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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:APLSNASDAQ:ARWRNASDAQ:MIRMNASDAQ:TSHA On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeAPLSApellis Pharmaceuticals$17.44-1.9%$19.62$16.10▼$43.76$2.19B0.732.26 million shs1.29 million shsARWRArrowhead Pharmaceuticals$15.13-1.7%$13.32$9.57▼$30.41$2.09B0.891.50 million shs1.23 million shsMIRMMirum Pharmaceuticals$44.00-0.1%$42.95$23.83▼$54.23$2.18B0.95522,623 shs164,520 shsTSHATaysha Gene Therapies$2.75-3.5%$1.83$1.05▼$4.32$563.90M0.92.90 million shs4.06 million shs2025 Gold Forecast: A Perfect Storm for DemandUnlock the timeless value of gold with our exclusive 2025 Gold Forecasting Report. Explore why gold remains the ultimate investment for safeguarding wealth against inflation, economic shifts, and global uncertainties. Whether you're planning for future generations or seeking a reliable asset in turbulent times, this report is your essential guide to making informed decisions.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceAPLSApellis Pharmaceuticals-1.91%-0.06%-0.29%-36.63%-60.00%ARWRArrowhead Pharmaceuticals-1.69%-3.69%+16.30%-23.97%-39.82%MIRMMirum Pharmaceuticals-0.11%-2.24%+11.06%-16.20%+67.81%TSHATaysha Gene Therapies-3.51%+1.85%+51.10%+70.81%-7.41%Compare MarketRank™CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & ValuationAPLSApellis Pharmaceuticals4.193 of 5 stars4.30.00.04.42.92.50.6ARWRArrowhead Pharmaceuticals3.5085 of 5 stars3.31.00.03.43.32.50.0MIRMMirum Pharmaceuticals4.0563 of 5 stars3.61.00.04.23.52.50.6TSHATaysha Gene Therapies2.9025 of 5 stars4.50.00.00.02.81.71.3Compare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceAPLSApellis Pharmaceuticals 2.62Moderate Buy$39.89128.75% UpsideARWRArrowhead Pharmaceuticals 2.67Moderate Buy$42.13178.42% UpsideMIRMMirum Pharmaceuticals 3.17Buy$60.7338.02% UpsideTSHATaysha Gene Therapies 3.00Buy$6.57138.96% UpsideCurrent Analyst Ratings BreakdownLatest TSHA, MIRM, APLS, and ARWR Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails5/22/2025APLSApellis PharmaceuticalsCitigroupSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetBuy ➝ Buy$49.00 ➝ $41.005/20/2025ARWRArrowhead PharmaceuticalsHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$80.00 ➝ $80.005/19/2025MIRMMirum PharmaceuticalsHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy$73.005/16/2025TSHATaysha Gene TherapiesCanaccord Genuity GroupSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetBuy ➝ Buy$8.00 ➝ $9.005/14/2025APLSApellis PharmaceuticalsMizuhoSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetNeutral ➝ Neutral$30.00 ➝ $20.005/13/2025MIRMMirum PharmaceuticalsRaymond JamesSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingStrong-Buy ➝ Strong-Buy5/13/2025ARWRArrowhead PharmaceuticalsCitigroupSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetNeutral ➝ Neutral$21.00 ➝ $17.005/13/2025ARWRArrowhead PharmaceuticalsChardan CapitalSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$60.00 ➝ $60.005/13/2025MIRMMirum PharmaceuticalsRaymond JamesSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetStrong-Buy ➝ Strong-Buy$73.00 ➝ $77.005/9/2025APLSApellis PharmaceuticalsRaymond JamesSubscribe to MarketBeat All Access for the recommendation accuracy ratingDowngradeStrong-Buy ➝ Outperform$75.00 ➝ $52.005/9/2025APLSApellis PharmaceuticalsBank of AmericaSubscribe to MarketBeat All Access for the recommendation accuracy ratingDowngradeBuy ➝ Neutral$41.00 ➝ $23.00(Data available from 5/24/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookAPLSApellis Pharmaceuticals$775.84M2.83N/AN/A$1.64 per share10.63ARWRArrowhead Pharmaceuticals$545.21M3.83N/AN/A$1.54 