Go Pro
→ Major Buy Alert Issued for September 30th (From TradeSmith) (Ad)tc pixel Free PRME Stock Alerts

Prime Medicine (PRME) Institutional Ownership

Prime Medicine logo
$3.71 +0.04 (+1.09%)
As of 09/3/2026 04:00 PM Eastern
Compare

Institutional Ownership Changes (13F Filings) for Prime Medicine (NASDAQ:PRME)

Current
Institutional Ownership
Percentage
70.37%
Number of
Institutional Buyers
(last 12 months)
116
Total
Institutional Inflows
(last 12 months)
$329.56M
Number of
Institutional Sellers
(last 12 months)
29
Total
Institutional Outflows
(last 12 months)
$71.72M
Get PRME Insider Trade Alerts

Want to know when executives and insiders are buying or selling Prime Medicine stock? Sign up for InsiderTrades.com's daily newsletter to get the latest insider transactions delivered to your inbox daily.

Subscribe Now
SMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. By entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy.
Skip Chart & View Institutional Buying and Selling Data

PRME Institutional Buying and Selling by Quarter

Prime Medicine Major Shareholders & Ownership History

Export
Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
8/24/2026 California State Teachers Retirement System579,511$2.14M0.0%+570.2%0.320%
8/22/2026 Syon Capital LLC11,077$41K0.0%N/A0.006%
8/22/2026 Concurrent Investment Advisors LLC131,722$486K0.0%+77.6%0.073%
8/20/2026 Benjamin Edwards Inc.10,329$38K0.0%-25.4%0.006%
8/19/2026 Wellington Management Group LLP304,444$1.12M0.0%N/A0.168%
8/19/2026 Kingsview Wealth Management LLC10,000$37K0.0%N/A0.006%
8/17/2026 Corient Private Wealth LP38,881$143K0.0%N/A0.021%
8/17/2026 Bank of America Corp DE981,335$3.62M0.0%N/A0.541%
8/15/2026 Jupiter Topco LLC60,900$224K0.0%N/A0.034%
8/14/2026 ADAR1 Capital Management LLC1,997,552$7.37M0.3%N/A1.101%
8/14/2026 Legal & General Group Plc66,444$245K0.0%N/A0.037%
8/14/2026 The Manufacturers Life Insurance Company 27,353$101K0.0%N/A0.015%
8/13/2026 Cibc World Market Inc.18,662$69K0.0%N/A0.010%
8/13/2026 Sanctuary Advisors LLC13,400$49K0.0%N/A0.007%
8/13/2026 PEAK6 LLC208,057$768K0.0%N/A0.115%
8/12/2026 Ieq Capital LLC16,503$61K0.0%N/A0.009%
8/11/2026 Green Alpha Advisors LLC185,023$683K0.5%N/A0.102%
8/11/2026 E Fund Management Co. Ltd.20,484$76K0.0%N/A0.011%
8/8/2026 Wealthfront Advisers LLC11,301$42K0.0%N/A0.006%
8/7/2026 BlackRock Inc.9,602,041$35.43M0.0%N/A5.316%
8/7/2026 Deutsche Bank AG114,472$422K0.0%N/A0.063%
8/7/2026 Alphabet Inc.16,562,498$61.12M0.1%N/A9.170%
8/6/2026 Bank of New York Mellon Corp246,344$909K0.0%N/A0.136%
6/4/2026 Chelsea Counsel Co.462,340$1.61M0.7%+103.7%0.256%
5/19/2026 Bank of America Corp DE577,004$2.01M0.0%-11.0%0.319%
5/18/2026 ADAR1 Capital Management LLC1,973,282$6.87M0.4%N/A1.093%
5/18/2026 Royal Bank of Canada9,254$32K0.0%+89.3%0.005%
5/18/2026 Redmile Group LLC1,590,832$5.54M0.4%N/A0.881%
5/14/2026 Renaissance Technologies LLC741,039$2.58M0.0%-35.5%0.410%
5/14/2026 Sei Investments Co.29,183$102K0.0%N/A0.016%
5/8/2026 Amova Asset Management Americas Inc.2,940,793$10.21M0.1%-9.4%1.628%
5/7/2026 Dimensional Fund Advisors LP304,522$1.06M0.0%+262.3%0.169%
5/7/2026 Swiss National Bank178,600$622K0.0%+5.0%0.099%
5/5/2026 Wealthfront Advisers LLC10,379$36K0.0%N/A0.006%
5/5/2026 Bank of New York Mellon Corp267,219$930K0.0%+8.3%0.148%
5/1/2026 Sequoia Financial Advisors LLC11,673$41K0.0%N/A0.006%
4/30/2026 Sumitomo Mitsui Trust Group Inc.2,940,793$10.23M0.0%-9.4%1.628%
4/27/2026 Turtle Creek Wealth Advisors LLC25,000$87K0.0%N/A0.014%
4/22/2026 Pictet Asset Management Holding SA12,107$42K0.0%N/A0.007%
4/16/2026 Thompson Davis & CO. Inc.17,240$60K0.0%-24.2%0.010%
Bezos… DOOMED (Ad)

