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SPDR S&P Biotech ETF (XBI) Holdings

SPDR S&P Biotech ETF logo
$81.40 +1.68 (+2.11%)
As of 05/20/2025 04:10 PM Eastern

Top 50 XBI Holdings

RankCompanyCurrent PriceWeightShares Held
1
Exact Sciences Co. stock logo
EXAS
Exact Sciences
$57.81
+1.5%
3.04%2,880,660
2
Alnylam Pharmaceuticals, Inc. stock logo
ALNY
Alnylam Pharmaceuticals
$291.68
-0.1%
2.94%550,778
3
Neurocrine Biosciences, Inc. stock logo
NBIX
Neurocrine Biosciences
$122.96
+0.1%
2.92%1,224,176
4
Natera, Inc. stock logo
NTRA
Natera
$154.53
+0.8%
2.88%924,003
5
United Therapeutics Co. stock logo
UTHR
United Therapeutics
$309.57
+1.4%
2.67%434,812
6
Blueprint Medicines Co. stock logo
BPMC
Blueprint Medicines
$103.00
+1.8%
2.44%1,226,902
7
Insmed Incorporated stock logo
INSM
Insmed
$68.51
+0.9%
2.42%1,803,320
8
Gilead Sciences, Inc. stock logo
GILD
Gilead Sciences
$109.11
+2.8%
2.41%1,171,271
9
AbbVie Inc. stock logo
ABBV
AbbVie
$184.75
-0.5%
2.37%629,585
10
Incyte Co. stock logo
INCY
Incyte
$65.30
+2.3%
2.37%1,971,270
11
Biogen Inc. stock logo
BIIB
Biogen
$130.55
+0.9%
2.34%952,439
12
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
$447.18
+1.5%
2.34%269,482
13
Amgen Inc. stock logo
AMGN
Amgen
$275.01
-0.3%
2.32%427,267
14
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
$614.79
+3.1%
2.21%193,628
15
Madrigal Pharmaceuticals, Inc. stock logo
MDGL
Madrigal Pharmaceuticals
$292.76
+0.7%
2.20%369,391
16
Exelixis, Inc. stock logo
EXEL
Exelixis
$44.36
-0.7%
2.08%2,843,353
17
BioMarin Pharmaceutical Inc. stock logo
BMRN
BioMarin Pharmaceutical
$59.93
+0.9%
1.96%1,617,587
18
Moderna, Inc. stock logo
MRNA
Moderna
$27.99
+6.1%
1.94%3,813,680
19
Halozyme Therapeutics, Inc. stock logo
HALO
Halozyme Therapeutics
$53.45
+0.3%
1.81%1,372,512
20
BridgeBio Pharma, Inc. stock logo
BBIO
BridgeBio Pharma
$33.71
+0.1%
1.76%2,496,841
21
Revolution Medicines, Inc. stock logo
RVMD
Revolution Medicines
$40.47
+1.4%
1.67%2,018,642
22
TG Therapeutics, Inc. stock logo
TGTX
TG Therapeutics
$35.47
+1.4%
1.56%2,246,502
23
Ionis Pharmaceuticals, Inc. stock logo
IONS
Ionis Pharmaceuticals
$34.47
+1.3%
1.44%2,177,137
24
Summit Therapeutics Inc. stock logo
SMMT
Summit Therapeutics
$24.39
+1.6%
1.42%2,837,918
25
CRISPR Therapeutics AG stock logo
CRSP
CRISPR Therapeutics
$39.25
+1.5%
1.34%1,803,872
26
Roivant Sciences Ltd. stock logo
ROIV
Roivant Sciences
$11.04
+1.8%
1.33%6,123,795
27
Viking Therapeutics, Inc. stock logo
VKTX
Viking Therapeutics
$28.67
+4.3%
1.27%2,270,183
28
SpringWorks Therapeutics, Inc. stock logo
SWTX
SpringWorks Therapeutics
$46.31
+0.1%
1.25%1,370,233
29
Cytokinetics, Incorporated stock logo
CYTK
Cytokinetics
$32.66
+6.2%
1.16%1,821,878
30
Alkermes plc stock logo
ALKS
Alkermes
$31.67
+0.7%
1.15%1,858,484
31
ADMA Biologics, Inc. stock logo
ADMA
ADMA Biologics
$20.44
