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Silverarc Capital Management, LLC Top Holdings and 13F Report (2025)

About Silverarc Capital Management, LLC

Investment Activity

  • Silverarc Capital Management, LLC has $489.00 million in total holdings as of March 31, 2025.
  • Silverarc Capital Management, LLC owns shares of 69 different stocks, but just 27 companies or ETFs make up 80% of its holdings.
  • Approximately 32.97% of the portfolio was purchased this quarter.
  • About 20.99% of the portfolio was sold this quarter.
  • This quarter, Silverarc Capital Management, LLC has purchased 61 new stocks and bought additional shares in 27 stocks.
  • Silverarc Capital Management, LLC sold shares of 16 stocks and completely divested from 16 stocks this quarter.

Largest Holdings

Verona Pharma
$34,657,413
Merus
$34,135,874
Nuvalent
$31,135,157
Akero Therapeutics
$29,145,276
Insmed
$24,517,012

Largest New Holdings this Quarter

834203309 - Soleno Therapeutics
$11,890,495 Holding
64125C109 - Neurocrine Biosciences
$8,027,680 Holding
603170101 - Mineralys Therapeutics
$5,373,062 Holding
G01767105 - Alkermes
$4,123,240 Holding
67576A100 - Ocular Therapeutix
$4,043,008 Holding

Largest Purchases this Quarter

KalVista Pharmaceuticals
1,086,811 shares (about $12.54M)
Soleno Therapeutics
166,417 shares (about $11.89M)
89bio
1,413,987 shares (about $10.28M)
Neurocrine Biosciences
72,583 shares (about $8.03M)
Disc Medicine
126,090 shares (about $6.26M)

Largest Sales this Quarter

Centessa Pharmaceuticals
366,194 shares (about $5.27M)
Avidity Biosciences
132,339 shares (about $3.91M)
Insmed
50,864 shares (about $3.88M)
AKERO THERAPEUTICS INC
39,400 shares (about $1.59M)
Kodiak Sciences
558,193 shares (about $1.57M)

Sector Allocation Over Time

Map of 500 Largest Holdings ofSilverarc Capital Management, LLC

 
 
