnings than Sangamo Therapeutics. SAB Biotherapeutics is trading at a lower price-to-earnings ratio than Sangamo Therapeutics, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Sangamo Therapeutics	$39.55M	1.78	-$122.93M	-$0.38	N/A
SAB Biotherapeutics	$1.32M	212.00	$13.27M	-$2.11	N/A

Summary

SAB Biotherapeutics beats Sangamo Therapeutics on 10 of the 16 factors compared between the two stocks.

How does Sangamo Therapeutics compare to Codexis?

Sangamo Therapeutics (NASDAQ:SGMO) and Codexis (NASDAQ:CDXS) are both small-cap medical companies, but which is the better investment? We will contrast the two companies based on the strength of their institutional ownership, risk, media sentiment, analyst recommendations, profitability, dividends, valuation and earnings.

Codexis has a net margin of -40.97% compared to Sangamo Therapeutics' net margin of -310.81%. Codexis' return on equity of -68.09% beat Sangamo Therapeutics' return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Sangamo Therapeutics	-310.81%	-2,662.06%	-132.12%
Codexis	-40.97%	-68.09%	-23.72%

56.9% of Sangamo Therapeutics shares are held by institutional investors. Comparatively, 78.5% of Codexis shares are held by institutional investors. 4.1% of Sangamo Therapeutics shares are held by company insiders. Comparatively, 3.5% of Codexis shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

Sangamo Therapeutics has a beta of 1.3, indicating that its stock price is 30% more volatile than the broader market. Comparatively, Codexis has a beta of 2.48, indicating that its stock price is 148% more volatile than the broader market.

In the previous week, Codexis had 1 more articles in the media than Sangamo Therapeutics. MarketBeat recorded 1 mentions for Codexis and 0 mentions for Sangamo Therapeutics. Codexis' average media sentiment score of 0.43 beat Sangamo Therapeutics' score of 0.00 indicating that Codexis is being referred to more favorably in the news media.

Company	Overall Sentiment
Sangamo Therapeutics	Neutral
Codexis	Neutral

Sangamo Therapeutics currently has a consensus price target of $5.50, indicating a potential upside of 3,135.29%. Codexis has a consensus price target of $5.00, indicating a potential upside of 101.61%. Given Sangamo Therapeutics' higher possible upside, research analysts plainly believe Sangamo Therapeutics is more favorable than Codexis.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Sangamo Therapeutics	2 Sell rating(s)	1 Hold rating(s)	1 Buy rating(s)	0 Strong Buy rating(s)	1.75
Codexis	1 Sell rating(s)	0 Hold rating(s)	1 Buy rating(s)	0 Strong Buy rating(s)	2.00

Codexis has higher revenue and earnings than Sangamo Therapeutics. Codexis is trading at a lower price-to-earnings ratio than Sangamo Therapeutics, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Sangamo Therapeutics	$39.55M	1.78	-$122.93M	-$0.38	N/A
Codexis	$70.39M	3.20	-$43.97M	-$0.37	N/A

Summary

Codexis beats Sangamo Therapeutics on 12 of the 15 factors compared between the two stocks.

How does Sangamo Therapeutics compare to Agenus?

Sangamo Therapeutics (NASDAQ:SGMO) and Agenus (NASDAQ:AGEN) are both small-cap medical companies, but which is the superior business? We will compare the two businesses based on the strength of their profitability, institutional ownership, earnings, media sentiment, analyst recommendations, risk, dividends and valuation.

In the previous week, Agenus had 2 more articles in the media than Sangamo Therapeutics. MarketBeat recorded 2 mentions for Agenus and 0 mentions for Sangamo Therapeutics. Sangamo Therapeutics' average media sentiment score of 0.00 beat Agenus' score of -0.15 indicating that Sangamo Therapeutics is being referred to more favorably in the media.

