Simplify Asset Management Inc. Top Holdings and 13F Report (2021) About Simplify Asset Management Inc.Investment ActivitySimplify Asset Management Inc. has $6.52 billion in total holdings as of September 30, 2021.Simplify Asset Management Inc. owns shares of 142 different stocks, but just 2 companies or ETFs make up 80% of its holdings.Approximately 10.12% of the portfolio was purchased this quarter.About 2.61% of the portfolio was sold this quarter.This quarter, Simplify Asset Management Inc. has purchased 141 new stocks and bought additional shares in 22 stocks.Simplify Asset Management Inc. sold shares of 71 stocks and completely divested from 34 stocks this quarter.Largest Holdings SIMPLIFY EXCHANGE TRADED FUN $4,606,639,826iShares Core S&P 500 ETF $713,479,074iShares Core U.S. Aggregate Bond ETF $407,013,552Simplify Short Term Treasury Futures Strategy ETF $116,655,570Simplify US Equity PLUS Upside Convexity ETF $72,225,994 Largest New Holdings this Quarter 82889N657 - Simplify Short Term Treasury Futures Strategy ETF $116,655,570 Holding82889N640 - Simplify Treasury Option Income ETF $39,958,500 Holding670100205 - Novo Nordisk A/S $12,030,370 HoldingG0593M107 - AstraZeneca $5,091,826 Holding82889N699 - Simplify Managed Futures Strategy ETF $4,574,734 Holding Largest Purchases this Quarter SIMPLIFY EXCHANGE TRADED FUN 2,389,735 shares (about $239.12M)iShares Core U.S. Aggregate Bond ETF 1,299,935 shares (about $129.04M)Simplify Short Term Treasury Futures Strategy ETF 5,528,700 shares (about $116.66M)iShares Core S&P 500 ETF 82,160 shares (about $53.67M)Simplify Treasury Option Income ETF 1,700,000 shares (about $39.96M) Largest Sales this Quarter UnitedHealth Group 96,906 shares (about $26.22M)Regeneron Pharmaceuticals 20,253 shares (about $15.65M)Amgen 36,506 shares (about $12.84M)Eli Lilly and Company 11,276 shares (about $10.37M)ISHARES BITCOIN TRUST ETF 120,000 shares (about $4.62M) Sector Allocation Over TimeMap of 500 Largest Holdings ofSimplify Asset Management Inc. Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorSIMPLIFY EXCHANGE TRADED FUN$4,606,639,826$239,116,884 â–²5.5%46,038,77570.7%GOVERNMENT MONEYIVViShares Core S&P 500 ETF$713,479,074$53,667,734 â–²8.1%1,092,26610.9%ETFAGGiShares Core U.S. Aggregate Bond ETF$407,013,552$129,044,548 â–²46.4%4,100,0666.2%FinanceTUASimplify Short Term Treasury Futures Strategy ETF$116,655,570$116,655,570 â–²New Holding5,528,7001.8%ETFSPUCSimplify US Equity PLUS Upside Convexity ETF$72,225,9940.0%1,634,8121.1%ETFISHARES BITCOIN TRUST ETF$56,840,000$4,624,271 â–¼-7.5%1,475,0000.9%SHS BEN INTSIMPLIFY EXCHANGE TRADED FUN$45,792,3100.0%3,777,6200.7%MULTI QIS ALTERNAGGHSimplify Aggregate Bond ETF$42,920,734$5,087,500 â–²13.4%2,109,1270.7%ETFBUCKSimplify Treasury Option Income ETF$39,958,500$39,958,500 â–²New Holding1,700,0000.6%ETFSIMPLIFY EXCHANGE TRADED FUN$37,530,4960.0%1,553,3760.6%NATL MUNI BD ETFPAGPPlains GP$30,892,9010.0%1,272,3600.5%EnergySIMPLIFY EXCHANGE TRADED