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Prime Medicine (PRME) Competitors

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$3.40 -0.15 (-4.23%)
Closing price 06/1/2026 04:00 PM Eastern
Extended Trading
$3.38 -0.02 (-0.59%)
As of 06/1/2026 06:35 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

PRME vs. BEAM, ZLAB, HCM, BHC, and TRVI

Should you buy Prime Medicine stock or one of its competitors? MarketBeat compares Prime Medicine with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Prime Medicine include Beam Therapeutics (BEAM), Zai Lab (ZLAB), HUTCHMED (HCM), Bausch Health Cos (BHC), and Trevi Therapeutics (TRVI). These companies are all part of the "pharmaceutical products" industry.

How does Prime Medicine compare to Beam Therapeutics?

Beam Therapeutics (NASDAQ:BEAM) and Prime Medicine (NASDAQ:PRME) are both pharmaceutical products companies, but which is the superior stock? We will contrast the two businesses based on the strength of their earnings, dividends, institutional ownership, media sentiment, risk, profitability, analyst recommendations and valuation.

Beam Therapeutics has a net margin of -39.66% compared to Prime Medicine's net margin of -4,917.55%. Beam Therapeutics' return on equity of -29.00% beat Prime Medicine's return on equity.

Company Net Margins Return on Equity Return on Assets
Beam Therapeutics-39.66% -29.00% -22.61%
Prime Medicine -4,917.55%-188.82%-60.97%

Beam Therapeutics has higher revenue and earnings than Prime Medicine. Beam Therapeutics is trading at a lower price-to-earnings ratio than Prime Medicine, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Beam Therapeutics$139.74M22.93-$79.99M-$0.68N/A
Prime Medicine$4.63M132.64-$201.14M-$1.23N/A

Beam Therapeutics has a beta of 2.25, suggesting that its share price is 125% more volatile than the broader market. Comparatively, Prime Medicine has a beta of 2.31, suggesting that its share price is 131% more volatile than the broader market.

In the previous week, Beam Therapeutics had 1 more articles in the media than Prime Medicine. MarketBeat recorded 3 mentions for Beam Therapeutics and 2 mentions for Prime Medicine. Prime Medicine's average media sentiment score of 0.94 beat Beam Therapeutics' score of 0.71 indicating that Prime Medicine is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Beam Therapeutics
0 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Prime Medicine
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Beam Therapeutics currently has a consensus price target of $46.83, indicating a potential upside of 50.40%. Prime Medicine has a consensus price target of $7.65, indicating a potential upside of 125.00%. Given Prime Medicine's higher possible upside, analysts clearly believe Prime Medicine is more favorable than Beam Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Beam Therapeutics
1 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
1 Strong Buy rating(s)
2.71
Prime Medicine
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
1 Strong Buy rating(s)
2.67

99.7% of Beam Therapeutics shares are owned by institutional investors. Comparatively, 70.4% of Prime Medicine shares are owned by institutional investors. 3.8% of Beam Therapeutics shares are owned by company insiders. Comparatively, 16.0% of Prime Medicine shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term.

Summary

Beam Therapeutics beats Prime Medicine on 10 of the 16 factors compared between the two stocks.

How does Prime Medicine compare to Zai Lab?

Zai Lab (NASDAQ:ZLAB) and Prime Medicine (NASDAQ:PRME) are both pharmaceutical products companies, but which is the superior investment? We will compare the two businesses based on the strength of their institutional ownership, earnings, valuation, media sentiment, risk, profitability, analyst recommendations and dividends.

Zai Lab has a net margin of -39.29% compared to Prime Medicine's net margin of -4,917.55%. Zai Lab's return on equity of -24.32% beat Prime Medicine's return on equity.

Company Net Margins Return on Equity Return on Assets
Zai Lab-39.29% -24.32% -15.52%
Prime Medicine -4,917.55%-188.82%-60.97%

Zai Lab has higher revenue and earnings than Prime Medicine. Zai Lab is trading at a lower price-to-earnings ratio than Prime Medicine, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Zai Lab$460.16M4.21-$175.54M-$1.62N/A
Prime Medicine$4.63M132.64-$201.14M-$1.23N/A

41.7% of Zai Lab shares are owned by institutional investors. Comparatively, 70.4% of Prime Medicine shares are owned by institutional investors. 4.9% of Zai Lab shares are owned by company insiders. Comparatively, 16.0% of Prime Medicine shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.

Zai Lab presently has a consensus target price of $45.83, suggesting a potential upside of 168.19%. Prime Medicine has a consensus target price of $7.65, suggesting a potential upside of 125.00%. Given Zai Lab's higher possible upside, research analysts clearly believe Zai Lab is more favorable than Prime Medicine.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Zai Lab
2 Sell rating(s)
0 Hold rating(s)
5 Buy rating(s)
1 Strong Buy rating(s)
2.63
Prime Medicine
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
1 Strong Buy rating(s)
2.67

In the previous week, Zai Lab had 1 more articles in the media than Prime Medicine. MarketBeat recorded 3 mentions for Zai Lab and 2 mentions for Prime Medicine. Prime Medicine's average media sentiment score of 0.94 beat Zai Lab's score of 0.93 indicating that Prime Medicine is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Zai Lab
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Prime Medicine
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Zai Lab has a beta of 0.79, indicating that its stock price is 21% less volatile than the broader market. Comparatively, Prime Medicine has a beta of 2.31, indicating that its stock price is 131% more volatile than the broader market.

