NASDAQ:TSHA Taysha Gene Therapies (TSHA) Stock Price, News & Analysis $3.58 -0.56 (-13.53%) Closing price 04:00 PM EasternExtended Trading$3.61 +0.03 (+0.84%) As of 07:59 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsInsider TradesNews and TrendsOptions ChainOwnershipSEC FilingsShort Interest About Taysha Gene Therapies Stock (NASDAQ:TSHA) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Taysha Gene Therapies alerts:Sign Up Key Stats Today's Range$3.55▼$4.1350-Day Range$4.14▼$6.6852-Week Range$3.55▼$7.30Volume6.12 million shsAverage Volume4.70 million shsMarket Capitalization$1.17 billionP/E RatioN/ADividend YieldN/APrice Target$12.77Consensus RatingBuy Company Overview Taysha Gene Therapies, Inc. (NASDAQ: TSHA) is a clinical-stage biotechnology company focused on developing gene therapies for severe monogenic diseases of the central nervous system. The company uses adeno-associated virus-based delivery technologies and other genetic medicine approaches to target conditions with limited or no approved treatment options. Taysha’s research and development programs have included TSHA-102, an investigational gene therapy being developed for Rett syndrome, as well as programs for other rare neurological disorders. Its candidates are designed to deliver therapeutic genetic material to affected cells, with the goal of addressing the underlying causes of disease rather than treating symptoms alone. The company’s therapies remain investigational and are subject to clinical and regulatory review. Founded in 2019 and headquartered in Dallas, Texas, Taysha was established in collaboration with researchers at UT Southwestern Medical Center. The company’s operations are primarily focused on advancing its pipeline through clinical development and regulatory processes in the United States, with potential global applications for rare neurological diseases. R.A. Session serves as president and chief executive officer.AI Generated. May Contain Errors. Read More Taysha Gene Therapies Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks45th Percentile Overall ScoreTSHA MarketRank™: 2.266806999075 of 5 starsTaysha Gene Therapies scored higher than 45% of companies evaluated by MarketBeat, and ranked 625th out of 877 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion4.1 / 5Analyst RatingBuy Consensus RatingTaysha Gene Therapies has received a consensus rating of Buy. The company's average rating score is 3.00, and is based on 2 strong buy ratings, 12 buy ratings, no hold ratings, and 1 sell rating.Upside PotentialTaysha Gene Therapies has a consensus price target of $12.77, representing about 256.7% upside from its current price of $3.58.Amount of Analyst CoverageTaysha Gene Therapies has only been the subject of 3 research reports in the past 90 days.Read more about Taysha Gene Therapies' stock forecast and price target. Earnings and Valuation0.6 / 5Proj. Earnings GrowthGrowing Earnings GrowthEarnings for Taysha Gene Therapies are expected to grow in the coming year, from ($0.52) to ($0.49) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Taysha Gene Therapies is -8.52, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Taysha Gene Therapies is -8.52, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioTaysha Gene Therapies has a P/B Ratio of 3.98. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.Read more about Taysha Gene Therapies' valuation and earnings. Short Interest0.0 / 5Short Interest LevelBearish Percentage of Shares Shorted17.49% of the float of Taysha Gene Therapies has been sold short.Short Interest Ratio / Days to CoverTaysha Gene Therapies has a short interest ratio ("days to cover") of 11.15, which indicates bearish sentiment.Change versus previous monthShort interest in Taysha Gene Therapies has recently increased by 7.03%, indicating that investor sentiment is decreasing significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldTaysha Gene Therapies does not currently pay a dividend.Dividend GrowthTaysha Gene Therapies does not have a long track record of dividend growth. News and Social Media3.0 / 5News Sentiment0.79 News SentimentTaysha Gene Therapies has a news sentiment score of 0.79. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This news sentiment score is similar to the average news sentiment of Healthcare companies.News Coverage This WeekMarketBeat has tracked 7 news articles for Taysha Gene Therapies this week, compared to 3 articles on an average week.Search InterestOnly 1 people have searched for TSHA on MarketBeat in the last 30 days. This is a decrease of -67% compared to the previous 30 days.MarketBeat Follows8 people have added Taysha Gene Therapies to their MarketBeat watchlist in the last 30 days. This is an increase of 300% compared to the previous 30 days. Company Ownership0.8 / 5Insider TradingN/A Insider Buying vs. Insider SellingIn the past three months, Taysha Gene Therapies insiders have not sold or bought any company stock.Percentage Held by Insiders3.48% of the stock of Taysha Gene Therapies is held by insiders.Percentage Held by Institutions77.70% of the stock of Taysha Gene Therapies is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about Taysha Gene Therapies' insider trading history. Receive TSHA Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Taysha Gene Therapies and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsSMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. By entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. TSHA