Which has stronger earnings and valuation, EDSA or RNA?

Avidity Biosciences is trading at a lower price-to-earnings ratio than Edesa Biotech, indicating that it is currently the more affordable of the two stocks. Company Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio Edesa Biotech N/A N/A -$7.19M -$1.69 N/A Avidity Biosciences N/A N/A N/A -$2.15 N/A

Is EDSA or RNA more profitable?

Avidity Biosciences' return on equity of 0.00% beat Edesa Biotech's return on equity. Company Net Margins Return on Equity Return on Assets Edesa Biotech N/A -560.22% -105.74% Avidity Biosciences N/A N/A N/A

Do analysts prefer EDSA or BNR?

Edesa Biotech currently has a consensus target price of $5.00, suggesting a potential upside of 29.53%. Given Edesa Biotech's stronger consensus rating and higher probable upside, equities research analysts plainly believe Edesa Biotech is more favorable than Burning Rock Biotech. Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Edesa Biotech 1 Sell rating(s) 0 Hold rating(s) 1 Buy rating(s) 1 Strong Buy rating(s) 2.67 Burning Rock Biotech 1 Sell rating(s) 0 Hold rating(s) 0 Buy rating(s) 0 Strong Buy rating(s) 1.00

Is EDSA or SPRB more profitable?

Spruce Biosciences' return on equity of -123.53% beat Edesa Biotech's return on equity. Company Net Margins Return on Equity Return on Assets Edesa Biotech N/A -560.22% -105.74% Spruce Biosciences N/A -123.53% -90.35%

Is EDSA or CLLS more profitable?

Edesa Biotech has a net margin of 0.00% compared to Cellectis' net margin of -102.34%. Cellectis' return on equity of -94.19% beat Edesa Biotech's return on equity. Company Net Margins Return on Equity Return on Assets Edesa Biotech N/A -560.22% -105.74% Cellectis -102.34% -94.19% -21.34%

Which has stronger valuation and earnings, EDSA or TNYA?

Edesa Biotech is trading at a lower price-to-earnings ratio than Tenaya Therapeutics, indicating that it is currently the more affordable of the two stocks. Company Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio Edesa Biotech N/A N/A -$7.19M -$1.69 N/A Tenaya Therapeutics N/A N/A -$90.60M -$0.53 N/A

Is EDSA or TNYA more profitable?

Tenaya Therapeutics' return on equity of -83.75% beat Edesa Biotech's return on equity. Company Net Margins Return on Equity Return on Assets Edesa Biotech N/A -560.22% -105.74% Tenaya Therapeutics N/A -83.75% -66.53%

Edesa Biotech (EDSA) Competitors

$3.86 -0.15 (-3.74%)

Closing price 10/2/2026 04:00 PM Eastern

Extended Trading

$3.86 0.00 (-0.05%)

As of 10/2/2026 07:56 PM Eastern

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EDSA vs. RNA, BNR, SPRB, CLLS, and TNYA

Should you buy Edesa Biotech stock or one of its competitors? Edesa Biotech's main competitors and comparable companies include Avidity Biosciences (RNA), Burning Rock Biotech (BNR), Spruce Biosciences (SPRB), Cellectis (CLLS), and Tenaya Therapeutics (TNYA). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Edesa Biotech compare to Avidity Biosciences?

Edesa Biotech (NASDAQ:EDSA) and Avidity Biosciences (NASDAQ:RNA) are both small-cap healthcare companies, but which is the better business? We will contrast the two businesses based on the strength of their institutional ownership, valuation, analyst recommendations, profitability, media sentiment, dividends, earnings and risk.

5.5% of Edesa Biotech shares are owned by institutional investors. 24.4% of Edesa Biotech shares are owned by insiders. Comparatively, 3.8% of Avidity Biosciences shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

In the previous week, Avidity Biosciences had 1 more articles in the media than Edesa Biotech. MarketBeat recorded 1 mentions for Avidity Biosciences and 0 mentions for Edesa Biotech. Avidity Biosciences' average media sentiment score of 1.11 beat Edesa Biotech's score of 0.00 indicating that Avidity Biosciences is being referred to more favorably in the news media.

