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Prime Medicine (PRME) Competitors

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$2.92 0.00 (0.00%)
Closing price 07/31/2026 04:00 PM Eastern
Extended Trading
$2.94 +0.02 (+0.68%)
As of 07/31/2026 07:34 PM Eastern
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PRME vs. BEAM, MLYS, PHVS, NUVB, and MESO

Should you buy Prime Medicine stock or one of its competitors? MarketBeat compares Prime Medicine with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Prime Medicine include Beam Therapeutics (BEAM), Mineralys Therapeutics (MLYS), Pharvaris (PHVS), Nuvation Bio (NUVB), and Mesoblast (MESO).

How does Prime Medicine compare to Beam Therapeutics?

Prime Medicine (NASDAQ:PRME) and Beam Therapeutics (NASDAQ:BEAM) are both healthcare companies, but which is the better investment? We will compare the two businesses based on the strength of their profitability, media sentiment, earnings, institutional ownership, dividends, analyst recommendations, valuation and risk.

In the previous week, Beam Therapeutics had 6 more articles in the media than Prime Medicine. MarketBeat recorded 10 mentions for Beam Therapeutics and 4 mentions for Prime Medicine. Beam Therapeutics' average media sentiment score of 1.06 beat Prime Medicine's score of 0.81 indicating that Beam Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Prime Medicine
3 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Beam Therapeutics
7 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Prime Medicine presently has a consensus price target of $7.53, indicating a potential upside of 157.92%. Beam Therapeutics has a consensus price target of $46.85, indicating a potential upside of 83.57%. Given Prime Medicine's stronger consensus rating and higher possible upside, equities analysts plainly believe Prime Medicine is more favorable than Beam Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Prime Medicine
1 Sell rating(s)
0 Hold rating(s)
6 Buy rating(s)
1 Strong Buy rating(s)
2.88
Beam Therapeutics
1 Sell rating(s)
3 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.64

70.4% of Prime Medicine shares are owned by institutional investors. Comparatively, 99.7% of Beam Therapeutics shares are owned by institutional investors. 16.0% of Prime Medicine shares are owned by company insiders. Comparatively, 3.8% of Beam Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Beam Therapeutics has higher revenue and earnings than Prime Medicine. Beam Therapeutics is trading at a lower price-to-earnings ratio than Prime Medicine, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Prime Medicine$4.63M113.91-$201.14M-$1.23N/A
Beam Therapeutics$164.01M16.01-$79.99M-$0.68N/A

Prime Medicine has a beta of 2.31, suggesting that its share price is 131% more volatile than the broader market. Comparatively, Beam Therapeutics has a beta of 2.18, suggesting that its share price is 118% more volatile than the broader market.

Beam Therapeutics has a net margin of -39.66% compared to Prime Medicine's net margin of -4,917.55%. Beam Therapeutics' return on equity of -29.00% beat Prime Medicine's return on equity.

Company Net Margins Return on Equity Return on Assets
Prime Medicine-4,917.55% -188.82% -60.97%
Beam Therapeutics -39.66%-29.00%-22.61%

Summary

Beam Therapeutics beats Prime Medicine on 10 of the 17 factors compared between the two stocks.

How does Prime Medicine compare to Mineralys Therapeutics?

Mineralys Therapeutics (NASDAQ:MLYS) and Prime Medicine (NASDAQ:PRME) are both healthcare companies, but which is the better stock? We will compare the two companies based on the strength of their valuation, earnings, analyst recommendations, media sentiment, institutional ownership, dividends, risk and profitability.

In the previous week, Mineralys Therapeutics had 4 more articles in the media than Prime Medicine. MarketBeat recorded 8 mentions for Mineralys Therapeutics and 4 mentions for Prime Medicine. Mineralys Therapeutics' average media sentiment score of 1.00 beat Prime Medicine's score of 0.81 indicating that Mineralys Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Mineralys Therapeutics
6 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Prime Medicine
3 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

84.5% of Mineralys Therapeutics shares are held by institutional investors. Comparatively, 70.4% of Prime Medicine shares are held by institutional investors. 18.9% of Mineralys Therapeutics shares are held by company insiders. Comparatively, 16.0% of Prime Medicine shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth.

Mineralys Therapeutics has a beta of 0.66, meaning that its stock price is 34% less volatile than the broader market. Comparatively, Prime Medicine has a beta of 2.31, meaning that its stock price is 131% more volatile than the broader market.

Mineralys Therapeutics has a net margin of 0.00% compared to Prime Medicine's net margin of -4,917.55%. Mineralys Therapeutics' return on equity of -27.92% beat Prime Medicine's return on equity.

