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Zymeworks (ZYME) Competitors

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$24.04 0.00 (0.00%)
Closing price 06/5/2026 04:00 PM Eastern
Extended Trading
$24.15 +0.11 (+0.46%)
As of 08:46 AM Eastern
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ZYME vs. PCVX, IMVT, KYMR, LNTH, and PTGX

Should you buy Zymeworks stock or one of its competitors? MarketBeat compares Zymeworks with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Zymeworks include Vaxcyte (PCVX), Immunovant (IMVT), Kymera Therapeutics (KYMR), Lantheus (LNTH), and Protagonist Therapeutics (PTGX). These companies are all part of the "pharmaceutical products" industry.

How does Zymeworks compare to Vaxcyte?

Zymeworks (NASDAQ:ZYME) and Vaxcyte (NASDAQ:PCVX) are both pharmaceutical products companies, but which is the better investment? We will compare the two businesses based on the strength of their media sentiment, dividends, risk, analyst recommendations, profitability, institutional ownership, valuation and earnings.

92.9% of Zymeworks shares are owned by institutional investors. Comparatively, 96.8% of Vaxcyte shares are owned by institutional investors. 33.5% of Zymeworks shares are owned by company insiders. Comparatively, 3.3% of Vaxcyte shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company is poised for long-term growth.

In the previous week, Vaxcyte had 4 more articles in the media than Zymeworks. MarketBeat recorded 6 mentions for Vaxcyte and 2 mentions for Zymeworks. Vaxcyte's average media sentiment score of 0.25 beat Zymeworks' score of 0.17 indicating that Vaxcyte is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Zymeworks
0 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Vaxcyte
3 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Zymeworks presently has a consensus price target of $38.00, indicating a potential upside of 58.07%. Vaxcyte has a consensus price target of $86.00, indicating a potential upside of 81.59%. Given Vaxcyte's higher possible upside, analysts plainly believe Vaxcyte is more favorable than Zymeworks.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Zymeworks
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
2 Strong Buy rating(s)
2.91
Vaxcyte
1 Sell rating(s)
1 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.63

Zymeworks has a beta of 1.15, meaning that its share price is 15% more volatile than the broader market. Comparatively, Vaxcyte has a beta of 1.24, meaning that its share price is 24% more volatile than the broader market.

Vaxcyte has a net margin of 0.00% compared to Zymeworks' net margin of -126.92%. Vaxcyte's return on equity of -32.51% beat Zymeworks' return on equity.

Company Net Margins Return on Equity Return on Assets
Zymeworks-126.92% -37.97% -25.31%
Vaxcyte N/A -32.51%-29.51%

Zymeworks has higher revenue and earnings than Vaxcyte. Zymeworks is trading at a lower price-to-earnings ratio than Vaxcyte, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Zymeworks$81.26M21.60-$81.13M-$1.37N/A
VaxcyteN/AN/A-$766.63M-$6.88N/A

Summary

Zymeworks and Vaxcyte tied by winning 8 of the 16 factors compared between the two stocks.

How does Zymeworks compare to Immunovant?

Immunovant (NASDAQ:IMVT) and Zymeworks (NASDAQ:ZYME) are both pharmaceutical products companies, but which is the superior investment? We will contrast the two companies based on the strength of their dividends, analyst recommendations, profitability, valuation, media sentiment, risk, institutional ownership and earnings.

47.1% of Immunovant shares are held by institutional investors. Comparatively, 92.9% of Zymeworks shares are held by institutional investors. 1.8% of Immunovant shares are held by insiders. Comparatively, 33.5% of Zymeworks shares are held by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock is poised for long-term growth.

Immunovant has a beta of 0.76, suggesting that its stock price is 24% less volatile than the broader market. Comparatively, Zymeworks has a beta of 1.15, suggesting that its stock price is 15% more volatile than the broader market.

Zymeworks has higher revenue and earnings than Immunovant. Zymeworks is trading at a lower price-to-earnings ratio than Immunovant, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
ImmunovantN/AN/A-$505.61M-$2.78N/A
Zymeworks$81.26M21.60-$81.13M-$1.37N/A

In the previous week, Immunovant and Immunovant both had 2 articles in the media. Immunovant's average media sentiment score of 1.19 beat Zymeworks' score of 0.17 indicating that Immunovant is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Immunovant
2 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Zymeworks
0 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Immunovant has a net margin of 0.00% compared to Zymeworks' net margin of -126.92%. Zymeworks' return on equity of -37.97% beat Immunovant's return on equity.