A single FCC filing hints Elon Musk is planning his biggest project yet - bigger than Tesla, SpaceX, and X combined - aimed at the $25 trillion AI industry. James Altucher says the plan could cut Amazon out of the AI race and disrupt Blue Origin, with a key deadline landing September 25.tc pixel

Watch James Altucher's free video breakdown before the September 25 deadline.
3/17/2026 Rockefeller Capital Management L.P.121,391$421K0.0%+10,557.7%0.067%
3/3/2026 Caitong International Asset Management Co. Ltd38,696$134K0.0%N/A0.021%
2/24/2026 Chelsea Counsel Co.227,000$788K0.3%+9.0%0.126%
2/23/2026 Virtu Financial LLC94,778$329K0.0%+701.2%0.053%
2/19/2026 T. Rowe Price Investment Management Inc.5,995,183$20.80M0.0%-35.0%3.321%
2/19/2026 Invesco Ltd.56,779$197K0.0%-92.5%0.031%
2/18/2026 XTX Topco Ltd72,935$253K0.0%+51.2%0.040%
2/18/2026 Voloridge Investment Management LLC23,121$80K0.0%-86.4%0.013%
2/18/2026 Virtus Investment Advisers LLC64,886$225K0.1%N/A0.036%
2/18/2026 Wellington Management Group LLP248,227$861K0.0%+20.9%0.138%
2/18/2026 Polymer Capital Management US LLC35,981$125K0.0%+73.1%0.020%
2/18/2026 Quadrature Capital Ltd52,866$183K0.0%+419.2%0.029%
2/18/2026 Millennium Management LLC51,335$178K0.0%-96.4%0.028%
2/18/2026MWG Caph Ltd1,792,210$6.22M8.6%N/A0.993%
2/18/2026Janus Henderson Group PLC60,900$210K0.0%N/A0.034%
2/18/2026 Engineers Gate Manager LP60,490$210K0.0%+8.8%0.034%
2/18/2026 Balyasny Asset Management L.P.3,124,362$10.84M0.0%+6,426.4%1.731%
2/18/2026 Bridgeway Capital Management LLC134,800$468K0.0%-18.2%0.075%
2/17/2026 Lazard Asset Management LLC10,844$38K0.0%N/A0.006%
2/17/2026 Jump Financial LLC171,931$597K0.0%N/A0.095%
2/17/2026 Farallon Capital Management LLC1,240,843$4.31M0.0%-73.9%0.687%
2/17/2026 Price T Rowe Associates Inc. MD104,553$363K0.0%+40.3%0.058%
2/17/2026 T. Rowe Price Investment Management Inc.1,094,316$3.80M0.0%-88.1%0.606%
2/17/2026 California State Teachers Retirement System86,929$302K0.0%+2,279.0%0.048%
2/17/2026 &PARTNERS60,352$209K0.0%+409.4%0.033%
2/17/2026 Graham Capital Management L.P.114,680$398K0.0%N/A0.064%
2/16/2026 Squarepoint Ops LLC218,042$757K0.0%+450.6%0.121%
2/16/2026 Verition Fund Management LLC290,983$1.01M0.0%N/A0.161%
2/16/2026 Mariner LLC36,290$126K0.0%+99.2%0.020%
2/16/2026 Glen Eagle Advisors LLC10,000$35K0.0%N/A0.006%
2/16/2026 Barclays PLC363,826$1.26M0.0%+213.9%0.202%
2/13/2026 The Manufacturers Life Insurance Company 31,602$110K0.0%+16.5%0.018%
