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NASDAQ:MDGL

Madrigal Pharmaceuticals (MDGL) Stock Price, News & Analysis

Madrigal Pharmaceuticals logo
$529.09 +5.83 (+1.11%)
Closing price 09/16/2026 04:00 PM Eastern
Extended Trading
$532.53 +3.44 (+0.65%)
As of 08:21 AM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

About Madrigal Pharmaceuticals Stock (NASDAQ:MDGL)

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Key Stats

Today's Range
$517.45
$529.93
50-Day Range
$467.32
$560.01
52-Week Range
$393.61
$615.00
Volume
298,471 shs
Average Volume
198,504 shs
Market Capitalization
$12.22 billion
P/E Ratio
N/A
Dividend Yield
N/A
Price Target
$699.64
Consensus Rating
Moderate Buy

Company Overview

Madrigal Pharmaceuticals, Inc. (NASDAQ: MDGL) is a biopharmaceutical company focused on developing and commercializing therapies for cardiometabolic diseases, particularly nonalcoholic steatohepatitis, now commonly referred to as metabolic dysfunction-associated steatohepatitis (MASH).

The company’s lead product is Rezdiffra (resmetirom), an oral, thyroid hormone receptor beta agonist designed to target underlying liver disease. In 2024, the U.S. Food and Drug Administration approved Rezdiffra for use with diet and exercise to treat adults with noncirrhotic MASH and moderate to advanced liver fibrosis. The therapy is intended for patients whose condition has not progressed to cirrhosis.

Madrigal is headquartered in West Conshohocken, Pennsylvania, and its commercial activities initially center on the United States market. The company continues to pursue additional regulatory and commercial opportunities for resmetirom in international markets. William Sibold serves as chief executive officer, while Paul A. Friedman serves as executive chairman.

AI Generated. May Contain Errors.

Madrigal Pharmaceuticals Stock Analysis - MarketRank™

See Top-Rated MarketRank™ Stocks
65th Percentile Overall Score

MDGL MarketRank™: 

Madrigal Pharmaceuticals scored higher than 65% of companies evaluated by MarketBeat, and ranked 294th out of 903 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

  • Consensus Rating

    Madrigal Pharmaceuticals has received a consensus rating of Moderate Buy. The company's average rating score is 2.78, and is based on no strong buy ratings, 15 buy ratings, 2 hold ratings, and 1 sell rating.

  • Upside Potential

    Madrigal Pharmaceuticals has a consensus price target of $699.64, representing about 32.2% upside from its current price of $529.09.

  • Amount of Analyst Coverage

    Madrigal Pharmaceuticals has been the subject of 9 research reports in the past 90 days, demonstrating strong analyst interest in this stock.

  • Read more about Madrigal Pharmaceuticals' stock forecast and price target.
  • Earnings Growth

    Earnings for Madrigal Pharmaceuticals are expected to grow in the coming year, from ($7.03) to $5.55 per share.

  • Price to Earnings Ratio vs. the Market

    The P/E ratio of Madrigal Pharmaceuticals is -41.05, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

  • Price to Earnings Ratio vs. Sector

    The P/E ratio of Madrigal Pharmaceuticals is -41.05, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

  • Price to Book Value per Share Ratio

    Madrigal Pharmaceuticals has a P/B Ratio of 19.94. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.

  • Read more about Madrigal Pharmaceuticals' valuation and earnings.
  • Percentage of Shares Shorted

    11.77% of the float of Madrigal Pharmaceuticals has been sold short.
  • Short Interest Ratio / Days to Cover

    Madrigal Pharmaceuticals has a short interest ratio ("days to cover") of 9.46.
  • Change versus previous month

    Short interest in Madrigal Pharmaceuticals has recently increased by 10.62%, indicating that investor sentiment is decreasing significantly.
  • Dividend Yield

    Madrigal Pharmaceuticals does not currently pay a dividend.

  • Dividend Growth

    Madrigal Pharmaceuticals does not have a long track record of dividend growth.

