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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:ACADNASDAQ:ARWRNASDAQ:ASNDNASDAQ:IONSNASDAQ:UTHR On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeACADACADIA Pharmaceuticals$20.95-1.4%$20.14$13.40▼$25.23$3.51B0.641.97 million shs916,956 shsARWRArrowhead Pharmaceuticals$16.78-0.7%$15.38$9.57▼$30.41$2.32B0.931.55 million shs800,545 shsASNDAscendis Pharma A/S$174.07+0.6%$167.48$111.09▼$183.00$10.64B0.38500,084 shs157,816 shsIONSIonis Pharmaceuticals$42.98-1.4%$34.97$23.95▼$52.34$6.84B0.231.60 million shs1.34 million shsUTHRUnited Therapeutics$294.57-0.2%$301.15$266.98▼$417.82$13.29B0.53445,700 shs284,212 shs2025 Gold Forecast: A Perfect Storm for DemandUnlock the timeless value of gold with our exclusive 2025 Gold Forecasting Report. Explore why gold remains the ultimate investment for safeguarding wealth against inflation, economic shifts, and global uncertainties. Whether you're planning for future generations or seeking a reliable asset in turbulent times, this report is your essential guide to making informed decisions.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceACADACADIA Pharmaceuticals-1.37%-5.67%-4.69%+36.22%+34.38%ARWRArrowhead Pharmaceuticals-0.71%+4.42%+1.02%+57.12%-33.07%ASNDAscendis Pharma A/S+0.56%+0.65%-0.19%+22.01%+29.73%IONSIonis Pharmaceuticals-1.40%+8.04%+23.65%+58.66%-5.75%UTHRUnited Therapeutics-0.22%+3.69%-9.14%+0.72%-5.30%Compare MarketRank™CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & ValuationACADACADIA Pharmaceuticals4.6936 of 5 stars4.43.00.00.03.14.22.5ARWRArrowhead Pharmaceuticals3.9979 of 5 stars3.42.00.03.43.12.50.0ASNDAscendis Pharma A/S3.6726 of 5 stars4.53.00.00.02.81.70.6IONSIonis Pharmaceuticals4.6688 of 5 stars4.42.00.03.03.23.30.6UTHRUnited Therapeutics4.9955 of 5 stars4.35.00.04.63.43.32.5Compare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceACADACADIA Pharmaceuticals 2.71Moderate Buy$27.8833.05% UpsideARWRArrowhead Pharmaceuticals 2.75Moderate Buy$43.71160.51% UpsideASNDAscendis Pharma A/S 3.00Buy$220.6726.77% UpsideIONSIonis Pharmaceuticals 2.78Moderate Buy$58.2535.53% UpsideUTHRUnited Therapeutics 2.69Moderate Buy$386.1531.09% UpsideCurrent Analyst Ratings BreakdownLatest ASND, ARWR, IONS, ACAD, and UTHR Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails7/3/2025ASNDAscendis Pharma A/SMorgan StanleySubscribe to MarketBeat All Access for the recommendation accuracy ratingInitiated CoverageOverweight$250.007/1/2025IONSIonis PharmaceuticalsBarclaysSubscribe to MarketBeat All Access for the recommendation accuracy ratingUpgradeEqual Weight ➝ Overweight$51.00 ➝ $57.006/30/2025UTHRUnited TherapeuticsUBS GroupSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetBuy ➝ Buy$410.00 ➝ $385.006/26/2025ACADACADIA PharmaceuticalsOppenheimerSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingMarket Perform ➝ Market Perform$19.00 ➝ $22.006/26/2025ACADACADIA PharmaceuticalsJMP SecuritiesSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingMarket Outperform ➝ Market Outperform$37.006/26/2025ACADACADIA PharmaceuticalsNeedham & Company LLCSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$30.006/26/2025ACADACADIA PharmaceuticalsHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$32.006/26/2025IONSIonis PharmaceuticalsHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$50.006/23/2025ACADACADIA PharmaceuticalsRoyal Bank Of CanadaSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetOutperform ➝ Outperform$26.00 ➝ $38.006/13/2025ASNDAscendis Pharma A/SOppenheimerSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingOutperform ➝ Outperform$215.00 ➝ $224.006/12/2025IONSIonis PharmaceuticalsJPMorgan Chase & Co.Subscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetNeutral ➝ Neutral$45.00 ➝ $48.00(Data available from 7/4/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookACADACADIA Pharmaceuticals$957.80M3.66$0.70 per share30.13$4.40 per share4.76ARWRArrowhead Pharmaceuticals$545.21M4.25N/AN/A$1.54 per share10.90ASNDAscendis Pharma A/S$393.54M27.04N/AN/A($1.88) per share-92.59IONSIonis Pharmaceuticals$717.25M9.54N/AN/A$3.73 per share11.52UTHRUnited Therapeutics$2.88B4.62$28.32 per share10.40$144.34 per share2.04Compare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateACADACADIA Pharmaceuticals$226.45M$1.3715.2927.574.5822.97%17.46%10.75%8/5/2025 (Estimated)ARWRArrowhead Pharmaceuticals-$599.49M-$1.40N/AN/A19.88N/A-45.33%-12.49%8/6/2025 (Estimated)ASNDAscendis Pharma A/S-$409.12M-$6.28N/A725.29N/A-93.22%N/A-33.29%9/2/2025 (Estimated)IONSIonis Pharmaceuticals-$453.90M-$2.99N/AN/AN/A-63.65%-91.85%-15.77%7/30/2025 (Estimated)UTHRUnited Therapeutics$1.20B$25.0611.7510.726.4640.44%19.33%16.73%7/30/2025 (Estimated)Latest ASND, ARWR, IONS, ACAD, and UTHR EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails7/30/2025Q2 2025UTHRUnited Therapeutics$6.89N/AN/AN/A$802.13 millionN/A5/12/2025Q2 2025ARWRArrowhead Pharmaceuticals-$0.06$2.75+$2.81$2.75$116.27 million$542.71 million5/7/2025Q1 2025ACADACADIA Pharmaceuticals$0.10$0.11+$0.01$0.11$239.32 million$244.32 million5/1/2025Q1 2025ASNDAscendis Pharma A/S-$1.56-$1.66-$0.10-$1.66$98.56 million$123.97 million4/30/2025Q1 2025IONSIonis Pharmaceuticals-$1.07-$0.93+$0.14-$0.93$144.31 million$132.00 million4/30/2025Q1 2025UTHRUnited Therapeutics$6.29$6.63+$0.34$6.63$726.82 million$794.40 millionCompare DividendsCompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive GrowthACADACADIA PharmaceuticalsN/AN/AN/AN/AN/AARWRArrowhead PharmaceuticalsN/AN/AN/AN/AN/AASNDAscendis Pharma A/SN/AN/AN/AN/AN/AIONSIonis PharmaceuticalsN/AN/AN/AN/AN/AUTHRUnited TherapeuticsN/AN/AN/AN/AN/ACompare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioACADACADIA PharmaceuticalsN/A2.882.80ARWRArrowhead Pharmaceuticals0.315.155.15ASNDAscendis Pharma A/SN/A1.040.71IONSIonis Pharmaceuticals2.639.669.62UTHRUnited TherapeuticsN/A5.465.23Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipACADACADIA Pharmaceuticals96.71%ARWRArrowhead Pharmaceuticals62.61%ASNDAscendis Pharma A/SN/AIONSIonis Pharmaceuticals93.86%UTHRUnited Therapeutics94.08%Insider OwnershipCompanyInsider OwnershipACADACADIA Pharmaceuticals26.50%ARWRArrowhead Pharmaceuticals4.30%ASNDAscendis Pharma A/S40.00%IONSIonis Pharmaceuticals2.60%UTHRUnited Therapeutics10.30%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableACADACADIA Pharmaceuticals510167.36 million123.01 millionOptionableARWRArrowhead Pharmaceuticals400138.10 million132.16 millionOptionableASNDAscendis Pharma A/S1,01761.13 million36.68 millionOptionableIONSIonis Pharmaceuticals1,069159.16 million155.02 millionOptionableUTHRUnited Therapeutics1,30545.11 million40.46 millionOptionableASND, ARWR, IONS, ACAD, and UTHR HeadlinesRecent News About These CompaniesWill United Therapeutics (UTHR) Beat Estimates Again in Its Next Earnings Report?July 4 at 1:11 PM | zacks.comNew York State Teachers Retirement System Lowers Holdings in United Therapeutics Corporation (NASDAQ:UTHR)July 3 at 4:34 AM | marketbeat.comUnited Therapeutics Corporation (NASDAQ:UTHR) Holdings Raised by Sumitomo Mitsui Trust Group Inc.July 3 at 4:24 AM | marketbeat.comWhy Investors Need to Take Advantage of These 2 Medical Stocks NowJuly 2 at 9:56 AM | zacks.comAmalgamated Bank Trims Position in United Therapeutics Corporation (NASDAQ:UTHR)July 2 at 5:16 AM | marketbeat.comAllspring Global Investments Holdings LLC Decreases Stock Holdings in United