Prime Medicine (PRME) Institutional Ownership

$2.78 -0.04 (-1.42%)

Closing price 04:00 PM Eastern

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$2.84 +0.06 (+1.98%)

As of 06:37 PM Eastern

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Current Institutional Ownership Percentage: 70.37%
Number of Institutional Buyers (last 12 months): 120
Total Institutional Inflows (last 12 months): $215.00M

Number of Institutional Sellers (last 12 months): 35
Total Institutional Outflows (last 12 months): $71.70M

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PRME Institutional Buying and Selling by Quarter

Prime Medicine Major Shareholders & Ownership History

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Reporting Date	Major Shareholder Name	Shares Held	Market Value	% of Portfolio	Quarterly Change in Shares	Ownership in Company
6/4/2026	Chelsea Counsel Co.	462,340	$1.61M	0.7%	+103.7%	0.256%
5/19/2026	Bank of America Corp DE	577,004	$2.01M	0.0%	-11.0%	0.319%
5/18/2026	ADAR1 Capital Management LLC	1,973,282	$6.87M	0.4%	N/A	1.093%
5/18/2026	Royal Bank of Canada	9,254	$32K	0.0%	+89.3%	0.005%
5/18/2026	Redmile Group LLC	1,590,832	$5.54M	0.4%	N/A	0.881%
5/14/2026	Renaissance Technologies LLC	741,039	$2.58M	0.0%	-35.5%	0.410%
5/14/2026	Sei Investments Co.	29,183	$102K	0.0%	N/A	0.016%
5/8/2026	Amova Asset Management Americas Inc.	2,940,793	$10.21M	0.1%	-9.4%	1.628%
5/7/2026	Dimensional Fund Advisors LP	304,522	$1.06M	0.0%	+262.3%	0.169%
5/7/2026	Swiss National Bank	178,600	$622K	0.0%	+5.0%	0.099%
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5/5/2026	Wealthfront Advisers LLC	10,379	$36K	0.0%	N/A	0.006%
5/5/2026	Bank of New York Mellon Corp	267,219	$930K	0.0%	+8.3%	0.148%
5/1/2026	Sequoia Financial Advisors LLC	11,673	$41K	0.0%	N/A	0.006%
4/30/2026	Sumitomo Mitsui Trust Group Inc.	2,940,793	$10.23M	0.0%	-9.4%	1.628%
4/27/2026	Turtle Creek Wealth Advisors LLC	25,000	$87K	0.0%	N/A	0.014%
4/22/2026	Pictet Asset Management Holding SA	12,107	$42K	0.0%	N/A	0.007%
4/16/2026	Thompson Davis & CO. Inc.	17,240	$60K	0.0%	-24.2%	0.010%
3/17/2026	Rockefeller Capital Management L.P.	121,391	$421K	0.0%	+10,557.7%	0.067%
3/3/2026	Caitong International Asset Management Co. Ltd	38,696	$134K	0.0%	N/A	0.021%
2/24/2026	Chelsea Counsel Co.	227,000	$788K	0.3%	+9.0%	0.126%
2/23/2026	Virtu Financial LLC	94,778	$329K	0.0%	+701.2%	0.053%
2/19/2026	T. Rowe Price Investment Management Inc.	5,995,183	$20.80M	0.0%	-35.0%	3.321%
2/19/2026	Invesco Ltd.	56,779	$197K	0.0%	-92.5%	0.031%
2/18/2026	XTX Topco Ltd	72,935	$253K	0.0%	+51.2%	0.040%
2/18/2026	Voloridge Investment Management LLC	23,121	$80K	0.0%	-86.4%	0.013%
2/18/2026	Virtus Investment Advisers LLC	64,886	$225K	0.1%	N/A	0.036%
2/18/2026	Wellington Management Group LLP	248,227	$861K	0.0%	+20.9%	0.138%
2/18/2026	Polymer Capital Management US LLC	35,981	$125K	0.0%	+73.1%	0.020%
2/18/2026	Quadrature Capital Ltd	52,866	$183K	0.0%	+419.2%	0.029%
2/18/2026	Millennium Management LLC	51,335	$178K	0.0%	-96.4%	0.028%
2/18/2026	MWG Caph Ltd	1,792,210	$6.22M	8.6%	N/A	0.993%
2/18/2026	Janus Henderson Group PLC	60,900	$210K	0.0%	N/A	0.034%
2/18/2026	Engineers Gate Manager LP	60,490	$210K	0.0%	+8.8%	0.034%
2/18/2026	Balyasny Asset Management L.P.	3,124,362	$10.84M	0.0%	+6,426.4%	1.731%
2/18/2026	Bridgeway Capital Management LLC	134,800	$468K	0.0%	-18.2%	0.075%
2/17/2026	Lazard Asset Management LLC	10,844	$38K	0.0%	N/A	0.006%
2/17/2026	Jump Financial LLC	171,931	$597K	0.0%	N/A	0.095%
2/17/2026	Farallon Capital Management LLC	1,240,843	$4.31M	0.0%	-73.9%	0.687%
2/17/2026	Price T Rowe Associates Inc. MD	104,553	$363K	0.0%	+40.3%	0.058%
2/17/2026	T. Rowe Price Investment Management Inc.	1,094,316	$3.80M	0.0%	-88.1%	0.606%
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2/17/2026	California State Teachers Retirement System	86,929	$302K	0.0%	+2,279.0%	0.048%
2/17/2026	&PARTNERS	60,352	$209K	0.0%	+409.4%	0.033%
2/17/2026	Graham Capital Management L.P.	114,680	$398K	0.0%	N/A	0.064%