Company	Overall Sentiment
Sangamo Therapeutics	Neutral
Agenus	Neutral

Sangamo Therapeutics presently has a consensus target price of $5.50, indicating a potential upside of 3,135.29%. Agenus has a consensus target price of $23.00, indicating a potential upside of 671.81%. Given Sangamo Therapeutics' higher probable upside, research analysts plainly believe Sangamo Therapeutics is more favorable than Agenus.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Sangamo Therapeutics	2 Sell rating(s)	1 Hold rating(s)	1 Buy rating(s)	0 Strong Buy rating(s)	1.75
Agenus	1 Sell rating(s)	1 Hold rating(s)	1 Buy rating(s)	0 Strong Buy rating(s)	2.00

Sangamo Therapeutics has a beta of 1.3, suggesting that its share price is 30% more volatile than the broader market. Comparatively, Agenus has a beta of 1.57, suggesting that its share price is 57% more volatile than the broader market.

56.9% of Sangamo Therapeutics shares are owned by institutional investors. Comparatively, 61.5% of Agenus shares are owned by institutional investors. 4.1% of Sangamo Therapeutics shares are owned by insiders. Comparatively, 6.5% of Agenus shares are owned by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company is poised for long-term growth.

Agenus has a net margin of 50.49% compared to Sangamo Therapeutics' net margin of -310.81%. Agenus' return on equity of -31.66% beat Sangamo Therapeutics' return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Sangamo Therapeutics	-310.81%	-2,662.06%	-132.12%
Agenus	50.49%	-31.66%	42.71%

Agenus has higher revenue and earnings than Sangamo Therapeutics. Sangamo Therapeutics is trading at a lower price-to-earnings ratio than Agenus, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Sangamo Therapeutics	$39.55M	1.78	-$122.93M	-$0.38	N/A
Agenus	$114.20M	1.09	$120K	$1.59	1.87

Summary

Agenus beats Sangamo Therapeutics on 12 of the 15 factors compared between the two stocks.

How does Sangamo Therapeutics compare to Fortress Biotech?

Sangamo Therapeutics (NASDAQ:SGMO) and Fortress Biotech (NASDAQ:FBIO) are both small-cap medical companies, but which is the better stock? We will contrast the two businesses based on the strength of their earnings, risk, media sentiment, valuation, institutional ownership, profitability, analyst recommendations and dividends.

Sangamo Therapeutics presently has a consensus target price of $5.50, suggesting a potential upside of 3,135.29%. Fortress Biotech has a consensus target price of $17.00, suggesting a potential upside of 480.20%. Given Sangamo Therapeutics' higher possible upside, equities analysts clearly believe Sangamo Therapeutics is more favorable than Fortress Biotech.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Sangamo Therapeutics	2 Sell rating(s)	1 Hold rating(s)	1 Buy rating(s)	0 Strong Buy rating(s)	1.75
Fortress Biotech	1 Sell rating(s)	1 Hold rating(s)	2 Buy rating(s)	0 Strong Buy rating(s)	2.25

Fortress Biotech has higher revenue and earnings than Sangamo Therapeutics. Sangamo Therapeutics is trading at a lower price-to-earnings ratio than Fortress Biotech, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Sangamo Therapeutics	$39.55M	1.78	-$122.93M	-$0.38	N/A
Fortress Biotech	$66.16M	1.47	$6.82M	$3.17	0.92

In the previous week, Fortress Biotech's average media sentiment score of 1.87 beat Sangamo Therapeutics' score of 0.00 indicating that Fortress Biotech is being referred to more favorably in the news media.

Company	Overall Sentiment
Sangamo Therapeutics	Neutral
Fortress Biotech	Very Positive

Sangamo Therapeutics has a beta of 1.3, indicating that its stock price is 30% more volatile than the broader market. Comparatively, Fortress Biotech has a beta of 1.22, indicating that its stock price is 22% more volatile than the broader market.

