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Phio Pharmaceuticals (PHIO) Competitors

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$1.11 -0.02 (-1.77%)
As of 09/3/2026 04:00 PM Eastern

PHIO vs. APLM, ATYR, ALPS, TIL, and TCRX

Should you buy Phio Pharmaceuticals stock or one of its competitors? Phio Pharmaceuticals's main competitors and comparable companies include Apollomics (APLM), aTyr Pharma (ATYR), ALPS Group Inc Ordinary Share (ALPS), Instil Bio (TIL), and TScan Therapeutics (TCRX). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Phio Pharmaceuticals compare to Apollomics?

Phio Pharmaceuticals (NASDAQ:PHIO) and Apollomics (NASDAQ:APLM) are both small-cap healthcare companies, but which is the better stock? We will contrast the two companies based on the strength of their valuation, analyst recommendations, risk, earnings, media sentiment, institutional ownership, profitability and dividends.

Phio Pharmaceuticals has a beta of 0.8, meaning that its stock price is 20% less volatile than the broader market. Comparatively, Apollomics has a beta of 1.53, meaning that its stock price is 53% more volatile than the broader market.

57.3% of Phio Pharmaceuticals shares are held by institutional investors. Comparatively, 19.1% of Apollomics shares are held by institutional investors. 3.5% of Phio Pharmaceuticals shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

Apollomics' return on equity of 0.00% beat Phio Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Phio PharmaceuticalsN/A -87.41% -79.76%
Apollomics N/A N/A N/A

Phio Pharmaceuticals has higher earnings, but lower revenue than Apollomics.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Phio PharmaceuticalsN/AN/A-$8.70M-$1.29N/A
Apollomics$8.50M7.25-$10.94MN/AN/A

In the previous week, Phio Pharmaceuticals had 5 more articles in the media than Apollomics. MarketBeat recorded 5 mentions for Phio Pharmaceuticals and 0 mentions for Apollomics. Apollomics' average media sentiment score of 0.00 beat Phio Pharmaceuticals' score of -0.80 indicating that Apollomics is being referred to more favorably in the news media.

Company Overall Sentiment
Phio Pharmaceuticals Negative
Apollomics Neutral

Phio Pharmaceuticals presently has a consensus price target of $14.00, suggesting a potential upside of 1,161.26%. Given Phio Pharmaceuticals' stronger consensus rating and higher possible upside, equities analysts clearly believe Phio Pharmaceuticals is more favorable than Apollomics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Phio Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00
Apollomics
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00

Summary

Phio Pharmaceuticals beats Apollomics on 7 of the 12 factors compared between the two stocks.

How does Phio Pharmaceuticals compare to aTyr Pharma?

aTyr Pharma (NASDAQ:ATYR) and Phio Pharmaceuticals (NASDAQ:PHIO) are both small-cap healthcare companies, but which is the superior investment? We will compare the two companies based on the strength of their risk, institutional ownership, valuation, earnings, analyst recommendations, media sentiment, dividends and profitability.

Phio Pharmaceuticals has lower revenue, but higher earnings than aTyr Pharma. Phio Pharmaceuticals is trading at a lower price-to-earnings ratio than aTyr Pharma, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
aTyr Pharma$190K259.94-$74.12M-$0.62N/A
Phio PharmaceuticalsN/AN/A-$8.70M-$1.29N/A

aTyr Pharma has a beta of 0.53, meaning that its stock price is 47% less volatile than the broader market. Comparatively, Phio Pharmaceuticals has a beta of 0.8, meaning that its stock price is 20% less volatile than the broader market.

Phio Pharmaceuticals' return on equity of -87.41% beat aTyr Pharma's return on equity.

Company Net Margins Return on Equity Return on Assets
aTyr PharmaN/A -95.89% -69.67%
Phio Pharmaceuticals N/A -87.41%-79.76%

Phio Pharmaceuticals has a consensus target price of $14.00, suggesting a potential upside of 1,161.26%. Given Phio Pharmaceuticals' higher probable upside, analysts plainly believe Phio Pharmaceuticals is more favorable than aTyr Pharma.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
aTyr Pharma
1 Sell rating(s)
5 Hold rating(s)
1 Buy rating(s)
1 Strong Buy rating(s)
2.25
Phio Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00

In the previous week, Phio Pharmaceuticals had 1 more articles in the media than aTyr Pharma. MarketBeat recorded 5 mentions for Phio Pharmaceuticals and 4 mentions for aTyr Pharma. aTyr Pharma's average media sentiment score of 0.50 beat Phio Pharmaceuticals' score of -0.80 indicating that aTyr Pharma is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
aTyr Pharma
1 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Phio Pharmaceuticals
0 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Negative

61.7% of aTyr Pharma shares are held by institutional investors. Comparatively, 57.3% of Phio Pharmaceuticals shares are held by institutional investors. 5.8% of aTyr Pharma shares are held by insiders. Comparatively, 3.5% of Phio Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

Summary

aTyr Pharma beats Phio Pharmaceuticals on 9 of the 14 factors compared between the two stocks.

