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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:ARWR NYSEARCA:LABD NYSEARCA:LABU NASDAQ:MDGL On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeARWRArrowhead Pharmaceuticals$16.76-11.1%$16.34$9.57▼$29.86$2.60B0.931.58 million shs3.01 million shsLABDDirexion Daily S&P Biotech Bear 3x Shares$6.52+6.2%$7.59$4.78▼$16.05$79.97M-2.416.43 million shs25.54 million shsLABUDirexion Daily S&P Biotech Bull 3x Shares$62.76-6.5%$57.24$32.55▼$152.60$654.21M31.46 million shs3.17 million shsMDGLMadrigal Pharmaceuticals$334.13-4.2%$291.89$200.63▼$377.46$7.74B-1.05361,550 shs326,009 shsReduce the RiskMarket downturns give many investors pause, and for good reason. Wondering how to offset this risk? Enter your email address to learn more about using beta to protect your portfolio.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceARWRArrowhead Pharmaceuticals-11.09%-8.47%+7.30%+49.11%-40.19%LABDDirexion Daily S&P Biotech Bear 3x Shares+6.19%+2.03%-13.87%-36.82%+11.45%LABUDirexion Daily S&P Biotech Bull 3x Shares-6.52%-3.51%+10.63%+33.53%-54.95%MDGLMadrigal Pharmaceuticals-4.19%+5.92%+18.18%+10.76%+24.03%Compare MarketRank™CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & ValuationARWRArrowhead Pharmaceuticals3.8394 of 5 stars3.42.00.03.43.61.70.0LABDDirexion Daily S&P Biotech Bear 3x SharesN/AN/AN/AN/AN/AN/AN/AN/ALABUDirexion Daily S&P Biotech Bull 3x SharesN/AN/AN/AN/AN/AN/AN/AN/AMDGLMadrigal Pharmaceuticals4.3465 of 5 stars3.41.00.04.62.54.20.6Compare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceARWRArrowhead Pharmaceuticals 2.75Moderate Buy$43.71160.83% UpsideLABDDirexion Daily S&P Biotech Bear 3x Shares 0.00N/AN/AN/ALABUDirexion Daily S&P Biotech Bull 3x Shares 2.75Moderate Buy$62.76N/AMDGLMadrigal Pharmaceuticals 2.89Moderate Buy$420.6325.89% UpsideCurrent Analyst Ratings BreakdownLatest LABU, MDGL, ARWR, and LABD Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails5/20/2025ARWRArrowhead PharmaceuticalsHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$80.00 ➝ $80.005/13/2025ARWRArrowhead PharmaceuticalsCitigroupSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetNeutral ➝ Neutral$21.00 ➝ $17.005/13/2025ARWRArrowhead PharmaceuticalsChardan CapitalSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$60.00 ➝ $60.005/2/2025MDGLMadrigal PharmaceuticalsUBS GroupSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetBuy ➝ Buy$441.00 ➝ $458.005/2/2025MDGLMadrigal PharmaceuticalsB. RileySubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$422.00 ➝ $460.005/2/2025MDGLMadrigal PharmaceuticalsCanaccord Genuity GroupSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetBuy ➝ Buy$394.00 ➝ $420.004/24/2025MDGLMadrigal PharmaceuticalsJMP SecuritiesSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingMarket Outperform ➝ Market Outperform$443.00 ➝ $443.00(Data available from 7/19/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookARWRArrowhead Pharmaceuticals$3.55M651.99N/AN/A$1.54 per share10.88LABDDirexion Daily S&P Biotech Bear 3x SharesN/AN/AN/AN/AN/AN/ALABUDirexion Daily S&P Biotech Bull 3x SharesN/AN/AN/AN/AN/AN/AMDGLMadrigal Pharmaceuticals$317.38M23.37N/AN/A$34.59 per share9.66Compare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateARWRArrowhead Pharmaceuticals-$599.49M-$1.40N/AN/A22.17N/A-45.33%-12.49%8/6/2025 (Estimated)LABDDirexion Daily S&P Biotech Bear 3x SharesN/AN/A0.00∞N/AN/AN/AN/AN/ALABUDirexion Daily S&P Biotech Bull 3x SharesN/AN/A0.00∞N/AN/AN/AN/AN/AMDGLMadrigal Pharmaceuticals-$465.89M-$18.05N/AN/AN/A-123.38%-50.54%-37.19%8/6/2025 (Estimated)Latest LABU, MDGL, ARWR, and LABD EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails8/14/2025Q3 2025ARWRArrowhead Pharmaceuticals-$0.94N/AN/AN/AN/AN/A8/6/2025Q2 2025MDGLMadrigal Pharmaceuticals-$3.64N/AN/AN/A$158.94 millionN/A5/12/2025Q2 2025ARWRArrowhead Pharmaceuticals-$0.06$2.75+$2.81$2.75$116.27 million$542.71 million5/1/2025Q1 2025MDGLMadrigal