SPDR S&P Biotech ETF (XBI) Holdings $102.67 -0.97 (-0.93%) As of 11:55 AM Eastern This is a fair market value price provided by Polygon.io. Learn more. Add Compare Share Share Holdings Stock AnalysisChartDividendHeadlinesHoldingsOwnershipRatingsShort InterestBuy This Stock Top 25 XBI HoldingsRankCompanyCurrent PriceWeightShares Held1CRSPCRISPR Therapeutics$70.19+3.6%2.48%2,076,0582MRNAModerna$27.54-3.3%2.07%4,455,3533ABBVAbbVie$230.28-1.6%1.99%511,6074UTHRUnited Therapeutics$453.28+0.0%1.99%273,1825EXELExelixis$40.01-0.2%1.95%2,872,9816BIIBBiogen$154.05-3.6%1.93%759,5127REGNRegeneron Pharmaceuticals$585.48-2.4%1.92%194,8768AMGNAmgen$294.12-1.3%1.90%388,9179IONSIonis Pharmaceuticals$69.02-0.2%1.90%1,692,39510VRTXVertex Pharmaceuticals$402.90-0.1%1.87%278,78111INSMInsmed$158.28+0.7%1.86%742,28712MDGLMadrigal Pharmaceuticals$442.31-0.2%1.86%251,83413EXASExact Sciences$57.63+1.6%1.82%1,977,57814BMRNBioMarin Pharmaceutical$55.61+0.3%1.81%1,987,33115RVMDRevolution Medicines$46.58-0.3%1.81%2,419,83316BBIOBridgeBio Pharma$54.61+3.3%1.79%2,045,17317INCYIncyte$87.23+0.4%1.78%1,255,83218ALNYAlnylam Pharmaceuticals$452.00-1.0%1.75%230,74019NBIXNeurocrine Biosciences$139.43+1.8%1.72%766,82320TGTXTG Therapeutics$36.76+0.1%1.72%2,853,36021GILDGilead Sciences$113.58+0.8%1.71%939,84522RNAAvidity Biosciences$46.18-1.7%1.69%2,334,34923HALOHalozyme Therapeutics$66.97-2.9%1.68%1,428,90424NTRANatera$170.38+1.8%1.68%637,92525ROIVRoivant Sciences$16.26+0.6%1.65%6,303,388 Geographic ExposureUnited States92.5%Switzerland2.5%Bermuda1.7%Ireland1.2%Netherlands1.0%Virgin Islands, British0.6%Canada0.1%Currency ExposureUSD100.0%Sector ExposureHealth Care98.1%Consumer Discretionary1.0%Biotechnology0.6%Energy0.2%Industry ExposureBiotechnology93.4%Health Care Equipment & Supplies3.6%Health Care Providers & Services1.7%Distributors0.9%Diversified Consumer Services0.2%Renewable Energy0.2%SubIndustry ExposureBiotechnology93.5%Life Sciences Tools & Services3.2%Health Care Services1.7%Pharmaceuticals0.7%Health Care Equipment0.3%Renewable Energy Equipment0.2%Health Care Supplies0.1%Coupon Exposure4-60.1%Maturity Exposure5-100.1% Related Companies and Tools Related Companies IBB Portfolio Companies IHI Portfolio Companies IXJ Portfolio Companies IYH Portfolio Companies FHLC Portfolio Companies FBT Portfolio Companies RYH Portfolio Companies FXH Portfolio Companies IHF Portfolio Companies LABU Portfolio Companies This page (NYSEARCA:XBI) was last updated on 10/7/2025 by MarketBeat.com Staff From Our PartnersMagnificent 7 being replaced by the “Hidden 7”?BULLISH: It's time to buy this 'hidden' AI stock An award-winning stock-rating system has turned BULLISH on...Chaikin Analytics | SponsoredU.S. Government Sparking Crypto RallyU.S. Puts GDP on the Blockchain Could this spark the next crypto supercycle? 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