Company	Overall Sentiment
Edesa Biotech	Neutral
Avidity Biosciences	Positive

Avidity Biosciences is trading at a lower price-to-earnings ratio than Edesa Biotech, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Edesa Biotech	N/A	N/A	-$7.19M	-$1.69	N/A
Avidity Biosciences	N/A	N/A	N/A	-$2.15	N/A

Edesa Biotech presently has a consensus price target of $5.00, suggesting a potential upside of 29.53%. Avidity Biosciences has a consensus price target of $63.75, suggesting a potential upside of 713.14%. Given Avidity Biosciences' higher possible upside, analysts clearly believe Avidity Biosciences is more favorable than Edesa Biotech.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Edesa Biotech	1 Sell rating(s)	0 Hold rating(s)	1 Buy rating(s)	1 Strong Buy rating(s)	2.67
Avidity Biosciences	1 Sell rating(s)	11 Hold rating(s)	3 Buy rating(s)	1 Strong Buy rating(s)	2.25

Avidity Biosciences' return on equity of 0.00% beat Edesa Biotech's return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Edesa Biotech	N/A	-560.22%	-105.74%
Avidity Biosciences	N/A	N/A	N/A

Summary

Avidity Biosciences beats Edesa Biotech on 6 of the 11 factors compared between the two stocks.

How does Edesa Biotech compare to Burning Rock Biotech?

Edesa Biotech (NASDAQ:EDSA) and Burning Rock Biotech (NASDAQ:BNR) are both small-cap healthcare companies, but which is the better business? We will compare the two companies based on the strength of their analyst recommendations, institutional ownership, valuation, earnings, risk, media sentiment, dividends and profitability.

5.5% of Edesa Biotech shares are owned by institutional investors. Comparatively, 30.0% of Burning Rock Biotech shares are owned by institutional investors. 24.4% of Edesa Biotech shares are owned by company insiders. Comparatively, 30.3% of Burning Rock Biotech shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

Edesa Biotech currently has a consensus target price of $5.00, suggesting a potential upside of 29.53%. Given Edesa Biotech's stronger consensus rating and higher probable upside, equities research analysts plainly believe Edesa Biotech is more favorable than Burning Rock Biotech.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Edesa Biotech	1 Sell rating(s)	0 Hold rating(s)	1 Buy rating(s)	1 Strong Buy rating(s)	2.67
Burning Rock Biotech	1 Sell rating(s)	0 Hold rating(s)	0 Buy rating(s)	0 Strong Buy rating(s)	1.00

In the previous week, Burning Rock Biotech had 1 more articles in the media than Edesa Biotech. MarketBeat recorded 1 mentions for Burning Rock Biotech and 0 mentions for Edesa Biotech. Edesa Biotech's average media sentiment score of 0.00 equaled Burning Rock Biotech'saverage media sentiment score.

Company	Overall Sentiment
Edesa Biotech	Neutral
Burning Rock Biotech	Neutral

Edesa Biotech has a beta of 1.2, suggesting that its stock price is 20% more volatile than the broader market. Comparatively, Burning Rock Biotech has a beta of 1.29, suggesting that its stock price is 29% more volatile than the broader market.

Edesa Biotech has a net margin of 0.00% compared to Burning Rock Biotech's net margin of -13.60%. Burning Rock Biotech's return on equity of -12.98% beat Edesa Biotech's return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Edesa Biotech	N/A	-560.22%	-105.74%
Burning Rock Biotech	-13.60%	-12.98%	-8.59%

Edesa Biotech has higher earnings, but lower revenue than Burning Rock Biotech. Burning Rock Biotech is trading at a lower price-to-earnings ratio than Edesa Biotech, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Edesa Biotech	N/A	N/A	-$7.19M	-$1.69	N/A
Burning Rock Biotech	$77.16M	2.22	-$7.92M	-$0.87	N/A

Summary

Burning Rock Biotech beats Edesa Biotech on 8 of the 15 factors compared between the two stocks.

How does Edesa Biotech compare to Spruce Biosciences?

Edesa Biotech (NASDAQ:EDSA) and Spruce Biosciences (NASDAQ:SPRB) are both small-cap healthcare companies, but which is the superior business? We will contrast the two businesses based on the strength of their analyst recommendations, profitability, risk, institutional ownership, valuation, dividends, media sentiment and earnings.

