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CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Ascentage Pharma Group International stock logo
AAPG
Ascentage Pharma Group International
$24.43
-5.4%
$22.34
$16.50
$26.55
$2.13BN/A61,136 shs8,579 shs
Amneal Pharmaceuticals, Inc. stock logo
AMRX
Amneal Pharmaceuticals
$7.21
-1.1%
$7.56
$6.29
$9.48
$2.26B1.171.45 million shs1.03 million shs
Mirum Pharmaceuticals, Inc. stock logo
MIRM
Mirum Pharmaceuticals
$43.73
-0.3%
$42.80
$23.83
$54.23
$2.17B0.95520,228 shs205,542 shs
Sionna Therapeutics, Inc. stock logo
SION
Sionna Therapeutics
$12.73
-2.7%
$11.70
$7.26
$25.19
$561.70MN/A188,513 shs100,965 shs
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Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Ascentage Pharma Group International stock logo
AAPG
Ascentage Pharma Group International
-2.49%+12.26%-1.83%+24.92%+2,581,999,900.00%
Amneal Pharmaceuticals, Inc. stock logo
AMRX
Amneal Pharmaceuticals
+1.82%-1.75%-2.54%-13.52%+13.02%
Mirum Pharmaceuticals, Inc. stock logo
MIRM
Mirum Pharmaceuticals
-0.30%-3.24%+7.52%-13.16%+78.70%
Sionna Therapeutics, Inc. stock logo
SION
Sionna Therapeutics
+2.83%-6.64%+7.74%-15.72%+1,307,999,900.00%
CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & Valuation
Ascentage Pharma Group International stock logo
AAPG
Ascentage Pharma Group International
N/AN/AN/AN/AN/AN/AN/AN/A
Amneal Pharmaceuticals, Inc. stock logo
AMRX
Amneal Pharmaceuticals
3.6506 of 5 stars
3.55.00.00.03.71.71.3
Mirum Pharmaceuticals, Inc. stock logo
MIRM
Mirum Pharmaceuticals
4.0757 of 5 stars
3.61.00.04.23.52.50.6
Sionna Therapeutics, Inc. stock logo
SION
Sionna Therapeutics
N/AN/AN/AN/AN/AN/AN/AN/A
CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
Ascentage Pharma Group International stock logo
AAPG
Ascentage Pharma Group International
3.00
BuyN/AN/A
Amneal Pharmaceuticals, Inc. stock logo
AMRX
Amneal Pharmaceuticals
3.00
Buy$11.5059.50% Upside
Mirum Pharmaceuticals, Inc. stock logo
MIRM
Mirum Pharmaceuticals
3.17
Buy$60.7338.87% Upside
Sionna Therapeutics, Inc. stock logo
SION
Sionna Therapeutics
3.00
Buy$38.50202.44% Upside

