| 5/19/2025 | UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC | 1,569,100 | $3.53M | 0.0% | +62.6% | 0.987% | |
| 5/16/2025 | Woodline Partners LP | 947,986 | $2.13M | 0.0% | +53.2% | 0.596% | |
| 5/16/2025 | Goldman Sachs Group Inc. | 2,125,920 | $4.78M | 0.0% | +0.3% | 1.337% | |
| 5/16/2025 | 683 Capital Management LLC | 4,635,000 | $10.43M | 0.7% | +1.9% | 2.915% | |
| 5/16/2025 | Adage Capital Partners GP L.L.C. | 1,700,756 | $3.83M | 0.0% | -80.5% | 1.070% | |
| 5/15/2025 | Frazier Life Sciences Management L.P. | 7,819,863 | $17.60M | 0.8% | +53.4% | 4.918% | |
| 5/15/2025 | Tema Etfs LLC | 654,666 | $1.47M | 0.4% | -26.5% | 0.412% | |
| 5/14/2025 | Forefront Analytics LLC | 47,630 | $107K | 0.1% | +37.1% | 0.030% | |
| 5/13/2025 | Tejara Capital Ltd | 2,521,324 | $5.67M | 2.2% | +8.8% | 1.586% | |
| 5/13/2025 | Aberdeen Group plc | 2,188,354 | $4.92M | 0.0% | N/A | 1.376% | |
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| 5/12/2025 | Knott David M Jr | 319,337 | $719K | 0.3% | -3.5% | 0.201% | |
| 5/9/2025 | BIT Capital GmbH | 101,070 | $227K | 0.0% | N/A | 0.064% | |
| 5/8/2025 | Monaco Asset Management SAM | 416,468 | $937K | 0.2% | +9.2% | 0.262% | |
| 4/15/2025 | Avanza Fonder AB | 28,121 | $67K | 0.0% | +43.5% | 0.018% | |
| 4/7/2025 | GAMMA Investing LLC | 18,855 | $42K | 0.0% | +109.5% | 0.012% | |
| 2/25/2025 | Polar Asset Management Partners Inc. | 169,977 | $595K | 0.0% | -14.3% | 0.110% | |
| 2/17/2025 | UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 964,900 | $3.38M | 0.0% | N/A | 0.622% | |
| 2/17/2025 | Woodline Partners LP | 618,784 | $2.17M | 0.0% | N/A | 0.399% | |
| 2/17/2025 | Soleus Capital Management L.P. | 786,953 | $2.75M | 0.2% | -7.1% | 0.507% | |
| 2/17/2025 | Two Sigma Investments LP | 68,735 | $241K | 0.0% | -48.8% | 0.044% | |
| 2/17/2025 | Tema Etfs LLC | 890,548 | $3.12M | 1.3% | N/A | 0.574% | |
| 2/17/2025 | Polar Asset Management Partners Inc. | 169,977 | $595K | 0.0% | -14.3% | 0.110% | |
| 2/17/2025 | Janus Henderson Group PLC | 17,122,563 | $59.84M | 0.0% | +38.7% | 11.036% | |
| 2/17/2025 | Graham Capital Management L.P. | 22,189 | $78K | 0.0% | +74.7% | 0.014% | |
| 2/17/2025 | Clearline Capital LP | 3,217,894 | $11.26M | 1.5% | -0.8% | 2.074% | |
| 2/17/2025 | Cantor Fitzgerald L. P. | 225,000 | $788K | 0.0% | N/A | 0.145% | |
| 2/17/2025 | Ameriprise Financial Inc. | 94,456 | $331K | 0.0% | +187.9% | 0.061% | |
| 2/17/2025 | 683 Capital Management LLC | 4,550,000 | $15.93M | 1.0% | -6.2% | 2.933% | |
| 2/17/2025 | Acuta Capital Partners LLC | 779,308 | $2.73M | 2.7% | -38.2% | 0.502% | |
| 2/14/2025 | Schonfeld Strategic Advisors LLC | 493,900 | $1.73M | 0.0% | N/A | 0.318% | |
| 2/14/2025 | Virtus ETF Advisers LLC | 19,060 | $67K | 0.0% | N/A | 0.012% | |
| 2/14/2025 | Blue Owl Capital Holdings LP | 672,809 | $2.36M | 0.6% | -20.6% | 0.434% | |
| 2/14/2025 | Adage Capital Partners GP L.L.C. | 8,715,013 | $30.50M | 0.1% | -10.3% | 5.617% | |