Therapeutics Corporation (NASDAQ:UTHR)July 2 at 4:31 AM | marketbeat.comWealth Enhancement Advisory Services LLC Sells 2,214 Shares of United Therapeutics Corporation (NASDAQ:UTHR)July 2 at 3:16 AM | marketbeat.comDiversified Trust Co Purchases 1,074 Shares of United Therapeutics Corporation (NASDAQ:UTHR)July 1 at 4:26 AM | marketbeat.comBessemer Group Inc. Cuts Stock Position in United Therapeutics Corporation (NASDAQ:UTHR)July 1 at 3:56 AM | marketbeat.comCambridge Investment Research Advisors Inc. Purchases 2,211 Shares of United Therapeutics Corporation (NASDAQ:UTHR)July 1 at 3:37 AM | marketbeat.comUBS Group Cuts United Therapeutics (NASDAQ:UTHR) Price Target to $385.00June 30, 2025 | marketbeat.comUnited Therapeutics’ Inhaled Treprostinil Study: A Potential Game-Changer for IPF TreatmentJune 30, 2025 | tipranks.comKBC Group NV Has $33.63 Million Position in United Therapeutics Corporation (NASDAQ:UTHR)June 30, 2025 | marketbeat.comPaul A. Mahon Sells 11,000 Shares of United Therapeutics Corporation (NASDAQ:UTHR) StockJune 29, 2025 | americanbankingnews.comUnited Therapeutics Corporation (UTHR) - Yahoo FinanceJune 28, 2025 | finance.yahoo.comUnited Therapeutics Corporation (NASDAQ:UTHR) EVP Paul A. Mahon Sells 11,000 SharesJune 28, 2025 | insidertrades.comUnited Therapeutics Announces World’s First Bioengineered External Liver Treatment in Clinical StudyJune 28, 2025 | msn.comUTHR United Therapeutics Corporation - Seeking AlphaJune 27, 2025 | seekingalpha.comInsider Selling: United Therapeutics Corporation (NASDAQ:UTHR) EVP Sells 11,000 Shares of StockJune 27, 2025 | marketbeat.comUnited Therapeutics Corporation (NASDAQ:UTHR) Shares Bought by Achmea Investment Management B.V.June 27, 2025 | marketbeat.comRobeco Institutional Asset Management B.V. Buys 34,362 Shares of United Therapeutics Corporation (NASDAQ:UTHR)June 27, 2025 | marketbeat.comNew MarketBeat Followers Over TimeMedia Sentiment Over TimeTop HeadlinesView All HeadlinesAST SpaceMobile’s Star Is Rising: Get in While It’s Still Cheap!By Thomas Hughes | June 16, 2025View AST SpaceMobile’s Star Is Rising: Get in While It’s Still Cheap!Analysts Supercharge AMD Stock Ahead of Q2 AI CatalystBy Thomas Hughes | June 26, 2025View Analysts Supercharge AMD Stock Ahead of Q2 AI CatalystAs Oil Prices Rebound, These Stocks Could Fuel the Next RallyBy Sarah Horvath | June 9, 2025View As Oil Prices Rebound, These Stocks Could Fuel the Next Rally2 Under the Radar Space & Defense Stocks With Huge PotentialBy Leo Miller | July 1, 2025View 2 Under the Radar Space & Defense Stocks With Huge Potential3 Growth Stocks Too Small for Institutions to BuyBy Gabriel Osorio-Mazilli | June 19, 2025View 3 Growth Stocks Too Small for Institutions to BuyASND, ARWR, IONS, ACAD, and UTHR Company DescriptionsACADIA Pharmaceuticals NASDAQ:ACAD$20.95 -0.29 (-1.37%) Closing price 07/3/2025 03:39 PM EasternExtended Trading$20.95 0.00 (0.00%) As of 07/3/2025 04:20 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.ACADIA Pharmaceuticals Inc., a biopharmaceutical company, focuses on the development and commercialization innovative medicines that address unmet medical needs in central nervous system (CNS) disorders and rare diseases in the United States. The company offers NUPLAZID (pimavanserin) for the treatment of hallucinations and delusions associated with Parkinson's disease psychosis; and DAYBUE, a novel synthetic analog of the amino-terminal tripeptide of insulin-like growth factor 1 for treatment of Rett Syndrome. It also develops Pimavanserin that is in Phase III ADVANCE-2 study to treat the negative symptoms of schizophrenia; ACP-101 whixh is in Phase III for the treatment of hyperphagia in Prader-Willi syndrome; ACP-204 