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Comparative Price Performance Over Time

Compare Price & Volume

Company	Current Price	50-Day Moving Average	52-Week Range	Market Cap	Beta	Avg. Volume	Today's Volume
EW Edwards Lifesciences	$78.07 -0.9%	$76.25	$58.93 ▼ $95.25	$45.79B	1.11	5.25 million shs	3.67 million shs
ISRG Intuitive Surgical	$512.06 -2.7%	$538.20	$413.82 ▼ $616.00	$183.53B	1.64	1.68 million shs	2.88 million shs
PFE Pfizer	$25.65 -0.5%	$23.86	$20.92 ▼ $31.54	$145.83B	0.58	41.80 million shs	31.85 million shs
SYK Stryker	$389.24 -1.4%	$384.57	$314.93 ▼ $406.19	$148.57B	0.91	1.35 million shs	801,040 shs

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Compare Price Performance

Company	1-Day Performance	7-Day Performance	30-Day Performance	90-Day Performance	1-Year Performance
EW Edwards Lifesciences	+2.05%	+2.63%	+4.01%	+13.66%	-15.98%
ISRG Intuitive Surgical	-0.39%	-3.25%	-0.67%	+6.57%	+18.28%
PFE Pfizer	+0.81%	+1.27%	+6.06%	+17.72%	-9.11%
SYK Stryker	+0.67%	+0.68%	+2.46%	+12.76%	+16.99%

Compare MarketRank™

Company	Overall Score	Analyst's Opinion	Short Interest Score	Dividend Strength	ESG Score	News and Social Media Sentiment	Company Ownership	Earnings & Valuation
EW Edwards Lifesciences	4.4957 of 5 stars	2.2	3.0	0.0	4.0	3.5	2.5	2.5
ISRG Intuitive Surgical	4.685 of 5 stars	3.4	3.0	0.0	4.0	3.0	2.5	1.9
PFE Pfizer	4.9782 of 5 stars	3.2	3.0	4.2	4.5	3.3	1.7	3.1
SYK Stryker	4.8116 of 5 stars	3.4	2.0	3.3	4.2	3.0	2.5	1.3

Compare Analyst Forecasts

Company	Consensus Rating Score	Consensus Rating	Consensus Price Target	% Upside from Current Price
EW Edwards Lifesciences	2.40	Hold	$80.40	3.01% Upside
ISRG Intuitive Surgical	2.70	Moderate Buy	$592.59	16.02% Upside
PFE Pfizer	2.45	Hold	$28.55	11.37% Upside
SYK Stryker	2.79	Moderate Buy	$428.55	10.08% Upside

Current Analyst Ratings Breakdown

Latest ISRG, EW, SYK, and PFE Analyst Ratings

Date	Company	Brokerage	Action	Rating	Price Target
7/8/2025	EW Edwards Lifesciences	Evercore ISI Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	In-Line ➝ In-Line	$73.00 ➝ $77.00
7/8/2025	ISRG Intuitive Surgical	Evercore ISI Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	In-Line ➝ In-Line	$470.00 ➝ $550.00
7/8/2025	SYK Stryker	Evercore ISI Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	Outperform ➝ Outperform	$390.00 ➝ $415.00
6/9/2025	ISRG Intuitive Surgical	Deutsche Bank Aktiengesellschaft Subscribe to MarketBeat All Access for the recommendation accuracy rating	Downgrade	Hold ➝ Sell	$515.00 ➝ $440.00
6/5/2025	ISRG Intuitive Surgical	Erste Group Bank Subscribe to MarketBeat All Access for the recommendation accuracy rating	Upgrade	Hold ➝ Buy
6/2/2025	EW Edwards Lifesciences	Dbs Bank Subscribe to MarketBeat All Access for the recommendation accuracy rating	Upgrade	Hold
5/29/2025	PFE Pfizer	Berenberg Bank Subscribe to MarketBeat All Access for the recommendation accuracy rating	Lower Price Target	Hold	$28.00 ➝ $25.00
5/22/2025	EW Edwards Lifesciences	Citigroup Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Buy ➝ Buy	$84.00 ➝ $95.00
5/22/2025	ISRG Intuitive Surgical	Citigroup Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Buy ➝ Buy	$590.00 ➝ $650.00
5/22/2025	SYK Stryker	Citigroup Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Buy ➝ Buy	$443.00 ➝ $455.00
5/21/2025	PFE Pfizer	Jefferies Financial Group Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	Buy	$32.00 ➝ $33.00

(Data available from 7/11/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)

