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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NYSE:AMPEOTCMKTS:ATRXNASDAQ:CALAOTCMKTS:SPHS On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeAMPEAmpio Pharmaceuticals$0.00-3.2%$0.00$0.00▼$0.45$3K3.9435 shs105 shsATRXAdhera Therapeutics$0.00$0.00▼$0.02$1K4.0311,064 shsN/ACALACalithera Biosciences$0.00$0.00$0.00▼$0.12$3K-2.3818,694 shsN/ASPHSSophiris Bio$0.00$0.00▼$0.05$4K1.94N/AN/A13 Stocks Institutional Investors Won't Stop BuyingWhich stocks are hedge funds and endowments buying in today's market? Enter your email address and we'll send you MarketBeat's list of thirteen stocks that institutional investors are buying now.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceAMPEAmpio Pharmaceuticals0.00%0.00%+42.86%+42.86%-98.76%ATRXAdhera Therapeutics0.00%0.00%0.00%0.00%-97.78%CALACalithera Biosciences0.00%0.00%-88.00%0.00%-97.00%SPHSSophiris Bio0.00%0.00%0.00%0.00%0.00%Compare MarketRank™CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & ValuationAMPEAmpio PharmaceuticalsN/AN/AN/AN/AN/AN/AN/AN/AATRXAdhera TherapeuticsN/AN/AN/AN/AN/AN/AN/AN/ACALACalithera BiosciencesN/AN/AN/AN/AN/AN/AN/AN/ASPHSSophiris BioN/AN/AN/AN/AN/AN/AN/AN/ACompare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceAMPEAmpio Pharmaceuticals 0.00N/AN/AN/AATRXAdhera Therapeutics 0.00N/AN/AN/ACALACalithera Biosciences 0.00N/AN/AN/ASPHSSophiris Bio 0.00N/AN/AN/ACompare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookAMPEAmpio PharmaceuticalsN/AN/AN/AN/A$4.04 per shareN/AATRXAdhera TherapeuticsN/AN/AN/AN/AN/AN/ACALACalithera BiosciencesN/AN/AN/AN/AN/AN/ASPHSSophiris BioN/AN/AN/AN/AN/AN/ACompare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateAMPEAmpio Pharmaceuticals-$8.63M-$11.01N/A∞N/AN/AN/AN/AN/AATRXAdhera Therapeutics-$2.11MN/A0.00N/AN/AN/AN/AN/AN/ACALACalithera Biosciences-$39.65MN/A0.00∞N/AN/AN/AN/AN/ASPHSSophiris BioN/AN/A0.00N/AN/AN/AN/AN/AN/ACompare DividendsCompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive GrowthAMPEAmpio PharmaceuticalsN/AN/AN/AN/AN/AATRXAdhera TherapeuticsN/AN/AN/AN/AN/ACALACalithera BiosciencesN/AN/AN/AN/AN/ASPHSSophiris BioN/AN/AN/AN/AN/ACompare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipAMPEAmpio Pharmaceuticals5.73%ATRXAdhera TherapeuticsN/ACALACalithera BiosciencesN/ASPHSSophiris BioN/AInsider OwnershipCompanyInsider OwnershipAMPEAmpio Pharmaceuticals3.30%ATRXAdhera Therapeutics28.20%CALACalithera Biosciences6.60%SPHSSophiris Bio4.50%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableAMPEAmpio Pharmaceuticals201.14 million1.10 millionNo DataATRXAdhera Therapeutics211.63 million8.35 millionNot OptionableCALACalithera Biosciences604.87 million4.55 millionNot OptionableSPHSSophiris Bio635.55 millionN/ANot OptionableATRX, SPHS, AMPE, and CALA HeadlinesRecent News About These CompaniesWisr AI Systems Inc. Announces Closing of AmalgamationDecember 20, 2024 | newsfilecorp.comBioinspired materials articles from across Nature PortfolioNovember 13, 2024 | nature.comRyan Garcia: Biography, record, fights and moreDecember 3, 2023 | espn.comBest Louisiana High SchoolsOctober 13, 2023 | usnews.comSouth Portland High sends students home after morning lockdownOctober 9, 2023 | pressherald.comBLTE - Belite Bio, IncJuly 20, 2023 | finance.yahoo.comTycho Brahe: Colorful life, accomplishments and