Knott David M Jr Top Holdings and 13F Report (2026) About Knott David M JrInvestment ActivityKnott David M Jr has $182.84 million in total holdings as of September 30, 2026.Knott David M Jr owns shares of 80 different stocks, but just 16 companies or ETFs make up 80% of its holdings.Approximately 4.90% of the portfolio was purchased this quarter.About 16.36% of the portfolio was sold this quarter.This quarter, Knott David M Jr has purchased 84 new stocks and bought additional shares in 12 stocks.Knott David M Jr sold shares of 18 stocks and completely divested from 12 stocks this quarter.Largest Holdings Alphabet $31,150,451Apollo Global Management $26,113,500Iovance Biotherapeutics $17,265,300Xeris Biopharma $9,587,724Syndax Pharmaceuticals $8,051,927 Largest New Holdings this Quarter 687604108 - Oruka Therapeutics, Inc. $916,190 Holding19459J104 - Collegium Pharmaceutical $850,980 Holding26818M108 - Dyne Therapeutics, Inc. $837,720 Holding26614N102 - DuPont de Nemours $489,296 Holding28036F105 - Edgewise Therapeutics $426,381 Holding Largest Purchases this Quarter Enliven Therapeutics 22,721 shares (about $1.04M)Oruka Therapeutics, Inc. 11,000 shares (about $916.19K)Collegium Pharmaceutical 39,000 shares (about $850.98K)Dyne Therapeutics, Inc. 52,000 shares (about $837.72K)Cogent Biosciences 25,000 shares (about $800.50K) Largest Sales this Quarter Iovance Biotherapeutics 435,000 shares (about $6.45M)Protagonist Therapeutics 30,277 shares (about $4.27M)Agios Pharmaceuticals 46,000 shares (about $1.53M)Travere Therapeutics 17,315 shares (about $1.02M)Rezolute 210,362 shares (about $870.90K) Sector Allocation Over TimeMap of 500 Largest Holdings ofKnott David M Jr Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorGOOGAlphabet$31,150,4510.0%91,42017.0%Communication ServicesAPOApollo Global Management$26,113,5000.0%225,00014.3%FinanceIOVAIovance Biotherapeutics$17,265,300$6,446,700 ▼-27.2%1,165,0009.4%HealthcareXERSXeris Biopharma$9,587,724$545,876 ▼-5.4%1,002,9005.2%HealthcareSNDXSyndax Pharmaceuticals$8,051,927$168,279 ▼-2.0%428,2944.4%HealthcareTVTXTravere Therapeutics$7,652,457$1,019,507 ▼-11.8%129,9674.2%HealthcareBBIOBridgeBio Pharma$6,580,000$470,470 ▲7.7%100,0003.6%HealthcareJPMJPMorgan Chase & Co.$5,759,419$227,942 ▼-3.8%17,4093.2%FinanceLPL Financial Holdings Inc.$5,045,7000.0%16,5002.8%CommonJAAAJanus Henderson AAA CLO ETF$4,720,3580.0%93,5282.6%ETFALKSAlkermes$4,637,879$295,796 ▼-6.0%114,4592.5%HealthcarePTGXProtagonist Therapeutics$4,610,343$4,265,726 ▼-48.1%32,7232.5%HealthcareCybin Inc$4,547,3000.0%370,0002.5%CommonCOGTCogent Biosciences$4,357,314$800,500 ▲22.5%136,0812.4%HealthcareVRDNViridian Therapeutics$3,932,690$205,900 ▲5.5%191,0002.2%HealthcareTGTXTG Therapeutics$3,337,819$390,460 ▼-10.5%59,8391.8%HealthcareRCUSArcus Biosciences$2,589,225$490,770 ▲23.4%100,2411.4%HealthcareMDGLMadrigal Pharmaceuticals$1,814,256$302,376 ▲20.0%3,6001.0%HealthcareRLMDRelmada Therapeutics$1,809,600$109,330 ▲6.4%480,0001.0%HealthcareXBISPDR S&P Biotech ETF$1,734,480$630,720 ▼-26.7%11,0000.9%ETFABAllianceBernstein$1,674,2400.0%48,0000.9%FinanceAGIOAgios Pharmaceuticals$1,631,178$1,529,500 ▼-48.4%49,0580.9%HealthcareOBIOOrchestra BioMed$1,577,7090.0%253,6510.9%HealthcareCGEMCullinan Therapeutics$1,463,914$401,970 ▲37.9%95,3690.8%HealthcareCDNACareDx$1,440,725$554,775 ▲62.6%22,1650.8%HealthcareELVNEnliven Therapeutics$1,324,959$1,041,530 ▲367.5%28,9040.7%HealthcareSpruce Biosciences, Inc.