Prime Medicine (PRME) Competitors

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$3.37 +0.14 (+4.33%)
Closing price 06/22/2026 04:00 PM Eastern
Extended Trading
$3.32 -0.06 (-1.63%)
As of 04:11 AM Eastern
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PRME vs. BEAM, NTLA, TRVI, PHVS, and AUPH

Should you buy Prime Medicine stock or one of its competitors? MarketBeat compares Prime Medicine with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Prime Medicine include Beam Therapeutics (BEAM), Intellia Therapeutics (NTLA), Trevi Therapeutics (TRVI), Pharvaris (PHVS), and Aurinia Pharmaceuticals (AUPH). These companies are all part of the "pharmaceutical products" industry.

How does Prime Medicine compare to Beam Therapeutics?

Prime Medicine (NASDAQ:PRME) and Beam Therapeutics (NASDAQ:BEAM) are both pharmaceutical products companies, but which is the better business? We will compare the two companies based on the strength of their dividends, analyst recommendations, risk, media sentiment, profitability, institutional ownership, valuation and earnings.

Beam Therapeutics has a net margin of -39.66% compared to Prime Medicine's net margin of -4,917.55%. Beam Therapeutics' return on equity of -29.00% beat Prime Medicine's return on equity.

Company Net Margins Return on Equity Return on Assets
Prime Medicine-4,917.55% -188.82% -60.97%
Beam Therapeutics -39.66%-29.00%-22.61%

Prime Medicine currently has a consensus target price of $7.38, suggesting a potential upside of 118.84%. Beam Therapeutics has a consensus target price of $46.83, suggesting a potential upside of 31.81%. Given Prime Medicine's stronger consensus rating and higher possible upside, equities analysts clearly believe Prime Medicine is more favorable than Beam Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Prime Medicine
1 Sell rating(s)
0 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.83
Beam Therapeutics
1 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
1 Strong Buy rating(s)
2.71

70.4% of Prime Medicine shares are owned by institutional investors. Comparatively, 99.7% of Beam Therapeutics shares are owned by institutional investors. 16.0% of Prime Medicine shares are owned by company insiders. Comparatively, 3.8% of Beam Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

Prime Medicine has a beta of 2.31, suggesting that its share price is 131% more volatile than the broader market. Comparatively, Beam Therapeutics has a beta of 2.25, suggesting that its share price is 125% more volatile than the broader market.

Beam Therapeutics has higher revenue and earnings than Prime Medicine. Beam Therapeutics is trading at a lower price-to-earnings ratio than Prime Medicine, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Prime Medicine$4.63M131.47-$201.14M-$1.23N/A
Beam Therapeutics$139.74M26.16-$79.99M-$0.68N/A

In the previous week, Beam Therapeutics had 6 more articles in the media than Prime Medicine. MarketBeat recorded 8 mentions for Beam Therapeutics and 2 mentions for Prime Medicine. Beam Therapeutics' average media sentiment score of 0.92 beat Prime Medicine's score of 0.00 indicating that Beam Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Prime Medicine
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Beam Therapeutics
4 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Summary

Beam Therapeutics beats Prime Medicine on 10 of the 16 factors compared between the two stocks.

How does Prime Medicine compare to Intellia Therapeutics?

Prime Medicine (NASDAQ:PRME) and Intellia Therapeutics (NASDAQ:NTLA) are both pharmaceutical products companies, but which is the better stock? We will compare the two businesses based on the strength of their profitability, media sentiment, earnings, analyst recommendations, valuation, risk, dividends and institutional ownership.

Prime Medicine has a beta of 2.31, meaning that its stock price is 131% more volatile than the broader market. Comparatively, Intellia Therapeutics has a beta of 1.92, meaning that its stock price is 92% more volatile than the broader market.

In the previous week, Intellia Therapeutics had 2 more articles in the media than Prime Medicine. MarketBeat recorded 4 mentions for Intellia Therapeutics and 2 mentions for Prime Medicine. Intellia Therapeutics' average media sentiment score of 0.42 beat Prime Medicine's score of 0.00 indicating that Intellia Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Prime Medicine
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Intellia Therapeutics
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Prime Medicine currently has a consensus target price of $7.38, indicating a potential upside of 118.84%. Intellia Therapeutics has a consensus target price of $20.46, indicating a potential upside of 29.88%. Given Prime Medicine's stronger consensus rating and higher possible upside, equities analysts clearly believe Prime Medicine is more favorable than Intellia Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Prime Medicine
1 Sell rating(s)
0 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.83
Intellia Therapeutics
3 Sell rating(s)
10 Hold rating(s)
9 Buy rating(s)
1 Strong Buy rating(s)
2.35

Intellia Therapeutics has a net margin of -597.04% compared to Prime Medicine's net margin of -4,917.55%. Intellia Therapeutics' return on equity of -57.47% beat Prime Medicine's return on equity.

