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Prime Medicine (PRME) Competitors

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$3.39 +0.15 (+4.63%)
As of 08/21/2026 04:00 PM Eastern

PRME vs. BEAM, ADMA, PHVS, VCEL, and NUVB

Should you buy Prime Medicine stock or one of its competitors? Prime Medicine's main competitors and comparable companies include Beam Therapeutics (BEAM), ADMA Biologics (ADMA), Pharvaris (PHVS), Vericel (VCEL), and Nuvation Bio (NUVB). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Prime Medicine compare to Beam Therapeutics?

Beam Therapeutics (NASDAQ:BEAM) and Prime Medicine (NASDAQ:PRME) are both healthcare companies, but which is the better investment? We will compare the two businesses based on the strength of their earnings, risk, valuation, media sentiment, dividends, analyst recommendations, institutional ownership and profitability.

Beam Therapeutics has a beta of 2.23, indicating that its stock price is 123% more volatile than the broader market. Comparatively, Prime Medicine has a beta of 2.31, indicating that its stock price is 131% more volatile than the broader market.

Beam Therapeutics has a net margin of -54.75% compared to Prime Medicine's net margin of -4,613.11%. Beam Therapeutics' return on equity of -30.71% beat Prime Medicine's return on equity.

Company Net Margins Return on Equity Return on Assets
Beam Therapeutics-54.75% -30.71% -24.07%
Prime Medicine -4,613.11%-188.27%-59.11%

In the previous week, Beam Therapeutics and Beam Therapeutics both had 5 articles in the media. Beam Therapeutics' average media sentiment score of 1.17 beat Prime Medicine's score of 0.90 indicating that Beam Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Beam Therapeutics
4 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Prime Medicine
2 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Beam Therapeutics has higher revenue and earnings than Prime Medicine. Beam Therapeutics is trading at a lower price-to-earnings ratio than Prime Medicine, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Beam Therapeutics$139.74M22.00-$79.99M-$0.86N/A
Prime Medicine$4.63M132.80-$201.14M-$1.06N/A

99.7% of Beam Therapeutics shares are held by institutional investors. Comparatively, 70.4% of Prime Medicine shares are held by institutional investors. 3.8% of Beam Therapeutics shares are held by company insiders. Comparatively, 16.0% of Prime Medicine shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Beam Therapeutics currently has a consensus target price of $49.00, suggesting a potential upside of 64.65%. Prime Medicine has a consensus target price of $7.69, suggesting a potential upside of 126.97%. Given Prime Medicine's stronger consensus rating and higher possible upside, analysts plainly believe Prime Medicine is more favorable than Beam Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Beam Therapeutics
1 Sell rating(s)
2 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.69
Prime Medicine
1 Sell rating(s)
0 Hold rating(s)
7 Buy rating(s)
1 Strong Buy rating(s)
2.89

Summary

Beam Therapeutics beats Prime Medicine on 9 of the 16 factors compared between the two stocks.

How does Prime Medicine compare to ADMA Biologics?

Prime Medicine (NASDAQ:PRME) and ADMA Biologics (NASDAQ:ADMA) are both healthcare companies, but which is the superior business? We will contrast the two businesses based on the strength of their profitability, analyst recommendations, institutional ownership, dividends, risk, earnings, media sentiment and valuation.

Prime Medicine has a beta of 2.31, meaning that its stock price is 131% more volatile than the broader market. Comparatively, ADMA Biologics has a beta of 0.74, meaning that its stock price is 26% less volatile than the broader market.

ADMA Biologics has a net margin of 32.98% compared to Prime Medicine's net margin of -4,613.11%. ADMA Biologics' return on equity of 40.17% beat Prime Medicine's return on equity.

Company Net Margins Return on Equity Return on Assets
Prime Medicine-4,613.11% -188.27% -59.11%
ADMA Biologics 32.98%40.17%26.97%

In the previous week, Prime Medicine and Prime Medicine both had 5 articles in the media. Prime Medicine's average media sentiment score of 0.90 beat ADMA Biologics' score of 0.15 indicating that Prime Medicine is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Prime Medicine
2 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
ADMA Biologics
0 Very Positive mention(s)
0 Positive mention(s)
5 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

70.4% of Prime Medicine shares are held by institutional investors. Comparatively, 75.7% of ADMA Biologics shares are held by institutional investors. 16.0% of Prime Medicine shares are held by company insiders. Comparatively, 3.9% of ADMA Biologics shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.

