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Zymeworks (ZYME) Institutional Ownership

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$24.10 +0.56 (+2.38%)
As of 09:59 AM Eastern
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Institutional Ownership Changes (13F Filings) for Zymeworks (NASDAQ:ZYME)

Current
Institutional Ownership
Percentage
92.89%
Number of
Institutional Buyers
(last 12 months)
107
Total
Institutional Inflows
(last 12 months)
$443.09M
Number of
Institutional Sellers
(last 12 months)
71
Total
Institutional Outflows
(last 12 months)
$262.83M
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ZYME Institutional Buying and Selling by Quarter

Zymeworks Major Shareholders & Ownership History

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Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
8/7/2026 BlackRock Inc.4,251,030$111.12M0.0%N/A5.822%
8/7/2026 Deutsche Bank AG397,190$10.38M0.0%N/A0.544%
8/7/2026 Persistent Asset Partners Ltd35,935$939K0.3%N/A0.049%
8/6/2026 Bank of New York Mellon Corp131,106$3.43M0.0%N/A0.180%
8/6/2026 State of Wyoming2,792$73K0.0%N/A0.004%
7/10/2026 Tema ETFs LLC105,615$2.76M0.1%+0.7%0.145%
7/8/2026 Assenagon Asset Management S.A.1,252,027$32.73M0.0%+72.0%1.715%
5/29/2026Perceptive Advisors LLC3,510,078$87.89M1.7%+7.6%4.807%
5/22/2026Segall Bryant & Hamill LLC45,726$1.15M0.0%N/A0.063%
5/19/2026Bank of America Corp DE236,754$5.93M0.0%+164.5%0.324%
5/18/2026Amundi14,084$353K0.0%N/A0.019%
5/18/2026Royal Bank of Canada47,360$1.19M0.0%-14.0%0.065%
5/18/2026Rubric Capital Management LP7,000,000$175.28M1.9%+21.7%9.586%
5/16/2026The Manufacturers Life Insurance Company 31,592$791K0.0%+81.2%0.043%
5/16/2026Quantinno Capital Management LP39,640$993K0.0%+37.2%0.054%
5/16/2026SummitTX Capital L.P.321,427$8.05M0.3%+43.3%0.440%
5/16/2026Lazard Asset Management LLC10,602$265K0.0%-23.0%0.015%
5/15/2026Granahan Investment Management LLC250,773$6.28M0.3%+11.7%0.343%
5/14/2026Arrowstreet Capital Limited Partnership743,898$18.63M0.0%+6.3%1.019%
5/14/2026 State of Wyoming17,148$429K0.1%+57.7%0.023%
5/7/2026Dimensional Fund Advisors LP1,139,135$28.52M0.0%-1.7%1.545%
5/6/2026Allspring Global Investments Holdings LLC8,507$221K0.0%+10.4%0.012%
5/5/2026 Bank of New York Mellon Corp124,105$3.11M0.0%-3.1%0.168%
5/5/2026Hillsdale Investment Management Inc.345,622$8.65M0.2%+45.3%0.469%
5/4/2026 Principal Financial Group Inc.78,547$1.97M0.0%N/A0.107%
4/30/2026Hsbc Holdings PLC37,777$940K0.0%+111.4%0.051%
4/25/2026 Strs Ohio30,100$754K0.0%+13.2%0.041%
4/24/2026 Capricorn Fund Managers Ltd1,007,210$25.22M3.9%-1.5%1.366%
4/22/2026 Janney Montgomery Scott LLC11,487$288K0.0%+3.8%0.016%
4/22/2026 Pictet Asset Management Holding SA9,256$232K0.0%-87.4%0.013%
4/20/2026 Assenagon Asset Management S.A.727,986$18.23M0.0%+12.5%0.987%
4/16/2026 SG Americas Securities LLC10,429$261K0.0%-40.6%0.014%
3/20/2026Hsbc Holdings PLC17,868$476K0.0%-52.5%0.024%
3/3/2026 Caitong International Asset Management Co. Ltd1,399$37K0.0%N/A0.002%
2/26/2026Seven Fleet Capital Management LP20,600$542K0.4%N/A0.028%
2/19/2026Invesco Ltd.257,580$6.78M0.0%+175.0%0.344%
2/18/2026Mackenzie Financial Corp45,460$1.20M0.0%-19.4%0.061%
2/18/2026XTX Topco Ltd93,469$2.46M0.1%N/A0.125%
2/18/2026VARCOV Co.9,818$259K0.1%N/A0.013%
2/18/2026Vestal Point Capital LP865,000$22.78M0.8%-51.0%1.156%
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2/18/2026Virtus Investment Advisers LLC10,441$275K0.1%+20.2%0.014%
2/18/2026SummitTX Capital L.P.224,268$5.91M0.2%N/A0.300%
2/18/2026Susquehanna Portfolio Strategies LLC99,795$2.63M0.0%+18.5%0.133%
2/18/2026Tang Capital Management LLC34,631$912K0.0%-96.9%0.046%
