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Lexicon Pharmaceuticals (LXRX) Competitors

Lexicon Pharmaceuticals logo
$2.00 +0.32 (+19.05%)
Closing price 04:00 PM Eastern
Extended Trading
$1.89 -0.11 (-5.50%)
As of 06:09 PM Eastern
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LXRX vs. BCRX, CLDX, INVA, NVAX, and ZBIO

Should you be buying Lexicon Pharmaceuticals stock or one of its competitors? The main competitors of Lexicon Pharmaceuticals include BioCryst Pharmaceuticals (BCRX), Celldex Therapeutics (CLDX), Innoviva (INVA), Novavax (NVAX), and Zenas BioPharma (ZBIO). These companies are all part of the "biotechnology" industry.

How does Lexicon Pharmaceuticals compare to BioCryst Pharmaceuticals?

Lexicon Pharmaceuticals (NASDAQ:LXRX) and BioCryst Pharmaceuticals (NASDAQ:BCRX) are both medical companies, but which is the superior investment? We will compare the two businesses based on the strength of their media sentiment, valuation, risk, analyst recommendations, dividends, earnings, profitability and institutional ownership.

BioCryst Pharmaceuticals has higher revenue and earnings than Lexicon Pharmaceuticals. Lexicon Pharmaceuticals is trading at a lower price-to-earnings ratio than BioCryst Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Lexicon Pharmaceuticals$49.80M17.02-$50.34M-$0.14N/A
BioCryst Pharmaceuticals$885.72M2.47$263.86M-$1.78N/A

In the previous week, BioCryst Pharmaceuticals had 12 more articles in the media than Lexicon Pharmaceuticals. MarketBeat recorded 23 mentions for BioCryst Pharmaceuticals and 11 mentions for Lexicon Pharmaceuticals. Lexicon Pharmaceuticals' average media sentiment score of 0.47 beat BioCryst Pharmaceuticals' score of 0.12 indicating that Lexicon Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Lexicon Pharmaceuticals
0 Very Positive mention(s)
4 Positive mention(s)
6 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
BioCryst Pharmaceuticals
5 Very Positive mention(s)
2 Positive mention(s)
9 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral

Lexicon Pharmaceuticals has a beta of 0.97, meaning that its share price is 3% less volatile than the S&P 500. Comparatively, BioCryst Pharmaceuticals has a beta of 0.57, meaning that its share price is 43% less volatile than the S&P 500.

BioCryst Pharmaceuticals has a net margin of -51.71% compared to Lexicon Pharmaceuticals' net margin of -101.08%. Lexicon Pharmaceuticals' return on equity of -41.94% beat BioCryst Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Lexicon Pharmaceuticals-101.08% -41.94% -22.03%
BioCryst Pharmaceuticals -51.71%-91.42%59.88%

74.7% of Lexicon Pharmaceuticals shares are held by institutional investors. Comparatively, 85.9% of BioCryst Pharmaceuticals shares are held by institutional investors. 14.0% of Lexicon Pharmaceuticals shares are held by insiders. Comparatively, 5.1% of BioCryst Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

Lexicon Pharmaceuticals currently has a consensus price target of $4.15, suggesting a potential upside of 107.50%. BioCryst Pharmaceuticals has a consensus price target of $20.70, suggesting a potential upside of 140.14%. Given BioCryst Pharmaceuticals' stronger consensus rating and higher probable upside, analysts plainly believe BioCryst Pharmaceuticals is more favorable than Lexicon Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Lexicon Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33
BioCryst Pharmaceuticals
0 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.75

Summary

BioCryst Pharmaceuticals beats Lexicon Pharmaceuticals on 10 of the 16 factors compared between the two stocks.

How does Lexicon Pharmaceuticals compare to Celldex Therapeutics?

Lexicon Pharmaceuticals (NASDAQ:LXRX) and Celldex Therapeutics (NASDAQ:CLDX) are both medical companies, but which is the better business? We will compare the two companies based on the strength of their analyst recommendations, institutional ownership, risk, media sentiment, profitability, valuation, dividends and earnings.

