Upstream Bio (UPB) Competitors $9.26 +0.28 (+3.12%) As of 04/30/2025 04:00 PM Eastern Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOwnershipSEC FilingsTrendsBuy This Stock UPB vs. VCEL, TWST, MTSR, SDGR, DNLI, MIRM, TARS, GMTX, BEAM, and NAMSShould you be buying Upstream Bio stock or one of its competitors? The main competitors of Upstream Bio include Vericel (VCEL), Twist Bioscience (TWST), Metsera (MTSR), Schrödinger (SDGR), Denali Therapeutics (DNLI), Mirum Pharmaceuticals (MIRM), Tarsus Pharmaceuticals (TARS), Gemini Therapeutics (GMTX), Beam Therapeutics (BEAM), and NewAmsterdam Pharma (NAMS). These companies are all part of the "pharmaceutical products" industry. Upstream Bio vs. Vericel Twist Bioscience Metsera Schrödinger Denali Therapeutics Mirum Pharmaceuticals Tarsus Pharmaceuticals Gemini Therapeutics Beam Therapeutics NewAmsterdam Pharma Vericel (NASDAQ:VCEL) and Upstream Bio (NASDAQ:UPB) are both small-cap medical companies, but which is the superior business? We will compare the two companies based on the strength of their risk, analyst recommendations, valuation, profitability, dividends, earnings, media sentiment, institutional ownership and community ranking. Does the MarketBeat Community prefer VCEL or UPB? Vericel received 351 more outperform votes than Upstream Bio when rated by MarketBeat users. However, 100.00% of users gave Upstream Bio an outperform vote while only 61.85% of users gave Vericel an outperform vote. CompanyUnderperformOutperformVericelOutperform Votes35561.85% Underperform Votes21938.15% Upstream BioOutperform Votes4100.00% Underperform VotesNo Votes Does the media refer more to VCEL or UPB? In the previous week, Vericel had 1 more articles in the media than Upstream Bio. MarketBeat recorded 8 mentions for Vericel and 7 mentions for Upstream Bio. Upstream Bio's average media sentiment score of 1.58 beat Vericel's score of 1.39 indicating that Upstream Bio is being referred to more favorably in the news media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Vericel 5 Very Positive mention(s) 1 Positive mention(s) 1 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Upstream Bio 6 Very Positive mention(s) 0 Positive mention(s) 0 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Very Positive Do analysts rate VCEL or UPB? Vericel presently has a consensus target price of $60.86, suggesting a potential upside of 60.07%. Upstream Bio has a consensus target price of $56.50, suggesting a potential upside of 510.15%. Given Upstream Bio's higher probable upside, analysts plainly believe Upstream Bio is more favorable than Vericel.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Vericel 0 Sell rating(s) 0 Hold rating(s) 7 Buy rating(s) 0 Strong Buy rating(s) 3.00Upstream Bio 0 Sell rating(s) 0 Hold rating(s) 4 Buy rating(s) 0 Strong Buy rating(s) 3.00 Is VCEL or UPB more profitable? Vericel has a net margin of 1.56% compared to Upstream Bio's net margin of 0.00%. Vericel's return on equity of 1.48% beat Upstream Bio's return on equity.Company Net Margins Return on Equity Return on Assets Vericel1.56% 1.48% 0.96% Upstream Bio N/A N/A N/A Which has higher earnings & valuation, VCEL or UPB? Upstream Bio has lower revenue, but higher earnings than Vericel. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioVericel$237.22M8.04-$3.18M$0.18211.22Upstream Bio$2.37M209.77N/AN/AN/A SummaryVericel beats Upstream Bio on 7 of the 11 factors compared between the two stocks. Get Upstream Bio News Delivered to You Automatically Sign up to receive the latest news and ratings for UPB and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding {thisCompany.Symbol} and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart UPB vs. The Competition Export to ExcelMetricUpstream BioPharmaceutical IndustryMedical SectorNASDAQ ExchangeMarket Cap$497.16M$6.89B$5.56B$7.83BDividend YieldN/A3.05%5.11%4.22%P/E RatioN/A7.4422.4418.48Price / Sales209.77242.70393.95103.59Price / CashN/A65.8538.1834.62Price / BookN/A6.516.774.25Net IncomeN/A$143.21M$3.22B$248.23M7 Day Performance3.35%1.98%1.45%0.89%1 Month Performance38.21%6.89%3.96%3.53%1 Year PerformanceN/A-2.52%16.07%5.08% Upstream Bio Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)UPBUpstream BioN/A$9.26+3.1%$56.50+510.2%N/A$497.16M$2.37M0.0038News CoveragePositive NewsVCELVericel2.3029 of 5 stars$40.87-0.9%$60.86+48.9%-17.1%$2.07B$237.22M681.28300Upcoming EarningsPositive NewsTWSTTwist Bioscience3.6043 of 5 stars$34.56-6.1%$52.80+52.8%+22.7%$2.06B$330.19M-10.22990Upcoming EarningsPositive NewsGap DownMTSRMetseraN/A$19.51-0.3%$47.00+140.9%N/A$2.05BN/A0.0081News CoverageHigh Trading VolumeSDGRSchrödinger2.2747 of 5 stars$26.19+1.7%$33.00+26.0%+5.1%$1.91B$207.54M-11.19790Upcoming EarningsGap DownDNLIDenali Therapeutics4.1332 of 5 stars$13.15+3.2%$37.57+185.7%+7.8%$1.91B$330.53M-4.76430Upcoming EarningsPositive NewsMIRMMirum Pharmaceuticals4.2328 of 5 stars$38.39-1.8%$58.20+51.6%+73.0%$1.90B$336.89M-19.00140Upcoming EarningsPositive NewsTARSTarsus Pharmaceuticals1.3692 of 5 stars$48.51-1.5%$63.67+31.2%+65.2%$1.86B$182.95M-12.7350Upcoming EarningsPositive NewsGMTXGemini TherapeuticsN/A$42.17+2.8%N/A+66.7%$1.83BN/A-42.1730BEAMBeam Therapeutics3.0229 of 5 stars$18.24+7.3%$49.45+171.1%-6.1%$1.82B$63.52M-10.36510Upcoming EarningsShort Interest ↑Gap DownHigh Trading VolumeNAMSNewAmsterdam Pharma3.1831 of 5 stars$16.26-0.5%$43.33+166.5%-12.3%$1.79B$45.56M-6.254Gap Down Related Companies and Tools Related Companies VCEL Alternatives TWST Alternatives MTSR Alternatives SDGR Alternatives DNLI Alternatives MIRM Alternatives TARS Alternatives GMTX Alternatives BEAM Alternatives NAMS Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:UPB) was last updated on 5/1/2025 by MarketBeat.com Staff From Our PartnersHow to invest in Elon Musk’s Optimus before its launchElon Musk is set to completely take over the AI industry with Optimus… A breakthrough AI-powered robot that El...InvestorPlace | SponsoredIs he more powerful than Trump? 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