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Zymeworks (ZYME) Competitors

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$23.95 +0.41 (+1.75%)
As of 11:09 AM Eastern
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ZYME vs. CGON, PTCT, XENE, DNTH, and KNSA

Should you buy Zymeworks stock or one of its competitors? MarketBeat compares Zymeworks with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Zymeworks include CG Oncology (CGON), PTC Therapeutics (PTCT), Xenon Pharmaceuticals (XENE), Dianthus Therapeutics (DNTH), and Kiniksa Pharmaceuticals International (KNSA). These companies are all part of the "biotechnology" industry.

How does Zymeworks compare to CG Oncology?

Zymeworks (NASDAQ:ZYME) and CG Oncology (NASDAQ:CGON) are both healthcare companies, but which is the better business? We will compare the two companies based on the strength of their risk, institutional ownership, media sentiment, profitability, earnings, valuation, dividends and analyst recommendations.

Zymeworks has a net margin of -405.31% compared to CG Oncology's net margin of -3,602.68%. CG Oncology's return on equity of -26.58% beat Zymeworks' return on equity.

Company Net Margins Return on Equity Return on Assets
Zymeworks-405.31% -72.30% -37.18%
CG Oncology -3,602.68%-26.58%-25.34%

Zymeworks has higher revenue and earnings than CG Oncology. CG Oncology is trading at a lower price-to-earnings ratio than Zymeworks, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Zymeworks$105.96M16.04-$81.13M-$2.02N/A
CG Oncology$4.04M1,660.49-$160.99M-$2.69N/A

Zymeworks has a beta of 1.15, suggesting that its stock price is 15% more volatile than the broader market. Comparatively, CG Oncology has a beta of 0.23, suggesting that its stock price is 77% less volatile than the broader market.

92.9% of Zymeworks shares are owned by institutional investors. Comparatively, 26.6% of CG Oncology shares are owned by institutional investors. 33.5% of Zymeworks shares are owned by insiders. Comparatively, 4.8% of CG Oncology shares are owned by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

Zymeworks currently has a consensus price target of $38.22, indicating a potential upside of 59.59%. CG Oncology has a consensus price target of $83.18, indicating a potential upside of 9.91%. Given Zymeworks' stronger consensus rating and higher probable upside, equities analysts clearly believe Zymeworks is more favorable than CG Oncology.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Zymeworks
1 Sell rating(s)
1 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
2.82
CG Oncology
1 Sell rating(s)
2 Hold rating(s)
11 Buy rating(s)
0 Strong Buy rating(s)
2.71

In the previous week, CG Oncology had 13 more articles in the media than Zymeworks. MarketBeat recorded 29 mentions for CG Oncology and 16 mentions for Zymeworks. CG Oncology's average media sentiment score of 0.03 beat Zymeworks' score of -0.01 indicating that CG Oncology is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Zymeworks
5 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
2 Very Negative mention(s)
Neutral
CG Oncology
7 Very Positive mention(s)
1 Positive mention(s)
5 Neutral mention(s)
3 Negative mention(s)
1 Very Negative mention(s)
Neutral

Summary

Zymeworks beats CG Oncology on 11 of the 17 factors compared between the two stocks.

How does Zymeworks compare to PTC Therapeutics?

PTC Therapeutics (NASDAQ:PTCT) and Zymeworks (NASDAQ:ZYME) are both healthcare companies, but which is the better stock? We will contrast the two companies based on the strength of their institutional ownership, analyst recommendations, media sentiment, earnings, dividends, profitability, valuation and risk.

PTC Therapeutics has a beta of 0.56, meaning that its stock price is 44% less volatile than the broader market. Comparatively, Zymeworks has a beta of 1.15, meaning that its stock price is 15% more volatile than the broader market.

92.9% of Zymeworks shares are held by institutional investors. 5.3% of PTC Therapeutics shares are held by insiders. Comparatively, 33.5% of Zymeworks shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company is poised for long-term growth.

