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X4 Pharmaceuticals (XFOR) Competitors

X4 Pharmaceuticals logo
$2.85 -0.29 (-9.24%)
Closing price 08/15/2025 04:00 PM Eastern
Extended Trading
$2.82 -0.03 (-0.91%)
As of 08/15/2025 07:59 PM Eastern
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XFOR vs. XLO, KPTI, ENLV, SCYX, RANI, SNYR, CLSD, AKTX, ITRM, and MRSN

Should you be buying X4 Pharmaceuticals stock or one of its competitors? The main competitors of X4 Pharmaceuticals include Xilio Therapeutics (XLO), Karyopharm Therapeutics (KPTI), Enlivex Therapeutics (ENLV), SCYNEXIS (SCYX), Rani Therapeutics (RANI), Synergy CHC (SNYR), Clearside Biomedical (CLSD), Akari Therapeutics (AKTX), Iterum Therapeutics (ITRM), and Mersana Therapeutics (MRSN). These companies are all part of the "pharmaceutical products" industry.

X4 Pharmaceuticals vs. Its Competitors

Xilio Therapeutics (NASDAQ:XLO) and X4 Pharmaceuticals (NASDAQ:XFOR) are both small-cap medical companies, but which is the superior business? We will contrast the two businesses based on the strength of their institutional ownership, analyst recommendations, earnings, valuation, profitability, risk, dividends and media sentiment.

In the previous week, X4 Pharmaceuticals had 7 more articles in the media than Xilio Therapeutics. MarketBeat recorded 15 mentions for X4 Pharmaceuticals and 8 mentions for Xilio Therapeutics. X4 Pharmaceuticals' average media sentiment score of 0.39 beat Xilio Therapeutics' score of 0.19 indicating that X4 Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Xilio Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
4 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Neutral
X4 Pharmaceuticals
1 Very Positive mention(s)
1 Positive mention(s)
7 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral

X4 Pharmaceuticals has lower revenue, but higher earnings than Xilio Therapeutics. Xilio Therapeutics is trading at a lower price-to-earnings ratio than X4 Pharmaceuticals, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Xilio Therapeutics$6.34M5.79-$58.24M-$0.84-0.84
X4 Pharmaceuticals$2.56M6.45-$37.45M-$14.84-0.19

Xilio Therapeutics currently has a consensus target price of $3.00, indicating a potential upside of 323.13%. X4 Pharmaceuticals has a consensus target price of $71.17, indicating a potential upside of 2,397.08%. Given X4 Pharmaceuticals' higher probable upside, analysts plainly believe X4 Pharmaceuticals is more favorable than Xilio Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Xilio Therapeutics
0 Sell rating(s)
0 Hold rating(s)
2 Buy rating(s)
1 Strong Buy rating(s)
3.33
X4 Pharmaceuticals
0 Sell rating(s)
0 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
3.00

Xilio Therapeutics has a beta of -0.15, meaning that its stock price is 115% less volatile than the S&P 500. Comparatively, X4 Pharmaceuticals has a beta of 0.6, meaning that its stock price is 40% less volatile than the S&P 500.

X4 Pharmaceuticals has a net margin of -311.15% compared to Xilio Therapeutics' net margin of -374.79%. Xilio Therapeutics' return on equity of -342.32% beat X4 Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Xilio Therapeutics-374.79% -342.32% -67.61%
X4 Pharmaceuticals -311.15%-375.31%-72.87%

54.3% of Xilio Therapeutics shares are held by institutional investors. Comparatively, 72.0% of X4 Pharmaceuticals shares are held by institutional investors. 5.2% of Xilio Therapeutics shares are held by insiders. Comparatively, 2.4% of X4 Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

Summary

X4 Pharmaceuticals beats Xilio Therapeutics on 10 of the 17 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding XFOR and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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XFOR vs. The Competition

MetricX4 PharmaceuticalsMED IndustryMedical SectorNASDAQ Exchange
Market Cap$18.18M$3.10B$5.67B$9.82B
Dividend YieldN/A2.23%3.79%4.08%
P/E Ratio-0.1920.3830.5825.12
Price / Sales6.45368.96464.24116.42
Price / CashN/A42.3037.4059.05
Price / Book4.138.659.096.18
Net Income-$37.45M-$54.65M$3.25B$264.89M
7 Day Performance91.28%6.58%7.42%4.22%
1 Month Performance87.50%7.54%5.50%2.02%
1 Year Performance-86.33%13.73%30.67%24.22%

X4 Pharmaceuticals Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
XFOR
X4 Pharmaceuticals
4.3603 of 5 stars
$2.85
-9.2%
$71.17
+2,397.1%
-85.0%$18.18M$2.56M-0.1980News Coverage
Earnings Report
Analyst Forecast
Short Interest ↑
Analyst Revision
Gap Down
XLO
Xilio Therapeutics
2.8005 of 5 stars
$0.68
+2.6%
$3.00
+341.0%
-14.6%$34.33M$6.34M-0.8170News Coverage
Earnings Report
Analyst Downgrade
High Trading Volume
KPTI
Karyopharm Therapeutics
3.8538 of 5 stars
$3.77
-4.3%
$37.40
+892.0%
-52.7%$34.04M$145.24M-0.28380Earnings Report
Analyst Forecast
Analyst Revision
ENLV
Enlivex Therapeutics
3.3411 of 5 stars
$1.47
+2.8%
$10.00
+580.3%
+49.2%$33.82MN/A-2.2370News Coverage
Short Interest ↓
Gap Up
SCYX
SCYNEXIS
1.3671 of 5 stars
$0.88
+1.7%
N/A-51.5%$33.75M$3.75M-1.5760News Coverage
Earnings Report
RANI
Rani Therapeutics
3.1814 of 5 stars
$0.50
-5.3%
$7.33
+1,366.7%
-79.5%$33.37M$1.03M-0.55110Analyst Upgrade
Short Interest ↓
SNYR
Synergy CHC
4.5098 of 5 stars
$3.84
+8.5%
$10.00
+160.4%
N/A$32.55M$34.83M0.0040News Coverage
Earnings Report
CLSD
Clearside Biomedical
2.7918 of 5 stars
$0.40
-1.1%
$4.20
+942.2%
-59.9%$32M$1.66M-1.0930Earnings Report
Short Interest ↑
AKTX
Akari Therapeutics
3.0991 of 5 stars
$1.05
+6.1%
$5.00
+376.2%
-68.4%$31.85MN/A0.009Upcoming Earnings
High Trading Volume
ITRM
Iterum Therapeutics
2.4173 of 5 stars
$0.71
+0.5%
$9.00
+1,160.2%
-29.3%$31.75MN/A-0.8410
MRSN
Mersana Therapeutics
4.0895 of 5 stars
$5.97
-5.2%
$130.00
+2,077.6%
-80.8%$31.41M$40.50M-0.40150News Coverage
Earnings Report
Analyst Forecast
Short Interest ↓
Analyst Revision

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This page (NASDAQ:XFOR) was last updated on 8/16/2025 by MarketBeat.com Staff
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