Compare Sales & Book Value

Company	Annual Revenue	Price/Sales	Cashflow	Price/Cash	Book Value	Price/Book
EW Edwards Lifesciences	$5.44B	8.42	$2.76 per share	28.27	$17.06 per share	4.58
ISRG Intuitive Surgical	$8.35B	21.92	$7.73 per share	66.11	$46.41 per share	11.01
PFE Pfizer	$62.46B	2.33	$4.37 per share	5.86	$15.62 per share	1.64
SYK Stryker	$22.60B	6.58	$14.98 per share	25.99	$54.13 per share	7.19

Compare Profitability & Earnings

Company	Net Income	EPS	Trailing P/E Ratio	Forward P/E Ratio	P/E Growth	Net Margins	Return on Equity (ROE)	Return on Assets (ROA)	Next Earnings Date
EW Edwards Lifesciences	$4.17B	$7.00	11.15	28.38	3.88	75.48%	16.62%	12.64%	7/23/2025 (Estimated)
ISRG Intuitive Surgical	$2.32B	$6.82	74.78	66.94	5.60	28.41%	14.43%	12.81%	7/22/2025 (Estimated)
PFE Pfizer	$8.03B	$1.38	18.58	8.46	0.93	12.62%	20.33%	8.53%	8/5/2025 (Estimated)
SYK Stryker	$2.99B	$7.40	52.61	26.25	2.96	12.31%	23.74%	11.25%	7/31/2025 (Estimated)

Latest ISRG, EW, SYK, and PFE Earnings

Date	Quarter	Company	Consensus Estimate	Reported EPS	Beat/Miss	Gap EPS	Revenue Estimate	Actual Revenue
8/5/2025	Q2 2025	PFE Pfizer	$0.57	N/A	N/A	N/A	$13.43 billion	N/A
7/31/2025	Q2 2025	SYK Stryker	$3.06	N/A	N/A	N/A	$5.92 billion	N/A
7/23/2025	Q2 2025	EW Edwards Lifesciences	$0.62	N/A	N/A	N/A	$1.49 billion	N/A
7/22/2025	Q2 2025	ISRG Intuitive Surgical	$1.92	N/A	N/A	N/A	$2.35 billion	N/A
5/1/2025	Q1 2025	SYK Stryker	$2.73	$2.84	+$0.11	$1.69	$5.68 billion	$5.87 billion
4/29/2025	Q1 2025	PFE Pfizer	$0.67	$0.92	+$0.25	$0.52	$14.43 billion	$13.72 billion
4/23/2025	Q1 2025	EW Edwards Lifesciences	$0.60	$0.64	+$0.04	$0.61	$1.40 billion	$1.41 billion
4/22/2025	Q1 2025	ISRG Intuitive Surgical	$1.71	$1.81	+$0.10	$1.92	$2.19 billion	$2.25 billion

Compare Dividends

Company	Annual Payout	Dividend Yield	3-Year Dividend Growth	Payout Ratio	Years of Consecutive Growth
EW Edwards Lifesciences	N/A	N/A	N/A	N/A	N/A
ISRG Intuitive Surgical	N/A	N/A	N/A	N/A	N/A
PFE Pfizer	$1.72	6.71%	N/A	124.64%	16 Years
SYK Stryker	$3.36	0.86%	N/A	45.41%	32 Years

Latest ISRG, EW, SYK, and PFE Dividends

Announcement	Company	Period	Amount	Yield	Ex-Dividend Date	Record Date	Payable Date
6/25/2025	PFE Pfizer	quarterly	$0.43	7.08%	7/25/2025	7/25/2025	9/2/2025
5/8/2025	SYK Stryker	quarterly	$0.84	0.88%	6/30/2025	6/30/2025	7/31/2025
4/23/2025	PFE Pfizer	quarterly	$0.43	7.69%	5/9/2025	5/9/2025	6/13/2025

(Data available from 1/1/2013 forward)

Compare Debt

Company	Debt-to-Equity Ratio	Current Ratio	Quick Ratio
EW Edwards Lifesciences	0.06	4.45	3.66
ISRG Intuitive Surgical	N/A	4.98	3.97
PFE Pfizer	0.64	1.26	0.96
SYK Stryker	0.69	1.64	1.00

Compare Ownership

Institutional Ownership

Company	Institutional Ownership
EW Edwards Lifesciences	79.46%
ISRG Intuitive Surgical	83.64%
PFE Pfizer	68.36%
SYK Stryker	77.09%

Insider Ownership

Company	Insider Ownership
EW Edwards Lifesciences	1.29%
ISRG Intuitive Surgical	0.70%
PFE Pfizer	0.06%
SYK Stryker	5.90%

Compare Miscellaneous Stats

Company	Employees	Shares Outstanding	Free Float	Optionable
EW Edwards Lifesciences	15,800	586.60 million	579.03 million	Optionable
ISRG Intuitive Surgical	15,638	358.42 million	355.91 million	Optionable
PFE Pfizer	81,000	5.69 billion	5.68 billion	Optionable
SYK Stryker	53,000	381.69 million	359.17 million	Optionable

ISRG, EW, SYK, and PFE Headlines

Recent News About These Companies

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Callahan Advisors LLC Sells 1,454 Shares of Stryker Corporation (NYSE:SYK)

July 11 at 8:40 AM | marketbeat.com

Stryker Corporation (NYSE:SYK) Stock Holdings Lifted by Xponance Inc.

