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Zymeworks (ZYME) Competitors

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$25.79 +0.53 (+2.10%)
Closing price 04:00 PM Eastern
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$25.79 0.00 (0.00%)
As of 07:30 PM Eastern
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ZYME vs. IONS, IMVT, ALKS, IOVA, and RYTM

Should you buy Zymeworks stock or one of its competitors? Zymeworks's main competitors and comparable companies include Ionis Pharmaceuticals (IONS), Immunovant (IMVT), Alkermes (ALKS), Iovance Biotherapeutics (IOVA), and Rhythm Pharmaceuticals (RYTM). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Zymeworks compare to Ionis Pharmaceuticals?

Ionis Pharmaceuticals (NASDAQ:IONS) and Zymeworks (NASDAQ:ZYME) are both healthcare companies, but which is the better stock? We will contrast the two businesses based on the strength of their valuation, analyst recommendations, earnings, media sentiment, dividends, profitability, risk and institutional ownership.

Ionis Pharmaceuticals has a beta of 0.38, meaning that its share price is 62% less volatile than the broader market. Comparatively, Zymeworks has a beta of 1.17, meaning that its share price is 17% more volatile than the broader market.

Ionis Pharmaceuticals presently has a consensus target price of $89.20, indicating a potential upside of 106.00%. Zymeworks has a consensus target price of $40.64, indicating a potential upside of 60.87%. Given Ionis Pharmaceuticals' higher possible upside, research analysts clearly believe Ionis Pharmaceuticals is more favorable than Zymeworks.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Ionis Pharmaceuticals
1 Sell rating(s)
4 Hold rating(s)
17 Buy rating(s)
0 Strong Buy rating(s)
2.73
Zymeworks
1 Sell rating(s)
1 Hold rating(s)
11 Buy rating(s)
0 Strong Buy rating(s)
2.77

Ionis Pharmaceuticals has a net margin of -64.76% compared to Zymeworks' net margin of -405.31%. Zymeworks' return on equity of -72.30% beat Ionis Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Ionis Pharmaceuticals-64.76% -111.08% -17.41%
Zymeworks -405.31%-72.30%-37.18%

In the previous week, Ionis Pharmaceuticals had 2 more articles in the media than Zymeworks. MarketBeat recorded 4 mentions for Ionis Pharmaceuticals and 2 mentions for Zymeworks. Zymeworks' average media sentiment score of 0.27 beat Ionis Pharmaceuticals' score of -0.42 indicating that Zymeworks is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Ionis Pharmaceuticals
0 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral
Zymeworks
0 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

93.9% of Ionis Pharmaceuticals shares are owned by institutional investors. Comparatively, 92.9% of Zymeworks shares are owned by institutional investors. 1.8% of Ionis Pharmaceuticals shares are owned by company insiders. Comparatively, 33.5% of Zymeworks shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Zymeworks has lower revenue, but higher earnings than Ionis Pharmaceuticals. Ionis Pharmaceuticals is trading at a lower price-to-earnings ratio than Zymeworks, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Ionis Pharmaceuticals$944M7.62-$381.39M-$3.46N/A
Zymeworks$37.13M48.28-$81.13M-$2.02N/A

Summary

Zymeworks beats Ionis Pharmaceuticals on 9 of the 16 factors compared between the two stocks.

How does Zymeworks compare to Immunovant?

Immunovant (NASDAQ:IMVT) and Zymeworks (NASDAQ:ZYME) are both healthcare companies, but which is the better investment? We will contrast the two companies based on the strength of their analyst recommendations, valuation, media sentiment, profitability, risk, dividends, earnings and institutional ownership.

47.1% of Immunovant shares are owned by institutional investors. Comparatively, 92.9% of Zymeworks shares are owned by institutional investors. 1.9% of Immunovant shares are owned by company insiders. Comparatively, 33.5% of Zymeworks shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock is poised for long-term growth.

In the previous week, Immunovant had 5 more articles in the media than Zymeworks. MarketBeat recorded 7 mentions for Immunovant and 2 mentions for Zymeworks. Immunovant's average media sentiment score of 0.69 beat Zymeworks' score of 0.27 indicating that Immunovant is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Immunovant
3 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Positive
Zymeworks
0 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Immunovant has a beta of 0.84, suggesting that its stock price is 16% less volatile than the broader market. Comparatively, Zymeworks has a beta of 1.17, suggesting that its stock price is 17% more volatile than the broader market.

Immunovant presently has a consensus price target of $44.00, indicating a potential upside of 45.41%. Zymeworks has a consensus price target of $40.64, indicating a potential upside of 60.87%. Given Zymeworks' stronger consensus rating and higher probable upside, analysts plainly believe Zymeworks is more favorable than Immunovant.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Immunovant
1 Sell rating(s)
3 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.58
Zymeworks
1 Sell rating(s)
1 Hold rating(s)
11 Buy rating(s)
0 Strong Buy rating(s)
2.77

Immunovant has a net margin of 0.00% compared to Zymeworks' net margin of -405.31%. Immunovant's return on equity of -69.59% beat Zymeworks' return on equity.

