Castle Biosciences (CSTL) Competitors $24.01 +0.55 (+2.34%) Closing price 08/29/2025 04:00 PM EasternExtended Trading$24.01 0.00 (0.00%) As of 08/29/2025 05:18 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock CSTL vs. HTFL, CELC, ADUS, LFST, PGNY, ARDT, PACS, NHC, VRDN, and AVAHShould you be buying Castle Biosciences stock or one of its competitors? The main competitors of Castle Biosciences include Heartflow (HTFL), Celcuity (CELC), Addus HomeCare (ADUS), LifeStance Health Group (LFST), Progyny (PGNY), Ardent Health (ARDT), PACS Group (PACS), National HealthCare (NHC), Viridian Therapeutics (VRDN), and Aveanna Healthcare (AVAH). These companies are all part of the "healthcare" industry. Castle Biosciences vs. Its Competitors Heartflow Celcuity Addus HomeCare LifeStance Health Group Progyny Ardent Health PACS Group National HealthCare Viridian Therapeutics Aveanna Healthcare Heartflow (NASDAQ:HTFL) and Castle Biosciences (NASDAQ:CSTL) are both medical companies, but which is the better investment? We will contrast the two businesses based on the strength of their risk, profitability, media sentiment, valuation, dividends, earnings, institutional ownership and analyst recommendations. Which has higher earnings & valuation, HTFL or CSTL? Castle Biosciences has higher revenue and earnings than Heartflow. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioHeartflowN/AN/AN/AN/AN/ACastle Biosciences$332.07M2.10$18.25M-$0.35-68.60 Do analysts recommend HTFL or CSTL? Castle Biosciences has a consensus target price of $37.00, indicating a potential upside of 54.10%. Given Castle Biosciences' stronger consensus rating and higher probable upside, analysts clearly believe Castle Biosciences is more favorable than Heartflow.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Heartflow 0 Sell rating(s) 0 Hold rating(s) 0 Buy rating(s) 0 Strong Buy rating(s) 0.00Castle Biosciences 0 Sell rating(s) 1 Hold rating(s) 8 Buy rating(s) 0 Strong Buy rating(s) 2.89 Is HTFL or CSTL more profitable? Heartflow has a net margin of 0.00% compared to Castle Biosciences' net margin of -2.73%. Castle Biosciences' return on equity of 2.37% beat Heartflow's return on equity.Company Net Margins Return on Equity Return on Assets HeartflowN/A N/A N/A Castle Biosciences -2.73%2.37%2.03% Does the media prefer HTFL or CSTL? In the previous week, Castle Biosciences had 5 more articles in the media than Heartflow. MarketBeat recorded 7 mentions for Castle Biosciences and 2 mentions for Heartflow. Castle Biosciences' average media sentiment score of 1.35 beat Heartflow's score of 0.93 indicating that Castle Biosciences is being referred to more favorably in the news media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Heartflow 0 Very Positive mention(s) 0 Positive mention(s) 1 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Castle Biosciences 5 Very Positive mention(s) 0 Positive mention(s) 0 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Do insiders & institutionals have more ownership in HTFL or CSTL? 92.6% of Castle Biosciences shares are owned by institutional investors. 7.2% of Castle Biosciences shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock is poised for long-term growth. SummaryCastle Biosciences beats Heartflow on 10 of the 11 factors compared between the two stocks. Get Castle Biosciences News Delivered to You Automatically Sign up to receive the latest news and ratings for CSTL and its competitors with MarketBeat's FREE daily newsletter. Subscribe Now View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding CSTL and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart CSTL vs. The Competition Export to ExcelMetricCastle BiosciencesMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$696.49M$3.08B$5.69B$9.74BDividend YieldN/A2.28%6.64%4.48%P/E Ratio68.6020.9283.1926.59Price / Sales2.10352.35515.16159.07Price / Cash24.4043.5325.6628.92Price / Book1.479.7811.766.08Net Income$18.25M-$54.01M$3.27B$265.93M7 Day Performance16.72%0.10%1.13%0.36%1 Month Performance63.89%8.52%8.30%5.58%1 Year Performance-19.08%7.03%62.26%19.67% Castle Biosciences Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)CSTLCastle Biosciences2.5323 of 5 stars$24.01+2.3%$37.00+54.1%-19.1%$696.49M$332.07M68.60540News CoveragePositive NewsHTFLHeartflowN/A$29.84+2.3%N/AN/A$2.37BN/A0.00699CELCCelcuity1.7422 of 5 stars$49.25-6.0%$50.60+2.7%+221.0%$2.22BN/A-14.2840ADUSAddus HomeCare4.8951 of 5 stars$116.65-1.5%$138.38+18.6%-13.4%$2.18B$1.15B25.7549,703Positive NewsLFSTLifeStance Health Group3.3533 of 5 stars$5.39-2.9%$8.50+57.7%-13.2%$2.16B$1.25B-107.8010,218PGNYProgyny2.9606 of 5 stars$23.14-1.7%$25.10+8.5%+0.8%$2.02B$1.17B39.22310News CoveragePositive NewsARDTArdent Health3.4258 of 5 stars$12.70-2.2%$19.56+54.1%-36.0%$1.86B$5.97B7.0124,900Positive NewsPACSPACS Group2.8649 of 5 stars$11.75-2.5%$33.33+183.7%-70.7%$1.84B$3.56B0.0032,433NHCNational HealthCareN/A$111.98-2.5%N/A-17.2%$1.74B$1.46B14.0312,400Positive NewsVRDNViridian Therapeutics1.8746 of 5 stars$18.57-3.4%$37.78+103.4%+25.2%$1.57B$300K-4.8550News CoveragePositive NewsAVAHAveanna Healthcare2.3898 of 5 stars$7.43-0.5%$7.50+0.9%+41.6%$1.56B$2.02B92.8833,500Positive News Related Companies and Tools Related Companies Heartflow Alternatives Celcuity Alternatives Addus HomeCare Alternatives LifeStance Health Group Alternatives Progyny Alternatives Ardent Health Alternatives PACS Group Alternatives National HealthCare Alternatives Viridian Therapeutics Alternatives Aveanna Healthcare Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:CSTL) was last updated on 9/1/2025 by MarketBeat.com Staff From Our PartnersRetire Comfortably with These New Monthly Income ETFs?Too many retirees lie awake at night, worried their savings won’t last. 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