Current Analyst Ratings Breakdown

Latest SION, AMRX, AAPG, and MIRM Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
5/19/2025
Mirum Pharmaceuticals, Inc. stock logo
MIRM
Mirum Pharmaceuticals
HC Wainwright
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingBuy$73.00
5/13/2025
Mirum Pharmaceuticals, Inc. stock logo
MIRM
Mirum Pharmaceuticals
Raymond James
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Reiterated RatingStrong-Buy ➝ Strong-Buy
5/13/2025
Mirum Pharmaceuticals, Inc. stock logo
MIRM
Mirum Pharmaceuticals
Raymond James
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Boost Price TargetStrong-Buy ➝ Strong-Buy$73.00 ➝ $77.00
5/9/2025
Mirum Pharmaceuticals, Inc. stock logo
MIRM
Mirum Pharmaceuticals
JMP Securities
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Boost Price TargetMarket Outperform ➝ Market Outperform$74.00 ➝ $76.00
3/27/2025
Ascentage Pharma Group International stock logo
AAPG
Ascentage Pharma Group International
JPMorgan Chase & Co.
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Initiated CoverageOverweight
3/4/2025
Sionna Therapeutics, Inc. stock logo
SION
Sionna Therapeutics
TD Cowen
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Initiated CoverageBuy
3/4/2025
Sionna Therapeutics, Inc. stock logo
SION
Sionna Therapeutics
Stifel Nicolaus
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Initiated CoverageBuy$32.00
3/4/2025
Sionna Therapeutics, Inc. stock logo
SION
Sionna Therapeutics
Guggenheim
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Initiated CoverageBuy$45.00
3/3/2025
Amneal Pharmaceuticals, Inc. stock logo
AMRX
Amneal Pharmaceuticals
Barclays
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Boost Price TargetOverweight ➝ Overweight$10.00 ➝ $11.00
2/28/2025
Mirum Pharmaceuticals, Inc. stock logo
MIRM
Mirum Pharmaceuticals
HC Wainwright
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Boost Price TargetBuy ➝ Buy$66.00 ➝ $72.00
(Data available from 5/28/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)
CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
Ascentage Pharma Group International stock logo
AAPG
Ascentage Pharma Group International
$980.65M2.17N/AN/AN/A
Amneal Pharmaceuticals, Inc. stock logo
AMRX
Amneal Pharmaceuticals
$2.83B0.80$1.24 per share5.80$0.07 per share103.00
Mirum Pharmaceuticals, Inc. stock logo
MIRM
Mirum Pharmaceuticals
$379.25M5.71N/AN/A$5.33 per share8.20
Sionna Therapeutics, Inc. stock logo
SION
Sionna Therapeutics
N/AN/AN/AN/AN/AN/A
CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
Ascentage Pharma Group International stock logo
AAPG
Ascentage Pharma Group International
N/AN/A0.00N/AN/AN/AN/AN/A
Amneal Pharmaceuticals, Inc. stock logo
AMRX
Amneal Pharmaceuticals
-$83.99M-$0.04N/A12.02N/A-6.88%-346.26%4.85%N/A
Mirum Pharmaceuticals, Inc. stock logo
MIRM
Mirum Pharmaceuticals
-$163.41M-$1.61N/AN/AN/A-31.69%-41.22%-14.81%8/6/2025 (Estimated)
Sionna Therapeutics, Inc. stock logo
SION
Sionna Therapeutics
N/AN/A0.00N/AN/AN/AN/AN/A

Latest SION, AMRX, AAPG, and MIRM Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
5/14/2025Q1 2025
Mirum Pharmaceuticals, Inc. stock logo
MIRM
Mirum Pharmaceuticals
-$0.35-$0.30+$0.05-$0.30$98.47 million$111.59 million
5/12/2025Q1 2025
Sionna Therapeutics, Inc. stock logo
SION
Sionna Therapeutics
-$0.45-$0.62-$0.17-$0.62N/AN/A
5/2/2025Q1 2025
Amneal Pharmaceuticals, Inc. stock logo
AMRX
Amneal Pharmaceuticals
$0.14$0.19+$0.05$0.04$714.78 million$695.42 million
3/20/2025N/A
Sionna Therapeutics, Inc. stock logo
SION
Sionna Therapeutics
-$2.68-$3.38-$0.70-$3.38N/AN/A
2/28/2025Q4 2024
Amneal Pharmaceuticals, Inc. stock logo
AMRX
Amneal Pharmaceuticals
$0.15$0.12-$0.03-$0.10$708.21 million$730.52 million
CompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive Growth
Ascentage Pharma Group International stock logo
AAPG
Ascentage Pharma Group International
N/AN/AN/AN/AN/A
Amneal Pharmaceuticals, Inc. stock logo
AMRX
Amneal Pharmaceuticals
N/AN/AN/AN/AN/A
Mirum Pharmaceuticals, Inc. stock logo
MIRM
Mirum Pharmaceuticals
N/AN/AN/AN/AN/A
Sionna Therapeutics, Inc. stock logo
SION
Sionna Therapeutics
N/AN/AN/AN/AN/A
CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
Ascentage Pharma Group International stock logo
AAPG
Ascentage Pharma Group International
N/AN/AN/A
Amneal Pharmaceuticals, Inc. stock logo
AMRX
Amneal Pharmaceuticals
N/A
1.38
0.84
Mirum Pharmaceuticals, Inc. stock logo
MIRM
Mirum Pharmaceuticals
1.33
3.34
3.15
Sionna Therapeutics, Inc. stock logo
SION
Sionna Therapeutics
N/AN/AN/A
CompanyEmployeesShares OutstandingFree FloatOptionable
Ascentage Pharma Group International stock logo
AAPG
Ascentage Pharma Group International
60087.07 millionN/AN/A
Amneal Pharmaceuticals, Inc. stock logo
AMRX
Amneal Pharmaceuticals
7,600313.42 million255.75 millionOptionable
Mirum Pharmaceuticals, Inc. stock logo
MIRM
Mirum Pharmaceuticals
14049.54 million37.03 millionOptionable
Sionna Therapeutics, Inc. stock logo
SION
Sionna Therapeutics
3544.12 millionN/AN/A

