| 8/7/2026 | BlackRock Inc. | 994,654 | $975K | 0.0% | N/A | 1.522% | |
| 8/6/2026 | GSA Capital Partners LLP | 548,087 | $537K | 0.0% | N/A | 0.839% | |
| 5/19/2026 | Bank of America Corp DE | 57,529 | $58K | 0.0% | +48.7% | 0.088% | |
| 5/14/2026 | Renaissance Technologies LLC | 1,364,783 | $1.38M | 0.0% | +19.6% | 2.088% | |
| 5/14/2026 | Public Employees Retirement System of Ohio | 27,700 | $28K | 0.0% | N/A | 0.049% | |
| 5/7/2026 | Dimensional Fund Advisors LP | 65,335 | $66K | 0.0% | -12.3% | 0.115% | |
| 4/30/2026 | Kestra Advisory Services LLC | 62,525 | $63K | 0.0% | N/A | 0.110% | |
| 2/18/2026 | XTX Topco Ltd | 219,001 | $219K | 0.0% | +1,142.5% | 0.386% | |
| 2/18/2026 | Tang Capital Management LLC | 46,131 | $46K | 0.0% | -92.3% | 0.081% | |
| 2/18/2026 | Millennium Management LLC | 403,618 | $404K | 0.0% | -13.4% | 0.711% | |
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| 2/18/2026 | Bridgeway Capital Management LLC | 115,400 | $115K | 0.0% | -17.8% | 0.203% | |
| 2/16/2026 | Panagora Asset Management Inc. | 25,256 | $25K | 0.0% | N/A | 0.045% | |
| 2/13/2026 | Marshall Wace LLP | 339,240 | $339K | 0.0% | +627.5% | 0.598% | |
| 2/13/2026 | Stifel Financial Corp | 72,400 | $72K | 0.0% | -25.7% | 0.128% | |
| 2/12/2026 | Jane Street Group LLC | 388,284 | $388K | 0.0% | +377.5% | 0.684% | |
| 2/12/2026 | HRT Financial LP | 26,581 | $26K | 0.0% | N/A | 0.047% | |
| 2/12/2026 | Renaissance Technologies LLC | 1,141,069 | $1.14M | 0.0% | +37.5% | 2.011% | |
| 2/12/2026 | Dimensional Fund Advisors LP | 74,467 | $75K | 0.0% | -14.7% | 0.131% | |
| 2/10/2026 | Goldman Sachs Group Inc. | 86,903 | $87K | 0.0% | -33.7% | 0.153% | |
| 1/16/2026 | Aberdeen Group plc | 1,785,241 | $1.79M | 0.0% | +31.8% | 3.146% | |
| 1/1/2026 | JPMorgan Chase & Co. | 237,750 | $433K | 0.0% | -17.4% | 0.419% | |
| 11/17/2025 | Voleon Capital Management LP | 47,879 | $87K | 0.0% | N/A | 0.084% | |
| 11/17/2025 | Susquehanna International Group LLP | 79,760 | $145K | 0.0% | -44.8% | 0.141% | |
| 11/17/2025 | Qube Research & Technologies Ltd | 27,675 | $50K | 0.0% | -59.5% | 0.049% | |
| 11/17/2025 | Millennium Management LLC | 466,086 | $848K | 0.0% | -26.0% | 0.821% | |
| 11/17/2025 | Citadel Advisors LLC | 390,747 | $711K | 0.0% | +78.4% | 0.689% | |
| 11/14/2025 | Virtu Financial LLC | 60,480 | $110K | 0.0% | +431.1% | 0.107% | |
| 11/14/2025 | Two Sigma Investments LP | 419,404 | $763K | 0.0% | +14.9% | 0.739% | |
| 11/14/2025 | Bridgeway Capital Management LLC | 140,400 | $256K | 0.0% | -8.7% | 0.247% | |
| 11/12/2025 | Propel Bio Management LLC | 1,932,304 | $3.52M | 3.5% | -7.4% | 3.405% | |
| 11/12/2025 | Dimensional Fund Advisors LP | 87,316 | $159K | 0.0% | -32.8% | 0.154% | |
| 11/7/2025 | Vanguard Group Inc. | 2,317,916 | $4.22M | 0.0% | +7.8% | 4.084% | |
| 11/7/2025 | JPMorgan Chase & Co. | 237,750 | $433K | 0.0% | -17.4% | 0.419% | |