2/16/2026	Squarepoint Ops LLC	218,042	$757K	0.0%	+450.6%	0.121%
2/16/2026	Verition Fund Management LLC	290,983	$1.01M	0.0%	N/A	0.161%
2/16/2026	Mariner LLC	36,290	$126K	0.0%	+99.2%	0.020%
2/16/2026	Glen Eagle Advisors LLC	10,000	$35K	0.0%	N/A	0.006%
2/16/2026	Barclays PLC	363,826	$1.26M	0.0%	+213.9%	0.202%
2/13/2026	The Manufacturers Life Insurance Company	31,602	$110K	0.0%	+16.5%	0.018%
2/13/2026	Walleye Capital LLC	46,139	$160K	0.0%	N/A	0.026%
2/13/2026	Rafferty Asset Management LLC	187,711	$651K	0.0%	N/A	0.104%
2/13/2026	Charles Schwab Investment Management Inc.	936,815	$3.25M	0.0%	+63.4%	0.519%
2/13/2026	State Street Corp	5,095,510	$17.68M	0.0%	+293.0%	2.823%
2/13/2026	Martingale Asset Management L P	14,808	$51K	0.0%	N/A	0.008%
2/13/2026	Caitong International Asset Management Co. Ltd	9,624	$33K	0.1%	N/A	0.005%
2/13/2026	UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	99,100	$344K	0.0%	N/A	0.055%
2/13/2026	Wells Fargo & Company MN	294,496	$1.02M	0.0%	+49.5%	0.163%
2/12/2026	Federation des caisses Desjardins du Quebec	12,000	$42K	0.0%	-24.5%	0.007%
2/12/2026	HRT Financial LP	655,351	$2.27M	0.0%	+195.9%	0.363%
2/12/2026	MetLife Investment Management LLC	57,570	$200K	0.0%	+33.9%	0.032%
2/12/2026	Commonwealth Equity Services LLC	34,399	$119K	0.0%	-45.5%	0.019%
2/12/2026	Renaissance Technologies LLC	1,149,159	$3.99M	0.0%	+1.3%	0.637%
2/12/2026	Dimensional Fund Advisors LP	84,054	$292K	0.0%	N/A	0.047%
2/12/2026	IQ EQ FUND MANAGEMENT IRELAND Ltd	178,519	$619K	0.0%	+47.8%	0.099%
2/12/2026	Steward Partners Investment Advisory LLC	118,406	$411K	0.0%	-6.3%	0.066%
2/12/2026	Swiss National Bank	170,100	$590K	0.0%	N/A	0.094%
2/12/2026	Nuveen LLC	251,636	$873K	0.0%	+11.4%	0.139%
2/11/2026	ARK Investment Management LLC	5,368,526	$18.63M	0.1%	-2.0%	2.974%
2/11/2026	Deutsche Bank AG	147,943	$513K	0.0%	+11.4%	0.082%
2/11/2026	Amova Asset Management Americas Inc.	3,245,506	$11.20M	0.1%	-10.6%	1.798%
2/10/2026	TD Asset Management Inc	94,148	$327K	0.0%	-48.0%	0.052%
2/10/2026	Goldman Sachs Group Inc.	1,755,768	$6.09M	0.0%	+327.5%	0.973%
2/10/2026	Greenwich Wealth Management LLC	740,001	$2.57M	0.1%	+2.8%	0.410%
2/10/2026	AXQ Capital LP	33,405	$116K	0.0%	-25.5%	0.019%
2/10/2026	Intech Investment Management LLC	35,036	$122K	0.0%	+50.8%	0.019%
2/9/2026	Kingsview Wealth Management LLC	15,000	$52K	0.0%	-39.4%	0.008%
2/9/2026	Geode Capital Management LLC	2,628,429	$9.12M	0.0%	+48.8%	1.456%
2/9/2026	Integrity Advisory Solutions LLC	11,689	$41K	0.0%	N/A	0.006%
2/9/2026	Sterling Investment Advisors Ltd.	13,400	$46K	0.0%	+34.0%	0.007%
2/6/2026	ProShare Advisors LLC	26,158	$91K	0.0%	+37.0%	0.014%
2/6/2026	HighTower Advisors LLC	400,110	$1.39M	0.0%	+19.9%	0.222%
2/2/2026	CENTRAL TRUST Co	34,995	$121K	0.0%	N/A	0.019%
2/2/2026	Oppenheimer & Co. Inc.	12,433	$43K	0.0%	N/A	0.007%
1/29/2026	UBS Group AG	2,440,583	$8.47M	0.0%	+700.8%	1.352%
1/28/2026	Arizona State Retirement System	24,085	$84K	0.0%	N/A	0.013%
1/27/2026	Zurcher Kantonalbank Zurich Cantonalbank	8,814	$31K	0.0%	N/A	0.005%
1/26/2026	Shelton Wealth Management LLC	20,066	$70K	0.0%	+15.8%	0.011%
1/23/2026	Transcend Capital Advisors LLC	26,500	$92K	0.0%	N/A	0.015%
1/23/2026	Sumitomo Mitsui Trust Group Inc.	3,245,506	$11.26M	0.0%	-10.6%	1.798%
1/23/2026	Elevate Capital Advisors LLC	42,666	$148K	0.1%	N/A	0.024%
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1/21/2026	Palumbo Wealth Management LLC	85,539	$297K	0.1%	-7.6%	0.047%
1/12/2026	Thompson Davis & CO. Inc.	22,740	$79K	0.0%	-17.5%	0.013%
1/9/2026	SG Americas Securities LLC	30,954	$107K	0.0%	N/A	0.017%
1/1/2026	JPMorgan Chase & Co.	43,389	$240K	0.0%	+31.3%	0.024%
1/1/2026	Tudor Investment Corp ET AL	62,981	$349K	0.0%	N/A	0.035%
12/15/2025	Hudson Bay Capital Management LP	13,025	$72K	0.0%	N/A	0.007%
12/9/2025	Tudor Investment Corp ET AL	62,981	$349K	0.0%	N/A	0.035%
11/17/2025	Keystone Financial Group	70,855	$393K	0.0%	N/A	0.039%
11/17/2025	Woodline Partners LP	3,002,482	$16.63M	0.1%	N/A	1.663%
11/17/2025	Polymer Capital Management US LLC	20,791	$115K	0.0%	N/A	0.012%