per share9.82MIRMMirum Pharmaceuticals$379.25M5.75N/AN/A$5.33 per share8.26TSHATaysha Gene Therapies$8.33M67.67N/AN/A$0.40 per share6.88Compare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateAPLSApellis Pharmaceuticals-$528.63M-$1.79N/AN/AN/A-34.97%-103.11%-28.96%8/7/2025 (Estimated)ARWRArrowhead Pharmaceuticals-$599.49M-$1.40N/AN/AN/AN/A-236.60%-64.09%N/AMIRMMirum Pharmaceuticals-$163.41M-$1.61N/AN/AN/A-31.69%-41.22%-14.81%8/6/2025 (Estimated)TSHATaysha Gene Therapies-$111.57M-$0.344.37N/AN/A-229.67%-106.36%-49.16%8/11/2025 (Estimated)Latest TSHA, MIRM, APLS, and ARWR EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails5/15/2025Q1 2025TSHATaysha Gene Therapies-$0.08-$0.08N/A-$0.08$1.48 million$2.30 million5/14/2025Q1 2025MIRMMirum Pharmaceuticals-$0.35-$0.30+$0.05-$0.30$98.47 million$111.59 million5/12/2025Q2 2025ARWRArrowhead Pharmaceuticals-$0.06$2.75+$2.81$2.75$116.27 million$542.71 million5/7/2025Q1 2025APLSApellis Pharmaceuticals-$0.36-$0.74-$0.38-$0.74$197.61 million$149.90 million2/28/2025Q4 2024APLSApellis Pharmaceuticals-$0.37-$0.29+$0.08-$0.29$197.92 million$212.50 million2/26/2025Q4 2024MIRMMirum Pharmaceuticals-$0.27-$0.49-$0.22-$0.49$96.64 million$99.41 million2/26/2025Q4 2024TSHATaysha Gene Therapies-$0.08-$0.07+$0.01-$0.07$2.05 million$2.02 millionCompare DividendsCompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive GrowthAPLSApellis PharmaceuticalsN/AN/AN/AN/AN/AARWRArrowhead PharmaceuticalsN/AN/AN/AN/AN/AMIRMMirum PharmaceuticalsN/AN/AN/AN/AN/ATSHATaysha Gene TherapiesN/AN/AN/AN/AN/ACompare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioAPLSApellis Pharmaceuticals1.914.363.73ARWRArrowhead Pharmaceuticals7.276.096.09MIRMMirum Pharmaceuticals1.333.343.15TSHATaysha Gene Therapies0.485.515.51Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipAPLSApellis Pharmaceuticals96.29%ARWRArrowhead Pharmaceuticals62.61%MIRMMirum PharmaceuticalsN/ATSHATaysha Gene Therapies77.70%Insider OwnershipCompanyInsider OwnershipAPLSApellis Pharmaceuticals6.50%ARWRArrowhead Pharmaceuticals4.30%MIRMMirum Pharmaceuticals14.36%TSHATaysha Gene Therapies2.70%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableAPLSApellis Pharmaceuticals770125.68 million115.93 millionOptionableARWRArrowhead Pharmaceuticals400138.10 million120.68 millionOptionableMIRMMirum Pharmaceuticals14049.54 million37.03 millionOptionableTSHATaysha Gene Therapies180205.06 million199.41 millionOptionableTSHA, MIRM, APLS, and ARWR HeadlinesRecent News About These CompaniesFY2025 EPS Estimates for TSHA Increased by Cantor FitzgeraldMay 23 at 8:29 AM | marketbeat.comCantor Fitzgerald Has Positive View of TSHA FY2025 EarningsMay 23 at 2:43 AM | americanbankingnews.comVR Adviser LLC Sells 5,774,820 Shares of Taysha Gene Therapies, Inc. (NASDAQ:TSHA)May 22 at 6:53 AM | marketbeat.comRTW Investments LP Has $15 Million Stock Holdings in Taysha Gene Therapies, Inc. (NASDAQ:TSHA)May 18, 2025 | marketbeat.comTaysha Gene Therapies (NASDAQ:TSHA) Stock Price Up 6.1% Following Analyst UpgradeMay 17, 2025 | americanbankingnews.comTaysha Gene Therapies, Inc. (NASDAQ:TSHA) Q1 2025 Earnings Call TranscriptMay 16, 2025 | msn.comQ1 2025 Taysha Gene Therapies Inc Earnings CallMay 16, 2025 | finance.yahoo.comTaysha Gene Therapies Inc (TSHA) Q1 2025 Earnings Call Highlights: Promising Clinical Progress ...May 16, 2025 | finance.yahoo.comTaysha Gene Therapies Advances in Rett Syndrome TrialsMay 16, 2025 | tipranks.comTaysha outlines expedited pivotal trial start for TSHA-102 following FDA alignmentMay 15, 2025 | msn.comTaysha Gene Therapies, Inc. (TSHA) Q1 2025 Earnings Call TranscriptMay 15, 2025 | seekingalpha.comTaysha Gene