Simplify Asset Management Inc. Top Holdings and 13F Report (2021) About Simplify Asset Management Inc.Investment ActivitySimplify Asset Management Inc. has $6.11 billion in total holdings as of September 30, 2021.Simplify Asset Management Inc. owns shares of 113 different stocks, but just 3 companies or ETFs make up 80% of its holdings.Approximately 4.54% of the portfolio was purchased this quarter.About 22.42% of the portfolio was sold this quarter.This quarter, Simplify Asset Management Inc. has purchased 139 new stocks and bought additional shares in 12 stocks.Simplify Asset Management Inc. sold shares of 70 stocks and completely divested from 39 stocks this quarter.Largest Holdings SIMPLIFY EXCHANGE TRADED FUN $3,977,208,694iShares Core S&P 500 ETF $780,088,683iShares Core U.S. Aggregate Bond ETF $445,288,978ISHARES BITCOIN TRUST ETF $147,700,800SPDR Gold Shares $89,535,484 Largest New Holdings this Quarter 444859102 - Humana $24,874,548 Holding03969K108 - Arcutis Biotherapeutics $22,884,733 Holding05352A100 - Avantor $14,537,081 Holding86627T108 - Summit Therapeutics $8,625,892 Holding384747101 - GRAIL INC $6,020,816 Holding Largest Purchases this Quarter ISHARES BITCOIN TRUST ETF 1,177,300 shares (about $55.73M)SPDR Gold Shares 125,100 shares (about $47.64M)SIMPLIFY EXCHANGE TRADED FUN 1,400,000 shares (about $41.08M)Humana 65,190 shares (about $24.87M)Arcutis Biotherapeutics 865,862 shares (about $22.88M) Largest Sales this Quarter SIMPLIFY EXCHANGE TRADED FUN 9,393,624 shares (about $939.93M)Simplify Short Term Treasury Futures Strategy ETF 4,787,000 shares (about $91.14M)Simplify US Equity PLUS Upside Convexity ETF 1,075,000 shares (about $52.14M)iShares Core U.S. Aggregate Bond ETF 331,696 shares (about $31.36M)Simplify Aggregate Bond ETF 1,458,000 shares (about $27.60M) Sector Allocation Over TimeMap of 500 Largest Holdings ofSimplify Asset Management Inc. Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorSIMPLIFY EXCHANGE TRADED FUN$3,977,208,694$939,926,017 ▼-19.1%39,748,23865.1%GOVT MONE MA ETFIVViShares Core S&P 500 ETF$780,088,683$18,426,351 ▼-2.3%1,018,59212.8%ETFAGGiShares Core U.S. Aggregate Bond ETF$445,288,978$31,358,540 ▼-6.6%4,710,0597.3%ETFISHARES BITCOIN TRUST ETF$147,700,800$55,733,382 ▲60.6%3,120,0002.4%SHS BEN INTGLDSPDR Gold Shares$89,535,484$47,643,084 ▲113.7%235,1001.5%ETFSIMPLIFY EXCHANGE TRADED FUN$48,129,042$7,524,160 ▲18.5%4,477,6200.8%MULTI QIS ALTERNSIMPLIFY EXCHANGE TRADED FUN$44,010,000$41,076,000 ▲1,400.0%1,500,0000.7%US EQUI PLUS ETFSIMPLIFY EXCHANGE TRADED FUN$35,906,2860.0%1,553,3760.6%NATL MUNI BD ETFLLYEli Lilly and Company$34,814,223$17,787,791 ▲104.5%30,0880.6%HealthcarePAGPPlains GP$32,954,1240.0%1,272,3600.5%EnergySIMPLIFY EXCHANGE TRADED FUN$27,700,685$12,652,500 ▲84.1%1,149,4060.5%TARGE 15 ETFSPUCSimplify US Equity PLUS Upside Convexity ETF$27,150,882$52,137,500 ▼-65.8%559,8120.4%ETFHUMHumana$24,874,548$24,874,548 ▲New Holding65,1900.4%HealthcareARQTArcutis Biotherapeutics$22,884,733$22,884,733 ▲New Holding865,8620.4%HealthcareBUCKSimplify Treasury Option Income ETF$22,503,000$16,733,000 ▼-42.6%975,0000.4%ETFWRBYWarby Parker$17,427,422$1,118,728 ▲6.9%627,3370.3%Consumer DiscretionaryABBVAbbVie$16,810,297$52,056 ▼-0.3%64,2620.3%HealthcareJNJJohnson & Johnson$16,534,866$2,759,120 ▼-14.3%62,4570.3%HealthcareTMOThermo Fisher Scientific$16,288,956$709,478 ▲4.6%24,1300.3%HealthcareUNHUnitedHealth Group$15,198,213$296,968 ▼-1.9%41,4030.2%HealthcarePURECYCLE TECHNOLOGIES INC$14,668,785$1,226,267 ▲9.1%3,326,2550.2%COMAVTRAvantor$14,537,081$14,537,081 ▲New Holding965,9190.2%HealthcareJAZZJazz Pharmaceuticals$12,453,461$3,419,550 ▼-21.5%53,7900.2%HealthcareAGGHSimplify Aggregate Bond ETF$12,325,834$27,599,940 ▼-69.1%651,1270.2%ETFGILDGilead Sciences$12,082,142$39,349 ▼-0.3%81,0610.2%HealthcareDGXQuest Diagnostics$11,545,822$41,253 ▼-0.4%49,5380.2%HealthcareBENITEC BIOPHARMA INC$10,022,010$33,560 ▼-0.3%1,002,2010.2%COM NEWSIMPLIFY EXCHANGE TRADED FUN$10,020,2360.0%428,0780.2%CHINA A SHS PLUSAMGNAmgen$8,816,725$24,026 ▼-0.3%20,9170.1%HealthcareGHGuardant Health$8,728,938$3,811,375 ▲77.5%48,9400.1%HealthcareUTHRUnited Therapeutics$8,715,759$15,892,008 ▼-64.6%16,0840.1%HealthcareSMMTSummit Therapeutics$8,625,892$8,625,892 ▲New Holding510,1060.1%HealthcareACHVAchieve Life Sciences$7,540,729$4,045,000 ▼-34.9%932,1050.1%HealthcareBHVNBiohaven$7,351,752$6,535,653 ▼-47.1%550,6930.1%HealthcareTXG10x Genomics$6,166,076$20,303,802 ▼-76.7%68,2390.1%HealthcareGRAIL INC$6,020,816$6,020,816 ▲New Holding42,9690.1%COMCVSCVS Health$5,992,559$99,143 ▼-1.6%69,9330.1%HealthcareCAHCardinal Health$5,955,836$20,867 ▼-0.3%26,8300.1%HealthcareVRTXVertex Pharmaceuticals$5,451,863$14,639 ▼-0.3%10,4280.1%HealthcareVANECK BITCOIN ETF$4,153,412$2,092,354 ▼-33.5%175,8430.1%SH BEN INTESTAEstablishment Labs$3,871,569$13,283 ▼-0.3%60,3330.1%HealthcareDCTHDelcath Systems$3,636,034$592,343 ▼-14.0%227,6790.1%HealthcareTSLATesla$3,606,644$161,793 ▼-4.3%10,1650.1%Consumer DiscretionarySIMPLIFY EXCHANGE TRADED FUN$3,494,744$26,039,170 ▼-88.2%97,3030.1%NEXT INTANGIBLEGEHCGE HealthCare Technologies$3,391,199$10,655 ▼-0.3%51,8770.1%HealthcareHSICHenry Schein$3,190,776$3,190,776 ▲New Holding37,9990.1%HealthcareSIMPLIFY EXCHANGE TRADED FUN$3,015,5410.0%91,4640.0%PIPE SAND SM ETFMISTMilestone Pharmaceuticals$2,899,5570.0%3,349,3790.0%HealthcareELVElevance Health$2,844,607$7,100,242 ▼-71.4%7,3160.0%HealthcareSIMPLIFY EXCHANGE TRADED FUN$2,676,0050.0%116,5000.0%ANCORATO TARGETCORTCorcept Therapeutics$2,370,051$675,939 ▼-22.2%20,5680.0%HealthcareRITMRithm Capital$2,341,022$1,231,605 ▼-34.5%269,7030.0%FinanceQQQInvesco QQQ$2,219,3100.0%3,0000.0%ETFDHRDanaher$2,105,833$7,384,041 ▼-77.8%9,5050.0%HealthcarePCRXPacira BioSciences$2,074,491$6,738 ▼-0.3%82,8140.0%HealthcareCOLLCollegium