Edesa Biotech currently has a consensus price target of $5.00, suggesting a potential upside of 29.53%. Spruce Biosciences has a consensus price target of $158.33, suggesting a potential upside of 246.39%. Given Spruce Biosciences' stronger consensus rating and higher probable upside, analysts plainly believe Spruce Biosciences is more favorable than Edesa Biotech.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Edesa Biotech	1 Sell rating(s)	0 Hold rating(s)	1 Buy rating(s)	1 Strong Buy rating(s)	2.67
Spruce Biosciences	1 Sell rating(s)	1 Hold rating(s)	11 Buy rating(s)	0 Strong Buy rating(s)	2.77

5.5% of Edesa Biotech shares are held by institutional investors. Comparatively, 91.7% of Spruce Biosciences shares are held by institutional investors. 24.4% of Edesa Biotech shares are held by insiders. Comparatively, 4.3% of Spruce Biosciences shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Edesa Biotech has higher earnings, but lower revenue than Spruce Biosciences. Edesa Biotech is trading at a lower price-to-earnings ratio than Spruce Biosciences, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Edesa Biotech	N/A	N/A	-$7.19M	-$1.69	N/A
Spruce Biosciences	$4.91M	26.72	-$38.97M	-$39.78	N/A

In the previous week, Spruce Biosciences had 1 more articles in the media than Edesa Biotech. MarketBeat recorded 1 mentions for Spruce Biosciences and 0 mentions for Edesa Biotech. Edesa Biotech's average media sentiment score of 0.00 equaled Spruce Biosciences'average media sentiment score.

Company	Overall Sentiment
Edesa Biotech	Neutral
Spruce Biosciences	Neutral

Edesa Biotech has a beta of 1.2, meaning that its share price is 20% more volatile than the broader market. Comparatively, Spruce Biosciences has a beta of 3.25, meaning that its share price is 225% more volatile than the broader market.

Spruce Biosciences' return on equity of -123.53% beat Edesa Biotech's return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Edesa Biotech	N/A	-560.22%	-105.74%
Spruce Biosciences	N/A	-123.53%	-90.35%

Summary

Spruce Biosciences beats Edesa Biotech on 10 of the 14 factors compared between the two stocks.

How does Edesa Biotech compare to Cellectis?

Edesa Biotech (NASDAQ:EDSA) and Cellectis (NASDAQ:CLLS) are both small-cap healthcare companies, but which is the better investment? We will contrast the two companies based on the strength of their valuation, media sentiment, analyst recommendations, institutional ownership, risk, dividends, earnings and profitability.

Edesa Biotech has a net margin of 0.00% compared to Cellectis' net margin of -102.34%. Cellectis' return on equity of -94.19% beat Edesa Biotech's return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Edesa Biotech	N/A	-560.22%	-105.74%
Cellectis	-102.34%	-94.19%	-21.34%

Edesa Biotech has higher earnings, but lower revenue than Cellectis. Edesa Biotech is trading at a lower price-to-earnings ratio than Cellectis, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Edesa Biotech	N/A	N/A	-$7.19M	-$1.69	N/A
Cellectis	$79.59M	1.80	-$67.59M	-$0.65	N/A

Edesa Biotech has a beta of 1.2, meaning that its stock price is 20% more volatile than the broader market. Comparatively, Cellectis has a beta of 3, meaning that its stock price is 200% more volatile than the broader market.

Edesa Biotech presently has a consensus price target of $5.00, suggesting a potential upside of 29.53%. Cellectis has a consensus price target of $5.46, suggesting a potential upside of 281.82%. Given Cellectis' higher probable upside, analysts plainly believe Cellectis is more favorable than Edesa Biotech.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Edesa Biotech	1 Sell rating(s)	0 Hold rating(s)	1 Buy rating(s)	1 Strong Buy rating(s)	2.67
Cellectis	2 Sell rating(s)	2 Hold rating(s)	2 Buy rating(s)	1 Strong Buy rating(s)	2.29

5.5% of Edesa Biotech shares are owned by institutional investors. Comparatively, 63.9% of Cellectis shares are owned by institutional investors. 24.4% of Edesa Biotech shares are owned by company insiders. Comparatively, 16.4% of Cellectis shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

In the previous week, Cellectis had 7 more articles in the media than Edesa Biotech. MarketBeat recorded 7 mentions for Cellectis and 0 mentions for Edesa Biotech. Cellectis' average media sentiment score of 0.24 beat Edesa Biotech's score of 0.00 indicating that Cellectis is being referred to more favorably in the news media.