Lexicon Pharmaceuticals has a beta of 0.97, suggesting that its stock price is 3% less volatile than the S&P 500. Comparatively, Celldex Therapeutics has a beta of 0.98, suggesting that its stock price is 2% less volatile than the S&P 500.

74.7% of Lexicon Pharmaceuticals shares are owned by institutional investors. 14.0% of Lexicon Pharmaceuticals shares are owned by insiders. Comparatively, 4.4% of Celldex Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Lexicon Pharmaceuticals presently has a consensus target price of $4.15, indicating a potential upside of 107.50%. Celldex Therapeutics has a consensus target price of $46.64, indicating a potential upside of 37.29%. Given Lexicon Pharmaceuticals' higher probable upside, analysts plainly believe Lexicon Pharmaceuticals is more favorable than Celldex Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Lexicon Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33
Celldex Therapeutics
1 Sell rating(s)
1 Hold rating(s)
9 Buy rating(s)
1 Strong Buy rating(s)
2.83

In the previous week, Lexicon Pharmaceuticals had 4 more articles in the media than Celldex Therapeutics. MarketBeat recorded 11 mentions for Lexicon Pharmaceuticals and 7 mentions for Celldex Therapeutics. Lexicon Pharmaceuticals' average media sentiment score of 0.47 beat Celldex Therapeutics' score of -0.26 indicating that Lexicon Pharmaceuticals is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Lexicon Pharmaceuticals
0 Very Positive mention(s)
4 Positive mention(s)
6 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Celldex Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral

Lexicon Pharmaceuticals has higher revenue and earnings than Celldex Therapeutics. Lexicon Pharmaceuticals is trading at a lower price-to-earnings ratio than Celldex Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Lexicon Pharmaceuticals$49.80M17.02-$50.34M-$0.14N/A
Celldex Therapeutics$1.55M1,725.81-$258.76M-$4.26N/A

Celldex Therapeutics has a net margin of 0.00% compared to Lexicon Pharmaceuticals' net margin of -101.08%. Celldex Therapeutics' return on equity of -41.67% beat Lexicon Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Lexicon Pharmaceuticals-101.08% -41.94% -22.03%
Celldex Therapeutics N/A -41.67%-38.86%

Summary

Lexicon Pharmaceuticals beats Celldex Therapeutics on 9 of the 17 factors compared between the two stocks.

How does Lexicon Pharmaceuticals compare to Innoviva?

Lexicon Pharmaceuticals (NASDAQ:LXRX) and Innoviva (NASDAQ:INVA) are both small-cap medical companies, but which is the better business? We will contrast the two companies based on the strength of their risk, analyst recommendations, institutional ownership, valuation, profitability, media sentiment, earnings and dividends.

Lexicon Pharmaceuticals has a beta of 0.97, suggesting that its share price is 3% less volatile than the S&P 500. Comparatively, Innoviva has a beta of 0.38, suggesting that its share price is 62% less volatile than the S&P 500.

Innoviva has higher revenue and earnings than Lexicon Pharmaceuticals. Lexicon Pharmaceuticals is trading at a lower price-to-earnings ratio than Innoviva, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Lexicon Pharmaceuticals$49.80M17.02-$50.34M-$0.14N/A
Innoviva$420.69M4.03$271.17M$6.013.81

Innoviva has a net margin of 119.89% compared to Lexicon Pharmaceuticals' net margin of -101.08%. Innoviva's return on equity of 36.58% beat Lexicon Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Lexicon Pharmaceuticals-101.08% -41.94% -22.03%
Innoviva 119.89%36.58%24.10%

74.7% of Lexicon Pharmaceuticals shares are owned by institutional investors. Comparatively, 99.1% of Innoviva shares are owned by institutional investors. 14.0% of Lexicon Pharmaceuticals shares are owned by company insiders. Comparatively, 2.0% of Innoviva shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

