NYSEARCA:SBIO ALPS Medical Breakthroughs ETF (SBIO) Price, Holdings, & News $66.83 -0.26 (-0.39%) As of 03:58 PM Eastern Add Compare Share Share Stock Analysis Stock AnalysisChartHoldingsNews and TrendsOwnershipRatingsShort Interest About ALPS Medical Breakthroughs ETF (NYSEARCA:SBIO) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get SBIO alerts:Sign Up Key Stats Today's Range$65.65▼$66.8350-Day Range$58.66▼$70.7952-Week Range$34.66▼$70.85Volume36,902 shsAverage Volume37,864 shsMarket Capitalization$211.85 millionAssets Under Management$241.22 millionDividend YieldN/ANet Expense Ratio0.50%Aggregate RatingModerate Buy ETF Overview The ALPS Medical Breakthroughs ETF (SBIO) is an exchange-traded fund that is based on the S-Network Medical Breakthroughs index. The fund tracks, a market-cap weighted index comprising US-listed biotech companies with one or more drugs currently in either Phase II or Phase III FDA clinical trials. SBIO was launched on Dec 31, 2014 and is managed by ALPS. Read More ALPS Medical Breakthroughs ETF ExpensesTypeSBIOHealth Care ETFsEquity ETFsNYSEARCA ETFsAll ETFsManagement Fee0.50%0.55%0.57%0.51%0.53%Other Expenses0.00%0.52%0.53%0.60%0.54%Total Expense0.50%0.76%0.75%0.75%0.73%Fee Waiver0.00%-0.85%-0.67%-0.77%-0.68%Net Expense0.50%0.58%0.63%0.57%0.60% Receive SBIO Stock News and Ratings via Email Sign-up to receive the latest news and ratings for ALPS Medical Breakthroughs ETF and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsSMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. 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SBIO ETF News Headlines(SBIO) ALPS Medical Breakthroughs ETFAugust 29 at 11:39 PM | sa.investing.comSBIO: Dividendenhistorie, Rendite und Ex-Dividenden-TagAugust 22, 2026 | de.investing.comLouis Navellier: My #1 AI stock for 2026 (name & ticker inside)Louis Navellier's Stock Grader system helped him flag Nvidia before its 82,000% run and has identified the top S&P 500 stock for 12 years running—and today, he's giving away his #1 AI stock pick for 2026, free. This company's sales are up 28% year over year, it holds over 30,000 patents in wireless and video technology, and it just earned an A-rating in his proprietary Stock Grader system that has cost him $9 million to build and maintain.August 31 at 1:00 AM | InvestorPlace (Ad)SBIO: Biotech Breakthrough Opportunities Screened For Cash BurnJuly 7, 2026 | seekingalpha.comCREATOR TV SPORTS™ UNVEILS CREATOR LINEUP FOR INAUGURAL "CREATOR PICKLEBALL TOUR" AT VIDCON ANAHEIMJune 15, 2026 | prnewswire.comSBIO: Leaning Into Drug Discovery And Medical BreakthroughsApril 28, 2026 | seekingalpha.comSee More Headlines SBIO ETF - Frequently Asked Questions How have SBIO shares performed this year? ALPS Medical Breakthroughs ETF's stock was trading at $51.22 on January 1st, 2026. Since then, SBIO shares have increased by 29.2% and is now trading at $66.20. Who are ALPS Medical Breakthroughs ETF's major shareholders? Top institutional investors of ALPS Medical Breakthroughs ETF include Fulcrum Equity Management (0.14%) and Harbor Investment Advisory LLC (0.02%). How do I buy shares of ALPS Medical Breakthroughs ETF? Shares of SBIO stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of ALPS Medical Breakthroughs ETF own? Based on aggregate information from My MarketBeat watchlists, some other companies that ALPS Medical Breakthroughs ETF investors own include Waste Connections (WCN), American Water Works (AWK), iShares Micro-Cap ETF (IWC), The RMR Group (RMR), AUO (AUOTY), DiamondRock Hospitality (DRH) and Triple Flag Precious Metals (TFPM). Fund Details IssuerALPS Fund NameALPS Medical Breakthroughs ETF Tax ClassificationRegulated Investment Company Stock ExchangeNYSEARCACurrent SymbolNYSEARCA:SBIO Inception Date12/30/2014 Fund ManagerRyan Mischker, Andrew Hicks WebN/A PhoneN/AFund Focus Asset ClassEquity BenchmarkS-Network Medical Breakthroughs Index CategorySector FocusHealth Care Development LevelDeveloped Markets RegionNorth America Number of Holdings109 Fund Statistics Assets Under Management$241.22 million Average Daily Volume$39.20 thousand Discount/Premium0.08% Administrator, Advisor and Custodian AdministratorALPS Fund Services, Inc. AdvisorALPS Advisors, Inc. CustodianState Street Bank and Trust Company DistributorALPS Distributors, Inc. Transfer AgentState Street Bank and Trust Company TrusteeN/A Lead Market MakerGTS Options OptionableOptionable Options Volume1 Put Options0 Call Options1 Short Interest78,401 shs Miscellaneous Outstanding Shares3,170,000Beta0.74 Creation Unit50,000 Creation Fee$500.00 7 Stocks That Will Be Magnificent in 2026Discover the next wave of investment opportunities with our report, 7 Stocks That Will Be Magnificent in 2026. Explore companies poised to replicate the growth, innovation, and value creation of the tech giants dominating today's markets.Get This Free Report Top 10 SBIO HoldingsCrinetics Pharmaceuticals (NASDAQ:CRNX)Holding Weight: 4.55%Apogee Therapeutics (NASDAQ:APGE)Holding Weight: 4.24%Oruka Therapeutics (NASDAQ:ORKA)Holding Weight: 3.41%CG Oncology (NASDAQ:CGON)Holding Weight: 3.37%Dianthus Therapeutics (NASDAQ:DNTH)Holding Weight: 3.23%Xenon Pharmaceuticals (NASDAQ:XENE)Holding Weight: 3.07%Travere Therapeutics (NASDAQ:TVTX)Holding Weight: 2.94%ACADIA Pharmaceuticals (NASDAQ:ACAD)Holding Weight: 2.46%Edgewise Therapeutics (NASDAQ:EWTX)Holding Weight: 2.42%Veradermics (NYSE:MANE)Holding Weight: 2.39%Full Holdings DetailsSBIO Sector ExposureSBIO Industry Exposure This page (NYSEARCA:SBIO) was last updated on 8/31/2026 by MarketBeat.com Staff. 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