PRME Institutional Ownership - Frequently Asked Questions

During the previous two years, 173 institutional investors and hedge funds held shares of Prime Medicine. The most heavily invested institutionals were Alphabet Inc. ($91.76M), Vanguard Group Inc. ($27.27M), T. Rowe Price Investment Management Inc. ($20.80M), ARK Investment Management LLC ($18.63M), State Street Corp ($17.68M), Casdin Capital LLC ($17.55M), and Sumitomo Mitsui Trust Holdings Inc. ($16.65M).Learn more on Prime Medicine's institutional investors.

70.37% of Prime Medicine's stock is owned by institutional investors. Learn more on PRME's institutional investor holdings.

Of the 152 institutional investors that purchased Prime Medicine's stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: Farallon Capital Management LLC ($4M), State Street Corp ($3.84M), ARK Investment Management LLC ($3.29M), Balyasny Asset Management L.P. ($3.09M), Woodline Partners LP ($3.00M), RA Capital Management L.P. ($3M), and UBS Group AG ($2.25M).

Institutional investors have bought a total of 47,591,929 shares in the last 24 months. This purchase volume represents approximately $215.00M in transactions.

Of the 35 institutional investors that sold Prime Medicine's stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: T. Rowe Price Investment Management Inc. ($11.34M), Farallon Capital Management LLC ($3.51M), Sumitomo Mitsui Trust Group Inc. ($2.02M), Millennium Management LLC ($1.37M), Nikko Asset Management Americas Inc. ($1.34M), ARK Investment Management LLC ($881.83K), and Invesco Ltd. ($705.30K).

Institutional investors have sold a total of 23,880,724 shares in the last 24 months. This volume of shares sold represents approximately $71.70M in transactions.

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This page (NASDAQ:PRME) was last updated on 6/12/2026 by MarketBeat.com Staff.

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Prime Medicine (PRME) Institutional Ownership

PRME Institutional Buying and Selling by Quarter

Prime Medicine Major Shareholders & Ownership History

PRME Institutional Ownership - Frequently Asked Questions

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Prime Medicine (PRME) Institutional Ownership

Institutional Ownership Changes (13F Filings) for Prime Medicine (NASDAQ:PRME)

PRME Institutional Buying and Selling by Quarter

Prime Medicine Major Shareholders & Ownership History

PRME Institutional Ownership - Frequently Asked Questions

Who are the largest shareholders of PRME shares?

What percentage of Prime Medicine's stock is owned by institutional investors?

Which institutional investors have been buying Prime Medicine's stock?

How much institutional buying is happening at Prime Medicine?

Which of Prime Medicine's major shareholders have been selling company stock?

How much institutional selling is happening at Prime Medicine?

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