FUN$24,416,8900.0%822,3030.4%NEXT INTANGIBLEUTHRUnited Therapeutics$20,310,158$6,174,108 â–²43.7%34,2510.3%MedicalALGNAlign Technology$18,325,353$50,915 â–¼-0.3%106,8970.3%MedicalLLYEli Lilly and Company$15,362,918$10,371,326 â–¼-40.3%16,7030.2%MedicalSIMPLIFY EXCHANGE TRADED FUN$14,711,0050.0%624,4060.2%TARGET 15 DISTRINVONovo Nordisk A/S$12,030,370$12,030,370 â–²New Holding327,3570.2%MedicalABBVAbbVie$10,574,581$5,403,321 â–²104.5%48,6210.2%MedicalJAZZJazz Pharmaceuticals$9,779,556$3,676,644 â–¼-27.3%51,7300.2%MedicalPURECYCLE TECHNOLOGIES INC$9,190,338$844,859 â–¼-8.4%1,770,7780.1%COMTMOThermo Fisher Scientific$8,557,046$6,286,669 â–²276.9%17,4090.1%MedicalGILDGilead Sciences$8,549,653$3,326,205 â–²63.7%61,3450.1%MedicalREGNRegeneron Pharmaceuticals$8,421,776$15,648,278 â–¼-65.0%10,9000.1%MedicalJNJJohnson & Johnson$8,096,097$2,728,195 â–²50.8%33,1210.1%MedicalBHVNBiohaven$7,600,464$505,925 â–¼-6.2%898,4000.1%MedicalTXG10x Genomics$7,530,345$2,786,947 â–¼-27.0%354,7030.1%MedicalMMM3M$6,425,120$5,773,763 â–²886.4%44,2410.1%Multi-Sector ConglomeratesWRBYWarby Parker$6,127,809$2,307,418 â–¼-27.4%290,8310.1%Consumer StaplesDHRDanaher$6,124,838$2,296,435 â–¼-27.3%32,3040.1%MedicalBENITEC BIOPHARMA INC$5,987,877$4,377,991 â–²271.9%562,2420.1%COM NEWAMGNAmgen$5,574,711$12,844,635 â–¼-69.7%15,8440.1%MedicalAZNCFAstraZeneca$5,091,826$5,091,826 â–²New Holding25,8180.1%MedicalISRGIntuitive Surgical$4,963,479$1,831,513 â–¼-27.0%10,7670.1%MedicalCTASimplify Managed Futures Strategy ETF$4,574,734$4,574,734 â–²New Holding151,3810.1%ETFEYPTEyepoint Pharmaceuticals$4,203,970$633,183 â–¼-13.1%326,1420.1%MedicalTSLATesla$4,124,194$650,191 â–¼-13.6%11,0940.1%Auto/Tires/TrucksVANECK BITCOIN ETF$4,007,333$310,794 â–²8.4%209,1510.1%SH BEN INTCVSCVS Health$3,879,214$1,444,372 â–¼-27.1%54,0130.1%MedicalVRTXVertex Pharmaceuticals$3,543,741$4,267,136 â–¼-54.6%7,9360.1%MedicalACHVAchieve Life Sciences$3,482,4650.0%1,184,5120.1%MedicalALHCAlignment Healthcare$3,401,224$1,230,722 â–¼-26.6%193,0320.1%MedicalRITMRithm Capital$3,190,902$2,085,600 â–²188.7%336,5930.0%FinanceESTAEstablishment Labs$3,009,851$1,129,070 â–¼-27.3%53,0090.0%MedicalPHATPhathom Pharmaceuticals$2,915,108$661,589 â–¼-18.5%262,3860.0%MedicalSIMPLIFY EXCHANGE TRADED FUN$2,832,5000.0%125,0000.0%ANCORATO TARGETGEHCGE HealthCare Technologies$2,794,527$1,051,186 â–¼-27.3%39,2600.0%MedicalSIMPLIFY EXCHANGE TRADED FUN$2,678,2400.0%100,0000.0%US EQUITY PLUS MSIMPLIFY EXCHANGE TRADED FUN$2,612,5960.0%91,4640.0%PIPER SANDLER USDCTHDelcath Systems$2,423,2490.0%261,1260.0%MedicalABEOAbeona Therapeutics$2,275,786$34,254 â–²1.5%507,9880.0%MedicalCLDXCelldex Therapeutics$2,188,490$507,710 â–¼-18.8%68,9940.0%MedicalMFAMFA Financial$2,002,220$62,270 â–²3.2%209,0000.0%FinanceGHGuardant Health$1,923,236$809,161 â–¼-29.6%20,8210.0%MedicalMISTMilestone Pharmaceuticals$1,792,6220.0%1,506,4050.0%MedicalOCSOculis$1,772,676$853,486 â–¼-32.5%66,6670.0%MedicalWALMART INC$1,766,889$158,706 â–¼-8.2%14,2170.0%COMINSMInsmed$1,763,236$4,269,016 