ADMA Biologics has higher revenue and earnings than Prime Medicine. Prime Medicine is trading at a lower price-to-earnings ratio than ADMA Biologics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Prime Medicine$4.63M132.80-$201.14M-$1.06N/A
ADMA Biologics$512.28M4.30$146.93M$0.7014.06

Prime Medicine presently has a consensus target price of $7.69, indicating a potential upside of 126.97%. ADMA Biologics has a consensus target price of $18.67, indicating a potential upside of 89.70%. Given Prime Medicine's stronger consensus rating and higher possible upside, analysts clearly believe Prime Medicine is more favorable than ADMA Biologics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Prime Medicine
1 Sell rating(s)
0 Hold rating(s)
7 Buy rating(s)
1 Strong Buy rating(s)
2.89
ADMA Biologics
1 Sell rating(s)
2 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.33

Summary

Prime Medicine and ADMA Biologics tied by winning 8 of the 16 factors compared between the two stocks.

How does Prime Medicine compare to Pharvaris?

Pharvaris (NASDAQ:PHVS) and Prime Medicine (NASDAQ:PRME) are both healthcare companies, but which is the better stock? We will contrast the two businesses based on the strength of their dividends, institutional ownership, media sentiment, earnings, analyst recommendations, risk, profitability and valuation.

Pharvaris has a net margin of 0.00% compared to Prime Medicine's net margin of -4,613.11%. Pharvaris' return on equity of -61.40% beat Prime Medicine's return on equity.

Company Net Margins Return on Equity Return on Assets
PharvarisN/A -61.40% -56.00%
Prime Medicine -4,613.11%-188.27%-59.11%

In the previous week, Pharvaris had 12 more articles in the media than Prime Medicine. MarketBeat recorded 17 mentions for Pharvaris and 5 mentions for Prime Medicine. Prime Medicine's average media sentiment score of 0.90 beat Pharvaris' score of 0.05 indicating that Prime Medicine is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Pharvaris
4 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Neutral
Prime Medicine
2 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Pharvaris has a beta of -2.31, meaning that its share price is 331% less volatile than the broader market. Comparatively, Prime Medicine has a beta of 2.31, meaning that its share price is 131% more volatile than the broader market.

Pharvaris currently has a consensus target price of $51.08, indicating a potential upside of 40.82%. Prime Medicine has a consensus target price of $7.69, indicating a potential upside of 126.97%. Given Prime Medicine's stronger consensus rating and higher possible upside, analysts plainly believe Prime Medicine is more favorable than Pharvaris.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Pharvaris
1 Sell rating(s)
1 Hold rating(s)
11 Buy rating(s)
1 Strong Buy rating(s)
2.86
Prime Medicine
1 Sell rating(s)
0 Hold rating(s)
7 Buy rating(s)
1 Strong Buy rating(s)
2.89

70.4% of Prime Medicine shares are owned by institutional investors. 11.8% of Pharvaris shares are owned by insiders. Comparatively, 16.0% of Prime Medicine shares are owned by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth.

Pharvaris has higher earnings, but lower revenue than Prime Medicine. Pharvaris is trading at a lower price-to-earnings ratio than Prime Medicine, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
PharvarisN/AN/A-$198.79M-$3.05N/A
Prime Medicine$4.63M132.80-$201.14M-$1.06N/A

Summary

Prime Medicine beats Pharvaris on 9 of the 15 factors compared between the two stocks.

How does Prime Medicine compare to Vericel?

Prime Medicine (NASDAQ:PRME) and Vericel (NASDAQ:VCEL) are both healthcare companies, but which is the superior investment? We will compare the two companies based on the strength of their dividends, valuation, institutional ownership, risk, profitability, earnings, media sentiment and analyst recommendations.

Vericel has higher revenue and earnings than Prime Medicine. Prime Medicine is trading at a lower price-to-earnings ratio than Vericel, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Prime Medicine$4.63M132.80-$201.14M-$1.06N/A
Vericel$276.26M7.91$16.52M$0.4790.81

Vericel has a net margin of 7.91% compared to Prime Medicine's net margin of -4,613.11%. Vericel's return on equity of 6.91% beat Prime Medicine's return on equity.

Company Net Margins Return on Equity Return on Assets
Prime Medicine-4,613.11% -188.27% -59.11%
Vericel 7.91%6.91%5.02%

In the previous week, Vericel had 3 more articles in the media than Prime Medicine. MarketBeat recorded 8 mentions for Vericel and 5 mentions for Prime Medicine. Vericel's average media sentiment score of 1.54 beat Prime Medicine's score of 0.90 indicating that Vericel is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Prime Medicine
2 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Vericel
7 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive

Prime Medicine has a beta of 2.31, suggesting that its share price is 131% more volatile than the broader market. Comparatively, Vericel has a beta of 1.06, suggesting that its share price is 6% more volatile than the broader market.