Company Net Margins Return on Equity Return on Assets
Prime Medicine-4,917.55% -188.82% -60.97%
Intellia Therapeutics -597.04%-57.47%-46.24%

70.4% of Prime Medicine shares are owned by institutional investors. Comparatively, 88.8% of Intellia Therapeutics shares are owned by institutional investors. 16.0% of Prime Medicine shares are owned by company insiders. Comparatively, 3.5% of Intellia Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

Prime Medicine has higher earnings, but lower revenue than Intellia Therapeutics. Intellia Therapeutics is trading at a lower price-to-earnings ratio than Prime Medicine, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Prime Medicine$4.63M131.47-$201.14M-$1.23N/A
Intellia Therapeutics$67.67M32.52-$412.69M-$3.54N/A

Summary

Prime Medicine and Intellia Therapeutics tied by winning 8 of the 16 factors compared between the two stocks.

How does Prime Medicine compare to Trevi Therapeutics?

Trevi Therapeutics (NASDAQ:TRVI) and Prime Medicine (NASDAQ:PRME) are both pharmaceutical products companies, but which is the better business? We will compare the two businesses based on the strength of their media sentiment, earnings, dividends, valuation, institutional ownership, profitability, risk and analyst recommendations.

Trevi Therapeutics has a net margin of 0.00% compared to Prime Medicine's net margin of -4,917.55%. Trevi Therapeutics' return on equity of -24.53% beat Prime Medicine's return on equity.

Company Net Margins Return on Equity Return on Assets
Trevi TherapeuticsN/A -24.53% -23.37%
Prime Medicine -4,917.55%-188.82%-60.97%

Trevi Therapeutics presently has a consensus target price of $22.90, suggesting a potential upside of 29.31%. Prime Medicine has a consensus target price of $7.38, suggesting a potential upside of 118.84%. Given Prime Medicine's higher probable upside, analysts clearly believe Prime Medicine is more favorable than Trevi Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Trevi Therapeutics
1 Sell rating(s)
0 Hold rating(s)
9 Buy rating(s)
2 Strong Buy rating(s)
3.00
Prime Medicine
1 Sell rating(s)
0 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.83

95.8% of Trevi Therapeutics shares are owned by institutional investors. Comparatively, 70.4% of Prime Medicine shares are owned by institutional investors. 18.3% of Trevi Therapeutics shares are owned by insiders. Comparatively, 16.0% of Prime Medicine shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock will outperform the market over the long term.

Trevi Therapeutics has a beta of 1.04, suggesting that its share price is 4% more volatile than the broader market. Comparatively, Prime Medicine has a beta of 2.31, suggesting that its share price is 131% more volatile than the broader market.

In the previous week, Trevi Therapeutics had 1 more articles in the media than Prime Medicine. MarketBeat recorded 3 mentions for Trevi Therapeutics and 2 mentions for Prime Medicine. Trevi Therapeutics' average media sentiment score of 0.21 beat Prime Medicine's score of 0.00 indicating that Trevi Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Trevi Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Prime Medicine
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Trevi Therapeutics has higher earnings, but lower revenue than Prime Medicine. Trevi Therapeutics is trading at a lower price-to-earnings ratio than Prime Medicine, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Trevi TherapeuticsN/AN/A-$42.76M-$0.32N/A
Prime Medicine$4.63M131.47-$201.14M-$1.23N/A

Summary

Trevi Therapeutics beats Prime Medicine on 12 of the 16 factors compared between the two stocks.

How does Prime Medicine compare to Pharvaris?

Prime Medicine (NASDAQ:PRME) and Pharvaris (NASDAQ:PHVS) are both pharmaceutical products companies, but which is the superior investment? We will compare the two businesses based on the strength of their valuation, profitability, institutional ownership, media sentiment, earnings, risk, dividends and analyst recommendations.

70.4% of Prime Medicine shares are held by institutional investors. 16.0% of Prime Medicine shares are held by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock will outperform the market over the long term.

Pharvaris has a net margin of 0.00% compared to Prime Medicine's net margin of -4,917.55%. Pharvaris' return on equity of -67.56% beat Prime Medicine's return on equity.

Company Net Margins Return on Equity Return on Assets
Prime Medicine-4,917.55% -188.82% -60.97%
Pharvaris N/A -67.56%-61.13%

Prime Medicine currently has a consensus target price of $7.38, suggesting a potential upside of 118.84%. Pharvaris has a consensus target price of $49.18, suggesting a potential upside of 49.04%. Given Prime Medicine's stronger consensus rating and higher probable upside, equities analysts clearly believe Prime Medicine is more favorable than Pharvaris.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Prime Medicine
1 Sell rating(s)
0 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.83
Pharvaris
1 Sell rating(s)
2 Hold rating(s)
10 Buy rating(s)
0 Strong Buy rating(s)
2.69

Prime Medicine has a beta of 2.31, indicating that its share price is 131% more volatile than the broader market. Comparatively, Pharvaris has a beta of -2.35, indicating that its share price is 335% less volatile than the broader market.