Pharmaceuticals-$3.62-$3.32+$0.30-$3.32$112.79 million$137.25 millionCompare DividendsCompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive GrowthARWRArrowhead PharmaceuticalsN/AN/AN/AN/AN/ALABDDirexion Daily S&P Biotech Bear 3x Shares$0.274.14%N/AN/AN/ALABUDirexion Daily S&P Biotech Bull 3x Shares$0.320.51%N/AN/AN/AMDGLMadrigal PharmaceuticalsN/AN/AN/AN/AN/ACompare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioARWRArrowhead Pharmaceuticals0.315.155.15LABDDirexion Daily S&P Biotech Bear 3x SharesN/AN/AN/ALABUDirexion Daily S&P Biotech Bull 3x SharesN/AN/AN/AMDGLMadrigal Pharmaceuticals0.175.915.58Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipARWRArrowhead Pharmaceuticals62.61%LABDDirexion Daily S&P Biotech Bear 3x SharesN/ALABUDirexion Daily S&P Biotech Bull 3x SharesN/AMDGLMadrigal Pharmaceuticals98.50%Insider OwnershipCompanyInsider OwnershipARWRArrowhead Pharmaceuticals4.30%LABDDirexion Daily S&P Biotech Bear 3x SharesN/ALABUDirexion Daily S&P Biotech Bull 3x SharesN/AMDGLMadrigal Pharmaceuticals21.50%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableARWRArrowhead Pharmaceuticals400138.10 million132.16 millionOptionableLABDDirexion Daily S&P Biotech Bear 3x SharesN/A12.27 millionN/ANot OptionableLABUDirexion Daily S&P Biotech Bull 3x SharesN/A10.42 millionN/ANot OptionableMDGLMadrigal Pharmaceuticals9022.20 million17.43 millionOptionableLABU, MDGL, ARWR, and LABD HeadlinesRecent News About These CompaniesMadrigal Pharmaceuticals Receives Notice of Allowance from U.S. Patent and Trademark Office for New U.S. Patent Covering Rezdiffra™ (Resmetirom)July 18 at 3:35 PM | taiwannews.com.twTMadrigal Pharmaceuticals Hits 80-Plus Relative Strength Rating BenchmarkJuly 18 at 3:35 PM | msn.comNew York State Common Retirement Fund Boosts Holdings in Madrigal Pharmaceuticals, Inc. (NASDAQ:MDGL)July 18 at 4:17 AM | marketbeat.comMDGL Stock Soars 11% on New Patent Protecting Rezdiffra Dosing RightsJuly 17 at 12:35 PM | zacks.comMadrigal (MDGL) Moves 10.9% Higher: Will This Strength Last?July 17 at 8:11 AM | zacks.comMadrigal stock jumps as patent protection for MASH treatment extendedJuly 16 at 8:21 PM | in.investing.comMadrigal Pharmaceuticals shares surge after extended patent protection for MASH therapyJuly 16 at 8:21 PM | msn.comMadrigal Pharmaceuticals (NASDAQ:MDGL) Shares Gap Up - Should You Buy?July 16 at 10:59 AM | marketbeat.comMadrigal Pharmaceuticals Receives Notice of Allowance from U.S. Patent and Trademark Office for New U.S. Patent Covering Rezdiffraâ„¢ (Resmetirom)July 16 at 8:13 AM | globenewswire.comEmerald Advisers LLC Has $15.87 Million Stake in Madrigal Pharmaceuticals, Inc. (NASDAQ:MDGL)July 13, 2025 | marketbeat.comEmerald Mutual Fund Advisers Trust Purchases 16,582 Shares of Madrigal Pharmaceuticals, Inc. (NASDAQ:MDGL)July 12, 2025 | marketbeat.comD.A. Davidson & CO. Acquires 1,458 Shares of Madrigal Pharmaceuticals, Inc. (NASDAQ:MDGL)July 10, 2025 | marketbeat.comCannon Global Investment Management LLC Makes New $497,000 Investment in Madrigal Pharmaceuticals, Inc. (NASDAQ:MDGL)July 3, 2025 | marketbeat.comMadrigal Pharma (MDGL) Share News Today - Investing.com UKJuly 2, 2025 | uk.investing.comJMP Reaffirms Price Target for Madrigal Amid Rezdiffra Growth PotentialJuly 2, 2025 | msn.comMadrigal Pharmaceuticals, Inc. (NASDAQ:MDGL) Receives Consensus Rating of "Moderate Buy" from AnalystsJuly 1, 2025 | marketbeat.comMadrigal, Viking among notable gainers after Altimmune’s MASH setbackJune 26, 2025 | msn.comMadrigal Pharmaceuticals Closer to EU Approval for First MASH Treatment, RezdiffraJune 24, 2025 | msn.comMadrigal Pharmaceuticals: GLP-1s Inch Closer To MASH Market As REZDIFFRA OutperformsJune 23, 2025 | seekingalpha.comMadrigal Pharmaceuticals (NASDAQ:MDGL) Stock, Insider Trading ActivityJune 21, 2025 | benzinga.comEU regulator backs conditional authorisation for Madrigal's liver disease drugJune 20, 2025 | msn.comNew MarketBeat Followers Over