| 11/7/2025 | Aberdeen Group plc | 1,354,820 | $2.47M | 0.0% | +52.0% | 2.387% | |
| 10/20/2025 | Simplify Asset Management Inc. | 904,972 | $1.65M | 0.0% | -13.6% | 1.595% | |
| 8/15/2025 | Militia Capital Partners LP | 94,300 | $137K | 0.1% | N/A | 0.167% | |
| 8/15/2025 | BNP Paribas Financial Markets | 23,697 | $34K | 0.0% | -54.3% | 0.042% | |
| 8/15/2025 | Boothbay Fund Management LLC | 24,363 | $35K | 0.0% | +50.0% | 0.043% | |
| 8/15/2025 | Bridgeway Capital Management LLC | 153,700 | $223K | 0.0% | +35.7% | 0.272% | |
| 8/15/2025 | BVF Inc. IL | 5,226,074 | $7.58M | 0.3% | +6.9% | 9.235% | |
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| 8/15/2025 | Bank of America Corp DE | 217,967 | $316K | 0.0% | +28.0% | 0.385% | |
| 8/14/2025 | Jane Street Group LLC | 213,396 | $309K | 0.0% | N/A | 0.377% | |
| 8/14/2025 | Qube Research & Technologies Ltd | 68,286 | $99K | 0.0% | N/A | 0.121% | |
| 8/13/2025 | Marshall Wace LLP | 53,678 | $78K | 0.0% | N/A | 0.095% | |
| 8/13/2025 | Quadrature Capital Ltd | 22,500 | $33K | 0.0% | N/A | 0.040% | |
| 8/12/2025 | JPMorgan Chase & Co. | 287,743 | $417K | 0.0% | +8.5% | 0.508% | |
| 8/12/2025 | Catalyst Funds Management Pty Ltd | 18,000 | $26K | 0.0% | N/A | 0.032% | |
| 8/8/2025 | Letko Brosseau & Associates Inc. | 95,875 | $139K | 0.0% | +24.4% | 0.169% | |
| 8/8/2025 | Geode Capital Management LLC | 566,371 | $822K | 0.0% | -44.2% | 1.001% | |
| 8/1/2025 | Y Intercept Hong Kong Ltd | 76,660 | $111K | 0.0% | N/A | 0.135% | |
| 7/25/2025 | Vanguard Personalized Indexing Management LLC | 19,892 | $29K | 0.0% | N/A | 0.035% | |
| 6/27/2025 | Goldman Sachs Group Inc. | 170,349 | $235K | 0.0% | +6.0% | 0.301% | |
| 5/16/2025 | Goldman Sachs Group Inc. | 170,349 | $235K | 0.0% | +6.0% | 0.301% | |
| 5/16/2025 | EcoR1 Capital LLC | 662,833 | $915K | 0.1% | -86.7% | 1.171% | |
| 5/16/2025 | Checkpoint Capital L.P. | 2,017,650 | $2.78M | 1.5% | +14.9% | 3.565% | |
| 5/16/2025 | BVF Inc. IL | 4,889,474 | $6.75M | 0.3% | +63.6% | 8.640% | |
| 5/15/2025 | Troluce Capital Advisors LLC | 83,758 | $116K | 0.0% | +58.3% | 0.148% | |
| 5/15/2025 | Cubist Systematic Strategies LLC | 20,840 | $29K | 0.0% | -67.0% | 0.037% | |
| 5/14/2025 | Hsbc Holdings PLC | 35,042 | $49K | 0.0% | N/A | 0.062% | |
| 5/13/2025 | Tocqueville Asset Management L.P. | 27,000 | $37K | 0.0% | -89.7% | 0.048% | |
| 5/13/2025 | Aberdeen Group plc | 891,448 | $1.23M | 0.0% | +0.9% | 1.575% | |
| 5/12/2025 | Nuveen LLC | 69,962 | $97K | 0.0% | N/A | 0.124% | |
| 5/9/2025 | Deutsche Bank AG | 52,559 | $73K | 0.0% | +149.4% | 0.093% | |
| 5/8/2025 | Letko Brosseau & Associates Inc. | 77,100 | $106K | 0.0% | +113.0% | 0.136% | |
| 3/24/2025 | Wellington Management Group LLP | 132,895 | $404K | 0.0% | +5.2% | 0.235% | |
| 2/25/2025 | Heck Capital Advisors LLC | 20,120 | $61K | 0.0% | N/A | 0.038% | |
| 2/17/2025 | Woodline Partners LP | 115,866 | $352K | 0.0% | +6.7% | 0.217% | |
