Zymeworks (ZYME) Institutional Ownership $24.43 +0.50 (+2.09%) Closing price 05/18/2026 04:00 PM EasternExtended Trading$24.64 +0.21 (+0.86%) As of 06:12 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Ownership Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOwnershipSEC FilingsShort InterestTrendsBuy This Stock Institutional Ownership Changes (13F Filings) for Zymeworks (NASDAQ:ZYME)CurrentInstitutional OwnershipPercentage92.89%Number ofInstitutional Buyers(last 12 months)107TotalInstitutional Inflows(last 12 months)$292.39MNumber ofInstitutional Sellers(last 12 months)78TotalInstitutional Outflows(last 12 months)$262.83M Get ZYME Insider Trade Alerts Want to know when executives and insiders are buying or selling Zymeworks stock? 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Skip Chart & View Institutional Buying and Selling Data ZYME Institutional Buying and Selling by Quarter Zymeworks Major Shareholders & Ownership History ExportReporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails5/18/2026Amundi14,084$353K0.0%N/A0.019% 5/18/2026 Royal Bank of Canada47,360$1.19M0.0%-14.0%0.065% 5/18/2026 Rubric Capital Management LP7,000,000$175.28M1.9%+21.7%9.586% 5/16/2026 The Manufacturers Life Insurance Company 31,592$791K0.0%+81.2%0.043% 5/16/2026 Quantinno Capital Management LP39,640$993K0.0%+37.2%0.054% 5/16/2026 SummitTX Capital L.P.321,427$8.05M0.3%+43.3%0.440% 5/16/2026 Lazard Asset Management LLC10,602$265K0.0%-23.0%0.015% 5/15/2026 Granahan Investment Management LLC250,773$6.28M0.3%+11.7%0.343% 5/14/2026 Arrowstreet Capital Limited Partnership743,898$18.63M0.0%+6.3%1.019% 5/14/2026 State of Wyoming17,148$429K0.1%+57.7%0.023% Get the Latest News and Ratings for ZYME and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Zymeworks and its competitors with MarketBeat's FREE daily newsletter. 5/7/2026 Dimensional Fund Advisors LP1,139,135$28.52M0.0%-1.7%1.545% 5/6/2026 Allspring Global Investments Holdings LLC8,507$221K0.0%+10.4%0.012% 5/5/2026 Bank of New York Mellon Corp124,105$3.11M0.0%-3.1%0.168% 5/5/2026 Hillsdale Investment Management Inc.345,622$8.65M0.2%+45.3%0.469% 5/4/2026 Principal Financial Group Inc.78,547$1.97M0.0%N/A0.107% 4/30/2026 Hsbc Holdings PLC37,777$940K0.0%+111.4%0.051% 4/25/2026 Strs Ohio30,100$754K0.0%+13.2%0.041% 4/24/2026 Capricorn Fund Managers Ltd1,007,210$25.22M3.9%-1.5%1.366% 4/22/2026 Janney Montgomery Scott LLC11,487$288K0.0%+3.8%0.016% 4/22/2026 Pictet Asset Management Holding SA9,256$232K0.0%-87.4%0.013% 4/20/2026 Assenagon Asset Management S.A.727,986$18.23M0.0%+12.5%0.987% 4/16/2026 SG Americas Securities LLC10,429$261K0.0%-40.6%0.014% 3/20/2026 Hsbc Holdings PLC17,868$476K0.0%-52.5%0.024% 3/3/2026 Caitong International Asset Management Co. Ltd1,399$37K0.0%N/A0.002% 2/26/2026 Seven Fleet Capital Management LP20,600$542K0.4%N/A0.028% 2/19/2026 Invesco Ltd.257,580$6.78M0.0%+175.0%0.344% 2/18/2026 Mackenzie Financial Corp45,460$1.20M0.0%-19.4%0.061% 2/18/2026 XTX Topco Ltd93,469$2.46M0.1%N/A0.125% 2/18/2026 VARCOV Co.9,818$259K0.1%N/A0.013% 2/18/2026 Vestal Point Capital LP865,000$22.78M0.8%-51.0%1.156% 2/18/2026 Virtus Investment Advisers LLC10,441$275K0.1%+20.2%0.014% 2/18/2026 SummitTX Capital L.P.224,268$5.91M0.2%N/A0.300% 2/18/2026 Susquehanna Portfolio Strategies LLC99,795$2.63M0.0%+18.5%0.133% 2/18/2026 Tang Capital Management LLC34,631$912K0.0%-96.9%0.046% 2/18/2026 Tudor Investment Corp ET AL30,324$798K0.0%-19.3%0.041% 2/18/2026 Quadrature Capital Ltd23,017$606K0.0%N/A0.031% 2/18/2026 Opaleye Management Inc.108,929$2.87M0.4%+8.9%0.146% 2/18/2026 Perceptive Advisors LLC3,261,850$85.89M1.5%+56.0%4.359% 2/18/2026 Millennium Management LLC381,621$10.05M0.0%-65.5%0.510% 2/18/2026 Man Group plc75,318$1.98M0.0%-52.5%0.101% Louis Navellier: My #1 AI stock for 2026 (name & ticker inside) (Ad)Louis