Recent News About These Companies

2025 Power 100: Mike Cloonan
Two more biotechs join IPO waiting list
Sionna Therapeutics, Inc. (SION) Gets a Buy from TD Cowen
Sionna Therapeutics Inc.
Sionna Therapeutics sees cash runway into 2028

New MarketBeat Followers Over Time

Media Sentiment Over Time

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Ascentage Pharma Group International stock logo

Ascentage Pharma Group International NASDAQ:AAPG

$24.43 -1.39 (-5.38%)
As of 03:59 PM Eastern

Ascentage Pharma Group International Co., Ltd. is a clinical-stage biotechnology company. It engages in the development of novel therapies for cancers, hepatitis B virus, or HBV, and age-related diseases. The company was founded by Da Jun Yang, Wang Shao Meng and Ming Guo in May 2009 and is headquartered in Suzhou, China.

Amneal Pharmaceuticals stock logo

Amneal Pharmaceuticals NASDAQ:AMRX

$7.21 -0.08 (-1.10%)
Closing price 04:00 PM Eastern
Extended Trading
$7.32 +0.11 (+1.53%)
As of 07:44 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Amneal Pharmaceuticals, Inc., together with its subsidiaries, develops, manufactures, markets, and distributes generics, injectables, biosimilars, and specialty branded pharmaceutical products worldwide. The company operates through three segments: Generics, Specialty, and AvKARE. The Generics segment offers immediate and extended release oral solid, powder, liquid, sterile injectable, nasal spray, inhalation and respiratory, biosimilar, ophthalmic, film, transdermal patch, and topical products. The Specialty segment develops, promotes, sells, and distributes pharmaceutical products with focus on central nervous system disorders, including Parkinson's disease, and endocrine disorders. This segment also provides Rytary, an oral capsule formulation of carbidopa-levodopa to treat Parkinson's disease, post-encephalitic parkinsonism, and parkinsonism; Unithroid for the treatment of hypothyroidism; and IPX203, a pipeline product for Parkinson's disease. The AvKARE segment offers pharmaceuticals, medical and surgical products, and services primarily to governmental agencies, the Department of Defense, and the Department of Veterans Affairs. This segment also distributes bottle and unit dose pharmaceuticals under the AvKARE and AvPAK names; and packages and distributes pharmaceuticals and vitamins to its retail and institutional customers. It sells its products through wholesalers, distributors, hospitals, chain pharmacies, and individual pharmacies. The company was formerly known as Atlas Holdings, Inc. and changed its name to Amneal Pharmaceuticals, Inc. in 2018. Amneal Pharmaceuticals, Inc. was founded in 2002 and is headquartered in Bridgewater, New Jersey.

Mirum Pharmaceuticals stock logo

Mirum Pharmaceuticals NASDAQ:MIRM

$43.73 -0.14 (-0.32%)
Closing price 04:00 PM Eastern
Extended Trading
$46.95 +3.22 (+7.36%)
As of 05:30 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Mirum Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the development and commercialization of novel therapies for debilitating rare and orphan diseases. Its lead product candidate is LIVMARLI (maralixibat), an orally administered and minimally absorbed ileal bile acid transporter (IBAT) inhibitor that is approved for the treatment of cholestatic pruritus in patients with Alagille syndrome in the United States and internationally. The company is also involved in the commercialization of Cholbam, a cholic acid capsule, which is approved as treatment for pediatric and adult patients with bile acid synthesis disorders due to single enzyme defects and for adjunctive treatment of patients with peroxisomal disorders, including peroxisome biogenesis disorder-Zellweger spectrum disorder and Smith-Lemli-Opitz syndrome; and Chenodal, a tablet, which is approved for the treatment of radiolucent stones in the gallbladder, and under Phase 3 development for the treatment cerebrotendinous xanthomatosis. In addition, it develops Volixibat, an oral and minimally absorbed agent designed to inhibit IBAT, currently under Phase 2b clinical trial for the treatment of adult patients with cholestatic liver diseases. The company was incorporated in 2018 and is headquartered in Foster City, California.