  • News Sentiment

    Madrigal Pharmaceuticals has a news sentiment score of 0.70. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This news sentiment score is similar to the average news sentiment of Healthcare companies.
  • News Coverage This Week

    MarketBeat has tracked 8 news articles for Madrigal Pharmaceuticals this week, compared to 6 articles on an average week.
  • Search Interest

    Only 1 people have searched for MDGL on MarketBeat in the last 30 days. This is a decrease of -75% compared to the previous 30 days.
  • MarketBeat Follows

    4 people have added Madrigal Pharmaceuticals to their MarketBeat watchlist in the last 30 days. This is an increase of 100% compared to the previous 30 days.
  • Insider Buying vs. Insider Selling

    In the past three months, Madrigal Pharmaceuticals insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $6,581,182.00 in company stock.

  • Percentage Held by Insiders

    17.60% of the stock of Madrigal Pharmaceuticals is held by insiders. A high percentage of insider ownership can be a sign of company health.

  • Percentage Held by Institutions

    98.50% of the stock of Madrigal Pharmaceuticals is held by institutions. High institutional ownership can be a signal of strong market trust in this company.

  • Read more about Madrigal Pharmaceuticals' insider trading history.
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MDGL Stock News Headlines

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MDGL Stock Analysis - Frequently Asked Questions

Madrigal Pharmaceuticals' stock was trading at $582.34 at the beginning of the year. Since then, MDGL stock has decreased by 9.1% and is now trading at $529.09.

Madrigal Pharmaceuticals, Inc. (NASDAQ:MDGL) posted its quarterly earnings data on Thursday, July, 30th. The biopharmaceutical company reported ($1.99) EPS for the quarter, topping the consensus estimate of ($2.68) by $0.69. The company's quarterly revenue was up 71.2% on a year-over-year basis.
Read the conference call transcript
.

Top institutional shareholders of Madrigal Pharmaceuticals include Jupiter Topco LLC (8.38%), Paulson & CO. Inc. (5.80%), BlackRock Inc. (5.20%) and Wellington Management Group LLP (3.57%). Insiders that own company stock include Bros Advisors Lp Baker, Rebecca Taub, William John Sibold, Paul A Friedman, Richard S Levy, Brian Joseph Lynch, Carole Huntsman, Mardi Dier, Shannon T Kelley, Fred B Craves, David Soergel, Robert E Waltermire, Kenneth Bate and James M Daly.
View institutional ownership trends
.

Shares of MDGL stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

Based on aggregate information from My MarketBeat watchlists, some other companies that Madrigal Pharmaceuticals investors own include American Water Works (AWK), Voyager Therapeutics (VYGR), Waste Connections (WCN), DiamondRock Hospitality (DRH), The RMR Group (RMR), Humana (HUM) and AUO (AUOTY).

Company Calendar

Last Earnings
7/30/2026
Today
9/17/2026
Next Earnings (Estimated)
11/03/2026
Fiscal Year End
12/31/2026

Industry, Sector and Symbol

Stock Exchange
NASDAQ
Industry
Biotechnology
Sub-Industry
Biotechnology
Current Symbol
NASDAQ:MDGL
CIK
1157601
Employees
915
Year Founded
2011

Price Target and Rating

High Price Target
$962.00
Low Price Target
$542.00
Potential Upside/Downside
+32.2%
Consensus Rating
Moderate Buy
Rating Score (0-4)
2.78
Research Coverage
18 Analysts

Profitability

EPS (Trailing Twelve Months)
($12.89)
Trailing P/E Ratio
N/A
Forward P/E Ratio
N/A
P/E Growth
N/A
Net Income
-$288.28 million
Net Margins
-25.32%
Pretax Margin
-25.32%
Return on Equity
-56.65%
Return on Assets
-25.53%

Debt

Debt-to-Equity Ratio
0.65
Current Ratio
3.20
Quick Ratio
2.94

Sales & Book Value

Annual Sales
$958.40 million
Price / Sales
12.75
Cash Flow
N/A
Price / Cash Flow
N/A
Book Value
$26.54 per share
Price / Book
19.94

Miscellaneous

Outstanding Shares
23,100,000
Free Float
19,038,000
Market Cap
$12.22 billion
Optionable
Optionable
Beta
-0.98

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This page (NASDAQ:MDGL) was last updated on 9/17/2026 by MarketBeat.com Staff.
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