Knott David M Jr Top Holdings and 13F Report (2026)

About Knott David M Jr

Investment Activity

Knott David M Jr has $168.03 million in total holdings as of March 31, 2026.
Knott David M Jr owns shares of 86 different stocks, but just 21 companies or ETFs make up 80% of its holdings.
Approximately 15.69% of the portfolio was purchased this quarter.
About 34.97% of the portfolio was sold this quarter.
This quarter, Knott David M Jr has purchased 88 new stocks and bought additional shares in 18 stocks.
Knott David M Jr sold shares of 13 stocks and completely divested from 12 stocks this quarter.

Largest Holdings

Alphabet: $26,228,398
Apollo Global Management: $25,069,500
Syndax Pharmaceuticals: $9,857,920
BridgeBio Pharma: $6,683,400
Protagonist Therapeutics: $6,640,200

Largest New Holdings this Quarter

462260100 - Iovance Biotherapeutics: $5,616,000 Holding
52012V100 - LPL Financial Holdings Inc.: $4,963,695 Holding
75955J402 - Relmada Therapeutics: $3,057,528 Holding
039697107 - Ardelyx: $1,239,930 Holding
92337C203 - Verastem: $551,200 Holding

Largest Purchases this Quarter

Iovance Biotherapeutics: 1,600,000 shares (about $5.62M)
LPL Financial Holdings Inc.: 16,500 shares (about $4.96M)
Relmada Therapeutics: 439,300 shares (about $3.06M)
Agios Pharmaceuticals: 75,058 shares (about $2.54M)
TG Therapeutics: 45,001 shares (about $1.49M)

Largest Sales this Quarter

Catalyst Pharmaceuticals: 69,000 shares (about $1.71M)
Travere Therapeutics: 45,367 shares (about $1.35M)
Protagonist Therapeutics: 10,000 shares (about $1.05M)
Arcus Biosciences: 40,000 shares (about $864.00K)
Solid Biosciences: 115,297 shares (about $830.14K)