July 11 at 7:50 AM | marketbeat.com

Fidelis Capital Partners LLC Acquires 1,142 Shares of Stryker Corporation (NYSE:SYK)

July 11 at 7:29 AM | marketbeat.com

Mar Vista Investment Partners LLC Has $33.57 Million Position in Stryker Corporation (NYSE:SYK)

July 11 at 7:13 AM | marketbeat.com

Cerity Partners LLC Increases Stake in Stryker Corporation (NYSE:SYK)

July 11 at 6:40 AM | marketbeat.com

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July 11 at 5:07 AM | globenewswire.com

Brown Advisory Inc. Has $17.53 Million Holdings in Stryker Corporation (NYSE:SYK)

July 11 at 4:56 AM | marketbeat.com

Evercore ISI Increases Stryker (NYSE:SYK) Price Target to $415.00

July 11 at 2:23 AM | americanbankingnews.com

8,034 Shares in Stryker Corporation (NYSE:SYK) Purchased by Financial Gravity Asset Management Inc.

July 10 at 9:09 AM | marketbeat.com

Allworth Financial LP Purchases 744 Shares of Stryker Corporation (NYSE:SYK)

July 10 at 8:51 AM | marketbeat.com

Stryker Corporation (NYSE:SYK) Shares Bought by Parr Mcknight Wealth Management Group LLC

July 10 at 8:37 AM | marketbeat.com

What to Expect From Stryker's Next Quarterly Earnings Report

July 10 at 8:21 AM | finance.yahoo.com

Trek Financial LLC Has $228,000 Stake in Stryker Corporation (NYSE:SYK)

July 10 at 6:13 AM | marketbeat.com

Penserra Capital Management LLC Buys 1,132 Shares of Stryker Corporation (NYSE:SYK)

July 10 at 4:46 AM | marketbeat.com

Stryker Corporation (NYSE:SYK) Shares Sold by Bridges Investment Management Inc.

July 9 at 10:29 AM | marketbeat.com

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July 9 at 10:01 AM | marketbeat.com

Stryker Corporation (NYSE:SYK) Shares Purchased by Banque Pictet & Cie SA

July 9 at 9:43 AM | marketbeat.com

Lbp Am Sa Grows Stock Position in Stryker Corporation (NYSE:SYK)

July 9 at 9:28 AM | marketbeat.com

Rehmann Capital Advisory Group Has $22.49 Million Stake in Stryker Corporation (NYSE:SYK)

July 9 at 8:59 AM | marketbeat.com

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ISRG, EW, SYK, and PFE Company Descriptions

Edwards Lifesciences NYSE:EW

$78.07 -0.73 (-0.93%)

Closing price 03:58 PM Eastern

Extended Trading

$78.04 -0.03 (-0.04%)

As of 04:50 PM Eastern

Edwards Lifesciences Corporation provides products and technologies for structural heart disease and critical care monitoring in the United States, Europe, Japan, and internationally. It offers transcatheter heart valve replacement products for the minimally invasive replacement of aortic heart valves under the Edwards SAPIEN family of valves system; and transcatheter heart valve repair and replacement products to treat mitral and tricuspid valve diseases under the PASCAL PRECISION and Cardioband names. The company also provides surgical structural heart solutions, such as aortic surgical valve under the INSPIRIS name; INSPIRIS RESILLA aortic valve, which offers RESILIA tissue and VFit technology; KONECT RESILIA, a pre-assembled tissue valves conduit for complex combined procedures; and MITRIS RESILIA valve. In addition, it offers critical care solutions, including hemodynamic monitoring systems to measure a patient's heart function and fluid status in surgical and intensive care settings under the FloTrac, Acumen IQ sensors, ClearSight, Acumen IQ cuffs, and ForeSight names; HemoSphere, a monitoring platform that displays physiological information; and Acumen Hypotension Prediction Index software that alerts clinicians in advance of a patient developing dangerously low blood pressure. The company distributes its products through a direct sales force and independent distributors. Edwards Lifesciences Corporation was founded in 1958 and is headquartered in Irvine, California.

