Xenon Pharmaceuticals (XENE) Competitors $38.71 +0.11 (+0.28%) Closing price 08/29/2025 04:00 PM EasternExtended Trading$38.70 -0.02 (-0.04%) As of 08/29/2025 04:20 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock XENE vs. ASND, QGEN, MRNA, BBIO, ELAN, VRNA, ROIV, GRFS, RVMD, and RYTMShould you be buying Xenon Pharmaceuticals stock or one of its competitors? The main competitors of Xenon Pharmaceuticals include Ascendis Pharma A/S (ASND), QIAGEN (QGEN), Moderna (MRNA), BridgeBio Pharma (BBIO), Elanco Animal Health (ELAN), Verona Pharma PLC American Depositary Share (VRNA), Roivant Sciences (ROIV), Grifols (GRFS), Revolution Medicines (RVMD), and Rhythm Pharmaceuticals (RYTM). These companies are all part of the "pharmaceutical products" industry. Xenon Pharmaceuticals vs. Its Competitors Ascendis Pharma A/S QIAGEN Moderna BridgeBio Pharma Elanco Animal Health Verona Pharma PLC American Depositary Share Roivant Sciences Grifols Revolution Medicines Rhythm Pharmaceuticals Ascendis Pharma A/S (NASDAQ:ASND) and Xenon Pharmaceuticals (NASDAQ:XENE) are both medical companies, but which is the better investment? We will compare the two companies based on the strength of their analyst recommendations, risk, dividends, valuation, earnings, media sentiment, institutional ownership and profitability. Is ASND or XENE more profitable? Xenon Pharmaceuticals has a net margin of 0.00% compared to Ascendis Pharma A/S's net margin of -54.94%. Ascendis Pharma A/S's return on equity of 0.00% beat Xenon Pharmaceuticals' return on equity.Company Net Margins Return on Equity Return on Assets Ascendis Pharma A/S-54.94% N/A -24.31% Xenon Pharmaceuticals N/A -38.50%-36.47% Does the media prefer ASND or XENE? In the previous week, Ascendis Pharma A/S had 1 more articles in the media than Xenon Pharmaceuticals. MarketBeat recorded 12 mentions for Ascendis Pharma A/S and 11 mentions for Xenon Pharmaceuticals. Ascendis Pharma A/S's average media sentiment score of 1.51 beat Xenon Pharmaceuticals' score of 1.32 indicating that Ascendis Pharma A/S is being referred to more favorably in the media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Ascendis Pharma A/S 9 Very Positive mention(s) 1 Positive mention(s) 1 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Very Positive Xenon Pharmaceuticals 8 Very Positive mention(s) 1 Positive mention(s) 1 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Do analysts rate ASND or XENE? Ascendis Pharma A/S currently has a consensus price target of $243.36, indicating a potential upside of 25.27%. Xenon Pharmaceuticals has a consensus price target of $53.20, indicating a potential upside of 37.43%. Given Xenon Pharmaceuticals' higher possible upside, analysts plainly believe Xenon Pharmaceuticals is more favorable than Ascendis Pharma A/S.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Ascendis Pharma A/S 0 Sell rating(s) 0 Hold rating(s) 15 Buy rating(s) 0 Strong Buy rating(s) 3.00Xenon Pharmaceuticals 0 Sell rating(s) 0 Hold rating(s) 11 Buy rating(s) 0 Strong Buy rating(s) 3.00 Which has better valuation & earnings, ASND or XENE? Xenon Pharmaceuticals has lower revenue, but higher earnings than Ascendis Pharma A/S. Ascendis Pharma A/S is trading at a lower price-to-earnings ratio than Xenon Pharmaceuticals, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioAscendis Pharma A/S$490.75M24.23-$409.12M-$5.16-37.65Xenon Pharmaceuticals$7.50M397.97-$234.33M-$3.55-10.90 Do institutionals and insiders hold more shares of ASND or XENE? 95.4% of Xenon Pharmaceuticals shares are held by institutional investors. 