Company Net Margins Return on Equity Return on Assets
ImmunovantN/A -65.66% -59.88%
Zymeworks -126.92%-37.97%-25.31%

Immunovant currently has a consensus price target of $37.33, suggesting a potential upside of 20.00%. Zymeworks has a consensus price target of $38.00, suggesting a potential upside of 58.07%. Given Zymeworks' stronger consensus rating and higher possible upside, analysts plainly believe Zymeworks is more favorable than Immunovant.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Immunovant
1 Sell rating(s)
4 Hold rating(s)
6 Buy rating(s)
0 Strong Buy rating(s)
2.45
Zymeworks
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
2 Strong Buy rating(s)
2.91

Summary

Zymeworks beats Immunovant on 12 of the 15 factors compared between the two stocks.

How does Zymeworks compare to Kymera Therapeutics?

Zymeworks (NASDAQ:ZYME) and Kymera Therapeutics (NASDAQ:KYMR) are both pharmaceutical products companies, but which is the superior stock? We will compare the two businesses based on the strength of their profitability, risk, institutional ownership, valuation, media sentiment, earnings, analyst recommendations and dividends.

Zymeworks currently has a consensus price target of $38.00, indicating a potential upside of 58.07%. Kymera Therapeutics has a consensus price target of $118.10, indicating a potential upside of 59.31%. Given Kymera Therapeutics' stronger consensus rating and higher probable upside, analysts plainly believe Kymera Therapeutics is more favorable than Zymeworks.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Zymeworks
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
2 Strong Buy rating(s)
2.91
Kymera Therapeutics
1 Sell rating(s)
0 Hold rating(s)
20 Buy rating(s)
1 Strong Buy rating(s)
2.95

Zymeworks has higher revenue and earnings than Kymera Therapeutics. Kymera Therapeutics is trading at a lower price-to-earnings ratio than Zymeworks, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Zymeworks$81.26M21.60-$81.13M-$1.37N/A
Kymera Therapeutics$51.48M118.46-$311.35M-$3.57N/A

Zymeworks has a net margin of -126.92% compared to Kymera Therapeutics' net margin of -611.94%. Kymera Therapeutics' return on equity of -24.71% beat Zymeworks' return on equity.

Company Net Margins Return on Equity Return on Assets
Zymeworks-126.92% -37.97% -25.31%
Kymera Therapeutics -611.94%-24.71%-22.05%

92.9% of Zymeworks shares are held by institutional investors. 33.5% of Zymeworks shares are held by company insiders. Comparatively, 16.0% of Kymera Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

In the previous week, Kymera Therapeutics had 3 more articles in the media than Zymeworks. MarketBeat recorded 5 mentions for Kymera Therapeutics and 2 mentions for Zymeworks. Kymera Therapeutics' average media sentiment score of 1.18 beat Zymeworks' score of 0.17 indicating that Kymera Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Zymeworks
0 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Kymera Therapeutics
3 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Zymeworks has a beta of 1.15, meaning that its share price is 15% more volatile than the broader market. Comparatively, Kymera Therapeutics has a beta of 2.02, meaning that its share price is 102% more volatile than the broader market.

Summary

Kymera Therapeutics beats Zymeworks on 9 of the 17 factors compared between the two stocks.

How does Zymeworks compare to Lantheus?

Lantheus (NASDAQ:LNTH) and Zymeworks (NASDAQ:ZYME) are both pharmaceutical products companies, but which is the better stock? We will compare the two businesses based on the strength of their valuation, earnings, media sentiment, profitability, analyst recommendations, risk, institutional ownership and dividends.

In the previous week, Lantheus had 2 more articles in the media than Zymeworks. MarketBeat recorded 4 mentions for Lantheus and 2 mentions for Zymeworks. Lantheus' average media sentiment score of 0.54 beat Zymeworks' score of 0.17 indicating that Lantheus is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Lantheus
1 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Zymeworks
0 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Lantheus currently has a consensus target price of $101.86, suggesting a potential upside of 0.87%. Zymeworks has a consensus target price of $38.00, suggesting a potential upside of 58.07%. Given Zymeworks' stronger consensus rating and higher probable upside, analysts clearly believe Zymeworks is more favorable than Lantheus.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Lantheus
0 Sell rating(s)
3 Hold rating(s)
8 Buy rating(s)
0 Strong Buy rating(s)
2.73
Zymeworks
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
2 Strong Buy rating(s)
2.91

Lantheus has higher revenue and earnings than Zymeworks. Zymeworks is trading at a lower price-to-earnings ratio than Lantheus, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Lantheus$1.55B4.25$233.56M$4.1524.33
Zymeworks$81.26M21.60-$81.13M-$1.37N/A

Lantheus has a net margin of 18.05% compared to Zymeworks' net margin of -126.92%. Lantheus' return on equity of 29.32% beat Zymeworks' return on equity.

Company Net Margins Return on Equity Return on Assets
Lantheus18.05% 29.32% 15.00%
Zymeworks -126.92%-37.97%-25.31%

Lantheus has a beta of -0.03, suggesting that its stock price is 103% less volatile than the broader market. Comparatively, Zymeworks has a beta of 1.15, suggesting that its stock price is 15% more volatile than the broader market.

