Tyra Biosciences (TYRA) Competitors $10.75 -0.28 (-2.54%) Closing price 08/7/2025 04:00 PM EasternExtended Trading$10.75 0.00 (0.00%) As of 08/7/2025 04:32 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock TYRA vs. XENE, AGIO, BEAM, ARWR, TWST, HRMY, IDYA, IRON, MESO, and CNTAShould you be buying Tyra Biosciences stock or one of its competitors? The main competitors of Tyra Biosciences include Xenon Pharmaceuticals (XENE), Agios Pharmaceuticals (AGIO), Beam Therapeutics (BEAM), Arrowhead Pharmaceuticals (ARWR), Twist Bioscience (TWST), Harmony Biosciences (HRMY), IDEAYA Biosciences (IDYA), Disc Medicine (IRON), Mesoblast (MESO), and Centessa Pharmaceuticals (CNTA). These companies are all part of the "pharmaceutical products" industry. Tyra Biosciences vs. Its Competitors Xenon Pharmaceuticals Agios Pharmaceuticals Beam Therapeutics Arrowhead Pharmaceuticals Twist Bioscience Harmony Biosciences IDEAYA Biosciences Disc Medicine Mesoblast Centessa Pharmaceuticals Tyra Biosciences (NASDAQ:TYRA) and Xenon Pharmaceuticals (NASDAQ:XENE) are both medical companies, but which is the better business? We will compare the two companies based on the strength of their valuation, media sentiment, dividends, analyst recommendations, risk, earnings, profitability and institutional ownership. Is TYRA or XENE more profitable? Tyra Biosciences' return on equity of -26.90% beat Xenon Pharmaceuticals' return on equity.Company Net Margins Return on Equity Return on Assets Tyra BiosciencesN/A -26.90% -25.54% Xenon Pharmaceuticals N/A -32.44%-30.84% Which has better valuation & earnings, TYRA or XENE? Tyra Biosciences has higher earnings, but lower revenue than Xenon Pharmaceuticals. Xenon Pharmaceuticals is trading at a lower price-to-earnings ratio than Tyra Biosciences, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioTyra BiosciencesN/AN/A-$86.48M-$1.63-6.60Xenon Pharmaceuticals$9.43M273.64-$234.33M-$3.23-10.41 Do institutionals & insiders hold more shares of TYRA or XENE? 84.1% of Tyra Biosciences shares are owned by institutional investors. Comparatively, 95.5% of Xenon Pharmaceuticals shares are owned by institutional investors. 15.2% of Tyra Biosciences shares are owned by company insiders. Comparatively, 5.5% of Xenon Pharmaceuticals shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock is poised for long-term growth. Does the media favor TYRA or XENE? In the previous week, Xenon Pharmaceuticals had 15 more articles in the media than Tyra Biosciences. MarketBeat recorded 18 mentions for Xenon Pharmaceuticals and 3 mentions for Tyra Biosciences. Xenon Pharmaceuticals' average media sentiment score of 0.77 beat Tyra Biosciences' score of 0.40 indicating that Xenon Pharmaceuticals is being referred to more favorably in the news media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Tyra Biosciences 1 Very Positive mention(s) 1 Positive mention(s) 0 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Neutral Xenon Pharmaceuticals 8 Very Positive mention(s) 3 Positive mention(s) 5 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Which has more risk and volatility, TYRA or XENE? Tyra Biosciences has a beta of 1.08, indicating that its stock price is 8% more volatile than the S&P 500. Comparatively, Xenon Pharmaceuticals has a beta of 1.16, indicating that its stock price is 16% more volatile than the S&P 500. Do analysts rate TYRA or XENE? Tyra Biosciences currently has a consensus target price of $30.83, indicating a potential upside of 186.82%. Xenon Pharmaceuticals has a consensus target price of $54.82, indicating a potential upside of 63.00%. Given Tyra Biosciences' higher probable upside, equities analysts plainly believe Tyra Biosciences is more favorable than Xenon Pharmaceuticals.