Sionna Therapeutics stock logo

Sionna Therapeutics NASDAQ:SION

$12.73 -0.35 (-2.68%)
As of 04:00 PM Eastern

We are a clinical-stage biopharmaceutical company on a mission to revolutionize the current treatment paradigm for cystic fibrosis (“CF”) patients by developing novel medicines that normalize the function of the cystic fibrosis transmembrane conductance regulator (“CFTR”) protein to deliver clinically meaningful benefit to CF patients. Our goal is to deliver differentiated medicines for people living with CF that can restore their CFTR function to as close to normal as possible by directly stabilizing CFTR’s nucleotide-binding domain 1 (“NBD1”). Despite having long been identified as a critical component for proper CFTR function, NBD1 has been considered “undruggable,” and none of the currently approved CF therapies directly stabilizes NBD1. Worldwide revenue for approved CFTR modulators was approximately $10 billion in 2023 and is expected to grow to $15 billion by 2029. Leveraging more than a decade of our co-founders’ research on NBD1, we are advancing a pipeline of small molecules engineered to correct the defects caused by the F508del genetic mutation, which resides in the NBD1 domain. Approximately 90% of people with CF carry at least one copy of the F508del genetic mutation. We believe stabilizing NBD1 is central to unlocking dramatic improvements in clinical outcomes and quality of life for CF patients. We have employed biophysical, cell-based and virtual screening campaigns and extensive use of structural biology to guide the optimization of novel small molecule NBD1 stabilizers. We are conducting ongoing Phase 1 trials of our two highly potent NBD1 stabilizers, SION-719 and SION-451, evaluating the safety, tolerability and pharmacokinetic (“PK”) profile of single and multiple ascending doses in healthy subjects. These trials are randomized (3:1 active:placebo), doubled-blinded, placebo-controlled and are being conducted in Australia. As of January 14, 2025, five single ascending dose (“SAD”) cohorts and three multiple ascending dose (“MAD”) cohorts of SION-719 have been completed, with over 60 healthy subjects dosed, and six SAD cohorts and three MAD cohorts of SION-451 have been completed, with over 70 healthy subjects dosed. Both SION-719 and SION-451 have been generally well tolerated based on interim Phase 1 clinical data as of the data cutoff date of January 14, 2025. We have established target exposure levels for SION-719 and SION-451 to potentially provide clinically meaningful benefit, if administered as part of a dual combination or as an add-on to the current standard of care (“SOC”), based on our preclinical cystic fibrosis human bronchial epithelial (“CFHBE”) model. In these trials, we have achieved the target concentrations for SION-719 and SION-451 with single and multiple doses. We plan to continue enrolling healthy subjects in additional MAD cohorts. We are also developing a portfolio of complementary CFTR modulators designed to work synergistically with our NBD1 stabilizers to improve CFTR function, as seen in preclinical models. In July 2024, we in-licensed three clinical-stage compounds from AbbVie Global Enterprises Ltd. (“AbbVie”) to expand our portfolio of combination product opportunities, including galicaftor (SION-2222), which targets CFTR’s transmembrane domain 1 (“TMD1”), and has completed Phase 2 clinical trials. In addition, we recently completed a Phase 1 clinical trial evaluating SION-109, which targets CFTR’s intracellular loop 4 (“ICL4”) region. We plan to evaluate multiple NBD1 stabilizer candidates and complementary modulator candidates and select the most promising candidates to advance into later-stage development. Initially, we intend to evaluate the lead NBD1 stabilizer candidate in combination with the current standard of care, Trikafta, in a proof-of-concept trial. In parallel, we will determine the proprietary dual combination that we believe is optimal to advance into a later-stage clinical trial in CF patients. We were incorporated under the laws of the State of Delaware in August 2019 under the name Sling Therapeutics, Inc., and changed our name to Sionna Therapeutics, Inc. in July 2021. Our principal executive offices are located at 21 Hickory Drive, Suite 500, Waltham, MA. We have one subsidiary, Sionna Therapeutics Securities Corporation (f/k/a Sling Therapeutics Securities Corporation), formed in 2020 under the laws of the Commonwealth of Massachusetts.