Summary

Zai Lab and Prime Medicine tied by winning 8 of the 16 factors compared between the two stocks.

How does Prime Medicine compare to HUTCHMED?

Prime Medicine (NASDAQ:PRME) and HUTCHMED (NASDAQ:HCM) are both small-cap pharmaceutical products companies, but which is the superior business? We will contrast the two businesses based on the strength of their risk, dividends, earnings, valuation, institutional ownership, profitability, analyst recommendations and media sentiment.

HUTCHMED has a net margin of 0.00% compared to Prime Medicine's net margin of -4,917.55%. HUTCHMED's return on equity of 0.00% beat Prime Medicine's return on equity.

Company Net Margins Return on Equity Return on Assets
Prime Medicine-4,917.55% -188.82% -60.97%
HUTCHMED N/A N/A N/A

HUTCHMED has higher revenue and earnings than Prime Medicine.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Prime Medicine$4.63M132.64-$201.14M-$1.23N/A
HUTCHMED$548.51M3.63$456.91MN/AN/A

In the previous week, Prime Medicine had 1 more articles in the media than HUTCHMED. MarketBeat recorded 2 mentions for Prime Medicine and 1 mentions for HUTCHMED. HUTCHMED's average media sentiment score of 1.87 beat Prime Medicine's score of 0.94 indicating that HUTCHMED is being referred to more favorably in the news media.

Company Overall Sentiment
Prime Medicine Positive
HUTCHMED Very Positive

70.4% of Prime Medicine shares are owned by institutional investors. Comparatively, 8.8% of HUTCHMED shares are owned by institutional investors. 16.0% of Prime Medicine shares are owned by company insiders. Comparatively, 3.6% of HUTCHMED shares are owned by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.

Prime Medicine has a beta of 2.31, meaning that its stock price is 131% more volatile than the broader market. Comparatively, HUTCHMED has a beta of 0.31, meaning that its stock price is 69% less volatile than the broader market.

Prime Medicine currently has a consensus price target of $7.65, suggesting a potential upside of 125.00%. HUTCHMED has a consensus price target of $16.80, suggesting a potential upside of 47.37%. Given Prime Medicine's stronger consensus rating and higher probable upside, research analysts clearly believe Prime Medicine is more favorable than HUTCHMED.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Prime Medicine
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
1 Strong Buy rating(s)
2.67
HUTCHMED
1 Sell rating(s)
2 Hold rating(s)
1 Buy rating(s)
1 Strong Buy rating(s)
2.40

Summary

Prime Medicine beats HUTCHMED on 8 of the 14 factors compared between the two stocks.

How does Prime Medicine compare to Bausch Health Cos?

Prime Medicine (NASDAQ:PRME) and Bausch Health Cos (NYSE:BHC) are both pharmaceutical products companies, but which is the better business? We will contrast the two companies based on the strength of their earnings, dividends, institutional ownership, profitability, valuation, analyst recommendations, media sentiment and risk.

Bausch Health Cos has higher revenue and earnings than Prime Medicine. Prime Medicine is trading at a lower price-to-earnings ratio than Bausch Health Cos, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Prime Medicine$4.63M132.64-$201.14M-$1.23N/A
Bausch Health Cos$10.53B0.19$157M-$3.24N/A

Bausch Health Cos has a net margin of -11.47% compared to Prime Medicine's net margin of -4,917.55%. Prime Medicine's return on equity of -188.82% beat Bausch Health Cos' return on equity.

Company Net Margins Return on Equity Return on Assets
Prime Medicine-4,917.55% -188.82% -60.97%
Bausch Health Cos -11.47%-2,922.77%5.63%

70.4% of Prime Medicine shares are held by institutional investors. Comparatively, 78.7% of Bausch Health Cos shares are held by institutional investors. 16.0% of Prime Medicine shares are held by company insiders. Comparatively, 20.7% of Bausch Health Cos shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock is poised for long-term growth.

In the previous week, Bausch Health Cos had 1 more articles in the media than Prime Medicine. MarketBeat recorded 3 mentions for Bausch Health Cos and 2 mentions for Prime Medicine. Prime Medicine's average media sentiment score of 0.94 beat Bausch Health Cos' score of 0.20 indicating that Prime Medicine is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Prime Medicine
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Bausch Health Cos
1 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Prime Medicine has a beta of 2.31, meaning that its share price is 131% more volatile than the broader market. Comparatively, Bausch Health Cos has a beta of 0.42, meaning that its share price is 58% less volatile than the broader market.