| 2/14/2025 | Hsbc Holdings PLC | 13,577 | $47K | 0.0% | -52.5% | 0.009% | |
| 2/14/2025 | Rock Springs Capital Management LP | 9,599,170 | $33.60M | 1.3% | +0.7% | 6.187% | |
| 2/13/2025 | Marshall Wace LLP | 866,317 | $3.03M | 0.0% | -15.8% | 0.558% | |
| 2/13/2025 | Jump Financial LLC | 11,116 | $39K | 0.0% | N/A | 0.007% | |
| 2/13/2025 | Walleye Capital LLC | 129,629 | $454K | 0.0% | N/A | 0.084% | |
| 2/13/2025 | XTX Topco Ltd | 37,974 | $133K | 0.0% | N/A | 0.024% | |
| 2/13/2025 | Renaissance Technologies LLC | 1,189,471 | $4.16M | 0.0% | -8.9% | 0.767% | |
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| 2/12/2025 | NEOS Investment Management LLC | 824,603 | $2.89M | 0.1% | -1.3% | 0.531% | |
| 2/11/2025 | Sheets Smith Investment Management | 16,890 | $59K | 0.1% | N/A | 0.011% | |
| 2/10/2025 | Tejara Capital Ltd | 2,317,085 | $8.11M | 5.2% | -18.1% | 1.493% | |
| 2/4/2025 | HealthInvest Partners AB | 390,000 | $1.37M | 0.6% | +95.0% | 0.251% | |
| 1/28/2025 | Newbridge Financial Services Group Inc. | 10,700 | $37K | 0.0% | N/A | 0.007% | |
| 1/24/2025 | Golden State Equity Partners | 22,600 | $79K | 0.0% | +247.7% | 0.015% | |
| 1/22/2025 | PFG Investments LLC | 39,433 | $138K | 0.0% | +132.0% | 0.025% | |
| 1/15/2025 | Avanza Fonder AB | 19,600 | $69K | 0.0% | N/A | 0.013% | |
| 11/15/2024 | Frazier Life Sciences Management L.P. | 5,097,779 | $20.95M | 0.8% | +15.8% | 3.635% | |
| 11/15/2024 | State Street Corp | 47,561 | $195K | 0.0% | N/A | 0.034% | |
| 11/15/2024 | Polar Asset Management Partners Inc. | 198,300 | $815K | 0.0% | +36.0% | 0.141% | |
| 11/15/2024 | Janus Henderson Group PLC | 12,345,866 | $50.87M | 0.0% | +56.7% | 8.802% | |
| 11/15/2024 | Clearline Capital LP | 3,244,334 | $13.33M | 0.6% | -2.5% | 2.313% | |
| 11/14/2024 | Fred Alger Management LLC | 102,582 | $422K | 0.0% | +108.1% | 0.073% | |
| 11/14/2024 | Verition Fund Management LLC | 110,004 | $452K | 0.0% | -51.4% | 0.078% | |
| 11/14/2024 | Acuta Capital Partners LLC | 1,260,700 | $5.18M | 4.2% | +86.2% | 0.899% | |
| 11/12/2024 | HealthInvest Partners AB | 200,000 | $822K | 0.4% | N/A | 0.143% | |
| 11/5/2024 | GSA Capital Partners LLP | 67,069 | $276K | 0.0% | N/A | 0.048% | |
| 10/7/2024 | GAMMA Investing LLC | 10,693 | $44K | 0.0% | +58.1% | 0.008% | |
| 8/16/2024 | Perceptive Advisors LLC | 1,253,250 | $4.51M | 0.1% | N/A | 0.894% | |
| 8/16/2024 | Forefront Analytics LLC | 36,231 | $130K | 0.1% | -17.3% | 0.026% | |
| 8/16/2024 | Frazier Life Sciences Management L.P. | 4,401,371 | $15.85M | 0.7% | N/A | 3.138% | |
| 8/15/2024 | Blue Owl Capital Holdings LP | 897,809 | $3.23M | 0.9% | N/A | 0.640% | |
| 8/15/2024 | The Manufacturers Life Insurance Company | 14,621 | $53K | 0.0% | -87.7% | 0.010% | |
| 8/15/2024 | Millennium Management LLC | 3,201,705 | $11.53M | 0.0% | +46.9% | 2.283% | |
| 8/15/2024 | Deerfield Management Company L.P. Series C | 6,710,429 | $24.16M | 0.4% | N/A | 4.784% | |
| 8/14/2024 | Fred Alger Management LLC | 49,304 | $177K | 0.0% | -74.7% | 0.035% | |
