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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:CRSPNASDAQ:VRTX On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeCRSPCRISPR Therapeutics$36.78-1.2%$36.80$30.04▼$67.88$3.18B1.881.70 million shs2.72 million shsVRTXVertex Pharmaceuticals$447.09+0.4%$472.28$377.85▼$519.88$114.81B0.511.42 million shs877,461 shsFree Today: Your Guide to Smarter Options TradesLearn the basics of options trading and how to use them to boost returns and manage risk with this free report from MarketBeat. Click the link below to get your free copy.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceCRSPCRISPR Therapeutics-0.93%+0.62%-1.74%-14.67%-32.13%VRTXVertex Pharmaceuticals-0.20%+2.25%-10.35%-6.20%-0.40%Compare MarketRank™CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & ValuationCRSPCRISPR Therapeutics3.0048 of 5 stars4.31.00.00.03.02.50.6VRTXVertex Pharmaceuticals4.4372 of 5 stars3.33.00.03.34.22.51.3Compare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceCRSPCRISPR Therapeutics 2.50Moderate Buy$71.7595.08% UpsideVRTXVertex Pharmaceuticals 2.57Moderate Buy$515.0415.20% UpsideCurrent Analyst Ratings BreakdownLatest VRTX and CRSP Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails5/23/2025VRTXVertex PharmaceuticalsErste Group BankSubscribe to MarketBeat All Access for the recommendation accuracy ratingDowngradeStrong-Buy ➝ Hold5/21/2025CRSPCRISPR TherapeuticsJMP SecuritiesSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingMarket Outperform ➝ Market Outperform$86.00 ➝ $86.005/20/2025CRSPCRISPR TherapeuticsNeedham & Company LLCSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$81.00 ➝ $81.005/20/2025CRSPCRISPR TherapeuticsHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$65.00 ➝ $65.005/9/2025CRSPCRISPR TherapeuticsBarclaysSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetEqual Weight ➝ Equal Weight$56.00 ➝ $42.005/8/2025CRSPCRISPR TherapeuticsThe Goldman Sachs GroupSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetNeutral ➝ Neutral$53.00 ➝ $47.005/7/2025CRSPCRISPR TherapeuticsNeedham & Company LLCSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetBuy ➝ Buy$84.00 ➝ $81.005/7/2025CRSPCRISPR TherapeuticsChardan CapitalSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetBuy ➝ Buy$84.00 ➝ $82.005/7/2025VRTXVertex PharmaceuticalsWolfe ResearchSubscribe to MarketBeat All Access for the recommendation accuracy ratingDowngradeOutperform ➝ Peer Perform5/6/2025VRTXVertex PharmaceuticalsThe Goldman Sachs GroupSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy5/6/2025VRTXVertex PharmaceuticalsLeerink PartnrsSubscribe to MarketBeat All Access for the recommendation accuracy ratingDowngradeStrong-Buy ➝ Hold(Data available from 5/29/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookCRSPCRISPR Therapeutics$35M90.76N/AN/A$22.52 per share1.63VRTXVertex Pharmaceuticals$11.10B10.34N/AN/A$63.90 per share7.00Compare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateCRSPCRISPR Therapeutics-$366.25M-$4.52N/AN/AN/A-981.54%-18.46%-15.79%8/4/2025 (Estimated)VRTXVertex Pharmaceuticals-$535.60M-$3.92N/A25.532.11-4.86%-2.02%-1.49%8/7/2025 (Estimated)Latest VRTX and CRSP EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails5/6/2025Q1 2025CRSPCRISPR Therapeutics-$1.27-$1.58-$0.31-$1.58N/AN/A5/5/2025Q1 2025VRTXVertex Pharmaceuticals$4.29$4.06-$0.23$2.49$2.85 billion$2.77 billionCompare DividendsCompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive GrowthCRSPCRISPR TherapeuticsN/AN/AN/AN/AN/AVRTXVertex PharmaceuticalsN/AN/AN/AN/AN/ACompare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioCRSPCRISPR TherapeuticsN/A22.0722.07VRTXVertex Pharmaceuticals0.012.692.35Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipCRSPCRISPR Therapeutics69.20%VRTXVertex Pharmaceuticals90.96%Insider OwnershipCompanyInsider OwnershipCRSPCRISPR Therapeutics4.10%VRTXVertex Pharmaceuticals0.20%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableCRSPCRISPR Therapeutics47386.36 million82.26 millionOptionableVRTXVertex Pharmaceuticals4,800256.80 million256.28 millionOptionableVRTX and CRSP HeadlinesRecent News About These CompaniesDSG Capital Advisors LLC Buys New Shares in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)May 29 at 7:48 AM | marketbeat.com111 Capital Makes New Investment in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)May 29 at 7:39 AM | marketbeat.comLansforsakringar Fondforvaltning AB publ Takes $58.27 Million Position in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)May 29 at 7:00 AM | marketbeat.comPKO Investment Management Joint Stock Co Invests $3.06 Million in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)May 29 at 6:52 AM | marketbeat.comWealthedge Investment Advisors LLC Makes New Investment in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)May 29 at 6:34 AM | marketbeat.comLighthouse Financial LLC Purchases Shares of 3,705 Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)May 29 at 6:26 AM | marketbeat.comIronOak Wealth LLC. Invests $623,000 in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)May 29 at 5:54 AM | marketbeat.comBridgePort Financial Solutions LLC Makes New Investment in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)May 29 at 5:44 AM | marketbeat.comTFR Capital LLC. Makes New $1.84 Million Investment in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)May 28 at 7:26 AM | marketbeat.comEmployees Retirement System of Texas Grows Position in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)May 28 at 7:21 AM | marketbeat.comJefferies