Company	Overall Sentiment
Edesa Biotech	Neutral
Cellectis	Neutral

Summary

Cellectis beats Edesa Biotech on 11 of the 15 factors compared between the two stocks.

How does Edesa Biotech compare to Tenaya Therapeutics?

Edesa Biotech (NASDAQ:EDSA) and Tenaya Therapeutics (NASDAQ:TNYA) are both small-cap healthcare companies, but which is the better investment? We will compare the two businesses based on the strength of their earnings, analyst recommendations, valuation, institutional ownership, media sentiment, dividends, risk and profitability.

In the previous week, Tenaya Therapeutics had 3 more articles in the media than Edesa Biotech. MarketBeat recorded 3 mentions for Tenaya Therapeutics and 0 mentions for Edesa Biotech. Tenaya Therapeutics' average media sentiment score of 0.34 beat Edesa Biotech's score of 0.00 indicating that Tenaya Therapeutics is being referred to more favorably in the news media.

Company	Overall Sentiment
Edesa Biotech	Neutral
Tenaya Therapeutics	Neutral

Edesa Biotech is trading at a lower price-to-earnings ratio than Tenaya Therapeutics, indicating that it is currently the more affordable of the two stocks.

Company	Gross Revenue	Price/Sales Ratio	Net Income	Earnings Per Share	Price/Earnings Ratio
Edesa Biotech	N/A	N/A	-$7.19M	-$1.69	N/A
Tenaya Therapeutics	N/A	N/A	-$90.60M	-$0.53	N/A

Edesa Biotech currently has a consensus target price of $5.00, suggesting a potential upside of 29.53%. Tenaya Therapeutics has a consensus target price of $4.00, suggesting a potential upside of 609.09%. Given Tenaya Therapeutics' stronger consensus rating and higher probable upside, analysts plainly believe Tenaya Therapeutics is more favorable than Edesa Biotech.

Company	Sell Ratings	Hold Ratings	Buy Ratings	Strong Buy Ratings	Rating Score
Edesa Biotech	1 Sell rating(s)	0 Hold rating(s)	1 Buy rating(s)	1 Strong Buy rating(s)	2.67
Tenaya Therapeutics	1 Sell rating(s)	0 Hold rating(s)	5 Buy rating(s)	1 Strong Buy rating(s)	2.86

Edesa Biotech has a beta of 1.2, meaning that its share price is 20% more volatile than the broader market. Comparatively, Tenaya Therapeutics has a beta of 2.87, meaning that its share price is 187% more volatile than the broader market.

Tenaya Therapeutics' return on equity of -83.75% beat Edesa Biotech's return on equity.

Company	Net Margins	Return on Equity	Return on Assets
Edesa Biotech	N/A	-560.22%	-105.74%
Tenaya Therapeutics	N/A	-83.75%	-66.53%

5.5% of Edesa Biotech shares are held by institutional investors. Comparatively, 90.5% of Tenaya Therapeutics shares are held by institutional investors. 24.4% of Edesa Biotech shares are held by company insiders. Comparatively, 2.5% of Tenaya Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Summary

Tenaya Therapeutics beats Edesa Biotech on 11 of the 13 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding EDSA and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.

Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.

EDSA vs. The Competition

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Metric	Edesa Biotech	Biotechnology Industry	Healthcare Sector	NASDAQ Exchange
Market Cap	$37.21M	$3.85B	$7.15B	$13.28B
Dividend Yield	N/A	3.65%	2.54%	17.33%
P/E Ratio	-2.28	13.00	274.71	26.04
Price / Sales	N/A	1,288.64	656.46	105.13
Price / Cash	N/A	123.39	78.87	52.62
Price / Book	8.58	16.57	10.93	6.31
Net Income	-$7.19M	-$22.66M	$3.51B	$362.16M
7 Day Performance	-3.74%	-2.97%	-2.00%	-1.66%
1 Month Performance	-18.39%	-10.82%	-6.19%	-4.68%
1 Year Performance	50.78%	19.00%	8.03%	1.57%