40.0% of Ascendis Pharma A/S shares are held by company insiders. Comparatively, 4.1% of Xenon Pharmaceuticals shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term. Which has more risk and volatility, ASND or XENE? Ascendis Pharma A/S has a beta of 0.41, indicating that its stock price is 59% less volatile than the S&P 500. Comparatively, Xenon Pharmaceuticals has a beta of 1.16, indicating that its stock price is 16% more volatile than the S&P 500. SummaryXenon Pharmaceuticals beats Ascendis Pharma A/S on 8 of the 15 factors compared between the two stocks. Get Xenon Pharmaceuticals News Delivered to You Automatically Sign up to receive the latest news and ratings for XENE and its competitors with MarketBeat's FREE daily newsletter. Subscribe Now View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding XENE and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart XENE vs. The Competition Export to ExcelMetricXenon PharmaceuticalsMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$2.98B$3.07B$5.75B$9.76BDividend YieldN/A2.29%4.10%4.04%P/E Ratio-10.9020.7883.2726.59Price / Sales397.97386.98535.09111.49Price / CashN/A44.2237.4459.26Price / Book4.718.0710.556.58Net Income-$234.33M-$53.98M$3.27B$265.95M7 Day Performance-0.33%-0.88%0.40%0.17%1 Month Performance26.75%7.72%7.31%3.90%1 Year Performance-4.04%7.03%46.58%19.67% Xenon Pharmaceuticals Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)XENEXenon Pharmaceuticals2.2816 of 5 stars$38.71+0.3%$53.20+37.4%-4.0%$2.98B$7.50M-10.90210Positive NewsASNDAscendis Pharma A/S3.3509 of 5 stars$190.37-2.0%$243.36+27.8%+40.3%$11.89B$393.54M-36.891,017News CoveragePositive NewsQGENQIAGEN3.8018 of 5 stars$48.92-1.6%$49.69+1.6%+4.8%$11.06B$1.98B28.905,765Trending NewsAnalyst RevisionMRNAModerna4.5141 of 5 stars$25.35-6.5%$42.88+69.2%-68.9%$10.55B$3.24B-3.375,800BBIOBridgeBio Pharma4.2489 of 5 stars$47.29-3.6%$61.35+29.7%+85.9%$9.38B$235.81M-11.56400News CoveragePositive NewsAnalyst ForecastELANElanco Animal Health2.7754 of 5 stars$17.80-0.6%$17.33-2.6%+18.8%$8.90B$4.48B20.709,000VRNAVerona Pharma PLC American Depositary Share2.4269 of 5 stars$105.62+0.1%$109.00+3.2%+285.4%$8.64B$221.67M-106.6930Positive NewsROIVRoivant Sciences3.1813 of 5 stars$11.64-2.3%$16.50+41.8%-2.5%$8.14B$29.05M-16.63860News CoveragePositive NewsGRFSGrifols3.5521 of 5 stars$9.82-3.3%$10.30+4.9%+6.7%$6.99B$7.81B8.3923,822Positive NewsRVMDRevolution Medicines4.3506 of 5 stars$35.67-3.6%$69.92+96.0%-10.9%$6.92BN/A-7.93250News CoveragePositive NewsRYTMRhythm Pharmaceuticals3.5942 of 5 stars$99.20-3.9%$101.57+2.4%+118.1%$6.86B$130.13M-32.96140News CoveragePositive News Related Companies and Tools Related Companies Ascendis Pharma A/S Alternatives QIAGEN Alternatives Moderna Alternatives BridgeBio Pharma Alternatives Elanco Animal Health Alternatives Verona Pharma PLC American Depositary Share Alternatives Roivant Sciences Alternatives Grifols Alternatives Revolution Medicines Alternatives Rhythm Pharmaceuticals Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:XENE) was last updated on 8/31/2025 by MarketBeat.com Staff From Our PartnersINVESTOR ALERT: Tiny “$3 AI Wonder Stock” on the Verge of Blasting OffRight now, we’re witnessing a monumental shift in the world.Traders Agency | SponsoredBONUS GUIDE - Ben Stein Prepares For the Next Financial CrisisWith inflation high, debt soaring, and global tensions rising, a financial storm may be brewing. 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