56.9% of Sangamo Therapeutics shares are held by institutional investors. Comparatively, 96.5% of Fortress Biotech shares are held by institutional investors. 4.1% of Sangamo Therapeutics shares are held by insiders. Comparatively, 28.5% of Fortress Biotech shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

Fortress Biotech has a net margin of 193.12% compared to Sangamo Therapeutics' net margin of -310.81%. Fortress Biotech's return on equity of 109.66% beat Sangamo Therapeutics' return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Sangamo Therapeutics	-310.81%	-2,662.06%	-132.12%
Fortress Biotech	193.12%	109.66%	45.56%

Summary

Fortress Biotech beats Sangamo Therapeutics on 12 of the 15 factors compared between the two stocks.

How does Sangamo Therapeutics compare to Dominari?

Dominari (NASDAQ:DOMH) and Sangamo Therapeutics (NASDAQ:SGMO) are both small-cap medical companies, but which is the superior investment? We will compare the two businesses based on the strength of their media sentiment, institutional ownership, valuation, risk, analyst recommendations, earnings, dividends and profitability.

Dominari has a beta of 0.8, meaning that its stock price is 20% less volatile than the broader market. Comparatively, Sangamo Therapeutics has a beta of 1.3, meaning that its stock price is 30% more volatile than the broader market.

Dominari has higher revenue and earnings than Sangamo Therapeutics. Dominari is trading at a lower price-to-earnings ratio than Sangamo Therapeutics, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Dominari	$123.10M	0.59	-$22.43M	-$4.03	N/A
Sangamo Therapeutics	$39.55M	1.78	-$122.93M	-$0.38	N/A

Dominari has a net margin of -31.37% compared to Sangamo Therapeutics' net margin of -310.81%. Dominari's return on equity of -206.20% beat Sangamo Therapeutics' return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Dominari	-31.37%	-206.20%	-155.26%
Sangamo Therapeutics	-310.81%	-2,662.06%	-132.12%

Sangamo Therapeutics has a consensus target price of $5.50, indicating a potential upside of 3,135.29%. Given Sangamo Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Sangamo Therapeutics is more favorable than Dominari.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Dominari	1 Sell rating(s)	0 Hold rating(s)	0 Buy rating(s)	0 Strong Buy rating(s)	1.00
Sangamo Therapeutics	2 Sell rating(s)	1 Hold rating(s)	1 Buy rating(s)	0 Strong Buy rating(s)	1.75

42.5% of Dominari shares are held by institutional investors. Comparatively, 56.9% of Sangamo Therapeutics shares are held by institutional investors. 55.3% of Dominari shares are held by insiders. Comparatively, 4.1% of Sangamo Therapeutics shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company will outperform the market over the long term.

In the previous week, Dominari had 2 more articles in the media than Sangamo Therapeutics. MarketBeat recorded 2 mentions for Dominari and 0 mentions for Sangamo Therapeutics. Dominari's average media sentiment score of 0.72 beat Sangamo Therapeutics' score of 0.00 indicating that Dominari is being referred to more favorably in the media.

Company	Overall Sentiment
Dominari	Positive
Sangamo Therapeutics	Neutral

Summary

Sangamo Therapeutics beats Dominari on 9 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding SGMO and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.

Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.

SGMO vs. The Competition

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Metric	Sangamo Therapeutics	MED Industry	Medical Sector	NASDAQ Exchange
Market Cap	$70.43M	$3.37B	$6.46B	$12.21B
Dividend Yield	N/A	2.25%	2.66%	5.66%
P/E Ratio	-0.39	19.66	23.92	24.34
Price / Sales	1.78	307.95	518.20	135.97
Price / Cash	N/A	53.61	27.48	37.92
Price / Book	-4.25	8.03	10.50	6.73
Net Income	-$122.93M	$23.89M	$3.56B	$337.21M
7 Day Performance	13.26%	1.04%	0.24%	1.86%
1 Month Performance	25.93%	-0.23%	1.52%	3.74%
1 Year Performance	-66.00%	43.80%	24.28%	28.38%