2/18/2026Tudor Investment Corp ET AL30,324$798K0.0%-19.3%0.041%
2/18/2026 Quadrature Capital Ltd23,017$606K0.0%N/A0.031%
2/18/2026Opaleye Management Inc.108,929$2.87M0.4%+8.9%0.146%
2/18/2026Perceptive Advisors LLC3,261,850$85.89M1.5%+56.0%4.359%
2/18/2026Millennium Management LLC381,621$10.05M0.0%-65.5%0.510%
2/18/2026Man Group plc75,318$1.98M0.0%-52.5%0.101%
2/17/2026Schonfeld Strategic Advisors LLC288,571$7.60M0.0%+167.7%0.386%
2/17/2026AQR Capital Management LLC91,075$2.40M0.0%-40.3%0.122%
2/17/2026Lazard Asset Management LLC13,776$363K0.0%-10.0%0.018%
2/17/2026Trexquant Investment LP101,274$2.67M0.0%N/A0.135%
2/17/2026Price T Rowe Associates Inc. MD28,784$758K0.0%+7.3%0.038%
2/17/2026Vinva Investment Management Ltd12,216$322K0.0%-16.3%0.016%
2/17/2026Adage Capital Partners GP L.L.C.663,546$17.47M0.0%+17.7%0.887%
2/17/2026California State Teachers Retirement System37,761$994K0.0%+7.2%0.050%
2/17/2026 Russell Investments Group Ltd.58,350$1.54M0.0%+1.6%0.078%
2/17/2026Granahan Investment Management LLC224,408$5.91M0.3%-35.0%0.300%
2/17/2026State of Wisconsin Investment Board75,566$1.99M0.0%+34.3%0.101%
2/17/2026Royal Bank of Canada55,055$1.45M0.0%-5.0%0.074%
2/16/2026 Panagora Asset Management Inc.78,336$2.06M0.0%-26.1%0.105%
2/16/2026Kennedy Capital Management LLC145,534$3.83M0.1%-0.6%0.194%
2/16/2026Barclays PLC79,966$2.11M0.0%-59.8%0.107%
2/13/2026Prosight Management LP530,393$13.97M2.9%-29.2%0.709%
2/13/2026CreativeOne Wealth LLC18,264$481K0.0%N/A0.024%
2/13/2026Rubric Capital Management LP5,750,000$151.40M1.8%+22.1%7.683%
2/13/2026Stifel Financial Corp75,847$2.00M0.0%+4.6%0.101%
2/13/2026Morgan Stanley2,593,080$68.28M0.0%-34.9%3.465%
2/13/2026Schroder Investment Management Group97,907$2.60M0.0%-39.4%0.131%
2/13/2026 North Growth Management Ltd.45,000$1.18M0.2%-45.1%0.060%
2/13/2026Siren L.L.C.1,680,121$44.24M1.3%N/A2.245%
2/13/2026Charles Schwab Investment Management Inc.220,909$5.82M0.0%+14.2%0.295%
2/13/2026 Police & Firemen s Retirement System of New Jersey13,702$361K0.0%-3.5%0.018%
2/13/2026 State Street Corp1,037,642$27.32M0.0%-4.0%1.387%
2/13/2026 Caitong International Asset Management Co. Ltd2,073$55K0.2%N/A0.003%
2/13/2026UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC320,261$8.43M0.0%-81.3%0.428%
2/13/2026Wells Fargo & Company MN208,313$5.49M0.0%+17.9%0.278%
2/13/2026Platinum Investment Management Ltd.105,184$2.77M0.6%-15.7%0.141%
2/12/2026Northwest & Ethical Investments L.P.12,044$320K0.0%+20.1%0.016%
2/12/2026Jane Street Group LLC70,445$1.86M0.0%-51.5%0.094%
2/12/2026HRT Financial LP121,064$3.19M0.0%+76.8%0.162%
2/12/2026Brooklyn Investment Group8,020$214K0.0%N/A0.011%
2/12/2026MetLife Investment Management LLC28,630$754K0.0%-14.0%0.038%
2/12/2026 Commonwealth Equity Services LLC26,095$687K0.0%-16.5%0.035%
2/12/2026Renaissance Technologies LLC220,877$5.82M0.0%-48.8%0.295%
2/12/2026Dimensional Fund Advisors LP1,159,215$30.52M0.0%-2.7%1.549%
2/12/2026Federated Hermes Inc.152,689$4.02M0.0%-16.5%0.204%
2/12/2026 New York State Common Retirement Fund17,371$457K0.0%+29.9%0.023%
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2/12/2026 Campbell & CO Investment Adviser LLC33,588$884K0.0%+3.4%0.045%
2/12/2026Bank of Montreal Can17,468$460K0.0%-36.8%0.023%
2/12/2026Swiss National Bank74,200$1.95M0.0%+1.5%0.099%
2/12/2026Nuveen LLC648,326$17.07M0.0%+14.7%0.866%
2/11/2026Picton Mahoney Asset Management244,798$6.45M0.0%+18.6%0.327%
2/11/2026 Deutsche Bank AG1,595,833$42.02M0.0%+3.3%2.132%
2/11/2026Franklin Resources Inc.58,987$1.55M0.0%+74.4%0.079%
2/11/2026O Shaughnessy Asset Management LLC43,052$1.13M0.0%+3.1%0.058%
2/11/2026 WINTON GROUP Ltd11,180$294K0.0%N/A0.015%
2/11/2026 State of Wyoming10,875$286K0.0%N/A0.015%


