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Xeris Biopharma (XERS) Competitors

Xeris Biopharma logo
$7.68 +0.38 (+5.21%)
Closing price 08/15/2025 04:00 PM Eastern
Extended Trading
$7.60 -0.08 (-1.04%)
As of 08/15/2025 07:56 PM Eastern
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XERS vs. PTGX, AAPG, HCM, INDV, APLS, MOR, KYMR, RARE, IMVT, and ALVO

Should you be buying Xeris Biopharma stock or one of its competitors? The main competitors of Xeris Biopharma include Protagonist Therapeutics (PTGX), Ascentage Pharma Group International (AAPG), HUTCHMED (HCM), Indivior (INDV), Apellis Pharmaceuticals (APLS), MorphoSys (MOR), Kymera Therapeutics (KYMR), Ultragenyx Pharmaceutical (RARE), Immunovant (IMVT), and Alvotech (ALVO). These companies are all part of the "pharmaceutical products" industry.

Xeris Biopharma vs. Its Competitors

Protagonist Therapeutics (NASDAQ:PTGX) and Xeris Biopharma (NASDAQ:XERS) are both medical companies, but which is the better stock? We will contrast the two companies based on the strength of their institutional ownership, profitability, analyst recommendations, dividends, valuation, earnings, media sentiment and risk.

Protagonist Therapeutics has a net margin of 24.88% compared to Xeris Biopharma's net margin of -13.01%. Protagonist Therapeutics' return on equity of 8.12% beat Xeris Biopharma's return on equity.

Company Net Margins Return on Equity Return on Assets
Protagonist Therapeutics24.88% 8.12% 7.41%
Xeris Biopharma -13.01%N/A -8.00%

In the previous week, Xeris Biopharma had 14 more articles in the media than Protagonist Therapeutics. MarketBeat recorded 26 mentions for Xeris Biopharma and 12 mentions for Protagonist Therapeutics. Protagonist Therapeutics' average media sentiment score of 1.14 beat Xeris Biopharma's score of 0.87 indicating that Protagonist Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Protagonist Therapeutics
5 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
Xeris Biopharma
9 Very Positive mention(s)
3 Positive mention(s)
6 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Protagonist Therapeutics has higher earnings, but lower revenue than Xeris Biopharma. Xeris Biopharma is trading at a lower price-to-earnings ratio than Protagonist Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Protagonist Therapeutics$209.18M16.68$275.19M$0.7080.10
Xeris Biopharma$246.03M5.04-$54.84M-$0.21-36.57

98.6% of Protagonist Therapeutics shares are owned by institutional investors. Comparatively, 42.8% of Xeris Biopharma shares are owned by institutional investors. 4.9% of Protagonist Therapeutics shares are owned by company insiders. Comparatively, 6.5% of Xeris Biopharma shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

Protagonist Therapeutics presently has a consensus target price of $67.20, suggesting a potential upside of 19.85%. Xeris Biopharma has a consensus target price of $6.58, suggesting a potential downside of 14.28%. Given Protagonist Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Protagonist Therapeutics is more favorable than Xeris Biopharma.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Protagonist Therapeutics
0 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
1 Strong Buy rating(s)
3.00
Xeris Biopharma
0 Sell rating(s)
1 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.83

Protagonist Therapeutics has a beta of 2.33, suggesting that its stock price is 133% more volatile than the S&P 500. Comparatively, Xeris Biopharma has a beta of 0.65, suggesting that its stock price is 35% less volatile than the S&P 500.

Summary

Protagonist Therapeutics beats Xeris Biopharma on 14 of the 17 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding XERS and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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XERS vs. The Competition

MetricXeris BiopharmaMED IndustryMedical SectorNASDAQ Exchange
Market Cap$1.24B$2.75B$5.67B$9.82B
Dividend YieldN/A1.77%3.79%4.07%
P/E Ratio-36.5721.8930.5825.12
Price / Sales5.04740.48464.45115.80
Price / CashN/A177.1637.4059.05
Price / Book-64.005.079.096.18
Net Income-$54.84M$31.61M$3.25B$264.89M
7 Day Performance12.28%25.12%7.32%4.18%
1 Month Performance46.01%3.84%5.42%1.99%
1 Year Performance185.50%10.43%30.66%24.22%

Xeris Biopharma Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
XERS
Xeris Biopharma
3.4233 of 5 stars
$7.68
+5.2%
$6.58
-14.3%
+193.1%$1.24B$246.03M-36.57290News Coverage
Analyst Forecast
Insider Trade
Analyst Revision
PTGX
Protagonist Therapeutics
2.063 of 5 stars
$53.83
flat
$66.10
+22.8%
+38.1%$3.34B$434.43M71.77120Positive News
AAPG
Ascentage Pharma Group International
N/A$37.60
+1.1%
N/AN/A$3.25B$134.35M0.00600News Coverage
Gap Up
HCM
HUTCHMED
2.8642 of 5 stars
$17.28
+0.1%
$28.00
+62.0%
-16.3%$3.01B$630.20M0.001,811Positive News
INDV
Indivior
2.3798 of 5 stars
$21.22
+0.8%
$17.75
-16.4%
+92.0%$2.90B$1.17B34.231,051
APLS
Apellis Pharmaceuticals
3.9994 of 5 stars
$24.26
+5.7%
$36.83
+51.8%
-26.2%$2.90B$781.37M-13.33770Short Interest ↑
MOR
MorphoSys
N/A$18.96
flat
N/AN/A$2.86B$238.28M-5.45730
KYMR
Kymera Therapeutics
2.8086 of 5 stars
$43.66
+1.6%
$59.11
+35.4%
-3.2%$2.80B$47.07M-14.08170Trending News
Earnings Report
Analyst Downgrade
Analyst Revision
RARE
Ultragenyx Pharmaceutical
4.6668 of 5 stars
$28.46
+0.1%
$83.08
+191.9%
-42.6%$2.69B$560.23M-4.841,294
IMVT
Immunovant
2.9059 of 5 stars
$16.09
+2.4%
$36.40
+126.2%
-50.7%$2.69BN/A-5.87120News Coverage
Earnings Report
Analyst Forecast
Analyst Revision
ALVO
Alvotech
2.7885 of 5 stars
$8.87
+0.9%
$14.00
+57.8%
-32.8%$2.65B$491.98M23.971,032Trending News
Earnings Report
Short Interest ↓

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This page (NASDAQ:XERS) was last updated on 8/16/2025 by MarketBeat.com Staff
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