which is in Phase II for the treatment of Alzheimer's disease psychosis; ACP-2591 that is in Phase I for Rett syndrome and Fragile X syndrome; preclinical antisense oligonucleotide programs; and other programs for neuropsychiatric symptoms. It has a license agreement with Neuren Pharmaceuticals Limited to develop and commercialize trofinetide for Rett syndrome and other indications; and a license and collaboration agreement with Stoke Therapeutics, Inc. to discover, develop and commercialize novel RNA-based medicines for the potential treatment of severe and rare genetic neurodevelopmental diseases of the CNS. The company was formerly known as Receptor Technologies, Inc. and changed its name ACADIA Pharmaceuticals Inc. in 1997. ACADIA Pharmaceuticals Inc. was incorporated in 1993 and is headquartered in San Diego, California.Arrowhead Pharmaceuticals NASDAQ:ARWR$16.78 -0.12 (-0.71%) Closing price 07/3/2025 03:44 PM EasternExtended Trading$16.78 0.00 (0.00%) As of 07/3/2025 04:20 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Arrowhead Pharmaceuticals, Inc. develops medicines for the treatment of intractable diseases in the United States. The company's products in pipeline includes Plozasiran, which is in Phase 2b and one Phase 3 clinical trial to treat hypertriglyceridemia, mixed dyslipidemia, and chylomicronemia syndrome; Zodasiran that is in Phase 2b clinical trial for the treatment of dyslipidemia and hypertriglyceridemia; ARO-PNPLA3, which is in Phase 1 clinical trial to treat patients with non-alcoholic steatohepatitis; ARO-RAGE that is in Phase 1/2a clinical trial to treat inflammatory pulmonary conditions; and ARO-MUC5AC, which is in Phase 1/2a clinical trial to treat muco-obstructive pulmonary diseases. It also develops ARO-MMP7 that is in Phase 1/2a clinical trial for treatment of idiopathic pulmonary fibrosis; ARO-DUX4 for the treatment of facioscapulohumeral muscular dystrophy; ARO-SOD1 for the potential treatment of amyotrophic lateral sclerosis; and ARO-C3, which is in Phase 1/2a clinical trial for the treatment of patients with various complement mediated or complement associated renal diseases. In addition, the company is involved in the development of JNJ-3989, which is in Phase 2 clinical trial to treat chronic hepatitis B virus infection; Olpasiran that is in Phase 3 clinical trial to reduce the production of apolipoprotein A; GSK-4532990 that is in phase 2 clinical trial to treat liver diseases; HZN-457, which is in phase 1 clinical trial to treat uncontrolled gout; and Fazirsiran that is in Phase 3 clinical trial for the treatment for liver disease associated with alpha-1 antitrypsin deficiency. Arrowhead Pharmaceuticals, Inc. has license and research collaboration agreements with Janssen Pharmaceuticals, Inc.; Takeda Pharmaceutical Company Limited; Horizon Therapeutics Ireland DAC; Amgen Inc.; and Glaxosmithkline Intellectual Property (No. 3) Limited. The company was founded in 2003 and is headquartered in Pasadena, California.Ascendis Pharma A/S NASDAQ:ASND$174.07 +0.97 (+0.56%) Closing price 07/3/2025 02:42 PM EasternExtended Trading$174.07 0.00 (0.00%) As of 07/3/2025 04:01 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Ascendis Pharma A/S, a biopharmaceutical company, focuses on developing therapies for unmet medical needs. It offers SKYTROFA for treating patients with growth hormone deficiency (GHD). The company is also developing a pipeline of three independent endocrinology rare disease product candidates in clinical development, as well as focuses on advancing oncology therapeutic candidates. The company was incorporated in 2006 and is headquartered in Hellerup, Denmark.Ionis Pharmaceuticals NASDAQ:IONS$42.98 -0.61 (-1.40%) Closing price 07/3/2025 02:44 PM EasternExtended Trading$42.64 -0.34 (-0.79%) As of 07/3/2025 04:08 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Ionis Pharmaceuticals, Inc. discovers and develops RNA-targeted therapeutics in the United States. The company offers SPINRAZA for spinal muscular atrophy (SMA) in pediatric and adult patients; TEGSEDI, an antisense injection for the treatment of polyneuropathy caused by hereditary transthyretin amyloidosis in adults; and WAYLIVRA, an antisense medicine for treatment for familial chylomicronemia syndrome (FCS) and familial partial lipodystrophy. It also develops medicines for various indications that are in phase 3 study, including Eplontersen as a monthly self-administered subcutaneous injection to treat all types of ATTR; Olezarsen for patients with FCS and severe hypertriglyceridemia (SHTG); Donidalorsen for patients with hereditary angioedema; ION363 for patients with amyotrophic lateral sclerosis; Tofersen to inhibit the production of superoxide dismutase 1; Pelacarsen for patients with established cardiovascular disease and elevated lipoprotein(a); and Bepirovirsen to inhibit the production of viral proteins associated with hepatitis B virus. In addition, the company develops IONIS-FB-LRx to inhibit the production of complement factor B and the alternative complement pathway; and ION224 to reduce the production of diacylglycerol acyltransferase 2. It has a strategic collaboration with Biogen for the treatment of neurological disorders; and collaboration and license agreement with Metagenomi, Inc, AstraZeneca, Bayer AG, GlaxoSmithKline plc, Novartis, Roche, Swedish Orphan Biovitrum AB, and PTC Therapeutics. The company was incorporated in 1989 and is based in Carlsbad, California.United Therapeutics NASDAQ:UTHR$294.57 -0.65 (-0.22%) Closing price 07/3/2025 02:47 PM EasternExtended Trading$294.57 0.00 (0.00%) As of 07/3/2025 04:32 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.United Therapeutics Corporation, a biotechnology company, engages in the development and commercialization of products to address the unmet medical needs of patients with chronic and life-threatening diseases in the United States and internationally. The company offers Tyvaso DPI, an inhaled dry powder via pre-filled and single-use cartridges; Tyvaso, an inhaled solution via ultrasonic nebulizer; Remodulin (treprostinil) injection to treat patients with pulmonary arterial hypertension (PAH) to diminish symptoms associated with exercise; Orenitram, a tablet dosage form of treprostinil, to delay disease progression and improve exercise capacity in PAH patients; and Adcirca, an oral PDE-5 inhibitor to enhance the exercise ability in PAH patients. It also markets and sells Unituxin (dinutuximab) injection, a monoclonal antibody for treating high-risk neuroblastoma; and Remunity Pump, which contains a pump and separate controller for Remodulin. In addition, the company engages in developing RemoPro and Ralinepag for the treatment of PAH; Aurora-GT, a gene therapy product to rebuild the blood vessels in the lungs; and Nebulized Tyvaso, for the treatment of idiopathic pulmonary fibrosis, as well as xenografts, which are development-stage organ products. It has licensing and collaboration agreements with DEKA Research & Development Corp. to develop a semi-disposable system for the subcutaneous delivery of treprostinil; MannKind Corporation to develop and license treprostinil inhalation powder and the Dreamboat device; and Arena Pharmaceuticals, Inc. to develop Ralinepag. The company was incorporated in 1996 and is headquartered in Silver Spring, Maryland. 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