How does Phio Pharmaceuticals compare to ALPS Group Inc Ordinary Share?

ALPS Group Inc Ordinary Share (NASDAQ:ALPS) and Phio Pharmaceuticals (NASDAQ:PHIO) are both small-cap healthcare companies, but which is the better investment? We will contrast the two businesses based on the strength of their profitability, earnings, analyst recommendations, valuation, institutional ownership, dividends, risk and media sentiment.

27.9% of ALPS Group Inc Ordinary Share shares are owned by institutional investors. Comparatively, 57.3% of Phio Pharmaceuticals shares are owned by institutional investors. 25.5% of ALPS Group Inc Ordinary Share shares are owned by company insiders. Comparatively, 3.5% of Phio Pharmaceuticals shares are owned by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Phio Pharmaceuticals has a consensus price target of $14.00, indicating a potential upside of 1,161.26%. Given Phio Pharmaceuticals' stronger consensus rating and higher probable upside, analysts plainly believe Phio Pharmaceuticals is more favorable than ALPS Group Inc Ordinary Share.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
ALPS Group Inc Ordinary Share
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00
Phio Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00

ALPS Group Inc Ordinary Share has a beta of -0.1, indicating that its stock price is 110% less volatile than the broader market. Comparatively, Phio Pharmaceuticals has a beta of 0.8, indicating that its stock price is 20% less volatile than the broader market.

ALPS Group Inc Ordinary Share's return on equity of 0.00% beat Phio Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
ALPS Group Inc Ordinary ShareN/A N/A N/A
Phio Pharmaceuticals N/A -87.41%-79.76%

In the previous week, Phio Pharmaceuticals had 5 more articles in the media than ALPS Group Inc Ordinary Share. MarketBeat recorded 5 mentions for Phio Pharmaceuticals and 0 mentions for ALPS Group Inc Ordinary Share. ALPS Group Inc Ordinary Share's average media sentiment score of 0.00 beat Phio Pharmaceuticals' score of -0.80 indicating that ALPS Group Inc Ordinary Share is being referred to more favorably in the media.

Company Overall Sentiment
ALPS Group Inc Ordinary Share Neutral
Phio Pharmaceuticals Negative

ALPS Group Inc Ordinary Share has higher revenue and earnings than Phio Pharmaceuticals. Phio Pharmaceuticals is trading at a lower price-to-earnings ratio than ALPS Group Inc Ordinary Share, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
ALPS Group Inc Ordinary Share$4.86M13.01-$2.01M$0.331.15
Phio PharmaceuticalsN/AN/A-$8.70M-$1.29N/A

Summary

ALPS Group Inc Ordinary Share beats Phio Pharmaceuticals on 8 of the 14 factors compared between the two stocks.

How does Phio Pharmaceuticals compare to Instil Bio?

Instil Bio (NASDAQ:TIL) and Phio Pharmaceuticals (NASDAQ:PHIO) are both small-cap healthcare companies, but which is the better investment? We will compare the two businesses based on the strength of their risk, valuation, institutional ownership, analyst recommendations, earnings, profitability, media sentiment and dividends.

Instil Bio's return on equity of -26.78% beat Phio Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Instil BioN/A -26.78% -14.89%
Phio Pharmaceuticals N/A -87.41%-79.76%

60.6% of Instil Bio shares are held by institutional investors. Comparatively, 57.3% of Phio Pharmaceuticals shares are held by institutional investors. 47.0% of Instil Bio shares are held by insiders. Comparatively, 3.5% of Phio Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.

Instil Bio has a beta of 1.91, meaning that its stock price is 91% more volatile than the broader market. Comparatively, Phio Pharmaceuticals has a beta of 0.8, meaning that its stock price is 20% less volatile than the broader market.

Instil Bio is trading at a lower price-to-earnings ratio than Phio Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Instil BioN/AN/A-$71.37M-$4.47N/A
Phio PharmaceuticalsN/AN/A-$8.70M-$1.29N/A

In the previous week, Phio Pharmaceuticals had 5 more articles in the media than Instil Bio. MarketBeat recorded 5 mentions for Phio Pharmaceuticals and 0 mentions for Instil Bio. Instil Bio's average media sentiment score of 0.00 beat Phio Pharmaceuticals' score of -0.80 indicating that Instil Bio is being referred to more favorably in the media.