Pharmaceutical$2,040,628$2,040,628 ▲New Holding93,5210.0%HealthcareSIMPLIFY EXCHANGE TRADED FUN$1,828,875$1,828,875 ▲New Holding75,0000.0%TAXAWARE DIV INCPHATPhathom Pharmaceuticals$1,819,6490.0%249,2670.0%HealthcareEWEdwards Lifesciences$1,607,019$4,402 ▼-0.3%18,6170.0%HealthcareINSMInsmed$1,586,318$33,329 ▼-2.1%13,8980.0%HealthcareABEOAbeona Therapeutics$1,450,748$362,686 ▼-20.0%276,3330.0%HealthcareOBIOOrchestra BioMed$1,364,5870.0%219,3870.0%HealthcareAQSTAquestive Therapeutics$1,290,4870.0%278,7230.0%HealthcareKYVERNA THERAPEUTICS INC$1,241,7000.0%182,6030.0%COMTGTXTG Therapeutics$1,183,150$3,235 ▼-0.3%21,2110.0%HealthcareIVAInventiva$1,156,7520.0%313,4830.0%HealthcareCMPSCompass Pathways$1,124,340$297,316 ▼-20.9%90,3810.0%HealthcareBHRBRAEMAR HOTELS & RESORTS$1,090,510$784,900 ▲256.8%653,0000.0%Real EstateCABACabaletta Bio$1,067,971$1,067,971 ▲New Holding556,2350.0%HealthcareFLLFull House Resorts$862,650$298,910 ▲53.0%607,5000.0%Consumer DiscretionaryPROKIDNEY CORP$803,010$803,010 ▲New Holding483,7410.0%SHS CL APALANTIR TECHNOLOGIES INC$788,790$1,459,738 ▼-64.9%4,2170.0%CL ACOOPER COS INC$743,143$2,035 ▼-0.3%13,1460.0%COMARTIVA BIOTHERAPEUTICS INC$721,6480.0%101,3550.0%COMCLDXCelldex Therapeutics$700,996$1,021,077 ▼-59.3%21,6290.0%HealthcareCSCOCisco Systems$698,949$1,120,428 ▼-61.6%6,4940.0%TechnologyAGILON HEALTH INC$669,034$1,831 ▼-0.3%8,4060.0%COM NEWWALMART INC$660,516$1,094,694 ▼-62.4%6,3560.0%COMOCULOcular Therapeutix$621,6610.0%81,0510.0%HealthcareSYKStryker$617,975$1,652 ▼-0.3%2,2440.0%HealthcarePALISADE BIO INC$586,350$21,884 ▼-3.6%434,3330.0%COMDXDynex Capital$567,182$931,148 ▼-62.1%50,9140.0%FinanceFULCFulcrum Therapeutics$567,173$1,865 ▼-0.3%153,2900.0%HealthcareDELLDell Technologies$551,937$1,154,441 ▼-67.7%1,0260.0%TechnologyARMOUR RESIDENTIAL REIT INC$551,139$194,298 ▼-26.1%39,8510.0%COM SHSLEONABIO INC$532,9260.0%149,2790.0%COMNLYAnnaly Capital Management$518,474$838,565 ▼-61.8%27,4470.0%FinanceMFAMFA Financial$516,318$800,488 ▼-60.8%65,7730.0%FinanceBRK.BBerkshire Hathaway$486,497$839,045 ▼-63.3%9770.0%FinanceNBIXNeurocrine Biosciences$468,923$1,277 ▼-0.3%3,3060.0%HealthcareTUASimplify Short Term Treasury Futures Strategy ETF$452,010$91,144,561 ▼-99.5%23,7400.0%ETFAGNCAGNC Investment$431,750$615,699 ▼-58.8%47,6020.0%FinanceCRWDCrowdStrike$406,391$406,391 ▲New Holding1,5350.0%TechnologyZBHZimmer Biomet$389,342$1,066 ▼-0.3%4,3830.0%HealthcarePMTPennyMac Mortgage Investment Trust$374,300$47,280 ▼-11.2%47,5000.0%FinanceSTXSeagate Technology$363,402$549,715 ▼-60.2%3940.0%TechnologyABTAbbott Laboratories$334,737$1,695,823 ▼-83.5%3,3870.0%HealthcareSAB BIOTHERAPEUTICS INC$332,3710.0%104,8490.0%COM NEWUPSTREAM BIO INC$327,3360.0%62,1130.0%COMIBMInternational Business Machines$326,376$776,353 ▼-70.4%1,4840.0%TechnologyShowing largest 100 holdings. 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