NASDAQ:ALNY Alnylam Pharmaceuticals (ALNY) Stock Price, News & Analysis $159.89 +1.89 (+1.20%) Closing price 11/3/2026 04:00 PM EasternExtended Trading$158.79 -1.10 (-0.68%) As of 11/3/2026 07:46 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsInsider TradesNews and TrendsOptions ChainOwnershipSEC FilingsShort Interest About Alnylam Pharmaceuticals Stock (NASDAQ:ALNY) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get ALNY alerts:Sign Up Key Stats Today's Range$156.72▼$161.5850-Day Range$158.00▼$267.4052-Week Range$156.00▼$479.79Volume3.76 million shsAverage Volume2.34 million shsMarket Capitalization$21.42 billionP/E Ratio8.30Dividend YieldN/APrice Target$305.86Consensus RatingModerate Buy Company Overview Alnylam Pharmaceuticals, Inc. is a biopharmaceutical company focused on developing and commercializing medicines based on RNA interference (RNAi). The company’s therapies are designed to silence specific genes involved in disease, with the goal of addressing the underlying causes of genetic and other serious conditions. Alnylam’s marketed products include ONPATTRO (patisiran) and AMVUTTRA (vutrisiran) for hereditary transthyretin-mediated amyloidosis, GIVLAARI (givosiran) for acute hepatic porphyria, and OXLUMO (lumasiran) for primary hyperoxaluria type 1. The company also maintains a pipeline of investigational RNAi medicines targeting diseases in areas such as genetic disorders, cardiometabolic conditions, and central nervous system diseases. Founded in 2002 and headquartered in Cambridge, Massachusetts, Alnylam serves patients internationally through its commercial operations and collaborations with other pharmaceutical companies. The company’s leadership includes President and Chief Executive Officer Yvonne Greenstreet, who has led Alnylam since 2022.AI Generated. May Contain Errors. Read More Alnylam Pharmaceuticals Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks94th Percentile Overall ScoreALNY MarketRank™: 4.723210755235 of 5 starsAlnylam Pharmaceuticals scored higher than 94% of companies evaluated by MarketBeat, and ranked 47th out of 901 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion4.3 / 5Analyst RatingModerate Buy Consensus RatingAlnylam Pharmaceuticals has received a consensus rating of Moderate Buy. The company's average rating score is 2.65, and is based on 1 strong buy rating, 15 buy ratings, 10 hold ratings, and no sell ratings.Upside PotentialAlnylam Pharmaceuticals has a consensus price target of $305.86, representing about 91.3% upside from its current price of $159.89.Amount of Analyst CoverageAlnylam Pharmaceuticals has been the subject of 24 research reports in the past 90 days, demonstrating strong analyst interest in this stock.Read more about Alnylam Pharmaceuticals' stock forecast and price target. Earnings and Valuation3.1 / 5Proj. Earnings Growth37.08% Earnings GrowthEarnings for Alnylam Pharmaceuticals are expected to grow by 37.08% in the coming year, from $6.58 to $9.02 per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Alnylam Pharmaceuticals is 8.30, which means that it is trading at a less expensive P/E ratio than the market average P/E ratio of about 25.48.Price to Earnings Ratio vs. SectorThe P/E ratio of Alnylam Pharmaceuticals is 8.30, which means that it is trading at a less expensive P/E ratio than the Healthcare sector average P/E ratio of about 35.73.Price to Book Value per Share RatioAlnylam Pharmaceuticals has a P/B Ratio of 5.94. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities. Short Interest4.0 / 5Short Interest LevelHealthy Percentage of Shares Shorted4.95% of the float of Alnylam Pharmaceuticals has been sold short.Short Interest Ratio / Days to CoverAlnylam Pharmaceuticals has a short interest ratio ("days to cover") of 5.1.Change versus previous monthShort interest in Alnylam Pharmaceuticals has recently decreased by 14.82%, indicating that investor sentiment is improving significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldAlnylam Pharmaceuticals does not currently pay a dividend.Dividend GrowthAlnylam Pharmaceuticals does not have a long track record of dividend growth. News and Social Media2.4 / 5News Sentiment-0.12 News SentimentAlnylam Pharmaceuticals has a news sentiment score of -0.12. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.50 average news sentiment score of Healthcare companies.News Coverage This WeekMarketBeat has tracked 74 news articles for Alnylam Pharmaceuticals this week, compared to 11 articles on an average week.Search Interest19 people have searched for ALNY on MarketBeat in the last 30 days. This is an increase of 27% compared to the previous 30 days.MarketBeat Follows6 people have added Alnylam Pharmaceuticals to their MarketBeat watchlist in the last 30 days. This is an increase of 50% compared to the previous 30 days. Company Ownership1.5 / 5Insider TradingSelling Shares Insider Buying vs. Insider SellingIn the past three months, Alnylam Pharmaceuticals insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $398,855.00 in company stock.Percentage Held by Insiders0.86% of the stock of Alnylam Pharmaceuticals is held by insiders.Percentage Held by Institutions92.97% of the stock of Alnylam Pharmaceuticals is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about Alnylam Pharmaceuticals' insider trading history. Receive ALNY Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Alnylam Pharmaceuticals and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsSMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. 