SPDR S&P Biotech ETF (XBI) Holdings $82.95 +1.07 (+1.31%) As of 04:10 PM Eastern Add Compare Share Share Holdings Stock AnalysisChartDividendHeadlinesHoldingsOwnershipRatingsBuy This Stock Top 50 XBI HoldingsRankCompanyCurrent PriceWeightShares Held1NTRANatera$150.66-2.7%2.82%903,6192VRTXVertex Pharmaceuticals$505.96+0.5%2.71%263,5463INSMInsmed$72.01+0.9%2.70%1,763,5604ALNYAlnylam Pharmaceuticals$260.50+1.3%2.66%538,6265NBIXNeurocrine Biosciences$106.86-0.4%2.55%1,197,1846UTHRUnited Therapeutics$294.81-2.0%2.55%425,2367GILDGilead Sciences$105.71+1.4%2.52%1,145,4558EXASExact Sciences$45.21+0.9%2.47%2,817,1569AMGNAmgen$289.63+0.4%2.44%417,85910INCYIncyte$61.91+2.4%2.36%1,927,814 Get the Latest News and Ratings for XBI and Related StocksEnter your email address below to receive the latest news and analysts' ratings for SPDR S&P Biotech ETF and its competitors with MarketBeat's FREE daily newsletter. 11BIIBBiogen$120.64+0.4%2.33%931,43912MDGLMadrigal Pharmaceuticals$339.49-0.4%2.29%361,27113ABBVAbbVie$193.14-0.2%2.24%615,69714REGNRegeneron Pharmaceuticals$593.89+4.4%2.24%189,37215BPMCBlueprint Medicines$89.94+1.7%2.14%1,199,85416EXELExelixis$38.78+0.6%2.12%2,780,68917BMRNBioMarin Pharmaceutical$63.23-0.1%1.97%1,581,91518MRNAModerna$28.24+1.5%1.94%3,729,62419TGTXTG Therapeutics$45.02+2.6%1.77%2,196,99820BBIOBridgeBio Pharma$37.87+4.0%1.74%2,441,79321HALOHalozyme Therapeutics$60.92+0.2%1.66%1,342,27222RVMDRevolution Medicines$40.47-0.5%1.53%1,974,17223CYTKCytokinetics$43.12+4.4%1.48%1,781,72624SMMTSummit Therapeutics$24.25+2.7%1.44%2,775,36625CRSPCRISPR Therapeutics$38.46+2.8%1.40%1,764,11226SRPTSarepta Therapeutics$61.95+1.8%1.33%1,177,43127ROIVRoivant Sciences$11.62+2.9%1.28%5,988,83528IONSIonis Pharmaceuticals$30.57+2.5%1.27%2,129,14529ADMAADMA Biologics$23.89-0.9%1.21%2,698,03330VKTXViking Therapeutics$28.47+1.9%1.12%2,220,18131SWTXSpringWorks Therapeutics$46.220.0%1.07%1,340,04932KRYSKrystal Biotech$172.08+0.9%1.04%291,95533ALKSAlkermes$28.75-0.1%1.03%1,817,55434PCVXVaxcyte$36.12+3.9%1.03%1,592,35835RNAAvidity Biosciences$32.51+1.1%0.98%1,749,51936NUVLNuvalent$75.57-0.4%0.93%618,44337TWSTTwist Bioscience$38.04-4.1%0.93%1,199,35338ACLXArcellx$65.10+0.6%0.92%706,78639RYTMRhythm Pharmaceuticals$64.87-0.5%0.91%697,44240VCYTVeracyte$30.48-2.9%0.88%1,340,547"I'm risking my reputation on this" (Ad)I've discovered something so significant about the 2025 crypto market that I had to put everything else aside and write a book about it. 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Claim your FREE copy of my controversial book before I change my mind.41SRRKScholar Rock$32.84+0.2%0.87%1,349,02142RXRXRecursion Pharmaceuticals$5.60-2.1%0.84%7,229,29843APLSApellis Pharmaceuticals$18.62+2.3%0.83%2,176,13944SLNOSoleno Therapeutics$75.31+0.1%0.82%560,01145RAREUltragenyx Pharmaceutical$38.93+2.3%0.81%1,072,85946CRNXCrinetics Pharmaceuticals$33.54+0.7%0.79%1,233,71347ACADACADIA Pharmaceuticals$14.57+1.0%0.75%2,419,65548AKROAkero Therapeutics$45.26+5.2%0.71%894,91049PTCTPTC Therapeutics$50.03+1.0%0.69%689,43750AGIOAgios Pharmaceuticals$29.52+1.4%0.66%1,131,094 Geographic ExposureUnited States95.0%Bermuda1.3%Switzerland1.3%Ireland1.1%Virgin Islands, British0.6%Netherlands0.3%Canada0.1%Currency ExposureUSD100.0%Sector ExposureHealth Care98.4%Consumer Discretionary0.9%Biotechnology0.5%Industry ExposureBiotechnology91.5%Health Care Equipment & Supplies4.6%Health Care Providers & Services2.7%Distributors0.8%Diversified Consumer Services0.2%SubIndustry ExposureBiotechnology91.4%Life Sciences Tools & Services4.1%Health Care Services2.7%Pharmaceuticals0.7%Health Care Equipment0.4%Health Care Supplies0.1%Coupon Exposure4-60.1%Maturity Exposure5-100.1% Related Companies and Tools Related Companies IHI Portfolio Companies IBB Portfolio Companies IXJ Portfolio Companies IYH Portfolio Companies FHLC Portfolio Companies FBT Portfolio Companies RYH Portfolio Companies FXH Portfolio Companies RSPH Portfolio Companies IHF Portfolio Companies This page (NYSEARCA:XBI) was last updated on 4/30/2025 by MarketBeat.com Staff From Our PartnersDOGE officially begins retirement transformationElon Musk's Department of Government Efficiency ("DOGE") just announced the first-ever "fully digital retireme...Altimetry | SponsoredM.A.G.A. is Finished – This Could be even BetterYou’ve no doubt heard Trump’s rally cry: Make America Great Again. 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