Company Net Margins Return on Equity Return on Assets
ImmunovantN/A -69.59% -62.49%
Zymeworks -405.31%-72.30%-37.18%

Zymeworks has higher revenue and earnings than Immunovant. Zymeworks is trading at a lower price-to-earnings ratio than Immunovant, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
ImmunovantN/AN/A-$505.61M-$2.82N/A
Zymeworks$37.13M48.28-$81.13M-$2.02N/A

Summary

Zymeworks beats Immunovant on 10 of the 15 factors compared between the two stocks.

How does Zymeworks compare to Alkermes?

Zymeworks (NASDAQ:ZYME) and Alkermes (NASDAQ:ALKS) are both healthcare companies, but which is the better business? We will compare the two companies based on the strength of their media sentiment, profitability, valuation, dividends, earnings, analyst recommendations, institutional ownership and risk.

Zymeworks has a beta of 1.17, indicating that its stock price is 17% more volatile than the broader market. Comparatively, Alkermes has a beta of 0.32, indicating that its stock price is 68% less volatile than the broader market.

Zymeworks currently has a consensus target price of $40.64, suggesting a potential upside of 60.87%. Alkermes has a consensus target price of $54.47, suggesting a potential upside of 35.80%. Given Zymeworks' stronger consensus rating and higher possible upside, analysts clearly believe Zymeworks is more favorable than Alkermes.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Zymeworks
1 Sell rating(s)
1 Hold rating(s)
11 Buy rating(s)
0 Strong Buy rating(s)
2.77
Alkermes
1 Sell rating(s)
5 Hold rating(s)
11 Buy rating(s)
2 Strong Buy rating(s)
2.74

In the previous week, Alkermes had 5 more articles in the media than Zymeworks. MarketBeat recorded 7 mentions for Alkermes and 2 mentions for Zymeworks. Alkermes' average media sentiment score of 0.52 beat Zymeworks' score of 0.27 indicating that Alkermes is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Zymeworks
0 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Alkermes
3 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Alkermes has higher revenue and earnings than Zymeworks. Zymeworks is trading at a lower price-to-earnings ratio than Alkermes, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Zymeworks$37.13M48.28-$81.13M-$2.02N/A
Alkermes$1.48B4.56$241.66M$0.38105.55

92.9% of Zymeworks shares are owned by institutional investors. Comparatively, 95.2% of Alkermes shares are owned by institutional investors. 33.5% of Zymeworks shares are owned by insiders. Comparatively, 4.6% of Alkermes shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company will outperform the market over the long term.

Alkermes has a net margin of 3.96% compared to Zymeworks' net margin of -405.31%. Alkermes' return on equity of 4.15% beat Zymeworks' return on equity.

Company Net Margins Return on Equity Return on Assets
Zymeworks-405.31% -72.30% -37.18%
Alkermes 3.96%4.15%2.19%

Summary

Alkermes beats Zymeworks on 11 of the 16 factors compared between the two stocks.

How does Zymeworks compare to Iovance Biotherapeutics?

Iovance Biotherapeutics (NASDAQ:IOVA) and Zymeworks (NASDAQ:ZYME) are both healthcare companies, but which is the superior investment? We will compare the two companies based on the strength of their valuation, risk, dividends, earnings, media sentiment, analyst recommendations, institutional ownership and profitability.

Iovance Biotherapeutics has a net margin of -89.11% compared to Zymeworks' net margin of -405.31%. Iovance Biotherapeutics' return on equity of -40.51% beat Zymeworks' return on equity.

Company Net Margins Return on Equity Return on Assets
Iovance Biotherapeutics-89.11% -40.51% -31.65%
Zymeworks -405.31%-72.30%-37.18%

In the previous week, Iovance Biotherapeutics had 18 more articles in the media than Zymeworks. MarketBeat recorded 20 mentions for Iovance Biotherapeutics and 2 mentions for Zymeworks. Iovance Biotherapeutics' average media sentiment score of 0.76 beat Zymeworks' score of 0.27 indicating that Iovance Biotherapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Iovance Biotherapeutics
4 Very Positive mention(s)
2 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Zymeworks
0 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Zymeworks has lower revenue, but higher earnings than Iovance Biotherapeutics. Iovance Biotherapeutics is trading at a lower price-to-earnings ratio than Zymeworks, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Iovance Biotherapeutics$324.97M18.55-$390.98M-$0.73N/A
Zymeworks$37.13M48.28-$81.13M-$2.02N/A

77.0% of Iovance Biotherapeutics shares are held by institutional investors. Comparatively, 92.9% of Zymeworks shares are held by institutional investors. 7.8% of Iovance Biotherapeutics shares are held by insiders. Comparatively, 33.5% of Zymeworks shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term.

Iovance Biotherapeutics has a beta of 0.76, suggesting that its stock price is 24% less volatile than the broader market. Comparatively, Zymeworks has a beta of 1.17, suggesting that its stock price is 17% more volatile than the broader market.