| 2/17/2025 | Squarepoint Ops LLC | 19,461 | $59K | 0.0% | N/A | 0.036% | |
| 2/17/2025 | Tang Capital Management LLC | 117,847 | $358K | 0.0% | N/A | 0.221% | |
| 2/17/2025 | Shay Capital LLC | 21,363 | $65K | 0.0% | N/A | 0.040% | |
| 2/17/2025 | ProShare Advisors LLC | 13,140 | $40K | 0.0% | N/A | 0.025% | |
| 2/17/2025 | Letko Brosseau & Associates Inc. | 36,200 | $110K | 0.0% | +74.9% | 0.068% | |
| 2/17/2025 | Jacobs Levy Equity Management Inc. | 18,951 | $58K | 0.0% | -81.7% | 0.036% | |
| 2/17/2025 | Cubist Systematic Strategies LLC | 63,095 | $192K | 0.0% | +96.3% | 0.118% | |
| 2/17/2025 | Bridgeway Capital Management LLC | 105,900 | $322K | 0.0% | +176.5% | 0.198% | |
| 2/17/2025 | Bank of America Corp DE | 150,114 | $456K | 0.0% | +54.4% | 0.281% | |
| 2/17/2025 | BNP Paribas Financial Markets | 65,139 | $198K | 0.0% | N/A | 0.122% | |
| 2/14/2025 | Lynx1 Capital Management LP | 5,357,347 | $16.29M | 6.1% | +2.5% | 10.038% | |
| 2/14/2025 | Dauntless Investment Group LLC | 110,345 | $335K | 0.4% | N/A | 0.207% | |
| 2/14/2025 | Adage Capital Partners GP L.L.C. | 3,500,000 | $10.64M | 0.0% | -20.5% | 6.558% | |
| 2/14/2025 | Stifel Financial Corp | 109,700 | $333K | 0.0% | +10.7% | 0.206% | |
| 2/14/2025 | Dimensional Fund Advisors LP | 280,028 | $851K | 0.0% | +108.5% | 0.525% | |
| 2/13/2025 | Marshall Wace LLP | 43,969 | $134K | 0.0% | -73.4% | 0.082% | |
| 2/13/2025 | Barclays PLC | 67,508 | $206K | 0.0% | +16.3% | 0.126% | |
| 2/13/2025 | Renaissance Technologies LLC | 10,600 | $32K | 0.0% | -85.7% | 0.020% | |
| 2/13/2025 | Wells Fargo & Company MN | 19,540 | $59K | 0.0% | +41.1% | 0.037% | |
| 2/12/2025 | Geode Capital Management LLC | 963,257 | $2.93M | 0.0% | -1.0% | 1.805% | |
| 2/12/2025 | Wellington Management Group LLP | 132,895 | $404K | 0.0% | +5.2% | 0.249% | |
| 2/12/2025 | JPMorgan Chase & Co. | 66,756 | $203K | 0.0% | +109.9% | 0.125% | |
| 2/11/2025 | Prudential Financial Inc. | 10,415 | $32K | 0.0% | N/A | 0.020% | |
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| 2/10/2025 | Tocqueville Asset Management L.P. | 260,870 | $793K | 0.0% | +26.8% | 0.489% | |
| 1/24/2025 | abrdn plc | 883,704 | $2.69M | 0.0% | +137.8% | 1.656% | |
| 1/24/2025 | China Universal Asset Management Co. Ltd. | 10,410 | $32K | 0.0% | N/A | 0.020% | |
| 1/23/2025 | Heck Capital Advisors LLC | 20,120 | $61K | 0.0% | N/A | 0.038% | |
| 1/17/2025 | SG Americas Securities LLC | 20,415 | $62K | 0.0% | +31.2% | 0.038% | |
| 12/26/2024 | JPMorgan Chase & Co. | 31,805 | $158K | 0.0% | +94.4% | 0.060% | |
| 11/19/2024 | Barclays PLC | 58,067 | $289K | 0.0% | +341.1% | 0.109% | |
| 11/16/2024 | Geode Capital Management LLC | 973,466 | $4.85M | 0.0% | +8.1% | 1.838% | |
| 11/15/2024 | Barclays PLC | 58,067 | $289K | 0.0% | +341.1% | 0.110% | |
| 11/15/2024 | XTX Topco Ltd | 22,438 | $112K | 0.0% | N/A | 0.042% | |