+1.2%
1.12%2,758,849
32
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
$31.64
+4.7%
1.04%1,788,943
33
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
$36.57
+14.2%
1.02%1,628,254
34
Nuvalent, Inc. stock logo
NUVL
Nuvalent
$75.88
+3.5%
0.92%632,387
35
Scholar Rock Holding Co. stock logo
SRRK
Scholar Rock
$31.54
+4.6%
0.89%1,379,429
36
Sarepta Therapeutics, Inc. stock logo
SRPT
Sarepta Therapeutics
$39.99
+5.4%
0.87%1,203,975
37
Soleno Therapeutics, Inc. stock logo
SLNO
Soleno Therapeutics
$75.05
-0.7%
0.87%572,611
38
ACADIA Pharmaceuticals Inc. stock logo
ACAD
ACADIA Pharmaceuticals
$21.69
-1.4%
0.86%2,474,199
39
Arcellx, Inc. stock logo
ACLX
Arcellx
$60.54
+3.5%
0.85%722,690
40
Crinetics Pharmaceuticals, Inc. stock logo
CRNX
Crinetics Pharmaceuticals
$31.37
+1.4%
0.83%1,261,611
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41
Rhythm Pharmaceuticals, Inc. stock logo
RYTM
Rhythm Pharmaceuticals
$63.87
+4.3%
0.83%713,178
42
Veracyte, Inc. stock logo
VCYT
Veracyte
$28.81
-0.7%
0.83%1,370,802
43
Krystal Biotech, Inc. stock logo
KRYS
Krystal Biotech
$131.54
-0.6%
0.82%298,507
44
Twist Bioscience Co. stock logo
TWST
Twist Bioscience
$30.91
+1.7%
0.80%1,226,401
45
Ultragenyx Pharmaceutical Inc. stock logo
RARE
Ultragenyx Pharmaceutical
$37.35
+3.2%
0.78%1,097,051
46
Apellis Pharmaceuticals, Inc. stock logo
APLS
Apellis Pharmaceuticals
$18.51
+4.8%
0.77%2,225,195
47
Travere Therapeutics, Inc. stock logo
TVTX
Travere Therapeutics
$17.56
+3.2%
0.76%1,791,410
48
Akero Therapeutics, Inc. stock logo
AKRO
Akero Therapeutics
$47.57
+24.7%
0.75%915,070
49
Recursion Pharmaceuticals, Inc. stock logo
RXRX
Recursion Pharmaceuticals
$4.55
+0.9%
0.68%7,392,196
50
Agios Pharmaceuticals, Inc. stock logo
AGIO
Agios Pharmaceuticals
$30.17
+1.1%
0.67%1,156,574

Geographic Exposure

  • United States
    94.9%
  • Switzerland
    1.4%
  • Bermuda
    1.3%
  • Ireland
    1.2%
  • Virgin Islands, British
    0.5%
  • Netherlands
    0.3%
  • Canada
    0.1%

Currency Exposure

  • USD
    100.0%

Sector Exposure

  • Health Care
    98.3%
  • Consumer Discretionary
    1.0%
  • Biotechnology
    0.6%

Industry Exposure

  • Biotechnology
    90.8%
  • Health Care Equipment & Supplies
    5.2%
  • Health Care Providers & Services
    2.8%
  • Distributors
    0.8%
  • Diversified Consumer Services
    0.2%

SubIndustry Exposure

  • Biotechnology
    90.9%
  • Life Sciences Tools & Services
    4.7%
  • Health Care Services
    2.8%
  • Pharmaceuticals
    0.7%
  • Health Care Equipment
    0.4%
  • Health Care Supplies
    0.1%

Coupon Exposure

  • 4-6
    0.1%

Maturity Exposure

  • 5-10
    0.1%

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This page (NYSEARCA:XBI) was last updated on 5/21/2025 by MarketBeat.com Staff
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