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ALNY Stock News HeadlinesCanaccord Genuity Group Issues Pessimistic Forecast for Alnylam Pharmaceuticals (NASDAQ:ALNY) Stock Price2 hours ago | americanbankingnews.comBarclays Has Lowered Expectations for Alnylam Pharmaceuticals (NASDAQ:ALNY) Stock Price2 hours ago | americanbankingnews.comI'm handing you this one freeElon Musk doesn't own the chip powering every Tesla, every Starlink dish, and every AI satellite he builds, he licenses it from one overlooked company. That supplier just got a major catalyst. Musk filed to launch 1,000,000 satellites, a move analyst Dylan believes could drive a 100X bigger bill for this chipmaker starting December 8th. | Behind the Markets (Ad)What Could Alnylam Pharmaceuticals (ALNY) Five Year HELIOS B Data Change?November 3 at 10:47 PM | finance.yahoo.comRaymond James downgrades Alnylam Pharmaceuticals, Inc. - Depositary Receipt to outperform from strong buyNovember 3 at 5:47 PM | msn.comAlnylam to Present Five-Year HELIOS-B Data and Expanding Evidence on the Benefits of RNAi-Powered TTR Silencing with AMVUTTRA® (vutrisiran) at AHA and ISA 2026November 3 at 9:00 AM | businesswire.comBernstein downgrades Alnylam Pharmaceuticals, Inc. - Depositary Receipt to market perform from outperformNovember 3 at 2:23 AM | msn.comAlnylam Pharmaceuticals (NASDAQ:ALNY) EVP Bryan Supran Sells 1,758 Shares of StockOctober 7, 2026 | insidertrades.comSee More Headlines ALNY Stock Analysis - Frequently Asked Questions How have ALNY shares performed this year? Alnylam Pharmaceuticals' stock was trading at $397.65 on January 1st, 2026. Since then, ALNY shares have decreased by 59.8% and is now trading at $159.89. How were Alnylam Pharmaceuticals' earnings last quarter? Alnylam Pharmaceuticals, Inc. (NASDAQ:ALNY) announced its quarterly earnings results on Thursday, October, 29th. The biopharmaceutical company reported $16.26 EPS for the quarter, beating the consensus estimate of $1.66 by $14.60. The company's revenue for the quarter was up 16.7% compared to the same quarter last year. Read the conference call transcript. Who are Alnylam Pharmaceuticals' major shareholders? Alnylam Pharmaceuticals' top institutional investors include Pictet Asset Management Holding SA (0.37%), Sumitomo Mitsui Trust Group Inc. (0.24%), Assenagon Asset Management S.A. (0.13%) and ProShare Advisors LLC (0.10%). Insiders that own company stock include Yvonne Greenstreet, Jeffrey V Poulton, Tolga Tanguler, Pushkal Garg, Kevin Joseph Fitzgerald, Michael W Bonney, Bryan Supran, Melissa Mclaughlin, Amy W Schulman, David E I Pyott, Dennis A Ausiello, Colleen F Reitan and Phillip A Sharp. View institutional ownership trends. How do I buy shares of Alnylam Pharmaceuticals? Shares of ALNY stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Alnylam Pharmaceuticals own? Based on aggregate information from My MarketBeat watchlists, some other companies that Alnylam Pharmaceuticals investors own include NVIDIA (NVDA), Tesla (TSLA), Gilead Sciences (GILD), Alibaba Group (BABA), Netflix (NFLX), Micron Technology (MU) and Bristol Myers Squibb (BMY). Company Calendar Last Earnings10/29/2026Today11/03/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Red Zone (9m+) 1-Year History Nov 25 Feb 26 May 26 Aug 26 Nov 26 ALNY's financial health is in the Red zone, according to TradeSmith. ALNY has been in this zone for over 9 months. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorHealthcare Industry Biotechnology Sub-IndustryBiotechnology Current SymbolNASDAQ:ALNY CIK1178670 Webwww.alnylam.com Phone(617) 551-8200Fax617-551-8101Employees2,770Year Founded2002Price Target and Rating Average Price Target for Alnylam Pharmaceuticals$305.86 High Price Target$455.00 Low Price Target$199.00 Potential Upside/Downside+91.3%Consensus RatingModerate Buy Rating Score (0-4)2.65 Research Coverage26 Analysts Profitability EPS (Trailing Twelve Months)$19.26 Trailing P/E Ratio8.30 Forward P/E Ratio17.73 P/E GrowthN/ANet Income$313.75 million Net Margins52.85% Pretax Margin15.59% Return on Equity155.33% Return on Assets44.81% Debt Debt-to-Equity Ratio0.18 Current Ratio2.48 Quick Ratio2.43 Sales & Book Value Annual Sales$3.71 billion Price / Sales5.77 Cash Flow$2.83 per share Price / Cash Flow56.51 Book Value$26.91 per share Price / Book5.94Miscellaneous Outstanding Shares133,940,000Free Float132,786,000Market Cap$21.42 billion OptionableOptionable Beta0.42 Social Links 7 Blue-Chip Stocks to Add To Your Forever PortfolioA strong long-term portfolio starts with companies that can survive recessions, inflation, changing consumer habits, and shifting market leadership. This report names seven blue-chip stocks across technology, retail, consumer staples, healthcare, networking, sporting goods, and utilities that offer investors a mix of stability, income, growth, and staying power.Get This Free Report This page (NASDAQ:ALNY) was last updated on 11/3/2026 by MarketBeat.com Staff. From Our PartnersFinancial Legend: “Big trouble ahead …”Dr. Martin D. 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