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Tyra Biosciences 0 Sell rating(s) 0 Hold rating(s) 6 Buy rating(s) 0 Strong Buy rating(s) 3.00Xenon Pharmaceuticals 0 Sell rating(s) 0 Hold rating(s) 12 Buy rating(s) 0 Strong Buy rating(s) 3.00 SummaryTyra Biosciences beats Xenon Pharmaceuticals on 7 of the 13 factors compared between the two stocks. Get Tyra Biosciences News Delivered to You Automatically Sign up to receive the latest news and ratings for TYRA and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding TYRA and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart TYRA vs. The Competition Export to ExcelMetricTyra BiosciencesMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$585.58M$2.98B$5.42B$9.56BDividend YieldN/A2.46%3.99%4.14%P/E Ratio-6.6017.9729.9025.14Price / SalesN/A177.57372.1776.15Price / CashN/A41.8335.9458.58Price / Book1.597.238.105.59Net Income-$86.48M-$54.43M$3.26B$265.48M7 Day Performance3.66%0.22%0.65%1.22%1 Month Performance8.48%5.59%2.43%0.39%1 Year Performance-47.15%9.98%27.70%23.47% Tyra Biosciences Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)TYRATyra Biosciences1.6433 of 5 stars$10.75-2.5%$30.83+186.8%-44.9%$585.58MN/A-6.6020XENEXenon Pharmaceuticals3.0891 of 5 stars$30.97+2.2%$54.82+77.0%-16.7%$2.33B$9.43M-9.59210Positive NewsUpcoming EarningsOptions VolumeAGIOAgios Pharmaceuticals4.0503 of 5 stars$37.20-7.0%$56.33+51.4%-12.9%$2.32B$36.50M3.31390BEAMBeam Therapeutics2.755 of 5 stars$20.83-4.1%$48.75+134.0%-27.0%$2.18B$63.52M-4.52510Earnings ReportAnalyst ForecastAnalyst RevisionARWRArrowhead Pharmaceuticals3.8287 of 5 stars$16.20+2.9%$43.71+169.8%-35.8%$2.17B$3.55M-11.57400Positive NewsEarnings ReportAnalyst RevisionGap UpTWSTTwist Bioscience3.5447 of 5 stars$36.53+1.5%$50.40+38.0%-43.9%$2.16B$312.97M-11.24990News CoverageEarnings ReportAnalyst RevisionHRMYHarmony Biosciences4.7051 of 5 stars$35.76-4.7%$51.00+42.6%+1.9%$2.15B$744.85M13.65200Earnings ReportAnalyst RevisionIDYAIDEAYA Biosciences4.2007 of 5 stars$25.02+2.1%$48.09+92.2%-37.5%$2.15B$7M-6.9780Earnings ReportAnalyst RevisionGap UpHigh Trading VolumeIRONDisc Medicine3.2475 of 5 stars$59.48-1.9%$95.73+60.9%+38.3%$2.10BN/A-15.1730Earnings ReportMESOMesoblast0.7595 of 5 stars$15.93-2.6%$18.00+13.0%+160.0%$2.09B$5.90M0.0080News CoverageAnalyst UpgradeCNTACentessa Pharmaceuticals3.1102 of 5 stars$15.20-1.4%$28.10+84.9%+57.5%$2.06B$6.85M-8.40200Upcoming Earnings Related Companies and Tools Related Companies XENE Alternatives AGIO Alternatives BEAM Alternatives ARWR Alternatives TWST Alternatives HRMY Alternatives IDYA Alternatives IRON Alternatives MESO Alternatives CNTA Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:TYRA) was last updated on 8/8/2025 by MarketBeat.com Staff From Our PartnersProtect Your Bank Account with THESE 4 Simple StepsStarting as soon as a few months from now, the United States government will make a sweeping change to bank ac...Weiss Ratings | SponsoredAltucher: Trump’s Great Gain is startingNew Hampshire just launched a Strategic Crypto Reserve — and James Altucher says it’s the first sign that “Tru...Paradigm Press | SponsoredBREAKING: The House just passed 3 pro-crypto bills!THREE pro-crypto bills just passed the House! 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