PTC Therapeutics has higher revenue and earnings than Zymeworks. PTC Therapeutics is trading at a lower price-to-earnings ratio than Zymeworks, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
PTC Therapeutics$1.73B3.58$682.64M-$0.58N/A
Zymeworks$105.96M16.04-$81.13M-$2.02N/A

In the previous week, Zymeworks had 7 more articles in the media than PTC Therapeutics. MarketBeat recorded 16 mentions for Zymeworks and 9 mentions for PTC Therapeutics. PTC Therapeutics' average media sentiment score of 0.47 beat Zymeworks' score of -0.01 indicating that PTC Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
PTC Therapeutics
4 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Zymeworks
5 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
2 Very Negative mention(s)
Neutral

PTC Therapeutics presently has a consensus price target of $98.09, indicating a potential upside of 32.22%. Zymeworks has a consensus price target of $38.22, indicating a potential upside of 59.59%. Given Zymeworks' stronger consensus rating and higher possible upside, analysts clearly believe Zymeworks is more favorable than PTC Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
PTC Therapeutics
2 Sell rating(s)
2 Hold rating(s)
9 Buy rating(s)
1 Strong Buy rating(s)
2.64
Zymeworks
1 Sell rating(s)
1 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
2.82

PTC Therapeutics has a net margin of -3.80% compared to Zymeworks' net margin of -405.31%. Zymeworks' return on equity of -72.30% beat PTC Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
PTC Therapeutics-3.80% -362.45% -1.32%
Zymeworks -405.31%-72.30%-37.18%

Summary

Zymeworks beats PTC Therapeutics on 9 of the 16 factors compared between the two stocks.

How does Zymeworks compare to Xenon Pharmaceuticals?

Zymeworks (NASDAQ:ZYME) and Xenon Pharmaceuticals (NASDAQ:XENE) are both healthcare companies, but which is the better investment? We will contrast the two businesses based on the strength of their profitability, valuation, dividends, institutional ownership, risk, earnings, analyst recommendations and media sentiment.

In the previous week, Zymeworks had 1 more articles in the media than Xenon Pharmaceuticals. MarketBeat recorded 16 mentions for Zymeworks and 15 mentions for Xenon Pharmaceuticals. Xenon Pharmaceuticals' average media sentiment score of 0.65 beat Zymeworks' score of -0.01 indicating that Xenon Pharmaceuticals is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Zymeworks
5 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
2 Very Negative mention(s)
Neutral
Xenon Pharmaceuticals
5 Very Positive mention(s)
0 Positive mention(s)
7 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Zymeworks has higher revenue and earnings than Xenon Pharmaceuticals. Xenon Pharmaceuticals is trading at a lower price-to-earnings ratio than Zymeworks, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Zymeworks$105.96M16.04-$81.13M-$2.02N/A
Xenon Pharmaceuticals$7.50M816.63-$345.91M-$4.74N/A

Zymeworks presently has a consensus price target of $38.22, indicating a potential upside of 59.59%. Xenon Pharmaceuticals has a consensus price target of $77.13, indicating a potential upside of 21.74%. Given Zymeworks' higher probable upside, equities analysts clearly believe Zymeworks is more favorable than Xenon Pharmaceuticals.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Zymeworks
1 Sell rating(s)
1 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
2.82
Xenon Pharmaceuticals
1 Sell rating(s)
0 Hold rating(s)
14 Buy rating(s)
2 Strong Buy rating(s)
3.00

Xenon Pharmaceuticals has a net margin of 0.00% compared to Zymeworks' net margin of -405.31%. Xenon Pharmaceuticals' return on equity of -43.98% beat Zymeworks' return on equity.