Prime Medicine presently has a consensus price target of $7.69, indicating a potential upside of 126.97%. Vericel has a consensus price target of $58.40, indicating a potential upside of 36.83%. Given Prime Medicine's stronger consensus rating and higher possible upside, analysts plainly believe Prime Medicine is more favorable than Vericel.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Prime Medicine
1 Sell rating(s)
0 Hold rating(s)
7 Buy rating(s)
1 Strong Buy rating(s)
2.89
Vericel
0 Sell rating(s)
3 Hold rating(s)
4 Buy rating(s)
0 Strong Buy rating(s)
2.57

70.4% of Prime Medicine shares are owned by institutional investors. 16.0% of Prime Medicine shares are owned by insiders. Comparatively, 7.6% of Vericel shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term.

Summary

Vericel beats Prime Medicine on 9 of the 17 factors compared between the two stocks.

How does Prime Medicine compare to Nuvation Bio?

Nuvation Bio (NYSE:NUVB) and Prime Medicine (NASDAQ:PRME) are both healthcare companies, but which is the better stock? We will contrast the two businesses based on the strength of their valuation, profitability, dividends, analyst recommendations, media sentiment, institutional ownership, earnings and risk.

Prime Medicine has lower revenue, but higher earnings than Nuvation Bio. Nuvation Bio is trading at a lower price-to-earnings ratio than Prime Medicine, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Nuvation Bio$62.90M38.63-$204.63M-$0.44N/A
Prime Medicine$4.63M132.80-$201.14M-$1.06N/A

61.7% of Nuvation Bio shares are owned by institutional investors. Comparatively, 70.4% of Prime Medicine shares are owned by institutional investors. 30.1% of Nuvation Bio shares are owned by company insiders. Comparatively, 16.0% of Prime Medicine shares are owned by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

Nuvation Bio has a beta of 1.52, indicating that its share price is 52% more volatile than the broader market. Comparatively, Prime Medicine has a beta of 2.31, indicating that its share price is 131% more volatile than the broader market.

In the previous week, Nuvation Bio had 9 more articles in the media than Prime Medicine. MarketBeat recorded 14 mentions for Nuvation Bio and 5 mentions for Prime Medicine. Prime Medicine's average media sentiment score of 0.90 beat Nuvation Bio's score of 0.46 indicating that Prime Medicine is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Nuvation Bio
3 Very Positive mention(s)
2 Positive mention(s)
7 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Prime Medicine
2 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Nuvation Bio presently has a consensus price target of $13.00, suggesting a potential upside of 87.86%. Prime Medicine has a consensus price target of $7.69, suggesting a potential upside of 126.97%. Given Prime Medicine's stronger consensus rating and higher possible upside, analysts plainly believe Prime Medicine is more favorable than Nuvation Bio.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Nuvation Bio
1 Sell rating(s)
2 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.69
Prime Medicine
1 Sell rating(s)
0 Hold rating(s)
7 Buy rating(s)
1 Strong Buy rating(s)
2.89

Nuvation Bio has a net margin of -88.18% compared to Prime Medicine's net margin of -4,613.11%. Nuvation Bio's return on equity of -46.59% beat Prime Medicine's return on equity.

Company Net Margins Return on Equity Return on Assets
Nuvation Bio-88.18% -46.59% -22.01%
Prime Medicine -4,613.11%-188.27%-59.11%

Summary

Prime Medicine beats Nuvation Bio on 9 of the 17 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding PRME and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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PRME vs. The Competition

MetricPrime MedicineBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$614.87M$4.01B$7.37B$12.85B
Dividend YieldN/A3.64%2.53%11.08%
P/E Ratio-3.2011.62272.6024.24
Price / Sales132.801,338.17618.9699.78
Price / CashN/A105.1478.6253.99
Price / Book15.4116.8013.056.20
Net Income-$201.14M-$12.50M$3.47B$348.59M
7 Day Performance9.71%3.29%2.09%0.08%
1 Month Performance14.14%8.23%6.64%3.88%
1 Year PerformanceN/A55.05%25.02%16.98%

Prime Medicine Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
PRME
Prime Medicine
3.0525 of 5 stars
$3.39
+4.6%
$7.69
+127.0%
N/A$614.87M$4.63MN/AN/A
BEAM
Beam Therapeutics
2.1691 of 5 stars
$26.85
-1.6%
$49.00
+82.5%
+78.8%$2.82B$156.04MN/A510
ADMA
ADMA Biologics
3.9153 of 5 stars
$9.90
+1.5%
$18.67
+88.6%
-44.7%$2.26B$510.17M14.14530
PHVS
Pharvaris
3.691 of 5 stars
$34.42
-1.2%
$50.08
+45.5%
+56.9%$2.25BN/AN/A30
VCEL
Vericel
4.2311 of 5 stars
$44.35
+0.9%
$58.40
+31.7%
+15.3%$2.25B$276.26M94.36300

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This page (NASDAQ:PRME) was last updated on 8/23/2026 by MarketBeat.com Staff.
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