Avalo Therapeutics (AVTX) Competitors $4.78 -0.12 (-2.45%) Closing price 07/11/2025 04:00 PM EasternExtended Trading$4.99 +0.21 (+4.29%) As of 07/11/2025 07:47 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOwnershipSEC FilingsShort InterestTrendsBuy This Stock AVTX vs. SOPH, MNPR, SCPH, DSGN, VOR, ACIU, ESPR, PROK, KOD, and SLSShould you be buying Avalo Therapeutics stock or one of its competitors? The main competitors of Avalo Therapeutics include SOPHiA GENETICS (SOPH), Monopar Therapeutics (MNPR), scPharmaceuticals (SCPH), Design Therapeutics (DSGN), Vor Biopharma (VOR), AC Immune (ACIU), Esperion Therapeutics (ESPR), ProKidney (PROK), Kodiak Sciences (KOD), and SELLAS Life Sciences Group (SLS). These companies are all part of the "pharmaceutical products" industry. Avalo Therapeutics vs. Its Competitors SOPHiA GENETICS Monopar Therapeutics scPharmaceuticals Design Therapeutics Vor Biopharma AC Immune Esperion Therapeutics ProKidney Kodiak Sciences SELLAS Life Sciences Group Avalo Therapeutics (NASDAQ:AVTX) and SOPHiA GENETICS (NASDAQ:SOPH) are both small-cap medical companies, but which is the better business? We will contrast the two companies based on the strength of their institutional ownership, earnings, media sentiment, valuation, profitability, dividends, risk and analyst recommendations. Which has stronger earnings & valuation, AVTX or SOPH? Avalo Therapeutics has higher earnings, but lower revenue than SOPHiA GENETICS. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioAvalo Therapeutics$440K117.65-$35.13MN/AN/ASOPHiA GENETICS$65.17M3.57-$62.49M-$1.00-3.49 Do analysts prefer AVTX or SOPH? Avalo Therapeutics currently has a consensus price target of $30.00, indicating a potential upside of 527.62%. SOPHiA GENETICS has a consensus price target of $7.00, indicating a potential upside of 100.57%. Given Avalo Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe Avalo Therapeutics is more favorable than SOPHiA GENETICS.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Avalo Therapeutics 0 Sell rating(s) 0 Hold rating(s) 6 Buy rating(s) 0 Strong Buy rating(s) 3.00SOPHiA GENETICS 0 Sell rating(s) 1 Hold rating(s) 2 Buy rating(s) 0 Strong Buy rating(s) 2.67 Does the media prefer AVTX or SOPH? In the previous week, Avalo Therapeutics had 1 more articles in the media than SOPHiA GENETICS. MarketBeat recorded 3 mentions for Avalo Therapeutics and 2 mentions for SOPHiA GENETICS. SOPHiA GENETICS's average media sentiment score of 0.94 beat Avalo Therapeutics' score of 0.63 indicating that SOPHiA GENETICS is being referred to more favorably in the news media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Avalo Therapeutics 0 Very Positive mention(s) 0 Positive mention(s) 2 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive SOPHiA GENETICS 0 Very Positive mention(s) 0 Positive mention(s) 1 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Is AVTX or SOPH more profitable? Avalo Therapeutics has a net margin of 0.00% compared to SOPHiA GENETICS's net margin of -98.51%. Avalo Therapeutics' return on equity of 111.00% beat SOPHiA GENETICS's return on equity.Company Net Margins Return on Equity Return on Assets Avalo TherapeuticsN/A 111.00% 58.88% SOPHiA GENETICS -98.51%-63.47%-40.06% Do insiders & institutionals have more ownership in AVTX or SOPH? 87.1% of Avalo Therapeutics shares are held by institutional investors. Comparatively, 31.6% of SOPHiA GENETICS shares are held by institutional investors. 