Prime Medicine currently has a consensus price target of $7.65, suggesting a potential upside of 125.00%. Bausch Health Cos has a consensus price target of $8.00, suggesting a potential upside of 50.52%. Given Prime Medicine's stronger consensus rating and higher probable upside, equities analysts clearly believe Prime Medicine is more favorable than Bausch Health Cos.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Prime Medicine
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
1 Strong Buy rating(s)
2.67
Bausch Health Cos
1 Sell rating(s)
4 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.80

Summary

Prime Medicine beats Bausch Health Cos on 9 of the 17 factors compared between the two stocks.

How does Prime Medicine compare to Trevi Therapeutics?

Trevi Therapeutics (NASDAQ:TRVI) and Prime Medicine (NASDAQ:PRME) are both pharmaceutical products companies, but which is the superior business? We will compare the two companies based on the strength of their analyst recommendations, profitability, valuation, institutional ownership, earnings, dividends, risk and media sentiment.

Trevi Therapeutics currently has a consensus price target of $22.90, indicating a potential upside of 64.16%. Prime Medicine has a consensus price target of $7.65, indicating a potential upside of 125.00%. Given Prime Medicine's higher possible upside, analysts clearly believe Prime Medicine is more favorable than Trevi Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Trevi Therapeutics
1 Sell rating(s)
0 Hold rating(s)
9 Buy rating(s)
2 Strong Buy rating(s)
3.00
Prime Medicine
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
1 Strong Buy rating(s)
2.67

Trevi Therapeutics has a beta of 1.04, meaning that its stock price is 4% more volatile than the broader market. Comparatively, Prime Medicine has a beta of 2.31, meaning that its stock price is 131% more volatile than the broader market.

In the previous week, Prime Medicine had 1 more articles in the media than Trevi Therapeutics. MarketBeat recorded 2 mentions for Prime Medicine and 1 mentions for Trevi Therapeutics. Trevi Therapeutics' average media sentiment score of 1.89 beat Prime Medicine's score of 0.94 indicating that Trevi Therapeutics is being referred to more favorably in the media.

Company Overall Sentiment
Trevi Therapeutics Very Positive
Prime Medicine Positive

Trevi Therapeutics has higher earnings, but lower revenue than Prime Medicine. Trevi Therapeutics is trading at a lower price-to-earnings ratio than Prime Medicine, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Trevi TherapeuticsN/AN/A-$42.76M-$0.32N/A
Prime Medicine$4.63M132.64-$201.14M-$1.23N/A

95.8% of Trevi Therapeutics shares are held by institutional investors. Comparatively, 70.4% of Prime Medicine shares are held by institutional investors. 18.3% of Trevi Therapeutics shares are held by company insiders. Comparatively, 16.0% of Prime Medicine shares are held by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock is poised for long-term growth.

Trevi Therapeutics has a net margin of 0.00% compared to Prime Medicine's net margin of -4,917.55%. Trevi Therapeutics' return on equity of -24.53% beat Prime Medicine's return on equity.

Company Net Margins Return on Equity Return on Assets
Trevi TherapeuticsN/A -24.53% -23.37%
Prime Medicine -4,917.55%-188.82%-60.97%

Summary

Trevi Therapeutics beats Prime Medicine on 11 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding PRME and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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PRME vs. The Competition

MetricPrime MedicineBiological Products, Except Diagnostic Substances IndustryManufacturing SectorNASDAQ Exchange
Market Cap$641.19M$459.80M$4.38B$12.56B
Dividend YieldN/AN/A6.84%5.30%
P/E Ratio-2.76N/A21.7426.63
Price / Sales132.64335.47205.21112.54
Price / CashN/AN/A57.5237.60
Price / Book5.072.7833.856.88
Net Income-$201.14M-$81.71M$111.12M$336.73M
7 Day Performance14.48%3.42%2.06%3.07%
1 Month Performance-0.29%1.48%5.97%7.13%
1 Year PerformanceN/AN/A17.37%38.42%

Prime Medicine Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
PRME
Prime Medicine
1.9311 of 5 stars
$3.40
-4.2%
$7.65
+125.0%
N/A$641.19M$4.63MN/AN/A
BEAM
Beam Therapeutics
2.1212 of 5 stars
$29.79
+4.0%
$46.83
+57.2%
+97.8%$2.95B$164.01MN/A510
ZLAB
Zai Lab
3.42 of 5 stars
$18.45
-0.9%
$45.83
+148.4%
-43.6%$2.11B$460.16MN/A1,784
HCM
HUTCHMED
3.9813 of 5 stars
$11.75
-2.0%
$16.88
+43.6%
-17.2%$2.09B$548.51MN/A1,796
BHC
Bausch Health Cos
3.0805 of 5 stars
$5.39
-1.5%
$8.00
+48.4%
+17.3%$2.04B$10.53BN/A20,300

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This page (NASDAQ:PRME) was last updated on 6/2/2026 by MarketBeat.com Staff.
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