2/13/2026 Walleye Capital LLC46,139$160K0.0%N/A0.026%
2/13/2026 Rafferty Asset Management LLC187,711$651K0.0%N/A0.104%
2/13/2026 Charles Schwab Investment Management Inc.936,815$3.25M0.0%+63.4%0.519%
2/13/2026 State Street Corp5,095,510$17.68M0.0%+293.0%2.823%
2/13/2026 Martingale Asset Management L P14,808$51K0.0%N/A0.008%
2/13/2026 Caitong International Asset Management Co. Ltd9,624$33K0.1%N/A0.005%
2/13/2026 UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC99,100$344K0.0%N/A0.055%
2/13/2026 Wells Fargo & Company MN294,496$1.02M0.0%+49.5%0.163%
2/12/2026 Federation des caisses Desjardins du Quebec12,000$42K0.0%-24.5%0.007%
2/12/2026 HRT Financial LP655,351$2.27M0.0%+195.9%0.363%
2/12/2026 MetLife Investment Management LLC57,570$200K0.0%+33.9%0.032%
2/12/2026 Commonwealth Equity Services LLC34,399$119K0.0%-45.5%0.019%
2/12/2026 Renaissance Technologies LLC1,149,159$3.99M0.0%+1.3%0.637%
2/12/2026 Dimensional Fund Advisors LP84,054$292K0.0%N/A0.047%
2/12/2026 IQ EQ FUND MANAGEMENT IRELAND Ltd178,519$619K0.0%+47.8%0.099%
2/12/2026 Steward Partners Investment Advisory LLC118,406$411K0.0%-6.3%0.066%
2/12/2026 Swiss National Bank170,100$590K0.0%N/A0.094%
2/12/2026 Nuveen LLC251,636$873K0.0%+11.4%0.139%
Before Anthropic becomes impossible to ignore... (Ad)

Riot Platforms just struck a 20-year, 191-megawatt data-center agreement tied to Anthropic, reportedly worth 9.1 billion dollars, according to CNBC. Before any Anthropic IPO arrives, one publicly accessible vehicle already lists Anthropic as its largest holding, available through a regular brokerage with no accredited-investor requirement. History showed how fast access tightened once SpaceX became a headline name. Alexander Green of The Oxford Club says this window is open now.tc pixel

Learn about this early Anthropic access opportunity before it closes
2/11/2026 ARK Investment Management LLC5,368,526$18.63M0.1%-2.0%2.974%
2/11/2026 Deutsche Bank AG147,943$513K0.0%+11.4%0.082%
2/11/2026 Amova Asset Management Americas Inc.3,245,506$11.20M0.1%-10.6%1.798%
2/10/2026 TD Asset Management Inc94,148$327K0.0%-48.0%0.052%
2/10/2026 Goldman Sachs Group Inc.1,755,768$6.09M0.0%+327.5%0.973%
2/10/2026 Greenwich Wealth Management LLC740,001$2.57M0.1%+2.8%0.410%
2/10/2026 AXQ Capital LP33,405$116K0.0%-25.5%0.019%
2/10/2026 Intech Investment Management LLC35,036$122K0.0%+50.8%0.019%
2/9/2026 Kingsview Wealth Management LLC15,000$52K0.0%-39.4%0.008%
2/9/2026 Geode Capital Management LLC2,628,429$9.12M0.0%+48.8%1.456%