Navellier's Stock Grader system helped him flag Nvidia before its 82,000% run and has identified the top S&P 500 stock for 12 years running—and today, he's giving away his #1 AI stock pick for 2026, free. This company's sales are up 28% year over year, it holds over 30,000 patents in wireless and video technology, and it just earned an A-rating in his proprietary Stock Grader system that has cost him $9 million to build and maintain.Get the name and ticker of Louis Navellier's #1 AI stock free2/17/2026 Schonfeld Strategic Advisors LLC288,571$7.60M0.0%+167.7%0.386% 2/17/2026 AQR Capital Management LLC91,075$2.40M0.0%-40.3%0.122% 2/17/2026 Lazard Asset Management LLC13,776$363K0.0%-10.0%0.018% 2/17/2026 Trexquant Investment LP101,274$2.67M0.0%N/A0.135% 2/17/2026 Price T Rowe Associates Inc. MD28,784$758K0.0%+7.3%0.038% 2/17/2026 Vinva Investment Management Ltd12,216$322K0.0%-16.3%0.016% 2/17/2026 Adage Capital Partners GP L.L.C.663,546$17.47M0.0%+17.7%0.887% 2/17/2026California State Teachers Retirement System37,761$994K0.0%+7.2%0.050% 2/17/2026 Russell Investments Group Ltd.58,350$1.54M0.0%+1.6%0.078% 2/17/2026 Granahan Investment Management LLC224,408$5.91M0.3%-35.0%0.300% 2/17/2026 State of Wisconsin Investment Board75,566$1.99M0.0%+34.3%0.101% 2/17/2026 Royal Bank of Canada55,055$1.45M0.0%-5.0%0.074% 2/16/2026 Panagora Asset Management Inc.78,336$2.06M0.0%-26.1%0.105% 2/16/2026 Kennedy Capital Management LLC145,534$3.83M0.1%-0.6%0.194% 2/16/2026 Barclays PLC79,966$2.11M0.0%-59.8%0.107% 2/13/2026 Prosight Management LP530,393$13.97M2.9%-29.2%0.709% 2/13/2026 CreativeOne Wealth LLC18,264$481K0.0%N/A0.024% 2/13/2026 Rubric Capital Management LP5,750,000$151.40M1.8%+22.1%7.683% 2/13/2026 Stifel Financial Corp75,847$2.00M0.0%+4.6%0.101% 2/13/2026 Morgan Stanley2,593,080$68.28M0.0%-34.9%3.465% 2/13/2026 Schroder Investment Management Group97,907$2.60M0.0%-39.4%0.131% 2/13/2026 North Growth Management Ltd.45,000$1.18M0.2%-45.1%0.060% 2/13/2026 Siren L.L.C.1,680,121$44.24M1.3%N/A2.245% 2/13/2026 Charles Schwab Investment Management Inc.220,909$5.82M0.0%+14.2%0.295% 2/13/2026 Police & Firemen s Retirement System of New Jersey13,702$361K0.0%-3.5%0.018% 2/13/2026 State Street Corp1,037,642$27.32M0.0%-4.0%1.387% 2/13/2026 Caitong International Asset Management Co. Ltd2,073$55K0.2%N/A0.003% 2/13/2026 UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC320,261$8.43M0.0%-81.3%0.428% 2/13/2026 Wells Fargo & Company MN208,313$5.49M0.0%+17.9%0.278% 2/13/2026 Platinum Investment Management Ltd.105,184$2.77M0.6%-15.7%0.141% 2/12/2026 Northwest & Ethical Investments L.P.12,044$320K0.0%+20.1%0.016% 2/12/2026 Jane Street Group LLC70,445$1.86M0.0%-51.5%0.094% 2/12/2026 HRT Financial LP121,064$3.19M0.0%+76.8%0.162% 2/12/2026 Brooklyn Investment Group8,020$214K0.0%N/A0.011% 2/12/2026 MetLife Investment Management LLC28,630$754K0.0%-14.0%0.038% 2/12/2026 Commonwealth Equity Services LLC26,095$687K0.0%-16.5%0.035% 2/12/2026 Renaissance Technologies LLC220,877$5.82M0.0%-48.8%0.295% 2/12/2026 Dimensional Fund Advisors LP1,159,215$30.52M0.0%-2.7%1.549% 2/12/2026 Federated Hermes Inc.152,689$4.02M0.0%-16.5%0.204% 2/12/2026 New York State Common Retirement Fund17,371$457K0.0%+29.9%0.023% 2/12/2026 Campbell & CO Investment Adviser LLC33,588$884K0.0%+3.4%0.045% 2/12/2026 Bank of Montreal Can17,468$460K0.0%-36.8%0.023% 2/12/2026 Swiss National Bank74,200$1.95M0.0%+1.5%0.099% 2/12/2026 Nuveen LLC648,326$17.07M0.0%+14.7%0.866% 2/11/2026 Picton Mahoney Asset Management244,798$6.45M0.0%+18.6%0.327% 2/11/2026 Deutsche Bank AG1,595,833$42.02M0.0%+3.3%2.132% 2/11/2026 Franklin Resources Inc.58,987$1.55M0.0%+74.4%0.079% 2/11/2026 O Shaughnessy Asset Management LLC43,052$1.13M0.0%+3.1%0.058% 2/11/2026 WINTON GROUP Ltd11,180$294K0.0%N/A0.015% 2/11/2026 State of