SPDR S&P Biotech ETF (XBI) Holdings $85.43 +0.11 (+0.13%) Closing price 08/8/2025 04:10 PM EasternExtended Trading$85.48 +0.05 (+0.06%) As of 08/8/2025 07:55 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Holdings Stock AnalysisChartDividendHeadlinesHoldingsOwnershipRatingsShort InterestBuy This Stock Top 25 XBI HoldingsRankCompanyCurrent PriceWeightShares Held1MRNAModerna$26.12-1.8%2.72%4,198,6342ALNYAlnylam Pharmaceuticals$438.93+0.9%2.60%390,2453EXELExelixis$37.72+0.9%2.60%2,812,2104NBIXNeurocrine Biosciences$125.01-0.5%2.57%938,2955UTHRUnited Therapeutics$301.50+0.7%2.55%421,3736HALOHalozyme Therapeutics$62.90+1.3%2.53%2,163,6207INSMInsmed$109.55+0.2%2.53%1,189,0968REGNRegeneron Pharmaceuticals$563.00+0.6%2.53%224,6759VRTXVertex Pharmaceuticals$366.54-2.4%2.46%257,62810AMGNAmgen$288.23+1.2%2.44%399,268 Get the Latest News and Ratings for XBI and Related StocksEnter your email address below to receive the latest news and analysts' ratings for SPDR S&P Biotech ETF and its competitors with MarketBeat's FREE daily newsletter. 11BMRNBioMarin Pharmaceutical$57.33-3.6%2.42%2,038,29212ABBVAbbVie$198.10-0.4%2.39%608,37113GILDGilead Sciences$119.41+8.3%2.39%1,065,92914INCYIncyte$78.39+0.2%2.38%1,692,23815BBIOBridgeBio Pharma$46.58+1.4%2.30%2,384,95816BIIBBiogen$130.67+2.3%2.27%875,63217EXASExact Sciences$40.99-5.0%2.19%2,093,15418MDGLMadrigal Pharmaceuticals$345.73+1.0%2.06%297,50019BPMCBlueprint Medicines$129.462.03%756,46920NTRANatera$151.95+7.7%2.01%698,60421CRSPCRISPR Therapeutics$55.00-1.7%1.87%1,385,76922TGTXTG Therapeutics$26.71-4.2%1.79%2,281,01923ROIVRoivant Sciences$11.49-0.5%1.70%7,160,79324CYTKCytokinetics$34.11-3.2%1.59%2,054,05625IONSIonis Pharmaceuticals$41.64+1.4%1.52%1,754,383 Geographic ExposureUnited States94.4%Bermuda1.7%Switzerland1.6%Ireland1.1%Virgin Islands, British0.5%Netherlands0.2%Canada0.1%Currency ExposureUSD100.0%Sector ExposureHealth Care98.5%Consumer Discretionary1.0%Biotechnology0.3%Energy0.1%Industry ExposureBiotechnology93.1%Health Care Equipment & Supplies3.7%Health Care Providers & Services2.0%Distributors0.9%Renewable Energy0.1%Diversified Consumer Services0.1%SubIndustry ExposureBiotechnology93.2%Life Sciences Tools & Services3.3%Health Care Services2.0%Pharmaceuticals0.7%Health Care Equipment0.2%Renewable Energy Equipment0.1%Health Care Supplies0.1% Related Companies and Tools Related Companies IHI Portfolio Companies IBB Portfolio Companies IXJ Portfolio Companies IYH Portfolio Companies FHLC Portfolio Companies FBT Portfolio Companies RYH Portfolio Companies FXH Portfolio Companies RSPH Portfolio Companies LABU Portfolio Companies This page (NYSEARCA:XBI) was last updated on 8/9/2025 by MarketBeat.com Staff From Our PartnersYour blueprint for crypto wealthMark August 12th on your calendar. 27 of crypto's most successful minds are about to reveal everything…Crypto 101 Media | SponsoredTrump’s national nightmare is herePorter Stansberry and Jeff Brown say a new U.S. national emergency is already underway — and it could trigger ...Porter & Company | SponsoredHIDDEN IN THE BOOK OF GENESIS…“This land I will give to you…” — a 4,000-year-old line from Genesis may hold the key to unlocking a $150 tril...Paradigm Press | SponsoredMan Who Called Nvidia at $1.10 Says Buy This Now...In 2004, one man called Nvidia before just about anyone knew it existed. 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