bizarre deathJune 23, 2023 | space.comBio-Reference LaboratoriesJune 12, 2023 | forbes.comCommunity News – Calling all Red Riots; South Portland H.S. Alumni Network launchedApril 15, 2023 | pressherald.comUkraine conflict: Germany orders 10 PzH 2000 SPHs to replace those sent to KyivApril 2, 2023 | janes.comSophiris Bio Inc. Registered Sh (BFF1.SG)March 20, 2023 | finance.yahoo.com18 ways you didn't know you could use bio-oil, plus the celebs who swear by itMarch 18, 2023 | womenshealthmag.comSPHS Indoor Track Wins Girls Blue Division at GMC ChampionshipsJanuary 25, 2023 | msn.comSPHS Weekly Sports Recap: All Sports Notch Big WinsJanuary 17, 2023 | msn.comPennsylvania Gov.-elect Josh Shapiro biographyJanuary 14, 2023 | wgal.comNarendra Modi Biography: Childhood, Family, Education, Political Life, Net Worth & Key FactsSeptember 17, 2022 | jagranjosh.comWeapons newsSeptember 9, 2022 | janes.comNew MarketBeat Followers Over TimeTop HeadlinesView All HeadlinesArcher Aviation Gets Analyst Target Upgrade: Time to Load Up?By Jeffrey Neal Johnson | April 25, 2025View Archer Aviation Gets Analyst Target Upgrade: Time to Load Up?Qualcomm Is 5x Cheaper Than AMD, But Won’t Be for LongBy Sam Quirke | May 13, 2025View Qualcomm Is 5x Cheaper Than AMD, But Won’t Be for LongWhy D-Wave's Project With Davidson Is a Game-Changer For QuantumBy Nathan Reiff | April 30, 2025View Why D-Wave's Project With Davidson Is a Game-Changer For QuantumNVIDIA Stock Surges on Bullish News: How High Could It Climb?By Thomas Hughes | May 13, 2025View NVIDIA Stock Surges on Bullish News: How High Could It Climb?Churchill Downs Stock: Could Tariff Fears Dampen Derby Gains?By Chris Markoch | April 26, 2025View Churchill Downs Stock: Could Tariff Fears Dampen Derby Gains?ATRX, SPHS, AMPE, and CALA Company DescriptionsAmpio Pharmaceuticals NYSE:AMPE$0.0030 0.00 (-3.23%) As of 05/22/2025 12:37 PM EasternAmpio Pharmaceuticals, Inc., a biopharmaceutical company, develops therapies for the treatment of osteoarthritis of the knee (OAK) in the United States. It develops OA-201, a small molecule formulation for the treatment of OAK pain. The company is headquartered in Englewood, Colorado.Adhera Therapeutics OTCMKTS:ATRXAdhera Therapeutics, Inc., a biotech company, focuses on the discovery, development, and commercialization of small molecule drugs. The company is developing MLR-1019 for the treatment of Parkinson's disease; and MLR -1023 to treat Type 1 diabetes. The company was formerly known as Marina Biotech, Inc. and changed its name to Adhera Therapeutics, Inc. in October 2018. Adhera Therapeutics, Inc. is based in Baton Rouge, Louisiana.Calithera Biosciences NASDAQ:CALA$0.0006 0.00 (0.00%) As of 05/22/2025Calithera Biosciences, Inc. operates under a plan of liquidation that was approved in January 2023. Previously, the company was engaged in the clinical stage precision oncology biopharmaceutical business. Calithera Biosciences, Inc. was incorporated in 2010 and is headquartered in South San Francisco, California.Sophiris Bio OTCMKTS:SPHSSophiris Bio, Inc. is a clinical-stage biopharmaceutical company, which engages in the development of products for the treatment of urological diseases. The company was founded by James L. Heppell in May 2003 and is headquartered in La Jolla, CA. 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