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ProKidney (PROK) Competitors

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$1.40 -0.08 (-5.07%)
Closing price 08/13/2026 04:00 PM Eastern
Extended Trading
$1.44 +0.03 (+2.14%)
As of 08:45 AM Eastern
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PROK vs. IOVA, TYRA, MESO, AUPH, and AGIO

Should you buy ProKidney stock or one of its competitors? ProKidney's main competitors and comparable companies include Iovance Biotherapeutics (IOVA), Tyra Biosciences (TYRA), Mesoblast (MESO), Aurinia Pharmaceuticals (AUPH), and Agios Pharmaceuticals (AGIO). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does ProKidney compare to Iovance Biotherapeutics?

Iovance Biotherapeutics (NASDAQ:IOVA) and ProKidney (NASDAQ:PROK) are both healthcare companies, but which is the better stock? We will compare the two companies based on the strength of their institutional ownership, analyst recommendations, valuation, profitability, dividends, earnings, media sentiment and risk.

In the previous week, Iovance Biotherapeutics and Iovance Biotherapeutics both had 17 articles in the media. Iovance Biotherapeutics' average media sentiment score of 0.75 beat ProKidney's score of -0.22 indicating that Iovance Biotherapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Iovance Biotherapeutics
3 Very Positive mention(s)
2 Positive mention(s)
5 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
ProKidney
2 Very Positive mention(s)
1 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Iovance Biotherapeutics has a beta of 0.71, meaning that its stock price is 29% less volatile than the broader market. Comparatively, ProKidney has a beta of 1.66, meaning that its stock price is 66% more volatile than the broader market.

ProKidney has lower revenue, but higher earnings than Iovance Biotherapeutics. Iovance Biotherapeutics is trading at a lower price-to-earnings ratio than ProKidney, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Iovance Biotherapeutics$324.97M9.09-$390.98M-$0.73N/A
ProKidney$890K476.85-$68.99M-$0.55N/A

Iovance Biotherapeutics has a net margin of -89.11% compared to ProKidney's net margin of -10,288.39%. ProKidney's return on equity of 0.00% beat Iovance Biotherapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Iovance Biotherapeutics-89.11% -40.92% -31.66%
ProKidney -10,288.39%N/A -25.76%

Iovance Biotherapeutics presently has a consensus target price of $8.00, suggesting a potential upside of 22.70%. ProKidney has a consensus target price of $12.00, suggesting a potential upside of 754.09%. Given ProKidney's stronger consensus rating and higher possible upside, analysts plainly believe ProKidney is more favorable than Iovance Biotherapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Iovance Biotherapeutics
2 Sell rating(s)
2 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.33
ProKidney
1 Sell rating(s)
1 Hold rating(s)
1 Buy rating(s)
1 Strong Buy rating(s)
2.50

77.0% of Iovance Biotherapeutics shares are held by institutional investors. Comparatively, 51.6% of ProKidney shares are held by institutional investors. 7.8% of Iovance Biotherapeutics shares are held by company insiders. Comparatively, 39.8% of ProKidney shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company will outperform the market over the long term.

Summary

ProKidney beats Iovance Biotherapeutics on 11 of the 16 factors compared between the two stocks.

How does ProKidney compare to Tyra Biosciences?

Tyra Biosciences (NASDAQ:TYRA) and ProKidney (NASDAQ:PROK) are both small-cap healthcare companies, but which is the better investment? We will contrast the two businesses based on the strength of their earnings, profitability, dividends, risk, valuation, analyst recommendations, media sentiment and institutional ownership.

ProKidney has higher revenue and earnings than Tyra Biosciences. Tyra Biosciences is trading at a lower price-to-earnings ratio than ProKidney, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Tyra BiosciencesN/AN/A-$119.95M-$2.40N/A
ProKidney$890K476.85-$68.99M-$0.55N/A

Tyra Biosciences has a beta of 0.77, indicating that its stock price is 23% less volatile than the broader market. Comparatively, ProKidney has a beta of 1.66, indicating that its stock price is 66% more volatile than the broader market.

Tyra Biosciences presently has a consensus target price of $46.90, indicating a potential upside of 87.45%. ProKidney has a consensus target price of $12.00, indicating a potential upside of 754.09%. Given ProKidney's higher possible upside, analysts clearly believe ProKidney is more favorable than Tyra Biosciences.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Tyra Biosciences
1 Sell rating(s)
1 Hold rating(s)
12 Buy rating(s)
1 Strong Buy rating(s)
2.87
ProKidney
1 Sell rating(s)
1 Hold rating(s)
1 Buy rating(s)
1 Strong Buy rating(s)
2.50

Tyra Biosciences has a net margin of 0.00% compared to ProKidney's net margin of -10,288.39%. ProKidney's return on equity of 0.00% beat Tyra Biosciences' return on equity.