Pharvaris has lower revenue, but higher earnings than Prime Medicine. Pharvaris is trading at a lower price-to-earnings ratio than Prime Medicine, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Prime Medicine$4.63M131.47-$201.14M-$1.23N/A
PharvarisN/AN/A-$198.79M-$3.18N/A

In the previous week, Pharvaris had 3 more articles in the media than Prime Medicine. MarketBeat recorded 5 mentions for Pharvaris and 2 mentions for Prime Medicine. Pharvaris' average media sentiment score of 0.39 beat Prime Medicine's score of 0.00 indicating that Pharvaris is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Prime Medicine
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Pharvaris
2 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Summary

Prime Medicine beats Pharvaris on 10 of the 16 factors compared between the two stocks.

How does Prime Medicine compare to Aurinia Pharmaceuticals?

Prime Medicine (NASDAQ:PRME) and Aurinia Pharmaceuticals (NASDAQ:AUPH) are both pharmaceutical products companies, but which is the superior business? We will compare the two companies based on the strength of their earnings, valuation, analyst recommendations, media sentiment, risk, dividends, profitability and institutional ownership.

Aurinia Pharmaceuticals has a net margin of 99.97% compared to Prime Medicine's net margin of -4,917.55%. Aurinia Pharmaceuticals' return on equity of 26.62% beat Prime Medicine's return on equity.

Company Net Margins Return on Equity Return on Assets
Prime Medicine-4,917.55% -188.82% -60.97%
Aurinia Pharmaceuticals 99.97%26.62%19.65%

70.4% of Prime Medicine shares are held by institutional investors. Comparatively, 36.8% of Aurinia Pharmaceuticals shares are held by institutional investors. 16.0% of Prime Medicine shares are held by insiders. Comparatively, 12.2% of Aurinia Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth.

Aurinia Pharmaceuticals has higher revenue and earnings than Prime Medicine. Prime Medicine is trading at a lower price-to-earnings ratio than Aurinia Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Prime Medicine$4.63M131.47-$201.14M-$1.23N/A
Aurinia Pharmaceuticals$298.30M7.56$287.20M$2.178.08

In the previous week, Prime Medicine had 1 more articles in the media than Aurinia Pharmaceuticals. MarketBeat recorded 2 mentions for Prime Medicine and 1 mentions for Aurinia Pharmaceuticals. Prime Medicine's average media sentiment score of 0.00 equaled Aurinia Pharmaceuticals'average media sentiment score.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Prime Medicine
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Aurinia Pharmaceuticals
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Prime Medicine currently has a consensus price target of $7.38, indicating a potential upside of 118.84%. Aurinia Pharmaceuticals has a consensus price target of $17.25, indicating a potential downside of 1.60%. Given Prime Medicine's stronger consensus rating and higher probable upside, equities analysts clearly believe Prime Medicine is more favorable than Aurinia Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Prime Medicine
1 Sell rating(s)
0 Hold rating(s)
4 Buy rating(s)
1 Strong Buy rating(s)
2.83
Aurinia Pharmaceuticals
0 Sell rating(s)
4 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.33

Prime Medicine has a beta of 2.31, suggesting that its share price is 131% more volatile than the broader market. Comparatively, Aurinia Pharmaceuticals has a beta of 1.41, suggesting that its share price is 41% more volatile than the broader market.

Summary

Prime Medicine beats Aurinia Pharmaceuticals on 9 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding PRME and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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PRME vs. The Competition

MetricPrime MedicineBiological Products, Except Diagnostic Substances IndustryManufacturing SectorNASDAQ Exchange
Market Cap$583.39M$469.49M$4.41B$12.54B
Dividend YieldN/AN/A10.94%5.81%
P/E Ratio-2.74N/A21.9724.33
Price / Sales131.47357.30165.03112.87
Price / CashN/AN/A41.0937.84
Price / Book5.032.7618.406.58
Net Income-$201.14M-$81.71M$115.37M$336.75M
7 Day Performance17.42%8.53%0.16%0.15%
1 Month Performance13.47%-0.32%-1.05%1.47%
1 Year PerformanceN/AN/A13.76%33.66%

Prime Medicine Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
PRME
Prime Medicine
1.6317 of 5 stars
$3.37
+4.3%
$7.38
+118.8%
N/A$583.39M$4.63MN/AN/A
BEAM
Beam Therapeutics
3.2805 of 5 stars
$30.99
-0.4%
$46.83
+51.1%
+112.0%$3.19B$164.01MN/A510
NTLA
Intellia Therapeutics
3.0755 of 5 stars
$14.55
-2.5%
$20.46
+40.6%
+71.2%$2.08B$66.09MN/A600
TRVI
Trevi Therapeutics
2.5727 of 5 stars
$15.40
+5.0%
$22.90
+48.7%
+197.1%$2.08BN/AN/A20
PHVS
Pharvaris
3.3948 of 5 stars
$31.46
-0.3%
$49.18
+56.3%
+83.4%$2.06BN/AN/A30

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This page (NASDAQ:PRME) was last updated on 6/23/2026 by MarketBeat.com Staff.
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