Company Net Margins Return on Equity Return on Assets
Zymeworks-405.31% -72.30% -37.18%
Xenon Pharmaceuticals N/A -43.98%-41.72%

92.9% of Zymeworks shares are held by institutional investors. Comparatively, 95.5% of Xenon Pharmaceuticals shares are held by institutional investors. 33.5% of Zymeworks shares are held by insiders. Comparatively, 2.9% of Xenon Pharmaceuticals shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.

Zymeworks has a beta of 1.15, meaning that its share price is 15% more volatile than the broader market. Comparatively, Xenon Pharmaceuticals has a beta of 0.62, meaning that its share price is 38% less volatile than the broader market.

Summary

Zymeworks beats Xenon Pharmaceuticals on 9 of the 17 factors compared between the two stocks.

How does Zymeworks compare to Dianthus Therapeutics?

Zymeworks (NASDAQ:ZYME) and Dianthus Therapeutics (NASDAQ:DNTH) are both healthcare companies, but which is the better investment? We will compare the two companies based on the strength of their risk, dividends, earnings, profitability, valuation, analyst recommendations, media sentiment and institutional ownership.

Zymeworks has a beta of 1.15, suggesting that its stock price is 15% more volatile than the broader market. Comparatively, Dianthus Therapeutics has a beta of 1.22, suggesting that its stock price is 22% more volatile than the broader market.

In the previous week, Dianthus Therapeutics had 19 more articles in the media than Zymeworks. MarketBeat recorded 35 mentions for Dianthus Therapeutics and 16 mentions for Zymeworks. Dianthus Therapeutics' average media sentiment score of 0.54 beat Zymeworks' score of -0.01 indicating that Dianthus Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Zymeworks
5 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
2 Very Negative mention(s)
Neutral
Dianthus Therapeutics
10 Very Positive mention(s)
2 Positive mention(s)
6 Neutral mention(s)
0 Negative mention(s)
1 Very Negative mention(s)
Positive

92.9% of Zymeworks shares are owned by institutional investors. Comparatively, 47.5% of Dianthus Therapeutics shares are owned by institutional investors. 33.5% of Zymeworks shares are owned by insiders. Comparatively, 3.0% of Dianthus Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term.

Zymeworks currently has a consensus target price of $38.22, suggesting a potential upside of 59.59%. Dianthus Therapeutics has a consensus target price of $124.27, suggesting a potential upside of 13.26%. Given Zymeworks' higher probable upside, equities analysts clearly believe Zymeworks is more favorable than Dianthus Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Zymeworks
1 Sell rating(s)
1 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
2.82
Dianthus Therapeutics
1 Sell rating(s)
0 Hold rating(s)
12 Buy rating(s)
1 Strong Buy rating(s)
2.93

Zymeworks has a net margin of -405.31% compared to Dianthus Therapeutics' net margin of -10,096.95%. Dianthus Therapeutics' return on equity of -22.53% beat Zymeworks' return on equity.

Company Net Margins Return on Equity Return on Assets
Zymeworks-405.31% -72.30% -37.18%
Dianthus Therapeutics -10,096.95%-22.53%-21.55%

Zymeworks has higher revenue and earnings than Dianthus Therapeutics. Dianthus Therapeutics is trading at a lower price-to-earnings ratio than Zymeworks, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Zymeworks$105.96M16.04-$81.13M-$2.02N/A
Dianthus Therapeutics$2.04M2,940.52-$162.34M-$4.15N/A

Summary

Zymeworks and Dianthus Therapeutics tied by winning 8 of the 16 factors compared between the two stocks.

How does Zymeworks compare to Kiniksa Pharmaceuticals International?

Zymeworks (NASDAQ:ZYME) and Kiniksa Pharmaceuticals International (NASDAQ:KNSA) are both healthcare companies, but which is the superior business? We will contrast the two businesses based on the strength of their analyst recommendations, earnings, institutional ownership, media sentiment, valuation, dividends, risk and profitability.

