SPDR S&P Biotech ETF (XBI) Holdings List

$160.46 0.00 (0.00%)

As of 07/2/2026 04:10 PM Eastern

What stocks does XBI hold?

The SPDR S&P Biotech ETF (XBI) top stock holdings include Apogee Therapeutics, Moderna, and Twist Bioscience. The top 25 XBI holdings ordered by weight make up 30.50% of the total fund. XBI is an equity fund in the sector category that invests in publicly traded companies, focused on health care strategies within the North America region. This page includes a complete XBI stock holdings list ranked by weight, along with a full breakdown of sector, geographic, industry, and currency exposure.

Top 25 XBI Holdings

Rank	Company	Current Price	Weight	Shares Held
1	APGE Apogee Therapeutics	$132.91	1.48%	1,199,234
2	MRNA Moderna	$79.76	1.41%	2,156,912
3	TWST Twist Bioscience	$99.24	1.40%	1,463,691
4	ORKA Oruka Therapeutics	$85.21	1.37%	1,549,262
5	KYMR Kymera Therapeutics	$113.51	1.35%	1,268,064
6	VKTX Viking Therapeutics	$37.44	1.30%	3,574,768
7	PRAX Praxis Precision Medicines	$318.52	1.29%	412,207
8	ERAS Erasca	$18.47	1.27%	7,419,695
9	RVMD Revolution Medicines	$189.24	1.20%	687,949
10	RYTM Rhythm Pharmaceuticals	$114.17	1.20%	1,157,392
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11	CGON CG Oncology	$70.36	1.20%	1,806,242
12	SLS SELLAS Life Sciences Group	$14.98	1.19%	8,622,810
13	PCVX Vaxcyte	$58.39	1.18%	2,184,032
14	DNTH Dianthus Therapeutics	$94.34	1.18%	1,298,103
15	CYTK Cytokinetics	$86.49	1.17%	1,478,986
16	NTRA Natera	$279.32	1.16%	458,237
17	SRRK Scholar Rock	$54.88	1.15%	2,249,906
18	ROIV Roivant Sciences	$35.13	1.15%	3,491,718
19	MIRM Mirum Pharmaceuticals	$125.59	1.15%	1,055,296
20	COGT Cogent Biosciences	$38.69	1.14%	3,161,289
21	RARE Ultragenyx Pharmaceutical	$33.47	1.14%	3,653,348
22	TVTX Travere Therapeutics	$56.90 0.0%	1.12%	2,122,275
23	ALKS Alkermes	$54.58	1.10%	2,262,805
24	KRYS Krystal Biotech	$375.07	1.10%	317,561
25	CELC Celcuity	$107.95	1.10%	1,124,179

XBI Geographic Exposure

XBI's largest geographic exposure is United States at 93.5%, followed by Ireland at 1.2%.

United States
93.5%
Ireland
1.2%
Bermuda
1.2%
Switzerland
1.1%
Netherlands
1.0%
Virgin Islands, British
0.6%
Canada
0.2%

XBI Currency Exposure

XBI is exclusively exposed to USD.

USD
100.0%

XBI Sector Exposure

XBI's largest sector exposure is Health Care at 97.9%, followed by Energy at 0.2%.

Health Care
97.9%
Energy
0.2%
Consumer Discretionary
0.2%

XBI Industry Exposure

XBI's largest industry exposure is Biotechnology at 93.6%, followed by Health Care Equipment & Supplies at 1.9%.

Biotechnology
93.6%
Health Care Equipment & Supplies
1.9%
Diversified Consumer Services
1.4%
Health Care Providers & Services
1.2%
Renewable Energy
0.2%

XBI Sub-Industry Exposure

XBI's largest sub-industry exposure is Biotechnology at 92.6%, followed by Life Sciences Tools & Services at 1.5%.

Biotechnology
92.6%
Life Sciences Tools & Services
1.5%
Health Care Services
1.2%
Pharmaceuticals
1.0%
Health Care Equipment
0.3%
Renewable Energy Equipment
0.2%
Health Care Supplies
0.1%

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This page (NYSEARCA:XBI) was last updated on 7/4/2026 by MarketBeat.com Staff.

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SPDR S&P Biotech ETF (XBI) Holdings List