Intuitive Surgical NASDAQ:ISRG

$512.06 -13.99 (-2.66%)

Closing price 04:00 PM Eastern

Extended Trading

$512.38 +0.32 (+0.06%)

As of 04:50 PM Eastern

Intuitive Surgical, Inc. develops, manufactures, and markets products that enable physicians and healthcare providers to enhance the quality of and access to minimally invasive care in the United States and internationally. The company offers the da Vinci Surgical System that enables complex surgery using a minimally invasive approach; and Ion endoluminal system, which extends its commercial offerings beyond surgery into diagnostic procedures enabling minimally invasive biopsies in the lung. It also provides a suite of stapling, energy, and core instrumentation for its multi-port da Vinci surgical systems; progressive learning pathways to support the use of its technology; infrastructure of service and support specialists, a complement of services to its customers, including installation, repair, maintenance, 24/7 technical support, and proactive system health monitoring; and integrated digital capabilities providing connected offerings, streamlining performance for hospitals with program-enhancing insights. The company sells its products through direct sales organizations, such as capital and clinical sales teams. It has a collaboration agreement with FluoGuide A/S for head & neck cancer. The company was incorporated in 1995 and is headquartered in Sunnyvale, California.

Pfizer NYSE:PFE

$25.65 -0.13 (-0.50%)

Closing price 03:59 PM Eastern

Extended Trading

$25.64 0.00 (-0.02%)

As of 04:50 PM Eastern

Pfizer Inc. discovers, develops, manufactures, markets, distributes, and sells biopharmaceutical products in the United States, Europe, and internationally. The company offers medicines and vaccines in various therapeutic areas, including cardiovascular metabolic, migraine, and women's health under the Eliquis, Nurtec ODT/Vydura, Zavzpret, and the Premarin family brands; infectious diseases with unmet medical needs under the Prevnar family, Abrysvo, Nimenrix, FSME/IMMUN-TicoVac, and Trumenba brands; and COVID-19 prevention and treatment, and potential future mRNA and antiviral products under the Comirnaty and Paxlovid brands. It also provides medicines and vaccines in various therapeutic areas, such as biosimilars for chronic immune and inflammatory diseases under the Xeljanz, Enbrel, Inflectra, Litfulo, Velsipity, and Cibinqo brands; amyloidosis, hemophilia, endocrine diseases, and sickle cell disease under the Vyndaqel family, Oxbryta, BeneFIX, Somavert, Ngenla, and Genotropin brands; sterile injectable and anti-infective medicines under the Sulperazon, Medrol, Zavicefta, Zithromax, and Panzyga brands; and biologics, small molecules, immunotherapies, and biosimilars under the Ibrance, Xtandi, Inlyta, Bosulif, Mektovi, Padcev, Adcetris, Talzenna, Tukysa, Elrexfio, Tivdak, Lorbrena, and Braftovi brands. In addition, the company involved in the contract manufacturing business. It serves wholesalers, retailers, hospitals, clinics, government agencies, pharmacies, individual provider offices, retail pharmacies, and integrated delivery systems. The company has collaboration agreements with Bristol-Myers Squibb Company; Astellas Pharma US, Inc.; Merck KGaA; and BioNTech SE. Pfizer Inc. was founded in 1849 and is headquartered in New York, New York.

Stryker NYSE:SYK

$389.24 -5.53 (-1.40%)

Closing price 03:58 PM Eastern

Extended Trading

$389.37 +0.13 (+0.03%)

As of 04:50 PM Eastern

Stryker Corporation operates as a medical technology company. The company operates through two segments, MedSurg and Neurotechnology, and Orthopaedics and Spine. The Orthopaedics and Spine segment provides implants for use in total joint replacements, such as hip, knee and shoulder, and trauma and extremities surgeries. This segment also offers spinal implant products comprising cervical and thoracolumbar systems that include fixation, minimally invasive and interbody systems used in spinal injury, complex spine and degenerative therapies. The MedSurg and Neurotechnology segment offers surgical equipment, and surgical navigation systems, endoscopic and communications systems, patient handling, emergency medical equipment and intensive care disposable products, reprocessed and remanufactured medical devices, clinical communication and workflow solutions, and other medical device products that are used in various medical specialties, as well as patient and caregiver safety technologies. This segment also provides neurosurgical, neurovascular and craniomaxillofacial implant products, which include products used for minimally invasive endovascular procedures; products for brain and open skull based surgical procedures; orthobiologic and biosurgery products, such as synthetic bone grafts and vertebral augmentation products; minimally invasive products for the treatment of acute ischemic and hemorrhagic stroke; and craniomaxillofacial implant products, including cranial, maxillofacial, and chest wall devices, as well as dural substitutes and sealants. The company sells its products to doctors, hospitals, and other healthcare facilities through company-owned subsidiaries and branches, as well as third-party dealers and distributors in approximately 75 countries. Stryker Corporation was founded in 1941 and is headquartered in Portage, Michigan.

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Comparative Price Performance Over Time