Avalo Therapeutics (AVTX) Competitors $11.70 -0.13 (-1.10%) Closing price 09/22/2025 04:00 PM EasternExtended Trading$11.56 -0.15 (-1.24%) As of 09/22/2025 07:53 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOwnershipSEC FilingsShort InterestTrendsBuy This Stock AVTX vs. PRME, IVA, OLMA, AQST, CMPS, CMPX, BCYC, KOD, ETON, and ARCTShould you be buying Avalo Therapeutics stock or one of its competitors? The main competitors of Avalo Therapeutics include Prime Medicine (PRME), Inventiva (IVA), Olema Pharmaceuticals (OLMA), Aquestive Therapeutics (AQST), COMPASS Pathways (CMPS), Compass Therapeutics (CMPX), Bicycle Therapeutics (BCYC), Kodiak Sciences (KOD), Eton Pharmaceuticals (ETON), and Arcturus Therapeutics (ARCT). These companies are all part of the "pharmaceutical products" industry. Avalo Therapeutics vs. Its Competitors Prime Medicine Inventiva Olema Pharmaceuticals Aquestive Therapeutics COMPASS Pathways Compass Therapeutics Bicycle Therapeutics Kodiak Sciences Eton Pharmaceuticals Arcturus Therapeutics Avalo Therapeutics (NASDAQ:AVTX) and Prime Medicine (NASDAQ:PRME) are both small-cap pharmaceutical products companies, but which is the better investment? We will compare the two businesses based on the strength of their media sentiment, risk, profitability, dividends, analyst recommendations, earnings, institutional ownership and valuation. Is AVTX or PRME more profitable? Avalo Therapeutics has a net margin of 0.00% compared to Prime Medicine's net margin of -4,016.83%. Avalo Therapeutics' return on equity of -48.48% beat Prime Medicine's return on equity.Company Net Margins Return on Equity Return on Assets Avalo TherapeuticsN/A -48.48% -35.94% Prime Medicine -4,016.83%-156.16%-64.41% Which has more risk and volatility, AVTX or PRME? Avalo Therapeutics has a beta of 0.88, meaning that its stock price is 12% less volatile than the S&P 500. Comparatively, Prime Medicine has a beta of 2.39, meaning that its stock price is 139% more volatile than the S&P 500. Which has preferable earnings and valuation, AVTX or PRME? Avalo Therapeutics has higher earnings, but lower revenue than Prime Medicine. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioAvalo Therapeutics$440K349.67-$35.13MN/AN/APrime Medicine$2.98M225.34-$195.88M-$1.56-3.20 Do analysts prefer AVTX or PRME? Avalo Therapeutics currently has a consensus price target of $31.67, suggesting a potential upside of 170.66%. Given Avalo Therapeutics' stronger consensus rating and higher probable upside, research analysts plainly believe Avalo Therapeutics is more favorable than Prime Medicine.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Avalo Therapeutics 0 Sell rating(s) 0 Hold rating(s) 9 Buy rating(s) 0 Strong Buy rating(s) 3.00Prime Medicine 0 Sell rating(s) 0 Hold rating(s) 0 Buy rating(s) 0 Strong Buy rating(s) 0.00 Do institutionals and insiders hold more shares of AVTX or PRME? 87.1% of Avalo Therapeutics shares are owned by institutional investors. Comparatively, 70.4% of Prime Medicine shares are owned by institutional investors. 0.3% of Avalo Therapeutics shares are owned by company insiders. Comparatively, 22.7% of Prime Medicine shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock is poised for long-term growth. Does the media favor AVTX or PRME? In the previous week, Avalo Therapeutics had 3 more articles in the media than Prime Medicine. MarketBeat recorded 11 mentions for Avalo Therapeutics and 8 mentions for Prime Medicine. Avalo Therapeutics' average media sentiment score of 0.72 beat Prime Medicine's score of 0.24 indicating that Avalo Therapeutics is being referred to more favorably in the media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Avalo Therapeutics 4 Very Positive mention(s) 1 Positive mention(s) 5 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Prime Medicine 1 Very Positive mention(s) 2 Positive mention(s) 5 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Neutral SummaryAvalo Therapeutics beats Prime Medicine on 11 of the 14 factors compared between the two stocks. 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New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding AVTX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart AVTX vs. The Competition Export to ExcelMetricAvalo TherapeuticsMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$155.59M$2.57B$5.80B$10.46BDividend YieldN/A55.05%5.61%4.57%P/E RatioN/A23.06348.5626.86Price / Sales349.67712.83549.90125.65Price / CashN/A27.8326.0131.15Price / Book0.915.3615.536.50Net Income-$35.13M$32.95M$3.29B$271.25M7 Day Performance15.38%3.96%200.87%3.69%1 Month Performance18.42%5.27%184.38%8.07%1 Year Performance20.37%-0.72%325.51%29.65% Avalo Therapeutics Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)AVTXAvalo Therapeutics3.9594 of 5 stars$11.70-1.1%$31.67+170.7%+20.4%$155.59M$440K0.0040Gap DownPRMEPrime Medicine0.4801 of 5 stars$4.01-1.5%N/AN/A$547.72M$2.98M0.00N/AIVAInventiva3.0857 of 5 stars$5.31-5.3%$14.83+179.3%+193.7%$536.67M$9.95M0.00100Upcoming EarningsGap UpOLMAOlema Pharmaceuticals2.7404 of 5 stars$8.00+3.0%$24.00+200.0%-38.8%$533.29MN/A-4.0470AQSTAquestive Therapeutics1.8829 of 5 stars$5.14+1.8%$10.29+100.1%+1.6%$503.61M$44.13M-7.34160News CoverageOptions VolumeCMPSCOMPASS Pathways2.9724 of 5 stars$5.14-1.2%$16.29+216.8%-30.5%$498.89MN/A-2.79120Positive NewsCMPXCompass Therapeutics1.9106 of 5 stars$3.69+3.4%$13.88+276.0%+110.2%$493.67M$850K-8.2020BCYCBicycle Therapeutics3.1037 of 5 stars$6.86-3.0%$22.22+223.9%-71.9%$490M$19.28M-1.95240KODKodiak Sciences2.6225 of 5 stars$9.35+1.1%$11.75+25.7%+468.6%$488.60MN/A-2.4690News CoverageAnalyst ForecastGap UpETONEton Pharmaceuticals2.1652 of 5 stars$17.78+0.7%$29.67+66.9%+238.9%$473.34M$58.18M-111.1320News CoveragePositive NewsARCTArcturus Therapeutics2.9377 of 5 stars$18.13+4.7%$50.57+178.9%+2.0%$470.32M$152.31M-8.13180Positive News Related Companies and Tools Related Companies Prime Medicine Competitors Inventiva Competitors Olema Pharmaceuticals Competitors Aquestive Therapeutics Competitors COMPASS Pathways Competitors Compass Therapeutics Competitors Bicycle Therapeutics Competitors Kodiak Sciences Competitors Eton Pharmaceuticals Competitors Arcturus Therapeutics Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:AVTX) was last updated on 9/23/2025 by MarketBeat.com Staff From Our PartnersTrump’s national nightmare is herePorter Stansberry and Jeff Brown say a new U.S. national emergency is already underway — and it could trigger ...Porter & Company | SponsoredHe Called Nvidia at $1.10. 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