Company Net Margins Return on Equity Return on Assets
Mineralys TherapeuticsN/A -27.92% -26.98%
Prime Medicine -4,917.55%-188.82%-60.97%

Mineralys Therapeutics has higher earnings, but lower revenue than Prime Medicine. Mineralys Therapeutics is trading at a lower price-to-earnings ratio than Prime Medicine, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Mineralys TherapeuticsN/AN/A-$154.65M-$2.05N/A
Prime Medicine$4.63M113.91-$201.14M-$1.23N/A

Mineralys Therapeutics presently has a consensus target price of $49.33, suggesting a potential upside of 93.31%. Prime Medicine has a consensus target price of $7.53, suggesting a potential upside of 157.92%. Given Prime Medicine's stronger consensus rating and higher possible upside, analysts plainly believe Prime Medicine is more favorable than Mineralys Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Mineralys Therapeutics
1 Sell rating(s)
1 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.63
Prime Medicine
1 Sell rating(s)
0 Hold rating(s)
6 Buy rating(s)
1 Strong Buy rating(s)
2.88

Summary

Mineralys Therapeutics beats Prime Medicine on 8 of the 15 factors compared between the two stocks.

How does Prime Medicine compare to Pharvaris?

Pharvaris (NASDAQ:PHVS) and Prime Medicine (NASDAQ:PRME) are both healthcare companies, but which is the better investment? We will compare the two companies based on the strength of their risk, media sentiment, valuation, dividends, analyst recommendations, earnings, profitability and institutional ownership.

Pharvaris has a net margin of 0.00% compared to Prime Medicine's net margin of -4,917.55%. Pharvaris' return on equity of -67.56% beat Prime Medicine's return on equity.

Company Net Margins Return on Equity Return on Assets
PharvarisN/A -67.56% -61.13%
Prime Medicine -4,917.55%-188.82%-60.97%

Pharvaris presently has a consensus target price of $50.08, indicating a potential upside of 53.54%. Prime Medicine has a consensus target price of $7.53, indicating a potential upside of 157.92%. Given Prime Medicine's stronger consensus rating and higher possible upside, analysts clearly believe Prime Medicine is more favorable than Pharvaris.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Pharvaris
1 Sell rating(s)
2 Hold rating(s)
10 Buy rating(s)
1 Strong Buy rating(s)
2.79
Prime Medicine
1 Sell rating(s)
0 Hold rating(s)
6 Buy rating(s)
1 Strong Buy rating(s)
2.88

70.4% of Prime Medicine shares are held by institutional investors. 16.0% of Prime Medicine shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

In the previous week, Pharvaris and Pharvaris both had 4 articles in the media. Pharvaris' average media sentiment score of 1.54 beat Prime Medicine's score of 0.81 indicating that Pharvaris is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Pharvaris
4 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Very Positive
Prime Medicine
3 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Pharvaris has higher earnings, but lower revenue than Prime Medicine. Pharvaris is trading at a lower price-to-earnings ratio than Prime Medicine, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
PharvarisN/AN/A-$198.79M-$3.18N/A
Prime Medicine$4.63M113.91-$201.14M-$1.23N/A

Pharvaris has a beta of -2.31, indicating that its share price is 331% less volatile than the broader market. Comparatively, Prime Medicine has a beta of 2.31, indicating that its share price is 131% more volatile than the broader market.

Summary

Prime Medicine beats Pharvaris on 9 of the 14 factors compared between the two stocks.

How does Prime Medicine compare to Nuvation Bio?

Prime Medicine (NASDAQ:PRME) and Nuvation Bio (NYSE:NUVB) are both healthcare companies, but which is the superior stock? We will compare the two businesses based on the strength of their media sentiment, institutional ownership, analyst recommendations, profitability, risk, earnings, dividends and valuation.

In the previous week, Nuvation Bio had 8 more articles in the media than Prime Medicine. MarketBeat recorded 12 mentions for Nuvation Bio and 4 mentions for Prime Medicine. Nuvation Bio's average media sentiment score of 0.88 beat Prime Medicine's score of 0.81 indicating that Nuvation Bio is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Prime Medicine
3 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Nuvation Bio
4 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Prime Medicine presently has a consensus price target of $7.53, indicating a potential upside of 157.92%. Nuvation Bio has a consensus price target of $12.88, indicating a potential upside of 103.53%. Given Prime Medicine's stronger consensus rating and higher possible upside, equities analysts clearly believe Prime Medicine is more favorable than Nuvation Bio.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Prime Medicine
1 Sell rating(s)
0 Hold rating(s)
6 Buy rating(s)
1 Strong Buy rating(s)
2.88
Nuvation Bio
1 Sell rating(s)
2 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.64

70.4% of Prime Medicine shares are owned by institutional investors. Comparatively, 61.7% of Nuvation Bio shares are owned by institutional investors. 16.0% of Prime Medicine shares are owned by company insiders. Comparatively, 30.1% of Nuvation Bio shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company will outperform the market over the long term.