Sangamo Therapeutics Competitors List

Export

Company	MarketRank	Share Price	Analysts' Price Target	1Y Price Performance	Market Cap	Revenue	P/E Ratio	Employee Count	Indicator(s)
SGMO Sangamo Therapeutics	1.1591 of 5 stars	$0.17 +3.0%	$5.50 +3,135.3%	-66.4%	$70.43M	$39.55M	N/A	480	Gap Up
SABS SAB Biotherapeutics	3.876 of 5 stars	$3.40 +0.6%	$11.00 +223.5%	+128.1%	$258.45M	$1.32M	N/A	140	Analyst Forecast
CDXS Codexis	2.0475 of 5 stars	$2.61 +2.0%	$5.00 +91.6%	+11.7%	$232.70M	$70.39M	N/A	250	Gap Up
AGEN Agenus	2.1881 of 5 stars	$3.14 -2.8%	$23.00 +632.5%	-30.9%	$134.51M	$114.20M	1.97	440	Gap Up
FBIO Fortress Biotech	4.0004 of 5 stars	$2.85 +7.5%	$17.00 +496.5%	+54.6%	$88.03M	$63.26M	0.90	170	Positive News High Trading Volume

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This page (NASDAQ:SGMO) was last updated on 6/16/2026 by MarketBeat.com Staff.

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Sangamo Therapeutics (SGMO) Competitors

SGMO vs. SABS, CDXS, AGEN, FBIO, and DOMH

How does Sangamo Therapeutics compare to SAB Biotherapeutics?

Summary

How does Sangamo Therapeutics compare to Codexis?

Summary

How does Sangamo Therapeutics compare to Agenus?

Summary

How does Sangamo Therapeutics compare to Fortress Biotech?

Summary

How does Sangamo Therapeutics compare to Dominari?

Summary

New MarketBeat Followers Over Time

Media Sentiment Over Time

SGMO vs. The Competition

Sangamo Therapeutics Competitors List

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Sangamo Therapeutics (SGMO) Competitors

SGMO vs. SABS, CDXS, AGEN, FBIO, and DOMH

How does Sangamo Therapeutics compare to SAB Biotherapeutics?

Which has more risk & volatility, SGMO or SABS?

Do insiders & institutionals believe in SGMO or SABS?

Does the media refer more to SGMO or SABS?

Is SGMO or SABS more profitable?

Do analysts prefer SGMO or SABS?

Which has better earnings & valuation, SGMO or SABS?

Summary

How does Sangamo Therapeutics compare to Codexis?

Is SGMO or CDXS more profitable?

Do institutionals & insiders have more ownership in SGMO or CDXS?

Which has more volatility and risk, SGMO or CDXS?

Does the media refer more to SGMO or CDXS?

Do analysts rate SGMO or CDXS?

Which has better earnings and valuation, SGMO or CDXS?

Summary

How does Sangamo Therapeutics compare to Agenus?

Does the media favor SGMO or AGEN?

Do analysts prefer SGMO or AGEN?

Which has more risk and volatility, SGMO or AGEN?

Do institutionals and insiders believe in SGMO or AGEN?

Is SGMO or AGEN more profitable?

Which has better valuation & earnings, SGMO or AGEN?

Summary

How does Sangamo Therapeutics compare to Fortress Biotech?

Do analysts recommend SGMO or FBIO?

Which has stronger valuation & earnings, SGMO or FBIO?

Does the media favor SGMO or FBIO?

Which has more volatility & risk, SGMO or FBIO?

Do institutionals & insiders hold more shares of SGMO or FBIO?

Is SGMO or FBIO more profitable?

Summary

How does Sangamo Therapeutics compare to Dominari?

Which has more volatility & risk, DOMH or SGMO?

Which has preferable valuation and earnings, DOMH or SGMO?

Is DOMH or SGMO more profitable?

Do analysts rate DOMH or SGMO?

Do institutionals and insiders have more ownership in DOMH or SGMO?

Does the media refer more to DOMH or SGMO?

Summary

New MarketBeat Followers Over Time

Media Sentiment Over Time

SGMO vs. The Competition

Sangamo Therapeutics Competitors List

Related Companies and Tools

MarketBeat All Access Features

Best-in-Class Portfolio Monitoring

Stock Ideas and Recommendations

Advanced Stock Screeners and Research Tools