Edesa Biotech Competitors List

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Company	MarketRank	Share Price	Analysts' Price Target	1Y Price Performance	Market Cap	Revenue	P/E Ratio	Employee Count	Indicator(s)
EDSA Edesa Biotech	1.8428 of 5 stars	$3.86 -3.7%	$5.00 +29.5%	+50.8%	$37.21M	N/A	N/A	17
RNA Avidity Biosciences	1.7294 of 5 stars	$9.22 +0.3%	$63.75 +591.4%	-83.3%	$157.20M	N/A	N/A	190	Positive News
BNR Burning Rock Biotech	0.2459 of 5 stars	$16.45 +11.7%	N/A	+77.8%	$154.93M	$77.16M	N/A	667	Gap Up
SPRB Spruce Biosciences	3.1932 of 5 stars	$49.99 -6.9%	$158.33 +216.7%	+475.0%	$154.34M	$4.91M	N/A	8	Gap Up
CLLS Cellectis	3.229 of 5 stars	$1.56 +3.3%	$5.46 +250.0%	-59.1%	$151.51M	$79.59M	N/A	229	Analyst Upgrade Short Interest Increase Gap Up

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This page (NASDAQ:EDSA) was last updated on 10/4/2026 by MarketBeat.com Staff.

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Edesa Biotech (EDSA) Competitors

EDSA vs. RNA, BNR, SPRB, CLLS, and TNYA

How does Edesa Biotech compare to Avidity Biosciences?

Summary

How does Edesa Biotech compare to Burning Rock Biotech?

Summary

How does Edesa Biotech compare to Spruce Biosciences?

Summary

How does Edesa Biotech compare to Cellectis?

Summary

How does Edesa Biotech compare to Tenaya Therapeutics?

Summary

New MarketBeat Followers Over Time

Media Sentiment Over Time

EDSA vs. The Competition

Edesa Biotech Competitors List

Related Companies and Tools

Best-in-Class Portfolio Monitoring

Stock Ideas and Recommendations

Advanced Stock Screeners and Research Tools

About MarketBeat

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Edesa Biotech (EDSA) Competitors

EDSA vs. RNA, BNR, SPRB, CLLS, and TNYA

How does Edesa Biotech compare to Avidity Biosciences?

Do institutionals and insiders hold more shares of EDSA or RNA?

Does the media favor EDSA or RNA?

Which has stronger earnings and valuation, EDSA or RNA?

Do analysts rate EDSA or RNA?

Is EDSA or RNA more profitable?

Summary

How does Edesa Biotech compare to Burning Rock Biotech?

Do insiders and institutionals have more ownership in EDSA or BNR?

Do analysts prefer EDSA or BNR?

Does the media favor EDSA or BNR?

Which has more risk and volatility, EDSA or BNR?

Is EDSA or BNR more profitable?

Which has better valuation & earnings, EDSA or BNR?

Summary

How does Edesa Biotech compare to Spruce Biosciences?

Do analysts rate EDSA or SPRB?

Do insiders & institutionals have more ownership in EDSA or SPRB?

Which has better earnings & valuation, EDSA or SPRB?

Does the media prefer EDSA or SPRB?

Which has more volatility & risk, EDSA or SPRB?

Is EDSA or SPRB more profitable?

Summary

How does Edesa Biotech compare to Cellectis?

Is EDSA or CLLS more profitable?

Which has stronger valuation & earnings, EDSA or CLLS?

Which has more risk and volatility, EDSA or CLLS?

Do analysts prefer EDSA or CLLS?

Do institutionals & insiders hold more shares of EDSA or CLLS?

Does the media refer more to EDSA or CLLS?

Summary

How does Edesa Biotech compare to Tenaya Therapeutics?

Does the media favor EDSA or TNYA?

Which has stronger valuation and earnings, EDSA or TNYA?

Do analysts recommend EDSA or TNYA?

Which has more volatility & risk, EDSA or TNYA?

Is EDSA or TNYA more profitable?

Do institutionals and insiders have more ownership in EDSA or TNYA?

Summary

New MarketBeat Followers Over Time

Media Sentiment Over Time

EDSA vs. The Competition

Edesa Biotech Competitors List

Related Companies and Tools

MarketBeat All Access Features

Best-in-Class Portfolio Monitoring

Stock Ideas and Recommendations

Advanced Stock Screeners and Research Tools