3.0% of Avalo Therapeutics shares are held by company insiders. Comparatively, 4.9% of SOPHiA GENETICS shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term. Which has more risk and volatility, AVTX or SOPH? Avalo Therapeutics has a beta of 0.77, meaning that its share price is 23% less volatile than the S&P 500. Comparatively, SOPHiA GENETICS has a beta of 1, meaning that its share price has a similar volatility profile to the S&P 500. SummaryAvalo Therapeutics beats SOPHiA GENETICS on 10 of the 14 factors compared between the two stocks. Get Avalo Therapeutics News Delivered to You Automatically Sign up to receive the latest news and ratings for AVTX and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding AVTX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart AVTX vs. The Competition Export to ExcelMetricAvalo TherapeuticsMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$53.06M$2.74B$5.62B$9.10BDividend YieldN/A1.79%5.24%4.00%P/E RatioN/A9.4228.1820.27Price / Sales117.65714.14428.7098.48Price / CashN/A165.3637.4658.16Price / Book0.374.608.045.49Net Income-$35.13M$31.26M$3.19B$250.45M7 Day Performance-4.59%4.80%3.62%4.79%1 Month Performance-2.05%5.42%4.06%7.68%1 Year Performance-60.69%-4.36%30.00%16.43% Avalo Therapeutics Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)AVTXAvalo Therapeutics3.0138 of 5 stars$4.78-2.4%$30.00+527.6%-60.2%$53.06M$440K0.0040News CoverageSOPHSOPHiA GENETICS2.7467 of 5 stars$3.10+0.3%$7.00+125.8%-25.9%$206.06M$65.17M-3.10520Positive NewsMNPRMonopar Therapeutics2.0345 of 5 stars$35.78+6.5%$56.50+57.9%+924.0%$205.47MN/A-10.2810Analyst RevisionSCPHscPharmaceuticals4.5058 of 5 stars$3.81-1.6%$14.00+267.5%-4.8%$204.30M$36.33M-1.9930Positive NewsDSGNDesign Therapeutics0.637 of 5 stars$3.37-5.6%$4.00+18.7%-7.5%$202.66MN/A-3.4040News CoveragePositive NewsVORVor Biopharma3.9134 of 5 stars$1.62+52.8%$5.63+247.4%+155.2%$202.44MN/A-0.98140Options VolumeHigh Trading VolumeACIUAC Immune2.2522 of 5 stars$2.03+1.0%$12.00+491.1%-42.5%$201.82M$31.02M-3.50140Analyst RevisionESPREsperion Therapeutics4.0161 of 5 stars$0.98-0.9%$7.00+611.1%-52.2%$196.93M$332.31M-1.23200News CoverageAnalyst RevisionPROKProKidney2.6633 of 5 stars$0.59-11.5%$3.50+491.1%+89.2%$195.73M$80K-0.993News CoverageAnalyst ForecastInsider TradeGap DownHigh Trading VolumeKODKodiak Sciences4.0954 of 5 stars$3.73+0.8%$9.00+141.3%+64.1%$195.23MN/A-1.0390News CoverageSLSSELLAS Life Sciences Group0.3439 of 5 stars$2.19+12.3%N/A+60.0%$194.57M$1M-5.7610High Trading Volume Related Companies and Tools Related Companies SOPHiA GENETICS Competitors Monopar Therapeutics Competitors scPharmaceuticals Competitors Design Therapeutics Competitors Vor Biopharma Competitors AC Immune Competitors Esperion Therapeutics Competitors ProKidney Competitors Kodiak Sciences Competitors SELLAS Life Sciences Group Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:AVTX) was last updated on 7/12/2025 by MarketBeat.com Staff From Our PartnersThis Signal Only Flashes Once Every 4 Years – And It Just TriggeredThis same signal has appeared twice before in the past 8 years — both times, it kicked off major moves in cryp...Crypto Swap Profits | SponsoredI was wrong about TrumpI made a mistake. 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