Therapies, Inc. (TSHA) Reports Q1 Loss, Tops Revenue EstimatesMay 15, 2025 | zacks.comTaysha Gene Therapies Reports First Quarter 2025 Financial Results and Provides Corporate UpdateMay 15, 2025 | globenewswire.comTaysha Gene Therapies, Inc. (NASDAQ:TSHA) Shares Bought by Octagon Capital Advisors LPMay 15, 2025 | marketbeat.comGranahan Investment Management LLC Buys 496,482 Shares of Taysha Gene Therapies, Inc. (NASDAQ:TSHA)May 13, 2025 | marketbeat.comDAFNA Capital Management LLC Makes New $904,000 Investment in Taysha Gene Therapies, Inc. (NASDAQ:TSHA)May 10, 2025 | marketbeat.comTaysha Gene Therapies to Release First Quarter 2025 Financial Results and Host Conference Call and Webcast on May 15May 8, 2025 | globenewswire.comTaysha Gene Therapies (TSHA) to Release Quarterly Earnings on TuesdayMay 8, 2025 | marketbeat.comMarshall Wace LLP Lowers Stock Position in Taysha Gene Therapies, Inc. (NASDAQ:TSHA)May 8, 2025 | marketbeat.comWill Taysha Gene Therapies, Inc. (TSHA) Report Negative Q1 Earnings? What You Should KnowMay 6, 2025 | zacks.comTaysha Gene Therapies (NASDAQ:TSHA) Stock Price Up 9.3% - What's Next?May 5, 2025 | marketbeat.comNew MarketBeat Followers Over TimeMedia Sentiment Over TimeTSHA, MIRM, APLS, and ARWR Company DescriptionsApellis Pharmaceuticals NASDAQ:APLS$17.44 -0.34 (-1.91%) Closing price 05/23/2025 04:00 PM EasternExtended Trading$17.55 +0.11 (+0.61%) As of 05/23/2025 06:50 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Apellis Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of therapeutic compounds through the inhibition of the complement system for autoimmune and inflammatory diseases. It offers EMPAVELI for the treatment of paroxysmal nocturnal hemoglobinuria, C3 glomerulopathy and immune complex membranoproliferative glomerulonephritis, and hematopoietic stem cell transplantation-associated thrombotic microangiopathy; and SYFOVRE for treating geographic atrophy secondary to age-related macular degeneration and geographic atrophy (GA). The company also develops APL-3007, a small interfering RNA, or siRNA, which is in a Phase 1 clinical trial, as well as an oral complement inhibitor that is in preclinical development. It has a collaboration and license agreement with Swedish Orphan Biovitrum AB (publ) for development and commercialization of pegcetacoplan; and a collaboration with Beam Therapeutics Inc. focused on the use of Beam's base editing technology to discover new treatments for complement-driven diseases. The company was incorporated in 2009 and is based in Waltham, Massachusetts.Arrowhead Pharmaceuticals NASDAQ:ARWR$15.13 -0.26 (-1.69%) Closing price 05/23/2025 04:00 PM EasternExtended Trading$15.32 +0.18 (+1.22%) As of 05/23/2025 05:57 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Arrowhead Pharmaceuticals, Inc. develops medicines for the treatment of intractable diseases in the United States. The company's products in pipeline includes Plozasiran, which is in Phase 2b and one Phase 3 clinical trial to treat hypertriglyceridemia, mixed dyslipidemia, and chylomicronemia syndrome; Zodasiran that is in Phase 2b clinical trial for the treatment of dyslipidemia and hypertriglyceridemia; ARO-PNPLA3, which is in Phase 1 clinical trial to treat patients with non-alcoholic steatohepatitis; ARO-RAGE that is in Phase 1/2a clinical trial to treat inflammatory pulmonary conditions; and ARO-MUC5AC, which is in Phase 1/2a clinical trial to treat muco-obstructive pulmonary diseases. It also develops ARO-MMP7 that is in Phase 1/2a clinical trial for treatment of idiopathic pulmonary fibrosis; ARO-DUX4 for the treatment of facioscapulohumeral muscular dystrophy; ARO-SOD1 for the potential treatment