SPDR S&P Biotech ETF (XBI) Holdings $89.85 -0.44 (-0.49%) Closing price 04:10 PM EasternExtended Trading$89.89 +0.04 (+0.04%) As of 07:33 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Holdings Stock AnalysisChartDividendHeadlinesHoldingsOwnershipRatingsShort InterestBuy This Stock Top 25 XBI HoldingsRankCompanyCurrent PriceWeightShares Held1ALNYAlnylam Pharmaceuticals$446.51-1.3%3.61%399,5452HALOHalozyme Therapeutics$73.15+0.5%3.06%2,215,3023INSMInsmed$136.10+0.8%3.06%1,217,5654INCYIncyte$84.61+1.1%2.92%1,732,7925UTHRUnited Therapeutics$304.76-0.8%2.67%431,4456REGNRegeneron Pharmaceuticals$580.70+0.2%2.60%230,0237GILDGilead Sciences$112.97+0.4%2.54%1,091,5588ABBVAbbVie$210.25+1.1%2.53%622,9759NBIXNeurocrine Biosciences$139.60+0.5%2.52%960,74010BIIBBiogen$132.22-0.3%2.46%896,533 Get the Latest News and Ratings for XBI and Related StocksEnter your email address below to receive the latest news and analysts' ratings for SPDR S&P Biotech ETF and its competitors with MarketBeat's FREE daily newsletter. 11AMGNAmgen$287.71+0.7%2.38%408,76012MRNAModerna$24.09-1.6%2.37%4,298,96213BMRNBioMarin Pharmaceutical$58.27+1.0%2.36%2,087,08614BBIOBridgeBio Pharma$51.76-1.5%2.36%2,442,14015MDGLMadrigal Pharmaceuticals$437.85+0.2%2.28%304,61016NTRANatera$168.25+0.2%2.26%715,41317EXELExelixis$37.42-1.3%2.13%2,879,59818VRTXVertex Pharmaceuticals$391.02-0.3%2.03%263,73319EXASExact Sciences$47.42+1.0%1.93%2,143,44820ROIVRoivant Sciences$11.93-0.1%1.70%7,333,64221CYTKCytokinetics$35.33-5.4%1.57%2,103,68622CRSPCRISPR Therapeutics$51.83-2.3%1.52%1,419,16223IONSIonis Pharmaceuticals$42.63+0.0%1.51%1,796,88124RNAAvidity Biosciences$46.58-4.1%1.37%1,574,98825RVMDRevolution Medicines$37.97-0.9%1.37%1,898,726 Geographic ExposureUnited States94.5%Bermuda1.7%Switzerland1.5%Ireland1.1%Virgin Islands, British0.5%Netherlands0.3%Canada0.1%Currency ExposureUSD100.0%Sector ExposureHealth Care98.3%Consumer Discretionary1.1%Biotechnology0.3%Energy0.1%Industry ExposureBiotechnology92.8%Health Care Equipment & Supplies3.6%Health Care Providers & Services2.3%Distributors1.0%Renewable Energy0.1%Diversified Consumer Services0.1%SubIndustry ExposureBiotechnology93.0%Life Sciences Tools & Services3.3%Health Care Services2.3%Pharmaceuticals0.8%Health Care Equipment0.2%Renewable Energy Equipment0.1%Health Care Supplies0.1%Coupon Exposure4-60.1%Maturity Exposure5-100.1% Related Companies and Tools Related Companies IBB Portfolio Companies IHI Portfolio Companies IXJ Portfolio Companies IYH Portfolio Companies FHLC Portfolio Companies FBT Portfolio Companies RYH Portfolio Companies FXH Portfolio Companies IHF Portfolio Companies RSPH Portfolio Companies This page (NYSEARCA:XBI) was last updated on 8/29/2025 by MarketBeat.com Staff From Our PartnersINVESTOR ALERT: Tiny “$3 AI Wonder Stock” on the Verge of Blasting OffRight now, we’re witnessing a monumental shift in the world.Traders Agency | SponsoredBONUS GUIDE - Ben Stein Prepares For the Next Financial CrisisWith inflation high, debt soaring, and global tensions rising, a financial storm may be brewing. 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