ZYME Institutional Ownership - Frequently Asked Questions

During the previous two years, 189 institutional investors and hedge funds held shares of Zymeworks. The most heavily invested institutionals were EcoR1 Capital LLC ($288.28M), Rubric Capital Management LP ($175.28M), BlackRock Inc. ($111.12M), Perceptive Advisors LLC ($87.89M), Morgan Stanley ($68.28M), BVF Inc. IL ($63.08M), and Vanguard Group Inc. ($61.32M).Learn more on Zymeworks' institutional investors.

92.89% of Zymeworks' stock is owned by institutional investors. Learn more on ZYME's institutional investor holdings.

Of the 151 institutional investors that purchased Zymeworks' stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: EcoR1 Capital LLC ($7.94M), BlackRock Inc. ($4.25M), Rubric Capital Management LP ($3.10M), UBS AM A Distinct Business Unit of UBS Asset Management Americas LLC ($2.51M), Assenagon Asset Management S.A. ($2.08M), Perceptive Advisors LLC ($2.01M), and Vestal Point Capital LP ($1.76M).

Institutional investors have bought a total of 26,849,499 shares in the last 24 months. This purchase volume represents approximately $443.09M in transactions.

Of the 71 institutional investors that sold Zymeworks' stock in the last 24 months, the following investors and hedge funds have sold the highest volume of shares: UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC ($2.14M), Morgan Stanley ($1.39M), Tang Capital Management LLC ($1.07M), Vestal Point Capital LP ($900K), JPMorgan Chase & Co. ($815.61K), Prosight Management LP ($779.51K), and Millennium Management LLC ($723.19K).

Institutional investors have sold a total of 12,948,037 shares in the last 24 months. This volume of shares sold represents approximately $262.83M in transactions.


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Institutional ownership data for NASDAQ:ZYME is compiled from quarterly 13F filings submitted to the U.S. Securities and Exchange Commission (SEC), with the most recent received on 8/7/2026. New 13F filings are added each quarter as they're published.
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