Iovance Biotherapeutics currently has a consensus target price of $12.90, suggesting a potential downside of 3.08%. Zymeworks has a consensus target price of $40.64, suggesting a potential upside of 60.87%. Given Zymeworks' stronger consensus rating and higher possible upside, analysts plainly believe Zymeworks is more favorable than Iovance Biotherapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Iovance Biotherapeutics
1 Sell rating(s)
3 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.62
Zymeworks
1 Sell rating(s)
1 Hold rating(s)
11 Buy rating(s)
0 Strong Buy rating(s)
2.77

Summary

Zymeworks beats Iovance Biotherapeutics on 9 of the 16 factors compared between the two stocks.

How does Zymeworks compare to Rhythm Pharmaceuticals?

Rhythm Pharmaceuticals (NASDAQ:RYTM) and Zymeworks (NASDAQ:ZYME) are both healthcare companies, but which is the better stock? We will contrast the two businesses based on the strength of their valuation, profitability, dividends, analyst recommendations, media sentiment, institutional ownership, earnings and risk.

Zymeworks has lower revenue, but higher earnings than Rhythm Pharmaceuticals. Rhythm Pharmaceuticals is trading at a lower price-to-earnings ratio than Zymeworks, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Rhythm Pharmaceuticals$239.92M25.61-$196.54M-$3.11N/A
Zymeworks$37.13M48.28-$81.13M-$2.02N/A

92.9% of Zymeworks shares are owned by institutional investors. 5.9% of Rhythm Pharmaceuticals shares are owned by company insiders. Comparatively, 33.5% of Zymeworks shares are owned by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

Rhythm Pharmaceuticals presently has a consensus price target of $140.89, suggesting a potential upside of 57.17%. Zymeworks has a consensus price target of $40.64, suggesting a potential upside of 60.87%. Given Zymeworks' stronger consensus rating and higher possible upside, analysts plainly believe Zymeworks is more favorable than Rhythm Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Rhythm Pharmaceuticals
1 Sell rating(s)
3 Hold rating(s)
17 Buy rating(s)
0 Strong Buy rating(s)
2.76
Zymeworks
1 Sell rating(s)
1 Hold rating(s)
11 Buy rating(s)
0 Strong Buy rating(s)
2.77

Rhythm Pharmaceuticals has a beta of 2.01, indicating that its share price is 101% more volatile than the broader market. Comparatively, Zymeworks has a beta of 1.17, indicating that its share price is 17% more volatile than the broader market.

In the previous week, Zymeworks had 2 more articles in the media than Rhythm Pharmaceuticals. MarketBeat recorded 2 mentions for Zymeworks and 0 mentions for Rhythm Pharmaceuticals. Zymeworks' average media sentiment score of 0.27 beat Rhythm Pharmaceuticals' score of 0.00 indicating that Zymeworks is being referred to more favorably in the news media.

Company Overall Sentiment
Rhythm Pharmaceuticals Neutral
Zymeworks Neutral

Rhythm Pharmaceuticals has a net margin of -85.59% compared to Zymeworks' net margin of -405.31%. Zymeworks' return on equity of -72.30% beat Rhythm Pharmaceuticals' return on equity.

Company Net Margins Return on Equity Return on Assets
Rhythm Pharmaceuticals-85.59% -159.87% -44.00%
Zymeworks -405.31%-72.30%-37.18%

Summary

Zymeworks beats Rhythm Pharmaceuticals on 12 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding ZYME and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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ZYME vs. The Competition

MetricZymeworksBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$1.79B$3.84B$7.16B$13.21B
Dividend YieldN/A3.66%2.53%20.71%
P/E Ratio-12.7713.42274.1326.16
Price / Sales17.271,212.26581.7894.37
Price / CashN/A116.5676.3853.09
Price / Book7.1817.1711.216.34
Net Income-$81.13M-$22.69M$3.50B$381.90M
7 Day Performance2.54%-1.20%-0.84%-1.39%
1 Month Performance-5.01%-9.68%-5.42%-4.31%
1 Year Performance52.42%10.09%4.38%-0.35%

Zymeworks Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
ZYME
Zymeworks
2.6825 of 5 stars
$25.79
+2.1%
$40.64
+57.6%
+51.4%$1.79B$105.96MN/A264
IONS
Ionis Pharmaceuticals
3.2032 of 5 stars
$43.54
-1.0%
$89.20
+104.9%
-38.1%$7.31B$944MN/A1,402
IMVT
Immunovant
2.5642 of 5 stars
$33.62
-0.1%
$44.00
+30.9%
+88.2%$6.94BN/AN/A315
ALKS
Alkermes
3.4642 of 5 stars
$41.75
+3.0%
$54.47
+30.5%
+27.3%$6.80B$1.48B109.872,050
IOVA
Iovance Biotherapeutics
2.3886 of 5 stars
$14.22
-0.1%
$12.40
-12.8%
+486.3%$6.45B$324.97MN/A975

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This page (NASDAQ:ZYME) was last updated on 10/9/2026 by MarketBeat.com Staff.
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