Selling
 
 
Neutral
 
 
Buying
Issuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSector
Verona Pharma plc stock logo
VRNA
Verona Pharma
$34,657,413$1,895,684 5.8%545,8727.1%Medical
Merus stock logo
MRUS
Merus
$34,135,874$5,479,108 19.1%811,0217.0%Medical
Nuvalent, Inc. stock logo
NUVL
Nuvalent
$31,135,157$2,766,164 9.8%439,0186.4%Medical
Akero Therapeutics, Inc. stock logo
AKRO
Akero Therapeutics
$29,145,276$792,234 -2.6%719,9926.0%Medical
Insmed Incorporated stock logo
INSM
Insmed
$24,517,012$3,880,415 -13.7%321,3665.0%Medical
KalVista Pharmaceuticals, Inc. stock logo
KALV
KalVista Pharmaceuticals
$19,606,275$12,541,799 177.5%1,698,9844.0%Medical
Veracyte, Inc. stock logo
VCYT
Veracyte
$18,793,119$3,870,837 25.9%633,8323.8%Medical
Rhythm Pharmaceuticals, Inc. stock logo
RYTM
Rhythm Pharmaceuticals
$17,882,937$3,374,666 23.3%337,6053.7%Medical
Syndax Pharmaceuticals, Inc. stock logo
SNDX
Syndax Pharmaceuticals
$16,083,817$968,353 6.4%1,309,2243.3%Medical
UroGen Pharma Ltd. stock logo
URGN
UroGen Pharma
$15,275,607$2,883,176 23.3%1,381,1583.1%Medical
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
$12,141,930$3,906,647 -24.3%411,3122.5%Medical
Soleno Therapeutics, Inc. stock logo
SLNO
Soleno Therapeutics
$11,890,495$11,890,495 New Holding166,4172.4%Medical
Ascendis Pharma A/S stock logo
ASND
Ascendis Pharma A/S
$11,806,551$3,781,164 47.1%75,7512.4%Medical
Disc Medicine, Inc. stock logo
IRON
Disc Medicine
$11,738,420$6,259,107 114.2%236,4712.4%Medical
ORIC Pharmaceuticals, Inc. stock logo
ORIC
ORIC Pharmaceuticals
$11,496,139$4,921,225 74.8%2,060,2402.4%Medical
89bio, Inc. stock logo
ETNB
89bio
$10,981,320$10,279,685 1,465.1%1,510,4982.2%Medical
Erasca, Inc. stock logo
ERAS
Erasca
$10,094,155$240,990 -2.3%7,367,9962.1%Medical
Wave Life Sciences Ltd. stock logo
WVE
Wave Life Sciences
$8,487,022$3,567,134 72.5%1,050,3741.7%Medical
Neurocrine Biosciences, Inc. stock logo
NBIX
Neurocrine Biosciences
$8,027,680$8,027,680 New Holding72,5831.6%Medical
Travere Therapeutics, Inc. stock logo
TVTX
Travere Therapeutics
$7,326,574$2,356,193 47.4%408,8491.5%Medical
AKERO THERAPEUTICS INC
$7,310,688$1,594,912 -17.9%180,6001.5%CALL
Gossamer Bio, Inc. stock logo
GOSS
Gossamer Bio
$6,952,752$163,721 2.4%6,320,6841.4%Medical
Gilead Sciences, Inc. stock logo
GILD
Gilead Sciences
$6,950,349$5,829,849 520.3%62,0291.4%Medical
HELIX ACQUISITION CORP II
$6,931,341$1,130,271 19.5%613,3931.4%CL A ORD SHS
Elutia Inc. stock logo
ELUT
Elutia
$6,755,242$2,246,096 49.8%2,670,0561.4%Medical
PRAXIS PRECISION MEDICINES I
$6,289,222$3,543,041 129.0%166,0741.3%COM NEW
Mineralys Therapeutics, Inc. stock logo
MLYS
Mineralys Therapeutics
$5,373,062$5,373,062 New Holding338,3541.1%Medical
Compugen Ltd. stock logo
CGEN
Compugen
$4,227,328$1,855,737 78.2%2,895,4300.9%Medical
Tarsus Pharmaceuticals, Inc. stock logo
TARS
Tarsus Pharmaceuticals
$4,177,973$789,865 23.3%81,3310.9%Medical
Alkermes plc stock logo
ALKS
Alkermes
$4,123,240$4,123,240 New Holding124,8710.8%Medical
Ocular Therapeutix, Inc. stock logo
OCUL
Ocular Therapeutix
$4,043,008$4,043,008 New Holding551,5700.8%Medical
BridgeBio Pharma, Inc. stock logo
BBIO
BridgeBio Pharma
$3,837,270$3,837,270 New Holding111,0000.8%Medical
Kura Oncology, Inc. stock logo
KURA
Kura Oncology
$3,837,035$3,837,035 New Holding581,3690.8%Medical
Celldex Therapeutics, Inc. stock logo
CLDX
Celldex Therapeutics
$3,738,210$1,063,554 -22.1%205,9620.8%Medical
DIANTHUS THERAPEUTICS INC
$3,452,659$3,452,659 New Holding190,3340.7%COM
Madrigal Pharmaceuticals, Inc. stock logo
MDGL
Madrigal Pharmaceuticals
$3,426,243$3,426,243 New Holding10,3440.7%Medical
Cerus Co. stock logo
CERS
Cerus
$3,414,586$1,208,339 54.8%2,456,5370.7%Medical
TELA Bio, Inc. stock logo
TELA
TELA Bio
$3,380,971$359,120 -9.6%2,771,2880.7%Medical
Centessa Pharmaceuticals plc stock logo
CNTA
Centessa Pharmaceuticals
$3,347,060$5,265,870 -61.1%232,7580.7%Medical
Trevi Therapeutics, Inc. stock logo
TRVI
Trevi Therapeutics
$3,333,700$1,284,632 -27.8%530,0000.7%Medical