Lexicon Pharmaceuticals presently has a consensus target price of $4.15, suggesting a potential upside of 107.50%. Innoviva has a consensus target price of $36.20, suggesting a potential upside of 58.15%. Given Lexicon Pharmaceuticals' higher probable upside, equities research analysts plainly believe Lexicon Pharmaceuticals is more favorable than Innoviva.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Lexicon Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33
Innoviva
1 Sell rating(s)
1 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.57

In the previous week, Lexicon Pharmaceuticals had 3 more articles in the media than Innoviva. MarketBeat recorded 11 mentions for Lexicon Pharmaceuticals and 8 mentions for Innoviva. Innoviva's average media sentiment score of 1.36 beat Lexicon Pharmaceuticals' score of 0.47 indicating that Innoviva is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Lexicon Pharmaceuticals
0 Very Positive mention(s)
4 Positive mention(s)
6 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Innoviva
4 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Innoviva beats Lexicon Pharmaceuticals on 11 of the 16 factors compared between the two stocks.

How does Lexicon Pharmaceuticals compare to Novavax?

Lexicon Pharmaceuticals (NASDAQ:LXRX) and Novavax (NASDAQ:NVAX) are both small-cap medical companies, but which is the better business? We will contrast the two companies based on the strength of their risk, analyst recommendations, institutional ownership, valuation, profitability, media sentiment, earnings and dividends.

Lexicon Pharmaceuticals has a beta of 0.97, suggesting that its share price is 3% less volatile than the S&P 500. Comparatively, Novavax has a beta of 2.37, suggesting that its share price is 137% more volatile than the S&P 500.

Novavax has higher revenue and earnings than Lexicon Pharmaceuticals. Lexicon Pharmaceuticals is trading at a lower price-to-earnings ratio than Novavax, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Lexicon Pharmaceuticals$49.80M17.02-$50.34M-$0.14N/A
Novavax$1.12B1.48$440.30M$2.414.20

Novavax has a net margin of -14.73% compared to Lexicon Pharmaceuticals' net margin of -101.08%. Novavax's return on equity of -17.64% beat Lexicon Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Lexicon Pharmaceuticals-101.08% -41.94% -22.03%
Novavax -14.73%-17.64%1.18%

74.7% of Lexicon Pharmaceuticals shares are owned by institutional investors. Comparatively, 53.0% of Novavax shares are owned by institutional investors. 14.0% of Lexicon Pharmaceuticals shares are owned by company insiders. Comparatively, 1.0% of Novavax shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

Lexicon Pharmaceuticals presently has a consensus target price of $4.15, suggesting a potential upside of 107.50%. Novavax has a consensus target price of $12.13, suggesting a potential upside of 19.93%. Given Lexicon Pharmaceuticals' stronger consensus rating and higher probable upside, equities research analysts plainly believe Lexicon Pharmaceuticals is more favorable than Novavax.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Lexicon Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33
Novavax
4 Sell rating(s)
1 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.10

In the previous week, Novavax had 22 more articles in the media than Lexicon Pharmaceuticals. MarketBeat recorded 33 mentions for Novavax and 11 mentions for Lexicon Pharmaceuticals. Novavax's average media sentiment score of 0.65 beat Lexicon Pharmaceuticals' score of 0.47 indicating that Novavax is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Lexicon Pharmaceuticals
0 Very Positive mention(s)
4 Positive mention(s)
6 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Novavax
12 Very Positive mention(s)
6 Positive mention(s)
10 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Novavax beats Lexicon Pharmaceuticals on 10 of the 16 factors compared between the two stocks.

How does Lexicon Pharmaceuticals compare to Zenas BioPharma?

Zenas BioPharma (NASDAQ:ZBIO) and Lexicon Pharmaceuticals (NASDAQ:LXRX) are both small-cap medical companies, but which is the superior investment? We will contrast the two businesses based on the strength of their risk, analyst recommendations, earnings, dividends, media sentiment, valuation, profitability and institutional ownership.