Company Net Margins Return on Equity Return on Assets
Tyra BiosciencesN/A -46.39% -43.07%
ProKidney -10,288.39%N/A -25.76%

84.1% of Tyra Biosciences shares are held by institutional investors. Comparatively, 51.6% of ProKidney shares are held by institutional investors. 12.5% of Tyra Biosciences shares are held by insiders. Comparatively, 39.8% of ProKidney shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

In the previous week, ProKidney had 14 more articles in the media than Tyra Biosciences. MarketBeat recorded 17 mentions for ProKidney and 3 mentions for Tyra Biosciences. ProKidney's average media sentiment score of -0.22 beat Tyra Biosciences' score of -0.38 indicating that ProKidney is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Tyra Biosciences
0 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
ProKidney
2 Very Positive mention(s)
1 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Summary

ProKidney beats Tyra Biosciences on 11 of the 15 factors compared between the two stocks.

How does ProKidney compare to Mesoblast?

Mesoblast (NASDAQ:MESO) and ProKidney (NASDAQ:PROK) are both healthcare companies, but which is the superior investment? We will compare the two businesses based on the strength of their earnings, risk, institutional ownership, dividends, profitability, valuation, media sentiment and analyst recommendations.

Mesoblast has a net margin of 0.00% compared to ProKidney's net margin of -10,288.39%.

Company Net Margins Return on Equity Return on Assets
MesoblastN/A N/A N/A
ProKidney -10,288.39%N/A -25.76%

ProKidney has lower revenue, but higher earnings than Mesoblast. Mesoblast is trading at a lower price-to-earnings ratio than ProKidney, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Mesoblast$17.20M124.52-$102.14M-$0.28N/A
ProKidney$890K476.85-$68.99M-$0.55N/A

1.4% of Mesoblast shares are owned by institutional investors. Comparatively, 51.6% of ProKidney shares are owned by institutional investors. 18.8% of Mesoblast shares are owned by insiders. Comparatively, 39.8% of ProKidney shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company will outperform the market over the long term.

In the previous week, ProKidney had 14 more articles in the media than Mesoblast. MarketBeat recorded 17 mentions for ProKidney and 3 mentions for Mesoblast. Mesoblast's average media sentiment score of 0.86 beat ProKidney's score of -0.22 indicating that Mesoblast is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Mesoblast
1 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive
ProKidney
2 Very Positive mention(s)
1 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Mesoblast has a beta of 2.08, indicating that its stock price is 108% more volatile than the broader market. Comparatively, ProKidney has a beta of 1.66, indicating that its stock price is 66% more volatile than the broader market.

ProKidney has a consensus target price of $12.00, suggesting a potential upside of 754.09%. Given ProKidney's stronger consensus rating and higher possible upside, analysts plainly believe ProKidney is more favorable than Mesoblast.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Mesoblast
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00
ProKidney
1 Sell rating(s)
1 Hold rating(s)
1 Buy rating(s)
1 Strong Buy rating(s)
2.50

Summary

ProKidney beats Mesoblast on 10 of the 16 factors compared between the two stocks.

How does ProKidney compare to Aurinia Pharmaceuticals?

Aurinia Pharmaceuticals (NASDAQ:AUPH) and ProKidney (NASDAQ:PROK) are both healthcare companies, but which is the better investment? We will contrast the two companies based on the strength of their media sentiment, institutional ownership, dividends, earnings, risk, analyst recommendations, valuation and profitability.

Aurinia Pharmaceuticals currently has a consensus price target of $17.67, suggesting a potential upside of 16.38%. ProKidney has a consensus price target of $12.00, suggesting a potential upside of 754.09%. Given ProKidney's stronger consensus rating and higher possible upside, analysts plainly believe ProKidney is more favorable than Aurinia Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Aurinia Pharmaceuticals
0 Sell rating(s)
5 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.17
ProKidney
1 Sell rating(s)
1 Hold rating(s)
1 Buy rating(s)
1 Strong Buy rating(s)
2.50

In the previous week, ProKidney had 11 more articles in the media than Aurinia Pharmaceuticals. MarketBeat recorded 17 mentions for ProKidney and 6 mentions for Aurinia Pharmaceuticals. Aurinia Pharmaceuticals' average media sentiment score of 0.48 beat ProKidney's score of -0.22 indicating that Aurinia Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Aurinia Pharmaceuticals
1 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral
ProKidney
2 Very Positive mention(s)
1 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Aurinia Pharmaceuticals has a beta of 1.42, suggesting that its stock price is 42% more volatile than the broader market. Comparatively, ProKidney has a beta of 1.66, suggesting that its stock price is 66% more volatile than the broader market.

Aurinia Pharmaceuticals has higher revenue and earnings than ProKidney. ProKidney is trading at a lower price-to-earnings ratio than Aurinia Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Aurinia Pharmaceuticals$311.51M6.48$287.20M$2.296.63
ProKidney$890K476.85-$68.99M-$0.55N/A

Aurinia Pharmaceuticals has a net margin of 100.84% compared to ProKidney's net margin of -10,288.39%. Aurinia Pharmaceuticals' return on equity of 26.11% beat ProKidney's return on equity.