Financial Group Inc. Sells 18,659 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)May 28 at 7:02 AM | marketbeat.comSiemens Fonds Invest GmbH Sells 1,648 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)May 28 at 6:47 AM | marketbeat.comUniversal Beteiligungs und Servicegesellschaft mbH Takes Position in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)May 28 at 6:13 AM | marketbeat.comB. Riley Wealth Advisors Inc. Has $2.87 Million Position in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)May 28 at 6:00 AM | marketbeat.com892 Shares in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) Acquired by Armis Advisers LLCMay 28 at 6:00 AM | marketbeat.comVertex Pharmaceuticals Incorporated (NASDAQ:VRTX) Shares Acquired by Great Valley Advisor Group Inc.May 28 at 5:40 AM | marketbeat.comIntegrated Advisors Network LLC Has $1.24 Million Holdings in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)May 28 at 5:36 AM | marketbeat.comMackenzie Financial Corp Lowers Position in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)May 28 at 5:15 AM | marketbeat.comToronto Dominion Bank Decreases Stake in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)May 28 at 5:07 AM | marketbeat.comPolar Asset Management Partners Inc. Invests $22.95 Million in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)May 27 at 7:07 AM | marketbeat.com3 Top Growth Stocks to Buy in the Second Half of 2025May 26 at 4:46 AM | fool.comNew MarketBeat Followers Over TimeMedia Sentiment Over TimeTop HeadlinesView All HeadlinesBullish NVIDIA Market Set to Surge 50% Ahead of Q1 EarningsBy Thomas Hughes | May 27, 2025View Bullish NVIDIA Market Set to Surge 50% Ahead of Q1 EarningsNavitas Soars on NVIDIA Deal: Breaking Down Its Tech and OutlookBy Leo Miller | May 27, 2025View Navitas Soars on NVIDIA Deal: Breaking Down Its Tech and OutlookQualcomm Is 5x Cheaper Than AMD, But Won’t Be for LongBy Sam Quirke | May 13, 2025View Qualcomm Is 5x Cheaper Than AMD, But Won’t Be for LongWhy D-Wave's Project With Davidson Is a Game-Changer For QuantumBy Nathan Reiff | April 30, 2025View Why D-Wave's Project With Davidson Is a Game-Changer For QuantumCRSPR Stock Could Be Ready to Deliver on Its Massive PromiseBy Chris Markoch | May 16, 2025View CRSPR Stock Could Be Ready to Deliver on Its Massive PromiseVRTX and CRSP Company DescriptionsCRISPR Therapeutics NASDAQ:CRSP$36.78 -0.44 (-1.18%) Closing price 04:00 PM EasternExtended Trading$37.09 +0.31 (+0.84%) As of 04:39 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.CRISPR Therapeutics is a gene-editing company focused on developing transformative gene-based medicines for serious diseases using its proprietary CRISPR/Cas9 platform. CRISPR/Cas9 is a revolutionary gene-editing technology that allows for precise, directed changes to genomic DNA. CRISPR Therapeutics has established a portfolio of therapeutic programs across a broad range of disease areas including hemoglobinopathies, oncology, regenerative medicine and rare diseases. To accelerate and expand its efforts, CRISPR Therapeutics has established strategic collaborations with companies including Bayer, Vertex Pharmaceuticals and ViaCyte, Inc. CRISPR Therapeutics AG is headquartered in Zug, Switzerland, with its wholly-owned U.S. subsidiary, CRISPR Therapeutics, Inc., and R&D operations based in Cambridge, Massachusetts, and business offices in San Francisco, California and London, United Kingdom. For more information, please visit www.crisprtx.com.Vertex Pharmaceuticals NASDAQ:VRTX$447.09 +1.99 (+0.45%) Closing price 04:00 PM EasternExtended Trading$447.20 +0.12 (+0.03%) As of 04:35 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Vertex Pharmaceuticals Incorporated, a biotechnology company, engages in developing and commercializing therapies for treating cystic fibrosis (CF). It markets TRIKAFTA/KAFTRIO for people with CF with at least one F508del mutation for 2 years of age or older; SYMDEKO/SYMKEVI for people with CF for 6 years of age or older; ORKAMBI for CF patients 1 year or older; and KALYDECO for the treatment of patients with 1 year or older who have CF with ivacaftor. The company's pipeline includes VX-522, a CFTR mRNA therapeutic designed to treat the underlying cause of CF, which is in Phase 1 clinical trial; VX-548, a non-opioid medicine for the treatment of acute and neuropathic pain which is in Phase 3 clinical trial; Exa-cel, for the treatment of sickle cell disease and transfusion-dependent beta thalassemia which is in Phase 2/3 clinical trial. In addition, it provides inaxaplin for the treatment of APOL1-mediated focal segmental glomerulosclerosis and co-morbidities, such as hypertension which is in single Phase 2/3; VX- 880 and VX-264, treatment for Type 1 Diabetes which is in Phase 1/2 clinical trial; VX-970, which is in Phase 2 clinical trial for the treatment of cancer; and VX-803 and VX-984 for treatment of cancer in Phase 1 clinical trial. Further, it sells the products to specialty pharmacy and specialty distributors in the United States, as well as retail pharmacies, hospitals, and clinics. Additionally, the company has collaborations with CRISPR Therapeutics AG.; Moderna, Inc.; Entrada Therapeutics, Inc.; Arbor Biotechnologies, Inc.; Mammoth Biosciences, Inc.; and Verve Therapeutics., as well as collaborations with Tevard Biosciences to develop novel tRNA-based therapies for duchenne muscular dystrophy. Vertex Pharmaceuticals Incorporated was founded in 1989 and is headquartered in Boston, Massachusetts. 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