Lexicon Pharmaceuticals has higher revenue and earnings than Zenas BioPharma. Lexicon Pharmaceuticals is trading at a lower price-to-earnings ratio than Zenas BioPharma, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Zenas BioPharma$10M112.68-$377.74M-$7.81N/A
Lexicon Pharmaceuticals$49.80M17.02-$50.34M-$0.14N/A

Zenas BioPharma has a net margin of 0.00% compared to Lexicon Pharmaceuticals' net margin of -101.08%. Lexicon Pharmaceuticals' return on equity of -41.94% beat Zenas BioPharma's return on equity.

Company Net Margins Return on Equity Return on Assets
Zenas BioPharmaN/A -85.64% -61.86%
Lexicon Pharmaceuticals -101.08%-41.94%-22.03%

Zenas BioPharma currently has a consensus target price of $44.14, suggesting a potential upside of 124.76%. Lexicon Pharmaceuticals has a consensus target price of $4.15, suggesting a potential upside of 107.50%. Given Zenas BioPharma's stronger consensus rating and higher possible upside, analysts plainly believe Zenas BioPharma is more favorable than Lexicon Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Zenas BioPharma
2 Sell rating(s)
1 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.44
Lexicon Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33

Zenas BioPharma has a beta of -0.61, suggesting that its stock price is 161% less volatile than the S&P 500. Comparatively, Lexicon Pharmaceuticals has a beta of 0.97, suggesting that its stock price is 3% less volatile than the S&P 500.

74.7% of Lexicon Pharmaceuticals shares are held by institutional investors. 22.0% of Zenas BioPharma shares are held by insiders. Comparatively, 14.0% of Lexicon Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.

In the previous week, Lexicon Pharmaceuticals had 8 more articles in the media than Zenas BioPharma. MarketBeat recorded 11 mentions for Lexicon Pharmaceuticals and 3 mentions for Zenas BioPharma. Lexicon Pharmaceuticals' average media sentiment score of 0.47 beat Zenas BioPharma's score of 0.42 indicating that Lexicon Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Zenas BioPharma
0 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Lexicon Pharmaceuticals
0 Very Positive mention(s)
4 Positive mention(s)
6 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Summary

Lexicon Pharmaceuticals beats Zenas BioPharma on 9 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding LXRX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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LXRX vs. The Competition

MetricLexicon PharmaceuticalsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$847.36M$3.37B$6.18B$12.29B
Dividend YieldN/A2.22%2.78%5.24%
P/E Ratio-14.2835.0728.7327.27
Price / Sales17.02187.69507.2964.11
Price / CashN/A125.2843.3053.97
Price / Book6.677.3510.006.83
Net Income-$50.34M$23.67M$3.54B$332.87M
7 Day PerformanceN/AN/AN/A0.09%
1 Month Performance19.76%5.27%4.66%7.36%
1 Year Performance193.26%76.22%40.41%41.09%

Lexicon Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
LXRX
Lexicon Pharmaceuticals
2.3612 of 5 stars
$2.00
+19.0%
$4.15
+107.5%
+148.5%$847.36M$49.80MN/A140
BCRX
BioCryst Pharmaceuticals
3.6785 of 5 stars
$9.20
+0.1%
$19.64
+113.4%
-11.7%$2.34B$874.84M7.67530
CLDX
Celldex Therapeutics
2.3404 of 5 stars
$32.77
+1.4%
$46.36
+41.5%
+76.2%$2.15B$1.54MN/A150
INVA
Innoviva
3.85 of 5 stars
$22.99
-0.5%
$34.80
+51.4%
+21.7%$1.71B$411.33M7.54100
NVAX
Novavax
1.734 of 5 stars
$8.03
-0.1%
$11.88
+47.9%
+55.1%$1.32B$1.12B3.331,990

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This page (NASDAQ:LXRX) was last updated on 5/8/2026 by MarketBeat.com Staff.
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