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Fulcrum Therapeutics (FULC) Competitors

Fulcrum Therapeutics logo
$6.88 +0.36 (+5.52%)
Closing price 08/22/2025 04:00 PM Eastern
Extended Trading
$6.88 +0.00 (+0.01%)
As of 08/22/2025 05:10 PM Eastern
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FULC vs. ARDX, HROW, SPRY, SDGR, AMPH, VERA, ABCL, ETNB, SNDX, and COGT

Should you be buying Fulcrum Therapeutics stock or one of its competitors? The main competitors of Fulcrum Therapeutics include Ardelyx (ARDX), Harrow (HROW), ARS Pharmaceuticals (SPRY), Schrodinger (SDGR), Amphastar Pharmaceuticals (AMPH), Vera Therapeutics (VERA), AbCellera Biologics (ABCL), 89BIO (ETNB), Syndax Pharmaceuticals (SNDX), and Cogent Biosciences (COGT). These companies are all part of the "pharmaceutical products" industry.

Fulcrum Therapeutics vs. Its Competitors

Ardelyx (NASDAQ:ARDX) and Fulcrum Therapeutics (NASDAQ:FULC) are both small-cap medical companies, but which is the superior stock? We will contrast the two companies based on the strength of their profitability, dividends, earnings, risk, media sentiment, valuation, analyst recommendations and institutional ownership.

In the previous week, Ardelyx had 2 more articles in the media than Fulcrum Therapeutics. MarketBeat recorded 4 mentions for Ardelyx and 2 mentions for Fulcrum Therapeutics. Ardelyx's average media sentiment score of 1.32 beat Fulcrum Therapeutics' score of 1.15 indicating that Ardelyx is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Ardelyx
3 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Fulcrum Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Fulcrum Therapeutics has a net margin of 0.00% compared to Ardelyx's net margin of -14.60%. Fulcrum Therapeutics' return on equity of -31.05% beat Ardelyx's return on equity.

Company Net Margins Return on Equity Return on Assets
Ardelyx-14.60% -36.57% -13.42%
Fulcrum Therapeutics N/A -31.05%-28.96%

58.9% of Ardelyx shares are held by institutional investors. Comparatively, 89.8% of Fulcrum Therapeutics shares are held by institutional investors. 4.8% of Ardelyx shares are held by insiders. Comparatively, 7.0% of Fulcrum Therapeutics shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Fulcrum Therapeutics has lower revenue, but higher earnings than Ardelyx. Ardelyx is trading at a lower price-to-earnings ratio than Fulcrum Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Ardelyx$333.61M4.41-$39.14M-$0.23-26.57
Fulcrum TherapeuticsN/AN/A-$9.73M-$1.22-5.64

Ardelyx has a beta of 0.68, meaning that its stock price is 32% less volatile than the S&P 500. Comparatively, Fulcrum Therapeutics has a beta of 2.47, meaning that its stock price is 147% more volatile than the S&P 500.

Ardelyx currently has a consensus price target of $11.50, indicating a potential upside of 88.22%. Fulcrum Therapeutics has a consensus price target of $7.57, indicating a potential upside of 10.05%. Given Ardelyx's stronger consensus rating and higher possible upside, equities research analysts plainly believe Ardelyx is more favorable than Fulcrum Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Ardelyx
0 Sell rating(s)
1 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
3.00
Fulcrum Therapeutics
1 Sell rating(s)
2 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.63

Summary

Ardelyx beats Fulcrum Therapeutics on 8 of the 15 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding FULC and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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FULC vs. The Competition

MetricFulcrum TherapeuticsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$352.68M$3.11B$5.76B$9.58B
Dividend YieldN/A2.23%4.41%4.10%
P/E Ratio-5.6420.8831.1026.04
Price / SalesN/A348.74435.03103.40
Price / CashN/A43.1937.7358.48
Price / Book1.748.129.536.61
Net Income-$9.73M-$54.72M$3.26B$265.56M
7 Day Performance0.88%2.63%2.10%1.97%
1 Month Performance-13.02%2.78%2.82%-0.36%
1 Year Performance-24.97%11.01%30.56%19.03%

Fulcrum Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
FULC
Fulcrum Therapeutics
0.9836 of 5 stars
$6.88
+5.5%
$7.57
+10.0%
-21.7%$352.68MN/A-5.64100
ARDX
Ardelyx
4.3303 of 5 stars
$5.81
-2.7%
$11.50
+97.9%
+1.0%$1.44B$386.15M-25.2690
HROW
Harrow
3.6473 of 5 stars
$38.32
-1.3%
$64.67
+68.8%
-5.3%$1.44B$199.61M-153.28180Analyst Revision
SPRY
ARS Pharmaceuticals
2.455 of 5 stars
$14.03
-3.4%
$31.00
+121.0%
+5.4%$1.44B$89.15M-28.6390Insider Trade
SDGR
Schrodinger
3.1095 of 5 stars
$20.05
+3.5%
$27.83
+38.8%
+4.3%$1.43B$207.54M-8.08790
AMPH
Amphastar Pharmaceuticals
3.4489 of 5 stars
$29.76
-0.2%
$31.50
+5.8%
-35.4%$1.39B$731.97M11.152,028Positive News
VERA
Vera Therapeutics
3.7509 of 5 stars
$21.80
+1.2%
$63.00
+189.0%
-42.3%$1.37BN/A-6.0940Positive News
ABCL
AbCellera Biologics
2.2936 of 5 stars
$4.67
+1.7%
$8.00
+71.3%
+74.9%$1.37B$28.83M-8.49500Gap Up
ETNB
89BIO
2.0198 of 5 stars
$9.44
+2.3%
$26.29
+178.5%
+11.3%$1.37BN/A-2.6140
SNDX
Syndax Pharmaceuticals
4.0835 of 5 stars
$15.87
+0.8%
$38.00
+139.4%
-20.1%$1.36B$77.93M-4.08110
COGT
Cogent Biosciences
3.6326 of 5 stars
$12.11
+1.9%
$18.70
+54.4%
+24.7%$1.35BN/A-6.8080Positive News

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This page (NASDAQ:FULC) was last updated on 8/23/2025 by MarketBeat.com Staff
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