Company Net Margins Return on Equity Return on Assets
Aurinia Pharmaceuticals100.84% 26.11% 19.89%
ProKidney -10,288.39%N/A -25.76%

36.8% of Aurinia Pharmaceuticals shares are owned by institutional investors. Comparatively, 51.6% of ProKidney shares are owned by institutional investors. 10.4% of Aurinia Pharmaceuticals shares are owned by company insiders. Comparatively, 39.8% of ProKidney shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

Summary

Aurinia Pharmaceuticals and ProKidney tied by winning 8 of the 16 factors compared between the two stocks.

How does ProKidney compare to Agios Pharmaceuticals?

Agios Pharmaceuticals (NASDAQ:AGIO) and ProKidney (NASDAQ:PROK) are both healthcare companies, but which is the superior stock? We will contrast the two companies based on the strength of their media sentiment, profitability, dividends, valuation, institutional ownership, analyst recommendations, earnings and risk.

ProKidney has lower revenue, but higher earnings than Agios Pharmaceuticals. Agios Pharmaceuticals is trading at a lower price-to-earnings ratio than ProKidney, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Agios Pharmaceuticals$54.03M36.98-$412.78M-$7.01N/A
ProKidney$890K476.85-$68.99M-$0.55N/A

Agios Pharmaceuticals has a net margin of -418.24% compared to ProKidney's net margin of -10,288.39%. ProKidney's return on equity of 0.00% beat Agios Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Agios Pharmaceuticals-418.24% -35.67% -33.06%
ProKidney -10,288.39%N/A -25.76%

Agios Pharmaceuticals has a beta of 0.58, meaning that its stock price is 42% less volatile than the broader market. Comparatively, ProKidney has a beta of 1.66, meaning that its stock price is 66% more volatile than the broader market.

Agios Pharmaceuticals currently has a consensus price target of $41.25, indicating a potential upside of 23.24%. ProKidney has a consensus price target of $12.00, indicating a potential upside of 754.09%. Given ProKidney's stronger consensus rating and higher possible upside, analysts clearly believe ProKidney is more favorable than Agios Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Agios Pharmaceuticals
1 Sell rating(s)
4 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.40
ProKidney
1 Sell rating(s)
1 Hold rating(s)
1 Buy rating(s)
1 Strong Buy rating(s)
2.50

51.6% of ProKidney shares are owned by institutional investors. 5.4% of Agios Pharmaceuticals shares are owned by company insiders. Comparatively, 39.8% of ProKidney shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term.

In the previous week, ProKidney had 9 more articles in the media than Agios Pharmaceuticals. MarketBeat recorded 17 mentions for ProKidney and 8 mentions for Agios Pharmaceuticals. Agios Pharmaceuticals' average media sentiment score of 0.90 beat ProKidney's score of -0.22 indicating that Agios Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Agios Pharmaceuticals
2 Very Positive mention(s)
0 Positive mention(s)
4 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
ProKidney
2 Very Positive mention(s)
1 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Summary

ProKidney beats Agios Pharmaceuticals on 13 of the 17 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding PROK and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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PROK vs. The Competition

MetricProKidneyBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$447.05M$3.75B$7.07B$13.00B
Dividend YieldN/A3.76%2.58%10.72%
P/E Ratio-2.5510.24269.6325.21
Price / Sales476.851,291.38596.7299.91
Price / CashN/A103.0170.5350.75
Price / Book-0.4217.6813.116.24
Net Income-$68.99M-$13.30M$3.45B$347.70M
7 Day Performance-14.33%0.65%0.78%0.87%
1 Month Performance-9.35%0.50%1.45%0.90%
1 Year Performance-41.94%54.56%67.07%20.13%

ProKidney Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
PROK
ProKidney
1.8889 of 5 stars
$1.41
-5.1%
$12.00
+754.1%
-40.7%$447.05M$890KN/A3
IOVA
Iovance Biotherapeutics
2.6125 of 5 stars
$4.34
-0.5%
$8.43
+94.2%
+165.6%$1.95B$263.50MN/A500
TYRA
Tyra Biosciences
2.619 of 5 stars
$25.71
-21.0%
$46.90
+82.4%
+132.7%$1.93BN/AN/A20
MESO
Mesoblast
0.2685 of 5 stars
$14.97
+1.1%
N/A+8.6%$1.92B$17.20MN/A80
AUPH
Aurinia Pharmaceuticals
3.7173 of 5 stars
$15.19
+1.7%
$17.33
+14.1%
+26.4%$1.92B$283.05M7.00300

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This page (NASDAQ:PROK) was last updated on 8/14/2026 by MarketBeat.com Staff.
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