Sector Allocation Over Time

Selling

Neutral

Buying

Latest 13F Holdings and Changes Since Previous Quarterly Filing

Issuer Name	Holdings Value	Approximate Purchase/Sale	Change in Shares	Shares Held	% of Portfolio	Sector
GOOG Alphabet	$26,228,398		0.0%	91,420	15.6%	Computer and Technology
APO Apollo Global Management	$25,069,500		0.0%	225,000	14.9%	Finance
SNDX Syndax Pharmaceuticals	$9,857,920	$163,520 â–²	1.7%	422,000	5.9%	Medical
BBIO BridgeBio Pharma	$6,683,400	$371,300 â–²	5.9%	90,000	4.0%	Medical
PTGX Protagonist Therapeutics	$6,640,200	$1,054,000 â–¼	-13.7%	63,000	4.0%	Medical
XERS Xeris Biopharma	$6,148,000	$522,000 â–²	9.3%	1,060,000	3.7%	Medical
JPM JPMorgan Chase & Co.	$5,729,354		0.0%	19,477	3.4%	Finance
IOVA Iovance Biotherapeutics	$5,616,000	$5,616,000 â–²	New Holding	1,600,000	3.3%	Medical
LPL Financial Holdings Inc.	$4,963,695	$4,963,695 â–²	New Holding	16,500	3.0%	Common
JAAA Janus Henderson AAA CLO ETF	$4,711,005		0.0%	93,528	2.8%	ETF
ALKS Alkermes	$4,243,200	$884,000 â–²	26.3%	120,000	2.5%	Medical
TVTX Travere Therapeutics	$4,178,206	$1,347,853 â–¼	-24.4%	140,633	2.5%	Medical
COGT Cogent Biosciences	$4,002,960	$76,980 â–²	2.0%	104,000	2.4%	Medical
VRDN Viridian Therapeutics	$3,540,360	$704,160 â–²	24.8%	181,000	2.1%	Medical
AGIO Agios Pharmaceuticals	$3,148,152	$2,539,212 â–²	417.0%	93,058	1.9%	Medical
RLMD Relmada Therapeutics	$3,057,528	$3,057,528 â–²	New Holding	439,300	1.8%	Medical
TGTX TG Therapeutics	$2,989,833	$1,494,933 â–²	100.0%	90,001	1.8%	Medical
CPRX Catalyst Pharmaceuticals	$2,971,200	$1,708,440 â–¼	-36.5%	120,000	1.8%	Medical
ACLX Arcellx	$2,231,297	$719,577 â–¼	-24.4%	19,433	1.3%	Medical
XBI SPDR S&P Biotech ETF	$1,916,100	$255,480 â–²	15.4%	15,000	1.1%	ETF
AB AllianceBernstein	$1,797,120		0.0%	48,000	1.1%	Finance
RCUS Arcus Biosciences	$1,754,806	$864,000 â–¼	-33.0%	81,241	1.0%	Medical
DCGO DocGo	$1,680,232		0.0%	2,670,850	1.0%	Medical
Cybin Inc	$1,680,000	$311,126 â–²	22.7%	350,000	1.0%	Common
CYTK Cytokinetics	$1,558,376	$682,564 â–¼	-30.5%	23,644	0.9%	Medical
CNTA Centessa Pharmaceuticals	$1,549,080	$1,390,200 â–²	875.0%	39,000	0.9%	Medical
ATRC AtriCure	$1,466,442		0.0%	51,400	0.9%	Medical
ARDX Ardelyx	$1,239,930	$1,239,930 â–²	New Holding	207,000	0.7%	Medical
CLOZ Eldridge BBB-B CLO ETF	$1,226,250		0.0%	47,807	0.7%	ETF
JNJ Johnson & Johnson	$1,203,134	$488,880 â–¼	-28.9%	4,922	0.7%	Medical
RZLT Rezolute	$1,128,500	$91,500 â–²	8.8%	370,000	0.7%	Medical
OBIO Orchestra BioMed	$1,078,017	$15,517 â–²	1.5%	253,651	0.6%	Medical
MDGL Madrigal Pharmaceuticals	$1,046,940		0.0%	2,000	0.6%	Medical
VERA Vera Therapeutics	$1,045,980		0.0%	26,000	0.6%	Medical
Connect Biopharma Holdings Limited	$1,016,128	$492,128 â–²	93.9%	387,835	0.6%	Common
IBB iShares Biotechnology ETF	$928,675		0.0%	5,500	0.6%	Finance
PFE Pfizer	$908,023		0.0%	32,337	0.5%	Medical
BMY Bristol Myers Squibb	$826,174	$508,126 â–¼	-38.1%	13,622	0.5%	Medical
CNQ Canadian Natural Resources	$818,664		0.0%	16,800	0.5%	Energy
BIIB Biogen	$733,320	$366,660 â–¼	-33.3%	4,000	0.4%	Medical
RARE Ultragenyx Pharmaceutical	$692,796	$273,670 â–²	65.3%	33,069	0.4%	Medical
AAPL Apple	$632,952		0.0%	2,494	0.4%	Computer and Technology
MSFT Microsoft	$592,272		0.0%	1,600	0.4%	Computer and Technology
VSTM Verastem	$551,200	$551,200 â–²	New Holding	104,000	0.3%	Medical
ADMA ADMA Biologics	$542,402		0.0%	60,200	0.3%	Medical
IBM International Business Machines	$519,285		0.0%	2,142	0.3%	Computer and Technology
Biohaven Pharmaceutical Holding Co. Ltd	$513,691	$513,691 â–²	New Holding	60,720	0.3%	Common
Pelthos Therapeutics, Inc.	$442,744	$37,650 â–²	9.3%	21,073	0.3%	Common
KURA Kura Oncology	$428,996	$110,227 â–²	34.6%	52,767	0.3%	Medical
EOLS Evolus	$408,279		0.0%	99,338	0.2%	Medical
CGEM Cullinan Therapeutics	$343,882	$343,882 â–²	New Holding	24,200	0.2%	Medical
SLDB Solid Biosciences	$339,430	$830,139 â–¼	-71.0%	47,143	0.2%	Medical
LENZ Therapeutics, Inc.	$308,648	$183,000 â–¼	-37.2%	33,732	0.2%	Common