Blueprint Medicines Co. stock logo
BPMC
Blueprint Medicines
$3,305,406$3,305,406 New Holding37,3450.7%Medical
Structure Therapeutics Inc. stock logo
GPCR
Structure Therapeutics
$3,255,474$617,517 23.4%188,0690.7%Medical
BENITEC BIOPHARMA INC
$3,252,500$3,252,500 New Holding250,0000.7%COM NEW
Liquidia Co. stock logo
LQDA
Liquidia
$3,157,341$3,157,341 New Holding214,0570.6%Medical
PTC Therapeutics, Inc. stock logo
PTCT
PTC Therapeutics
$3,077,423$3,077,423 New Holding60,3890.6%Medical
METSERA INC
$3,069,300$3,069,300 New Holding112,7590.6%COM
SOLENO THERAPEUTICS INC
$3,036,625$3,036,625 New Holding42,5000.6%PUT
Biodesix, Inc. stock logo
BDSX
Biodesix
$2,562,323$146,219 -5.4%4,098,4060.5%Medical
Delcath Systems, Inc. stock logo
DCTH
Delcath Systems
$2,437,413$460,126 23.3%191,4700.5%Medical
uniQure stock logo
QURE
uniQure
$2,156,040$1,096,040 103.4%203,4000.4%Medical
KINIKSA PHARMACEUTICALS INTL
$1,959,255$1,959,255 New Holding88,2150.4%ORD SHS CL A
Solid Biosciences Inc. stock logo
SLDB
Solid Biosciences
$1,673,284$1,673,284 New Holding452,2390.3%Medical
Compass Therapeutics, Inc. stock logo
CMPX
Compass Therapeutics
$1,662,251$1,662,251 New Holding874,8690.3%Medical
C4 Therapeutics, Inc. stock logo
CCCC
C4 Therapeutics
$1,411,680$542,130 -27.7%882,3000.3%Medical
KALA BIO, Inc. stock logo
KALA
KALA BIO
$1,410,033$86,002 6.5%246,0790.3%Medical
Unicycive Therapeutics, Inc. stock logo
UNCY
Unicycive Therapeutics
$1,387,515$42,094 -2.9%2,413,4890.3%Medical
ABIVAX SA
$1,318,131$463,869 -26.0%210,9010.3%SPONSORED ADS
Kodiak Sciences Inc. stock logo
KOD
Kodiak Sciences
$1,239,269$1,565,732 -55.8%441,8070.3%Medical
SIONNA THERAPEUTICS INC
$1,193,883$1,193,883 New Holding114,1380.2%COM
InflaRx stock logo
IFRX
InflaRx
$1,184,798$1,184,798 New Holding1,161,5670.2%Medical
Mersana Therapeutics, Inc. stock logo
MRSN
Mersana Therapeutics
$1,063,063$1,063,063 New Holding3,088,5050.2%Medical
Modular Medical, Inc. stock logo
MODD
Modular Medical
$1,045,180$341,316 -24.6%958,8810.2%Medical
RADIOPHARM THERANOSTICS LTD
$901,4230.0%187,4060.2%SPONSORED ADS
AARDVARK THERAPEUTICS INC
$897,415$897,415 New Holding119,4960.2%COM
Xenon Pharmaceuticals Inc. stock logo
XENE
Xenon Pharmaceuticals
$339,560$339,560 New Holding10,1210.1%Medical
AVADEL PHARMACEUTICALS PLC
$308,236$308,236 New Holding39,3660.1%COM SHS
FRACTYL HEALTH INC
$282,563$72,026 34.2%237,4480.1%COM
Vaxart, Inc. stock logo
VXRT
Vaxart
$278,317$160,341 -36.6%683,8250.1%Medical
Rocket Pharmaceuticals, Inc. stock logo
RCKTW
Rocket Pharmaceuticals
$4,9270.0%104,8280.0%Medical
Pliant Therapeutics, Inc. stock logo
PLRX
Pliant Therapeutics
$0$17,326,465 -100.0%00.0%Medical
Intra-Cellular Therapies, Inc. stock logo
ITCI
Intra-Cellular Therapies
$0$14,957,179 -100.0%00.0%Medical
Poseida Therapeutics, Inc. stock logo
PSTX
Poseida Therapeutics
$0$9,718,147 -100.0%00.0%Medical
Scholar Rock Holding Co. stock logo
SRRK
Scholar Rock
$0$7,919,762 -100.0%00.0%Medical
Cogent Biosciences, Inc. stock logo
COGT
Cogent Biosciences
$0$7,184,869 -100.0%00.0%Medical
Ultragenyx Pharmaceutical Inc. stock logo
RARE
Ultragenyx Pharmaceutical
$0$5,233,003 -100.0%00.0%Medical
Incyte Co. stock logo
INCY
Incyte
$0$3,384,430 -100.0%00.0%Medical
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
$0$3,338,906 -100.0%00.0%Medical
Geron Co. stock logo
GERN
Geron
$0$3,256,878 -100.0%00.0%Medical
SYNDAX PHARMACEUTICALS INC
$0$2,279,128 -100.0%00.0%CALL
Viridian Therapeutics, Inc. stock logo
VRDN
Viridian Therapeutics
$0$1,917,000 -100.0%00.0%Medical
NEUMORA THERAPEUTICS INC.
$0$1,560,320 -100.0%00.0%CALL
Olema Pharmaceuticals, Inc. stock logo
OLMA
Olema Pharmaceuticals
$0$1,360,028 -100.0%00.0%Medical
EyePoint Pharmaceuticals, Inc. stock logo
EYPT
EyePoint Pharmaceuticals
$0$903,491 -100.0%00.0%Medical
Karyopharm Therapeutics Inc. stock logo
KPTI
Karyopharm Therapeutics
$0$403,068 -100.0%00.0%Medical
BIOAGE LABS INC
$0$231,449 -100.0%00.0%COM

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