of amyotrophic lateral sclerosis; and ARO-C3, which is in Phase 1/2a clinical trial for the treatment of patients with various complement mediated or complement associated renal diseases. In addition, the company is involved in the development of JNJ-3989, which is in Phase 2 clinical trial to treat chronic hepatitis B virus infection; Olpasiran that is in Phase 3 clinical trial to reduce the production of apolipoprotein A; GSK-4532990 that is in phase 2 clinical trial to treat liver diseases; HZN-457, which is in phase 1 clinical trial to treat uncontrolled gout; and Fazirsiran that is in Phase 3 clinical trial for the treatment for liver disease associated with alpha-1 antitrypsin deficiency. Arrowhead Pharmaceuticals, Inc. has license and research collaboration agreements with Janssen Pharmaceuticals, Inc.; Takeda Pharmaceutical Company Limited; Horizon Therapeutics Ireland DAC; Amgen Inc.; and Glaxosmithkline Intellectual Property (No. 3) Limited. The company was founded in 2003 and is headquartered in Pasadena, California.Mirum Pharmaceuticals NASDAQ:MIRM$44.00 -0.05 (-0.11%) Closing price 05/23/2025 04:00 PM EasternExtended Trading$43.99 -0.01 (-0.02%) As of 05/23/2025 07:51 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Mirum Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the development and commercialization of novel therapies for debilitating rare and orphan diseases. Its lead product candidate is LIVMARLI (maralixibat), an orally administered and minimally absorbed ileal bile acid transporter (IBAT) inhibitor that is approved for the treatment of cholestatic pruritus in patients with Alagille syndrome in the United States and internationally. The company is also involved in the commercialization of Cholbam, a cholic acid capsule, which is approved as treatment for pediatric and adult patients with bile acid synthesis disorders due to single enzyme defects and for adjunctive treatment of patients with peroxisomal disorders, including peroxisome biogenesis disorder-Zellweger spectrum disorder and Smith-Lemli-Opitz syndrome; and Chenodal, a tablet, which is approved for the treatment of radiolucent stones in the gallbladder, and under Phase 3 development for the treatment cerebrotendinous xanthomatosis. In addition, it develops Volixibat, an oral and minimally absorbed agent designed to inhibit IBAT, currently under Phase 2b clinical trial for the treatment of adult patients with cholestatic liver diseases. The company was incorporated in 2018 and is headquartered in Foster City, California.Taysha Gene Therapies NASDAQ:TSHA$2.75 -0.10 (-3.51%) Closing price 05/23/2025 04:00 PM EasternExtended Trading$2.75 0.00 (0.00%) As of 05/23/2025 05:22 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Taysha Gene Therapies, Inc., a gene therapy company, focuses on developing and commercializing adeno-associated virus-based gene therapies for the treatment of monogenic diseases of the central nervous system. It primarily develops TSHA-120 for the treatment of giant axonal neuropathy; TSHA-102 for the treatment of Rett syndrome; TSHA-121 for the treatment of CLN7 disease; TSHA-118 for the treatment of CLN1 disease; TSHA-105 for the treatment of for SLC13A5 deficiency; TSHA-113 for the treatment of tauopathies; TSHA-106 for the treatment of angelman syndrome; TSHA-114 for the treatment of fragile X syndrome; and TSHA-101 for the treatment of GM2 gangliosidosis. Taysha Gene Therapies, Inc. has a strategic partnership with The University of Texas Southwestern Medical Center. Taysha Gene Therapies, Inc. was incorporated in 2019 and is headquartered in Dallas, Texas. 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