99.1% of Lantheus shares are held by institutional investors. Comparatively, 92.9% of Zymeworks shares are held by institutional investors. 1.7% of Lantheus shares are held by insiders. Comparatively, 33.5% of Zymeworks shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company will outperform the market over the long term.

Summary

Lantheus beats Zymeworks on 11 of the 17 factors compared between the two stocks.

How does Zymeworks compare to Protagonist Therapeutics?

Zymeworks (NASDAQ:ZYME) and Protagonist Therapeutics (NASDAQ:PTGX) are both pharmaceutical products companies, but which is the better stock? We will compare the two businesses based on the strength of their dividends, analyst recommendations, valuation, earnings, risk, institutional ownership, profitability and media sentiment.

92.9% of Zymeworks shares are owned by institutional investors. Comparatively, 98.6% of Protagonist Therapeutics shares are owned by institutional investors. 33.5% of Zymeworks shares are owned by company insiders. Comparatively, 5.2% of Protagonist Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock will outperform the market over the long term.

In the previous week, Protagonist Therapeutics had 2 more articles in the media than Zymeworks. MarketBeat recorded 4 mentions for Protagonist Therapeutics and 2 mentions for Zymeworks. Protagonist Therapeutics' average media sentiment score of 0.64 beat Zymeworks' score of 0.17 indicating that Protagonist Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Zymeworks
0 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Protagonist Therapeutics
2 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Zymeworks has higher revenue and earnings than Protagonist Therapeutics. Protagonist Therapeutics is trading at a lower price-to-earnings ratio than Zymeworks, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Zymeworks$81.26M21.60-$81.13M-$1.37N/A
Protagonist Therapeutics$74.06M84.56-$130.15M-$1.81N/A

Zymeworks presently has a consensus price target of $38.00, indicating a potential upside of 58.07%. Protagonist Therapeutics has a consensus price target of $115.21, indicating a potential upside of 18.31%. Given Zymeworks' stronger consensus rating and higher possible upside, equities analysts plainly believe Zymeworks is more favorable than Protagonist Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Zymeworks
1 Sell rating(s)
1 Hold rating(s)
7 Buy rating(s)
2 Strong Buy rating(s)
2.91
Protagonist Therapeutics
1 Sell rating(s)
1 Hold rating(s)
13 Buy rating(s)
1 Strong Buy rating(s)
2.88

Zymeworks has a net margin of -126.92% compared to Protagonist Therapeutics' net margin of -154.88%. Protagonist Therapeutics' return on equity of -17.76% beat Zymeworks' return on equity.

Company Net Margins Return on Equity Return on Assets
Zymeworks-126.92% -37.97% -25.31%
Protagonist Therapeutics -154.88%-17.76%-16.47%

Zymeworks has a beta of 1.15, suggesting that its stock price is 15% more volatile than the broader market. Comparatively, Protagonist Therapeutics has a beta of 1.85, suggesting that its stock price is 85% more volatile than the broader market.

Summary

Zymeworks beats Protagonist Therapeutics on 9 of the 17 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding ZYME and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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ZYME vs. The Competition

MetricZymeworksPharmaceutical Preparations IndustryManufacturing SectorNASDAQ Exchange
Market Cap$1.76B$989.71M$4.24B$11.98B
Dividend YieldN/A4.84%9.67%5.55%
P/E Ratio-17.551.4821.7523.62
Price / Sales21.60135.52222.2889.64
Price / CashN/A20.0646.5137.25
Price / Book6.707.8827.486.66
Net Income-$81.13M-$4.04M$119.60M$337.72M
7 Day Performance-2.04%-2.28%-3.66%-3.74%
1 Month Performance0.63%5.28%0.23%0.95%
1 Year PerformanceN/A106.41%11.93%25.35%

Zymeworks Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
ZYME
Zymeworks
2.5265 of 5 stars
$24.04
flat
$38.00
+58.1%
N/A$1.76B$81.26MN/A460
PCVX
Vaxcyte
2.8378 of 5 stars
$51.40
+0.7%
$86.00
+67.3%
+28.0%$7.37BN/AN/A160
IMVT
Immunovant
2.6541 of 5 stars
$33.30
-0.6%
$37.33
+12.1%
+85.5%$6.84BN/AN/A120
KYMR
Kymera Therapeutics
2.2766 of 5 stars
$81.42
0.0%
$118.10
+45.0%
+55.7%$6.70B$51.48MN/A170
LNTH
Lantheus
2.1422 of 5 stars
$99.30
-0.3%
$101.86
+2.6%
+23.8%$6.49B$1.54B23.931,193

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This page (NASDAQ:ZYME) was last updated on 6/8/2026 by MarketBeat.com Staff.
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