Biofrontera (BFRI) Competitors $1.06 -0.05 (-4.07%) Closing price 07/25/2025 03:48 PM EasternExtended Trading$1.02 -0.04 (-3.30%) As of 07/25/2025 07:13 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesOwnershipSEC FilingsShort InterestTrendsBuy This Stock BFRI vs. CALC, ESLA, SCYX, SNYR, FGEN, CLNN, SONN, ENLV, GBIO, and DYAIShould you be buying Biofrontera stock or one of its competitors? The main competitors of Biofrontera include CalciMedica (CALC), Estrella Immunopharma (ESLA), SCYNEXIS (SCYX), Synergy CHC (SNYR), FibroGen (FGEN), Clene (CLNN), Sonnet BioTherapeutics (SONN), Enlivex Therapeutics (ENLV), Generation Bio (GBIO), and Dyadic International (DYAI). These companies are all part of the "pharmaceutical products" industry. Biofrontera vs. Its Competitors CalciMedica Estrella Immunopharma SCYNEXIS Synergy CHC FibroGen Clene Sonnet BioTherapeutics Enlivex Therapeutics Generation Bio Dyadic International CalciMedica (NASDAQ:CALC) and Biofrontera (NASDAQ:BFRI) are both small-cap medical companies, but which is the better business? We will contrast the two businesses based on the strength of their earnings, media sentiment, risk, valuation, profitability, analyst recommendations, institutional ownership and dividends. Is CALC or BFRI more profitable? CalciMedica has a net margin of 0.00% compared to Biofrontera's net margin of -30.33%. CalciMedica's return on equity of -171.81% beat Biofrontera's return on equity.Company Net Margins Return on Equity Return on Assets CalciMedicaN/A -171.81% -100.43% Biofrontera -30.33%-305.13%-82.67% Do analysts rate CALC or BFRI? CalciMedica presently has a consensus target price of $16.00, indicating a potential upside of 321.05%. Biofrontera has a consensus target price of $2.75, indicating a potential upside of 159.43%. Given CalciMedica's higher probable upside, analysts clearly believe CalciMedica is more favorable than Biofrontera.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score CalciMedica 0 Sell rating(s) 0 Hold rating(s) 1 Buy rating(s) 0 Strong Buy rating(s) 3.00Biofrontera 0 Sell rating(s) 0 Hold rating(s) 1 Buy rating(s) 0 Strong Buy rating(s) 3.00 Which has stronger valuation and earnings, CALC or BFRI? CalciMedica has higher earnings, but lower revenue than Biofrontera. CalciMedica is trading at a lower price-to-earnings ratio than Biofrontera, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioCalciMedicaN/AN/A-$13.70M-$1.56-2.44Biofrontera$37.32M0.29-$17.76M-$2.26-0.47 Do institutionals & insiders believe in CALC or BFRI? 10.1% of Biofrontera shares are owned by institutional investors. 41.6% of CalciMedica shares are owned by insiders. Comparatively, 1.2% of Biofrontera shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth. Which has more risk & volatility, CALC or BFRI? CalciMedica has a beta of 1.24, indicating that its stock price is 24% more volatile than the S&P 500. Comparatively, Biofrontera has a beta of 0.43, indicating that its stock price is 57% less volatile than the S&P 500. Does the media refer more to CALC or BFRI? In the previous week, CalciMedica had 2 more articles in the media than Biofrontera. MarketBeat recorded 3 mentions for CalciMedica and 1 mentions for Biofrontera. Biofrontera's average media sentiment score of 1.87 beat CalciMedica's score of 1.45 indicating that Biofrontera is being referred to more favorably in the news media. Company Overall Sentiment CalciMedica Positive Biofrontera Very Positive SummaryCalciMedica beats Biofrontera on 8 of the 13 factors compared between the two stocks. Get Biofrontera News Delivered to You Automatically Sign up to receive the latest news and ratings for BFRI and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding BFRI and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart BFRI vs. The Competition Export to ExcelMetricBiofronteraMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$11.20M$3.05B$5.70B$9.50BDividend YieldN/A2.37%4.58%4.00%P/E Ratio-0.4721.3228.3920.08Price / Sales0.29285.38431.7689.31Price / CashN/A42.7636.2258.56Price / Book1.868.378.675.88Net Income-$17.76M-$55.19M$3.25B$258.89M7 Day Performance20.15%5.86%4.25%3.71%1 Month Performance69.63%17.29%10.51%11.72%1 Year Performance-14.52%4.39%35.68%18.01% Biofrontera Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)BFRIBiofrontera3.0382 of 5 stars$1.06-4.1%$2.75+159.4%-3.6%$11.20M$37.32M-0.4770Gap UpCALCCalciMedica3.288 of 5 stars$2.05-11.6%$16.00+680.5%-2.1%$32.42MN/A0.0030Positive NewsESLAEstrella Immunopharma3.2056 of 5 stars$0.84-5.5%$16.00+1,813.9%-47.9%$32.01MN/A0.00N/ANews