PRME Institutional Ownership - Frequently Asked Questions

During the previous two years, 174 institutional investors and hedge funds held shares of Prime Medicine. The most heavily invested institutionals were Alphabet Inc. ($61.12M), BlackRock Inc. ($35.43M), Vanguard Group Inc. ($27.27M), T. Rowe Price Investment Management Inc. ($20.80M), ARK Investment Management LLC ($18.63M), State Street Corp ($17.68M), and Casdin Capital LLC ($17.55M).Learn more on Prime Medicine's institutional investors.

70.37% of Prime Medicine's stock is owned by institutional investors. Learn more on PRME's institutional investor holdings.

Of the 157 institutional investors that purchased Prime Medicine's stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: Alphabet Inc. ($18.06M), BlackRock Inc. ($9.60M), Farallon Capital Management LLC ($4M), ADAR1 Capital Management LLC ($3.97M), State Street Corp ($3.84M), ARK Investment Management LLC ($3.16M), and Balyasny Asset Management L.P. ($3.09M).

Institutional investors have bought a total of 77,625,291 shares in the last 24 months. This purchase volume represents approximately $329.56M in transactions.

Of the 29 institutional investors that sold Prime Medicine's stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: T. Rowe Price Investment Management Inc. ($11.34M), Farallon Capital Management LLC ($3.51M), Millennium Management LLC ($1.37M), Invesco Ltd. ($705.30K), Amova Asset Management Americas Inc. ($689.13K), Sumitomo Mitsui Trust Group Inc. ($689.13K), and Renaissance Technologies LLC ($408.12K).

Institutional investors have sold a total of 20,131,948 shares in the last 24 months. This volume of shares sold represents approximately $71.72M in transactions.


Related Companies

Institutional ownership data for NASDAQ:PRME is compiled from quarterly 13F filings submitted to the U.S. Securities and Exchange Commission (SEC), with the most recent received on 8/24/2026. New 13F filings are added each quarter as they're published.
From Our Partners
A Simple Guide to Options Trading While It's Still Free
A free copy of Options Trading Made Simple is available now but wont stay that way for long. Chris Rowe cal...
True Market Insiders | Sponsoredtc pixel
How Long Does $2.5M Last in Retirement?
Having $2.5 million saved puts you ahead of most Americans, but how long it lasts depends on the decisions you...
SmartAsset | Sponsoredtc pixel
Bezos… DOOMED
A single FCC filing hints Elon Musk is planning his biggest project yet - bigger than Tesla, SpaceX, and X com...
Paradigm Press | Sponsoredtc pixel
Before Anthropic becomes impossible to ignore...
Riot Platforms just struck a 20-year, 191-megawatt data-center agreement tied to Anthropic, reportedly worth 9...
The Oxford Club | Sponsoredtc pixel
Here’s the stock symbol I’ve promised
Whitney Tilson of Stansberry Research has long recommended Berkshire Hathaway as a core retirement holding - b...
Stansberry Research | Sponsoredtc pixel
Major Buy Alert Issued for September 30th
Keith Kaplan has invested $17 million into his own AI research tools, building a platform now used by 180,000 ...
TradeSmith | Sponsoredtc pixel
A new income category is drawing serious money - here's why
Forbes recently called a new category of exchange-traded income funds a 'golden era,' and Bloomberg noted the ...
Investors Alley | Sponsoredtc pixel
Three companies about to leapfrog Nvidia [And transform the entire industry]
In 1984, a 10000 dollar stake in Apple could have grown to 25 million dollars for early investors who simply g...
Eagle Publishing | Sponsoredtc pixel