Company Overall Sentiment
Instil Bio Neutral
Phio Pharmaceuticals Negative

Instil Bio presently has a consensus target price of $66.00, suggesting a potential upside of 761.62%. Phio Pharmaceuticals has a consensus target price of $14.00, suggesting a potential upside of 1,161.26%. Given Phio Pharmaceuticals' stronger consensus rating and higher possible upside, analysts clearly believe Phio Pharmaceuticals is more favorable than Instil Bio.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Instil Bio
1 Sell rating(s)
2 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.67
Phio Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00

Summary

Phio Pharmaceuticals beats Instil Bio on 7 of the 13 factors compared between the two stocks.

How does Phio Pharmaceuticals compare to TScan Therapeutics?

Phio Pharmaceuticals (NASDAQ:PHIO) and TScan Therapeutics (NASDAQ:TCRX) are both small-cap healthcare companies, but which is the superior stock? We will compare the two businesses based on the strength of their media sentiment, risk, earnings, profitability, institutional ownership, dividends, analyst recommendations and valuation.

57.3% of Phio Pharmaceuticals shares are owned by institutional investors. Comparatively, 82.8% of TScan Therapeutics shares are owned by institutional investors. 3.5% of Phio Pharmaceuticals shares are owned by company insiders. Comparatively, 6.3% of TScan Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

In the previous week, Phio Pharmaceuticals and Phio Pharmaceuticals both had 5 articles in the media. TScan Therapeutics' average media sentiment score of -0.61 beat Phio Pharmaceuticals' score of -0.80 indicating that TScan Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Phio Pharmaceuticals
0 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Negative
TScan Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
3 Negative mention(s)
0 Very Negative mention(s)
Negative

Phio Pharmaceuticals has higher earnings, but lower revenue than TScan Therapeutics. Phio Pharmaceuticals is trading at a lower price-to-earnings ratio than TScan Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Phio PharmaceuticalsN/AN/A-$8.70M-$1.29N/A
TScan Therapeutics$10.32M2.44-$129.77M-$0.91N/A

Phio Pharmaceuticals currently has a consensus target price of $14.00, suggesting a potential upside of 1,161.26%. TScan Therapeutics has a consensus target price of $4.67, suggesting a potential upside of 1,158.20%. Given Phio Pharmaceuticals' higher probable upside, research analysts plainly believe Phio Pharmaceuticals is more favorable than TScan Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Phio Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00
TScan Therapeutics
1 Sell rating(s)
3 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.29

Phio Pharmaceuticals has a beta of 0.8, suggesting that its stock price is 20% less volatile than the broader market. Comparatively, TScan Therapeutics has a beta of 1.07, suggesting that its stock price is 7% more volatile than the broader market.

Phio Pharmaceuticals has a net margin of 0.00% compared to TScan Therapeutics' net margin of -1,655.35%. Phio Pharmaceuticals' return on equity of -87.41% beat TScan Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Phio PharmaceuticalsN/A -87.41% -79.76%
TScan Therapeutics -1,655.35%-108.72%-54.47%

Summary

TScan Therapeutics beats Phio Pharmaceuticals on 10 of the 14 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding PHIO and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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PHIO vs. The Competition

MetricPhio PharmaceuticalsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$13.13M$4.03B$7.26B$12.73B
Dividend YieldN/A3.60%2.53%8.86%
P/E Ratio-0.8612.66273.2925.38
Price / SalesN/A1,309.08613.4597.56
Price / CashN/A106.8777.8252.26
Price / Book1.0316.2912.896.14
Net Income-$8.70M-$22.72M$3.47B$349.01M
7 Day Performance-1.77%0.34%0.60%-0.27%
1 Month Performance4.72%8.52%5.73%0.68%
1 Year Performance-46.12%52.66%25.35%14.84%

Phio Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
PHIO
Phio Pharmaceuticals
3.2983 of 5 stars
$1.11
-1.8%
$14.00
+1,161.3%
-46.6%$13.13MN/AN/A10
APLM
Apollomics
1.5906 of 5 stars
$24.92
+7.8%
N/A+569.3%$55.18M$8.50MN/A45
ATYR
aTyr Pharma
0.3469 of 5 stars
$0.56
+4.7%
N/A-91.2%$54.44M$190KN/A53
ALPS
ALPS Group Inc Ordinary Share
0.5647 of 5 stars
$0.32
+1.6%
N/AN/A$53.25M$4.86M0.97N/A
TIL
Instil Bio
1.7925 of 5 stars
$7.70
-1.4%
$66.00
+757.1%
-73.6%$52.21MN/AN/A410

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This page (NASDAQ:PHIO) was last updated on 9/4/2026 by MarketBeat.com Staff.
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