CoveragePositive NewsGap DownSCYXSCYNEXIS0.8915 of 5 stars$0.76-7.2%N/A-65.0%$31.96M$3.75M-1.3660Positive NewsSNYRSynergy CHC4.0752 of 5 stars$3.40+0.3%$10.00+194.1%N/A$31.17M$34.83M0.0040FGENFibroGen4.5924 of 5 stars$7.32-4.8%$250.00+3,315.3%-75.8%$31.08M$29.62M-2.93570Positive NewsCLNNClene3.4594 of 5 stars$3.70-0.8%$40.00+981.1%-18.2%$30.84M$340K-0.92100SONNSonnet BioTherapeutics3.9604 of 5 stars$9.77+1.3%$20.00+104.7%-41.3%$30.52M$20K0.0010Positive NewsGap DownHigh Trading VolumeENLVEnlivex Therapeutics2.7974 of 5 stars$1.23-3.9%$10.00+713.0%-19.3%$30.27MN/A-1.8670News CoverageAnalyst ForecastGap UpGBIOGeneration Bio4.0251 of 5 stars$0.43-3.2%$7.33+1,621.4%-86.5%$29.50M$19.89M-0.39150Analyst DowngradeStock SplitHigh Trading VolumeDYAIDyadic International3.2941 of 5 stars$0.98+1.1%$6.00+512.1%-22.0%$29.19M$3.49M-4.907Positive NewsGap Up Related Companies and Tools Related Companies CALC Competitors ESLA Competitors SCYX Competitors SNYR Competitors FGEN Competitors CLNN Competitors SONN Competitors ENLV Competitors GBIO Competitors DYAI Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:BFRI) was last updated on 7/26/2025 by MarketBeat.com Staff From Our PartnersWhy AMZN, GOOG, MSFT might destroy NVDAInvesting Legend Hints the End May be Near for These 3 Iconic Stocks Futurist Eric Fry say Amazon, Tesla an...InvestorPlace | SponsoredCritical AI announcement set to ignite AI 2.0 I just put together an urgent new presentation that you need to see right away. In short: I believe we are...Timothy Sykes | SponsoredA new rule goes live in July — and the banks are quietly cashing inA little-known regulation quietly goes into effect this July. And it's already being exploited by Wall Stre...American Alternative | SponsoredTrump’s $100 Trillion Land Rush Is OnWhat Is "The US: IPO"? You won't hear this on CNBC... but the government may soon open up hundreds of trill...Stansberry Research | SponsoredBREAKING: The House just passed 3 pro-crypto bills!THREE pro-crypto bills just passed the House! Now, experts believe altcoin season is officially here. Crypto 101 Media | Sponsored[Shocking New Report] U.S. Dollar To Crash?The "Death Spiral" Threatening Your Savings But this time, it's not just Dalio ringing the alarm bells…GoldCo Precious Metals | SponsoredForget Nvidia, This “Ghost Town” Company Holds the Key to the AI BoomCold War Discovery Could Unlock $100 Trillion in Wealth Jeff recently traveled to an American ghost town to...Brownstone Research | SponsoredThe Robotics Revolution has arrived … and one $7 stock could take off as a result.Something big is brewing in Washington. According to my research, an executive order from President Trump c...Weiss Ratings | Sponsored Adding Choose a watchlist: Watchlist Adding You have already added ten stocks to your watchlist. Upgrade to MarketBeat All Access to add more stocks to your watchlist. Adding Biofrontera Inc. Please log in to your account or sign up in order to add this asset to your watchlist. Share Biofrontera With A Colleague Link copied to clipboard. Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. Start Your 30-Day Trial MarketBeat All Access Features Best-in-Class Portfolio Monitoring Get personalized stock ideas. Compare portfolio to indices. Check stock news, ratings, SEC filings, and more. Stock Ideas and Recommendations See daily stock ideas from top analysts. Receive short-term trading ideas from MarketBeat. Identify trending stocks on social media. Advanced Stock Screeners and Research Tools Use our seven stock screeners to find suitable stocks. Stay informed with MarketBeat's real-time news. Export data to Excel for personal analysis. Sign in to your free account to enjoy these benefits In-depth profiles and analysis for 20,000 public companies. Real-time analyst ratings, insider transactions, earnings data, and more. Our daily ratings and market update email newsletter. Sign in to your free account to enjoy all that MarketBeat has to offer. Sign In Create Account Your Email Address: Email Address Required Your Password: Password Required Log In or Sign in with Facebook Sign in with Google Forgot your password? Your Email Address: Please enter your email address. Please enter a valid email address Choose a Password: Please enter your password. Your password must be at least 8 characters long and contain at least 1 number, 1 letter, and 1 special character. Create My Account (Free) or Sign in with Facebook Sign in with Google By creating a free account, you agree to our terms of service. This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