â–¼-70.8%10,7830.0%MedicalPALANTIR TECHNOLOGIES INC$1,712,061$287,148 â–²20.2%11,7040.0%CL AABTAbbott Laboratories$1,592,001$597,950 â–¼-27.3%15,5060.0%MedicalCSCOCisco Systems$1,540,860$38,873 â–¼-2.5%19,8590.0%Computer and TechnologyLEONABIO INC$1,534,5880.0%149,2790.0%COMCORTCorcept Therapeutics$1,522,227$1,522,227 â–²New Holding37,7630.0%MedicalKYVERNA THERAPEUTICS INC$1,493,905$165,981 â–¼-10.0%173,1060.0%COMPCRXPacira BioSciences$1,415,958$533,541 â–¼-27.4%62,6530.0%MedicalIVAInventiva$1,264,973$609,052 â–¼-32.5%227,9230.0%MedicalBRK.BBerkshire Hathaway$1,256,462$1,256,462 â–²New Holding2,6220.0%FinanceIBMInternational Business Machines$1,161,048$15,028 â–¼-1.3%4,7900.0%Computer and TechnologyEWEdwards Lifesciences$1,127,366$421,221 â–¼-27.2%14,0780.0%MedicalVRDNViridian Therapeutics$1,099,878$925,188 â–¼-45.7%56,2310.0%MedicalNLYAnnaly Capital Management$1,044,873$639,830 â–¼-38.0%49,4030.0%FinanceDXDynex Capital$1,040,948$324,372 â–¼-23.8%81,5790.0%FinanceAGNCAGNC Investment$1,037,955$236,227 â–¼-18.5%103,4850.0%FinanceOXFORD LANE CAP CORP$978,000$978,000 â–²New Holding100,0000.0%COMAQSTAquestive Therapeutics$972,258$972,258 â–²New Holding234,2790.0%MedicalVOR BIOPHARMA INC$954,618$954,618 â–²New Holding53,5100.0%COM NEWZVRAZevra Therapeutics$937,872$543,030 â–²137.5%100,6300.0%MedicalOBIOOrchestra BioMed$932,395$932,395 â–²New Holding219,3870.0%MedicalARMOUR RESIDENTIAL REIT INC$899,052$401,988 â–¼-30.9%53,9000.0%COM SHSFULCFulcrum Therapeutics$889,674$335,026 â–¼-27.4%115,9940.0%MedicalCMPSCompass Pathways$879,558$724,143 â–¼-45.2%159,0520.0%MedicalXOMExxonMobil$826,414$506,775 â–¼-38.0%4,8710.0%EnergyMRKMerck & Co., Inc.$787,178$787,178 â–²New Holding6,5440.0%MedicalUNHUnitedHealth Group$784,982$26,221,808 â–¼-97.1%2,9010.0%MedicalTRVITrevi Therapeutics$780,365$780,365 â–²New Holding65,4120.0%MedicalMAMastercard$762,481$84,443 â–¼-10.0%1,5260.0%Business ServicesOCULOcular Therapeutix$762,300$762,300 â–²New Holding90,0000.0%MedicalQCOMQualcomm$717,820$22,021 â–²3.2%5,5740.0%Computer and TechnologySAB BIOTHERAPEUTICS INC$717,091$80,419 â–¼-10.1%187,2300.0%COM NEWCOOPER COS INC$710,853$264,550 â–¼-27.1%9,9420.0%COMBSXBoston Scientific$710,581$265,244 â–¼-27.2%11,3240.0%MedicalUPSTREAM BIO INC$700,137$700,137 â–²New Holding77,7930.0%COMFDMT4D Molecular Therapeutics$655,703$655,703 â–²New Holding70,4300.0%MedicalCHIMERA INVT CORP$640,3640.0%51,0250.0%COM SHSPANWPalo Alto Networks$635,989$635,989 â–²New Holding3,9670.0%Computer and TechnologyPALISADE BIO INC$612,500$612,500 â–²New Holding350,0000.0%COMINTUIntuit$612,250$22,484 â–¼-3.5%1,4160.0%Computer and TechnologyNOWServiceNow$566,766$53,111 â–¼-8.6%5,4210.0%Computer and TechnologySYKStryker$561,889$205,040 â–¼-26.7%1,7100.0%MedicalADBEAdobe$550,819$550,819 â–²New Holding2,2660.0%Computer and TechnologyTGTXTG Therapeutics$533,148$238,653 â–¼-30.9%16,0490.0%MedicalShowing largest 100 holdings. 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