$1,267,209$295,609 ▲30.4%26,0850.7%CommonCLOZEldridge BBB-B CLO ETF$1,257,3240.0%47,8070.7%ETFDCGODocGo$1,067,8060.0%2,670,8500.6%HealthcarePFEPfizer$922,2510.0%32,3370.5%HealthcareOruka Therapeutics, Inc.$916,190$916,190 ▲New Holding11,0000.5%CommonCOLLCollegium Pharmaceutical$850,980$850,980 ▲New Holding39,0000.5%HealthcareDyne Therapeutics, Inc.$837,720$837,720 ▲New Holding52,0000.5%CommonAAPLApple$830,5520.0%2,4940.5%TechnologyMSFTMicrosoft$820,6400.0%1,6000.4%TechnologyJNJJohnson & Johnson$773,570$529,480 ▼-40.6%2,9220.4%HealthcareRZLTRezolute$660,901$870,898 ▼-56.9%159,6380.4%HealthcareCNQCanadian Natural Resources$655,120$135,656 ▼-17.2%13,9180.4%EnergyLB Pharmaceuticals, Inc.$654,955$157,358 ▲31.6%17,0650.4%CommonIBBiShares Biotechnology ETF$526,325$631,590 ▼-54.5%2,5000.3%ETFSLDBSolid Biosciences$514,263$107,879 ▲26.5%71,1290.3%HealthcareDDDuPont de Nemours$489,296$489,296 ▲New Holding3,7670.3%IndustrialsIBMInternational Business Machines$471,0900.0%2,1420.3%TechnologyConnect Biopharma Holdings Limited$461,853$27,496 ▼-5.6%419,8660.3%CommonBIIBBiogen$451,760$451,760 ▼-50.0%2,0000.2%HealthcareEWTXEdgewise Therapeutics$426,381$426,381 ▲New Holding10,5020.2%HealthcarePelthos Therapeutics, Inc.$370,700$93,053 ▼-20.1%17,6440.2%CommonNVDANVIDIA$292,3260.0%1,2800.2%TechnologyRHPRyman Hospitality Properties$286,8720.0%2,4000.2%Real EstateINSMInsmed$257,157$228,280 ▼-47.0%2,2530.1%HealthcareMLYSMineralys Therapeutics$251,300$251,300 ▲New Holding10,0000.1%HealthcareAVGOBroadcom$249,3450.0%7100.1%TechnologyKimberly-Clark Corporation$233,8320.0%2,4000.1%CommonMDLZMondelez International$173,4600.0%3,0000.1%Consumer StaplesNVCTNuvectis Pharma$143,130$143,130 ▲New Holding6,7770.1%HealthcareLEGHLegacy Housing$114,6800.0%4,0000.1%Consumer DiscretionaryPWRQuanta Services$113,0820.0%1760.1%IndustrialsEBCEastern Bankshares$104,6500.0%5,0000.1%FinanceGOOGLAlphabet$103,2240.0%3000.1%Communication ServicesAbivax$99,020$99,020 ▲New Holding1,0000.1%CommonIWPiShares Russell Mid-Cap Growth ETF$95,6880.0%6950.1%ETFCTVACorteva$93,6460.0%1,2060.1%MaterialsIVVDInvivyd$87,0100.0%100,0000.0%HealthcareRain Enhancement Technologies Holdco Inc$81,3490.0%101,6860.0%CommonURIUnited Rentals$78,0610.0%780.0%IndustrialsAMZNAmazon.com$74,7450.0%3000.0%Consumer DiscretionaryDHRDanaher$39,8790.0%1800.0%HealthcareDOWDOW$33,2130.0%1,2060.0%MaterialsFSKFS KKR Capital$31,5960.0%2,8750.0%FinanceTMOThermo Fisher Scientific$30,3770.0%450.0%HealthcareOXYOccidental Petroleum$25,9450.0%4690.0%EnergyBrightstar Lottery PLC$24,9750.0%2,5000.0%CommonBXBlackstone$23,5390.0%2100.0%FinanceUNHUnitedHealth Group$20,9240.0%570.0%HealthcareCRMSalesforce$17,6770.0%770.0%TechnologySTWDStarwood Property Trust$5,4000.0%4000.0%FinanceKDKyndryl$4,8190.0%4280.0%TechnologyOccidential Pertro Wts exp. 8/3/27$4,2680.0%1940.0%CommonGEHCGE HealthCare Technologies$3,2680.0%500.0%HealthcareWABWabtec$1,7230.0%60.0%IndustrialsCLSTCatalyst Bancorp$0$3,583,020 ▼-100.0%00.0%FinanceATRCAtriCure$0$1,438,172 ▼-100.0%00.0%HealthcareARDXArdelyx$0$1,342,157 ▼-100.0%00.0%HealthcareRAREUltragenyx Pharmaceutical$0$1,271,124 ▼-100.0%00.0%HealthcareVERAVera Therapeutics$0$1,115,660 ▼-100.0%00.0%HealthcareVSTMVerastem$0$592,100 ▼-100.0%00.0%HealthcareKURAKura Oncology$0$578,854 ▼-100.0%00.0%HealthcareDuPont de Nemours, Inc.$0$510,956 ▼-100.0%00.0%CommonQ32 Bio Inc$0$387,449 ▼-100.0%00.0%CommonBSXBoston Scientific$0$256,080 ▼-100.0%00.0%HealthcareWVEWAVE Life Sciences$0$232,400 ▼-100.0%00.0%HealthcareBMYBristol Myers Squibb$0$115,240 ▼-100.0%00.0%HealthcareShowing largest 100 holdings. 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