Stock News HeadlinesTaysha Gene Therapies (TSHA) Stock May Be Above Fair Value On Book ValueOctober 9, 2026 | finance.yahoo.comTaysha Gene Therapies (TSHA) Faces A Split Valuation Debate, Is It Really 66% Below Fair Value?October 9, 2026 | finance.yahoo.comThe end may be near for these iconic stocksMarc Chaikin, founder of Chaikin Analytics, says two forces - AI disruption and fracturing global trade - are triggering a historic wealth transfer already underway in 2026. Household names like Intuit (-57%), Boston Scientific (-49%), and Tractor Supply (-40%) are cratering, while lesser-known companies like Sandisk (+573%) and Rackspace (+444%) surge. Chaikin has identified specific stocks he believes investors should sell before they fall further - and the names may surprise you. He's also pinpointing a company tapped as Nvidia's self-driving partner and a potential AI megadeal that could split into three high-growth stocks. Stream his free presentation to get every buy and sell recommendation with no membership or credit card required.October 13 at 1:00 AM | Chaikin Analytics (Ad)Comparing MediWound (NASDAQ:MDWD) and Taysha Gene Therapies (NASDAQ:TSHA)October 9, 2026 | americanbankingnews.comTaysha Gene Therapies, Inc. (NASDAQ:TSHA) Receives Average Recommendation of "Buy" from BrokeragesOctober 7, 2026 | americanbankingnews.comTaysha Gene Therapies Announces Inducement Grant under Nasdaq Listing Rule 5635(4)October 6, 2026 | marketscreener.comMTaysha Gene Therapies (NASDAQ:TSHA) Stock Price Down 5.4% - Time to Sell?October 5, 2026 | americanbankingnews.comAnalyzing Amylyx Pharmaceuticals (NASDAQ:AMLX) and Taysha Gene Therapies (NASDAQ:TSHA)October 5, 2026 | americanbankingnews.comSee More Headlines TSHA Stock Analysis - Frequently Asked Questions How have TSHA shares performed this year? Taysha Gene Therapies' stock was trading at $5.50 at the beginning of the year. Since then, TSHA shares have decreased by 34.9% and is now trading at $3.58. How were Taysha Gene Therapies' earnings last quarter? Taysha Gene Therapies, Inc. (NASDAQ:TSHA) released its quarterly earnings data on Tuesday, August, 11th. The company reported ($0.13) EPS for the quarter, missing analysts' consensus estimates of ($0.11) by $0.02. Read the conference call transcript. When did Taysha Gene Therapies IPO? Taysha Gene Therapies (TSHA) raised $150 million in an IPO on Thursday, September 24th 2020. The company issued 7,869,566 shares at a price of $18.00-$20.00 per share. Goldman Sachs, Morgan Stanley and Jefferies served as the underwriters for the IPO and Chardan was co-manager. How do I buy shares of Taysha Gene Therapies? Shares of TSHA stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Taysha Gene Therapies own? Based on aggregate information from My MarketBeat watchlists, some other companies that Taysha Gene Therapies investors own include NVIDIA (NVDA), Advanced Micro Devices (AMD), Palantir Technologies (PLTR), Micron Technology (MU), Tesla (TSLA), Plug Power (PLUG) and SoFi Technologies (SOFI). Company Calendar Last Earnings8/11/2026Today10/13/2026Next Earnings (Estimated)11/03/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Green Zone (17m+) 1-Year History Oct 25 Jan 26 Apr 26 Jul 26 Oct 26 TSHA's financial health is in the Green zone, according to TradeSmith. TSHA has been in this zone for over 17 months. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorHealthcare Industry Biotechnology Sub-IndustryBiotechnology Current SymbolNASDAQ:TSHA CIK1806310 Webwww.tayshagtx.com Phone214-612-0000FaxN/AEmployees99Year Founded2020Price Target and Rating Average Price Target for Taysha Gene Therapies$12.77 High Price Target$17.00 Low Price Target$10.00 Potential Upside/Downside+256.7%Consensus RatingBuy Rating Score (0-4)3.00 Research Coverage15 Analysts Profitability EPS (Trailing Twelve Months)($0.42) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income-$109 million Net MarginsN/A Pretax Margin-2,728.04% Return on Equity-56.19% Return on Assets-41.84% Debt Debt-to-Equity Ratio0.13 Current Ratio17.76 Quick Ratio17.76 Sales & Book Value Annual Sales$9.77 million Price / Sales119.39 Cash FlowN/A Price / Cash FlowN/A Book Value$0.90 per share Price / Book3.98Miscellaneous Outstanding Shares325,830,000Free Float314,495,000Market Cap$1.17 billion OptionableOptionable Beta1.19 Social Links 10 Stocks Powering The Next AI Boom The AI boom is creating opportunities across semiconductors, cloud computing, enterprise software, infrastructure, cybersecurity, and automation. Inside this report, you’ll find 10 companies positioned to benefit as artificial intelligence moves from hype to real-world deployment and becomes a core growth driver for corporate America.Get This Free Report This page (NASDAQ:TSHA) was last updated on 10/13/2026 by MarketBeat.com Staff. From Our PartnersALERT: Drop these 5 stocks before the market opens tomorrow!The Wall Street Journal is already raising the alarm about a potential market crash, and Weiss Ratings researc...Weiss Ratings | SponsoredTrump's New DollarPorter Stansberry says President Trump has signed an executive order initiating what he calls a full U.S. doll...Porter & Company | SponsoredSmall Colorado Company (Backed by Sam Altman) Could Save U.S. Power GridA small Colorado company has secured rights to technology that could prevent the U.S. public power grid from c...Altimetry | SponsoredReady to give options a try? 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