WVE WAVE Life Sciences	$290,000	$362,500 â–¼	-55.6%	40,000	0.2%	Medical
Rain Enhancement Technologies Holdco Inc	$258,282	$258,282 â–²	New Holding	101,686	0.2%	Common
Kimberly-Clark Corporation	$231,528		0.0%	2,400	0.1%	Common
NVDA NVIDIA	$223,290		0.0%	1,280	0.1%	Computer and Technology
RHP Ryman Hospitality Properties	$221,448		0.0%	2,400	0.1%	Finance
AVGO Broadcom	$219,859		0.0%	710	0.1%	Computer and Technology
MDLZ Mondelez International	$172,920		0.0%	3,000	0.1%	Consumer Staples
DD DuPont de Nemours	$172,529		0.0%	3,767	0.1%	Basic Materials
Jasper Therapeutics, Inc.	$140,883	$18,050 â–¼	-11.4%	160,789	0.1%	Common
IVVD Invivyd	$130,000		0.0%	100,000	0.1%	Medical
CTVA Corteva	$100,954		0.0%	1,206	0.1%	Consumer Staples
MREO Mereo BioPharma Group	$99,111		0.0%	300,337	0.1%	Medical
EBC Eastern Bankshares	$97,800		0.0%	5,000	0.1%	Finance
PWR Quanta Services	$96,628		0.0%	176	0.1%	Construction
IWP iShares Russell Mid-Cap Growth ETF	$89,043		0.0%	695	0.1%	ETF
GOOGL Alphabet	$86,268		0.0%	300	0.1%	Computer and Technology
LEGH Legacy Housing	$81,720		0.0%	4,000	0.0%	Finance
AMZN Amazon.com	$62,493		0.0%	300	0.0%	Retail/Wholesale
URI United Rentals	$56,828		0.0%	78	0.0%	Construction
DOW DOW	$50,230		0.0%	1,206	0.0%	Basic Materials
DHR Danaher	$34,128		0.0%	180	0.0%	Medical
IGT International Game Technology	$31,850	$31,850 â–²	New Holding	2,500	0.0%	Consumer Discretionary
OXY Occidental Petroleum	$30,462	$17,862 â–²	141.8%	469	0.0%	Energy
FS KKR Capital Corp.	$29,267	$29,267 â–²	New Holding	2,875	0.0%	Common
BX Blackstone	$24,148		0.0%	210	0.0%	Finance
TMO Thermo Fisher Scientific	$22,119		0.0%	45	0.0%	Medical
UNH UnitedHealth Group	$15,424		0.0%	57	0.0%	Medical
CRM Salesforce	$14,374		0.0%	77	0.0%	Computer and Technology
STWD Starwood Property Trust	$6,888		0.0%	400	0.0%	Finance
KD Kyndryl	$5,615		0.0%	428	0.0%	Business Services
OXY Occidental Petroleum	$4,268		0.0%	194	0.0%	Energy
GEHC GE HealthCare Technologies	$3,559		0.0%	50	0.0%	Medical
WAB Wabtec	$1,499		0.0%	6	0.0%	Transportation
Calumet, Inc.	$0	$44,011,434 â–¼	-100.0%	0	0.0%	Common
Tectonic Therapeutic, Inc.	$0	$1,543,640 â–¼	-100.0%	0	0.0%	Common
BHVN Biohaven	$0	$1,250,029 â–¼	-100.0%	0	0.0%	Medical
Nektar Therapeutics	$0	$655,340 â–¼	-100.0%	0	0.0%	Common
SRRK Scholar Rock	$0	$612,868 â–¼	-100.0%	0	0.0%	Medical
XENE Xenon Pharmaceuticals	$0	$491,317 â–¼	-100.0%	0	0.0%	Medical
FATE Fate Therapeutics	$0	$358,649 â–¼	-100.0%	0	0.0%	Medical
Mersana Therapeutics, Inc.	$0	$289,300 â–¼	-100.0%	0	0.0%	Common
DAWN Day One Biopharmaceuticals	$0	$241,239 â–¼	-100.0%	0	0.0%	Medical
QURE uniQure	$0	$95,720 â–¼	-100.0%	0	0.0%	Medical
FSK FS KKR Capital	$0	$42,579 â–¼	-100.0%	0	0.0%	Finance
International Game Technology PLC	$0	$38,700 â–¼	-100.0%	0	0.0%	Common

Showing largest 100 holdings. View all holdings.

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Knott David M Jr Top Holdings and 13F Report (2026)

About Knott David M Jr

Investment Activity

Largest Holdings

Largest New Holdings this Quarter

Largest Purchases this Quarter

Largest Sales this Quarter

Sector Allocation Over Time

Latest 13F Holdings and Changes Since Previous Quarterly Filing

More Institutional Buying and Selling Information

Best-in-Class Portfolio Monitoring

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Advanced Stock Screeners and Research Tools

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Knott David M Jr Top Holdings and 13F Report (2026)

About Knott David M Jr

Investment Activity

Largest Holdings

Largest New Holdings this Quarter

Largest Purchases this Quarter

Largest Sales this Quarter

Sector Allocation Over Time

Map of 500 Largest Holdings ofKnott David M Jr

Latest 13F Holdings and Changes Since Previous Quarterly Filing

More Institutional Buying and Selling Information

MarketBeat All Access Features

Best-in-Class Portfolio Monitoring

Stock Ideas and Recommendations

Advanced Stock Screeners and Research Tools