TimeMedia Sentiment Over TimeLABU, MDGL, ARWR, and LABD Company DescriptionsArrowhead Pharmaceuticals NASDAQ:ARWR$16.76 -2.09 (-11.09%) Closing price 07/18/2025 04:00 PM EasternExtended Trading$16.86 +0.10 (+0.60%) As of 07/18/2025 07:54 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Arrowhead Pharmaceuticals, Inc. develops medicines for the treatment of intractable diseases in the United States. The company's products in pipeline includes Plozasiran, which is in Phase 2b and one Phase 3 clinical trial to treat hypertriglyceridemia, mixed dyslipidemia, and chylomicronemia syndrome; Zodasiran that is in Phase 2b clinical trial for the treatment of dyslipidemia and hypertriglyceridemia; ARO-PNPLA3, which is in Phase 1 clinical trial to treat patients with non-alcoholic steatohepatitis; ARO-RAGE that is in Phase 1/2a clinical trial to treat inflammatory pulmonary conditions; and ARO-MUC5AC, which is in Phase 1/2a clinical trial to treat muco-obstructive pulmonary diseases. It also develops ARO-MMP7 that is in Phase 1/2a clinical trial for treatment of idiopathic pulmonary fibrosis; ARO-DUX4 for the treatment of facioscapulohumeral muscular dystrophy; ARO-SOD1 for the potential treatment of amyotrophic lateral sclerosis; and ARO-C3, which is in Phase 1/2a clinical trial for the treatment of patients with various complement mediated or complement associated renal diseases. In addition, the company is involved in the development of JNJ-3989, which is in Phase 2 clinical trial to treat chronic hepatitis B virus infection; Olpasiran that is in Phase 3 clinical trial to reduce the production of apolipoprotein A; GSK-4532990 that is in phase 2 clinical trial to treat liver diseases; HZN-457, which is in phase 1 clinical trial to treat uncontrolled gout; and Fazirsiran that is in Phase 3 clinical trial for the treatment for liver disease associated with alpha-1 antitrypsin deficiency. Arrowhead Pharmaceuticals, Inc. has license and research collaboration agreements with Janssen Pharmaceuticals, Inc.; Takeda Pharmaceutical Company Limited; Horizon Therapeutics Ireland DAC; Amgen Inc.; and Glaxosmithkline Intellectual Property (No. 3) Limited. The company was founded in 2003 and is headquartered in Pasadena, California.Direxion Daily S&P Biotech Bear 3x Shares NYSEARCA:LABD$6.52 +0.38 (+6.19%) Closing price 07/18/2025 04:10 PM EasternExtended Trading$6.50 -0.02 (-0.31%) As of 07/18/2025 07:59 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.The Direxion Daily S&P Biotech Bear 3X Shares (LABD) is an exchange-traded fund that is based on the S&P Biotechnology Select Industry index. The fund provides daily 3 times inverse exposure to the S&P Biotechnology Select Industry Index. LABD was launched on May 28, 2015 and is managed by Direxion.Direxion Daily S&P Biotech Bull 3x Shares NYSEARCA:LABU$62.76 -4.38 (-6.52%) Closing price 07/18/2025 04:10 PM EasternExtended Trading$63.13 +0.37 (+0.59%) As of 07/18/2025 08:00 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.The Direxion Daily S&P Biotech Bull 3X Shares (LABU) is an exchange-traded fund that is based on the S&P Biotechnology Select Industry index. The fund provides daily 3 times exposure to the S&P Biotechnology Select Industry Index. LABU was launched on May 28, 2015 and is managed by Direxion.Madrigal Pharmaceuticals NASDAQ:MDGL$334.13 -14.60 (-4.19%) Closing price 07/18/2025 04:00 PM EasternExtended Trading$332.00 -2.13 (-0.64%) As of 07/18/2025 05:38 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Madrigal Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on the development of therapeutics for the treatment of non-alcoholic steatohepatitis (NASH) in the United States. Its lead product candidate is resmetirom, a liver-directed thyroid hormone receptor beta agonist, which is in Phase 3 clinical trials for treating NASH. The company is headquartered in West Conshohocken, Pennsylvania. 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