Prime Medicine has a beta of 2.31, suggesting that its share price is 131% more volatile than the broader market. Comparatively, Nuvation Bio has a beta of 1.52, suggesting that its share price is 52% more volatile than the broader market.

Nuvation Bio has a net margin of -102.06% compared to Prime Medicine's net margin of -4,917.55%. Nuvation Bio's return on equity of -44.10% beat Prime Medicine's return on equity.

Company Net Margins Return on Equity Return on Assets
Prime Medicine-4,917.55% -188.82% -60.97%
Nuvation Bio -102.06%-44.10%-23.80%

Prime Medicine has higher earnings, but lower revenue than Nuvation Bio. Nuvation Bio is trading at a lower price-to-earnings ratio than Prime Medicine, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Prime Medicine$4.63M113.91-$201.14M-$1.23N/A
Nuvation Bio$62.90M35.02-$204.63M-$0.43N/A

Summary

Nuvation Bio beats Prime Medicine on 9 of the 17 factors compared between the two stocks.

How does Prime Medicine compare to Mesoblast?

Mesoblast (NASDAQ:MESO) and Prime Medicine (NASDAQ:PRME) are both small-cap healthcare companies, but which is the superior business? We will contrast the two companies based on the strength of their dividends, media sentiment, risk, valuation, institutional ownership, earnings, analyst recommendations and profitability.

Mesoblast has a beta of 2.08, suggesting that its stock price is 108% more volatile than the broader market. Comparatively, Prime Medicine has a beta of 2.31, suggesting that its stock price is 131% more volatile than the broader market.

1.4% of Mesoblast shares are held by institutional investors. Comparatively, 70.4% of Prime Medicine shares are held by institutional investors. 18.8% of Mesoblast shares are held by insiders. Comparatively, 16.0% of Prime Medicine shares are held by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term.

Mesoblast has a net margin of 0.00% compared to Prime Medicine's net margin of -4,917.55%. Mesoblast's return on equity of 0.00% beat Prime Medicine's return on equity.

Company Net Margins Return on Equity Return on Assets
MesoblastN/A N/A N/A
Prime Medicine -4,917.55%-188.82%-60.97%

Mesoblast has higher revenue and earnings than Prime Medicine. Mesoblast is trading at a lower price-to-earnings ratio than Prime Medicine, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Mesoblast$17.20M107.00-$102.14M-$0.28N/A
Prime Medicine$4.63M113.91-$201.14M-$1.23N/A

In the previous week, Prime Medicine had 1 more articles in the media than Mesoblast. MarketBeat recorded 4 mentions for Prime Medicine and 3 mentions for Mesoblast. Prime Medicine's average media sentiment score of 0.81 beat Mesoblast's score of 0.00 indicating that Prime Medicine is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Mesoblast
0 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Prime Medicine
3 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Prime Medicine has a consensus price target of $7.53, suggesting a potential upside of 157.92%. Given Prime Medicine's stronger consensus rating and higher possible upside, analysts clearly believe Prime Medicine is more favorable than Mesoblast.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Mesoblast
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
1 Strong Buy rating(s)
2.50
Prime Medicine
1 Sell rating(s)
0 Hold rating(s)
6 Buy rating(s)
1 Strong Buy rating(s)
2.88

Summary

Prime Medicine beats Mesoblast on 9 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding PRME and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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PRME vs. The Competition

MetricPrime MedicineBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$527.41M$3.54B$6.86B$12.42B
Dividend YieldN/A3.78%2.59%10.03%
P/E Ratio-2.377.38282.3024.66
Price / Sales113.911,182.44561.3476.65
Price / CashN/A44.8028.6046.71
Price / Book4.3616.9610.986.07
Net Income-$201.14M-$12.56M$3.49B$347.99M
7 Day Performance-2.99%-1.76%-0.60%-0.44%
1 Month Performance-24.55%-8.38%-5.20%-4.81%
1 Year PerformanceN/A48.40%62.01%18.61%

Prime Medicine Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
PRME
Prime Medicine
3.2231 of 5 stars
$2.92
flat
$7.53
+157.9%
N/A$527.41M$4.63MN/AN/A
BEAM
Beam Therapeutics
2.5419 of 5 stars
$27.29
+3.6%
$46.85
+71.7%
+35.5%$2.71B$164.01MN/A510
MLYS
Mineralys Therapeutics
3.6782 of 5 stars
$27.52
+3.0%
$49.33
+79.3%
+86.8%$2.20BN/AN/A28
PHVS
Pharvaris
3.6306 of 5 stars
$34.45
+2.7%
$50.08
+45.4%
+63.1%$2.19BN/AN/A30
NUVB
Nuvation Bio
3.6448 of 5 stars
$6.41
+2.3%
$12.38
+93.2%
+185.0%$2.18B$143.05MN/A60

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This page (NASDAQ:PRME) was last updated on 8/3/2026 by MarketBeat.com Staff.
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