Wyoming10,875$286K0.0%N/A0.015% Louis Navellier: My #1 AI stock for 2026 (name & ticker inside) (Ad)Louis Navellier's Stock Grader system helped him flag Nvidia before its 82,000% run and has identified the top S&P 500 stock for 12 years running—and today, he's giving away his #1 AI stock pick for 2026, free. This company's sales are up 28% year over year, it holds over 30,000 patents in wireless and video technology, and it just earned an A-rating in his proprietary Stock Grader system that has cost him $9 million to build and maintain.Get the name and ticker of Louis Navellier's #1 AI stock free2/10/2026 Goldman Sachs Group Inc.420,207$11.06M0.0%-5.3%0.561% 2/10/2026 Hillsdale Investment Management Inc.237,922$6.26M0.2%+9.9%0.318% 2/10/2026 SBI Okasan Asset Management Co.Ltd.32,000$856K0.0%N/A0.043% 2/10/2026 Jupiter Asset Management Ltd.125,506$3.31M0.0%-64.2%0.168% 2/10/2026 Intech Investment Management LLC20,330$535K0.0%+19.7%0.027% 2/9/2026 Geode Capital Management LLC647,970$17.06M0.0%-4.5%0.866% 2/9/2026 Fisher Asset Management LLC68,197$1.80M0.0%-5.2%0.091% 2/6/2026 PSP Research LLC20,312$535K0.5%N/A0.027% 2/6/2026 ProShare Advisors LLC12,387$326K0.0%+10.6%0.017% 2/5/2026 Abacus Wealth Partners LLC10,222$269K0.0%N/A0.014% ZYME Institutional Ownership - Frequently Asked Questions Who are the largest shareholders of ZYME shares? During the previous two years, 190 institutional investors and hedge funds held shares of Zymeworks. The most heavily invested institutionals were EcoR1 Capital LLC ($288.28M), Rubric Capital Management LP ($175.28M), Perceptive Advisors LLC ($85.89M), Morgan Stanley ($68.28M), BVF Inc. IL ($63.08M), Vanguard Group Inc. ($61.32M), and Redmile Group LLC ($52.09M).Learn more on Zymeworks' institutional investors. What percentage of Zymeworks' stock is owned by institutional investors? 92.89% of Zymeworks' stock is owned by institutional investors. Learn more on ZYME's institutional investor holdings. Which institutional investors have been buying Zymeworks' stock? Of the 155 institutional investors that purchased Zymeworks' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: EcoR1 Capital LLC ($7.94M), Rubric Capital Management LP ($3.10M), UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC ($2.51M), Perceptive Advisors LLC ($1.76M), Vestal Point Capital LP ($1.76M), Siren L.L.C. ($1.68M), and Assenagon Asset Management S.A. ($1.56M). How much institutional buying is happening at Zymeworks? Institutional investors have bought a total of 21,156,165 shares in the last 24 months. This purchase volume represents approximately $292.39M in transactions. Which of Zymeworks' major shareholders have been selling company stock? Of the 78 institutional investors that sold Zymeworks' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: BNP PARIBAS ASSET MANAGEMENT Holding S.A. ($299.47M), UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC ($2.14M), Morgan Stanley ($1.39M), Tang Capital Management LLC ($1.07M), Vestal Point Capital LP ($900K), JPMorgan Chase & Co. ($815.61K), and Prosight Management LP ($779.51K). How much institutional selling is happening at Zymeworks? Institutional investors have sold a total of 312,633,729 shares in the last 24 months. This volume of shares sold represents approximately $262.83M in transactions. Related Companies Vaxcyte Major Shareholders Kymera Therapeutics Major Shareholders Qiagen Major Shareholders Rhythm Pharmaceuticals Major Shareholders TG Therapeutics Major Shareholders Protagonist Therapeutics Major Shareholders Spyre Therapeutics Major Shareholders Mirum Pharmaceuticals Major Shareholders Belite Bio Major Shareholders Terns Pharmaceuticals Major Shareholders This page (NASDAQ:ZYME) was last updated on 5/19/2026 by MarketBeat.com Staff. 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