| 8/14/2024 | Marshall Wace LLP | 1,144,051 | $4.12M | 0.0% | N/A | 0.816% | |
| 8/14/2024 | Integral Health Asset Management LLC | 1,775,000 | $6.39M | 0.6% | +86.8% | 1.266% | |
| 8/13/2024 | Rubric Capital Management LP | 15,307,347 | $55.11M | 1.4% | +12.9% | 10.914% | |
| 8/9/2024 | Renaissance Technologies LLC | 1,762,003 | $6.34M | 0.0% | +5.4% | 1.256% | |
| 8/7/2024 | Monaco Asset Management SAM | 348,128 | $1.25M | 0.2% | -14.0% | 0.248% | |
| 8/7/2024 | PFG Investments LLC | 17,000 | $61K | 0.0% | -45.5% | 0.012% | |
| 8/1/2024 | Rhumbline Advisers | 6,958 | $25K | 0.0% | +70.9% | 0.005% | |
| 5/16/2024 | Janus Henderson Group PLC | 5,120,573 | $16.95M | 0.0% | N/A | 3.651% | |
| 5/16/2024 | Knoll Capital Management LLC | 260,470 | $860K | 0.5% | +62.3% | 0.186% | |
| 5/15/2024 | Price T Rowe Associates Inc. MD | 991,971 | $3.27M | 0.0% | N/A | 0.707% | |
| 5/13/2024 | Index Fund Advisors Inc. | 30,000 | $99K | 0.0% | N/A | 0.021% | |
| 5/9/2024 | Monaco Asset Management SAM | 405,000 | $1.34M | 0.4% | -40.1% | 0.324% | |
| 5/8/2024 | Advisors Preferred LLC | 8,262 | $28K | 0.0% | N/A | 0.007% | |
| 5/7/2024 | SG Americas Securities LLC | 16,221 | $54K | 0.0% | N/A | 0.013% | |
| 5/1/2024 | BNP Paribas Financial Markets | 17,435 | $58K | 0.0% | +581,066.7% | 0.014% | |
| 2/15/2024 | Forefront Analytics LLC | 36,124 | $83K | 0.0% | -45.0% | 0.029% | |
| 2/14/2024 | Rubric Capital Management LP | 13,552,997 | $31.31M | 0.6% | +16.7% | 10.843% | |
| 2/13/2024 | NEOS Investment Management LLC | 351,905 | $813K | 0.1% | +751.5% | 0.282% | |
| 2/9/2024 | Primecap Management Co. CA | 54,000 | $125K | 0.0% | -31.6% | 0.043% | |
| 2/7/2024 | Monaco Asset Management SAM | 676,494 | $1.56M | 0.5% | +13.6% | 0.541% | |
| 2/2/2024 | Golden State Equity Partners | 20,300 | $47K | 0.0% | +41.0% | 0.016% | |
| 1/31/2024 | abrdn plc | 1,551,082 | $3.58M | 0.0% | N/A | 1.241% | |
| 1/18/2024 | Clear Harbor Asset Management LLC | 59,754 | $138K | 0.0% | -6.3% | 0.048% | |
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| 11/15/2023 | Tejara Capital Ltd | 3,215,001 | $4.15M | 2.4% | +5.8% | 2.572% | |
| 11/15/2023 | Rock Springs Capital Management LP | 7,676,481 | $9.90M | 0.3% | +9.0% | 6.142% | |
| 11/15/2023 | Adage Capital Partners GP L.L.C. | 800,000 | $1.03M | 0.0% | N/A | 0.640% | |
| 11/14/2023 | 683 Capital Management LLC | 6,000,000 | $7.74M | 0.6% | +11.1% | 4.800% | |
| 11/14/2023 | Primecap Management Co. CA | 79,000 | $102K | 0.0% | -49.9% | 0.063% | |
| 11/13/2023 | Tejara Capital Ltd | 3,215,001 | $4.15M | 3.1% | +5.8% | 2.572% | |
| 11/9/2023 | Formidable Asset Management LLC | 331,914 | $428K | 0.1% | N/A | 0.266% | |
| 11/8/2023 | Forefront Analytics LLC | 65,649 | $85K | 0.0% | -20.7% | 0.053% | |
| 11/7/2023 | Monaco Asset Management SAM | 595,729 | $768K | 0.2% | -15.6% | 0.477% | |
| 11/6/2023 | Privium Fund Management UK Ltd | 24,726 | $32K | 0.0% | -86.0% | 0.020% | |
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