Kiniksa Pharmaceuticals International has higher revenue and earnings than Zymeworks. Zymeworks is trading at a lower price-to-earnings ratio than Kiniksa Pharmaceuticals International, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Zymeworks$105.96M16.04-$81.13M-$2.02N/A
Kiniksa Pharmaceuticals International$677.56M8.86$59.01M$0.9779.34

Zymeworks has a beta of 1.15, indicating that its stock price is 15% more volatile than the broader market. Comparatively, Kiniksa Pharmaceuticals International has a beta of 0.05, indicating that its stock price is 95% less volatile than the broader market.

92.9% of Zymeworks shares are owned by institutional investors. Comparatively, 54.0% of Kiniksa Pharmaceuticals International shares are owned by institutional investors. 33.5% of Zymeworks shares are owned by insiders. Comparatively, 52.0% of Kiniksa Pharmaceuticals International shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company is poised for long-term growth.

In the previous week, Zymeworks had 9 more articles in the media than Kiniksa Pharmaceuticals International. MarketBeat recorded 16 mentions for Zymeworks and 7 mentions for Kiniksa Pharmaceuticals International. Kiniksa Pharmaceuticals International's average media sentiment score of 1.36 beat Zymeworks' score of -0.01 indicating that Kiniksa Pharmaceuticals International is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Zymeworks
5 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
2 Very Negative mention(s)
Neutral
Kiniksa Pharmaceuticals International
6 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
1 Negative mention(s)
0 Very Negative mention(s)
Positive

Zymeworks currently has a consensus target price of $38.22, suggesting a potential upside of 59.59%. Kiniksa Pharmaceuticals International has a consensus target price of $87.38, suggesting a potential upside of 13.54%. Given Zymeworks' higher possible upside, equities research analysts plainly believe Zymeworks is more favorable than Kiniksa Pharmaceuticals International.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Zymeworks
1 Sell rating(s)
1 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
2.82
Kiniksa Pharmaceuticals International
0 Sell rating(s)
1 Hold rating(s)
9 Buy rating(s)
0 Strong Buy rating(s)
2.90

Kiniksa Pharmaceuticals International has a net margin of 9.59% compared to Zymeworks' net margin of -405.31%. Kiniksa Pharmaceuticals International's return on equity of 13.65% beat Zymeworks' return on equity.

Company Net Margins Return on Equity Return on Assets
Zymeworks-405.31% -72.30% -37.18%
Kiniksa Pharmaceuticals International 9.59%13.65%10.09%

Summary

Kiniksa Pharmaceuticals International beats Zymeworks on 11 of the 17 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding ZYME and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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ZYME vs. The Competition

MetricZymeworksBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$1.70B$3.71B$7.03B$12.96B
Dividend YieldN/A3.76%2.58%10.20%
P/E Ratio-11.879.06269.9124.87
Price / Sales16.041,278.42654.69108.21
Price / CashN/A44.9528.8937.44
Price / Book6.6717.9711.406.45
Net Income-$81.13M-$13.25M$3.45B$347.50M
7 Day Performance9.82%5.58%3.66%3.77%
1 Month Performance-7.45%-1.60%-0.49%-0.40%
1 Year Performance99.26%61.32%77.51%23.55%

Zymeworks Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
ZYME
Zymeworks
2.862 of 5 stars
$23.95
+1.7%
$38.22
+59.6%
+95.8%$1.70B$105.96MN/A460
CGON
CG Oncology
2.2491 of 5 stars
$71.19
-2.5%
$81.73
+14.8%
+202.2%$6.44B$4.04MN/A61
PTCT
PTC Therapeutics
4.134 of 5 stars
$68.01
-9.9%
$95.75
+40.8%
+61.5%$6.26B$1.73BN/A1,410
XENE
Xenon Pharmaceuticals
2.7364 of 5 stars
$62.67
-2.4%
$77.20
+23.2%
+89.5%$6.20B$7.50MN/A210
DNTH
Dianthus Therapeutics
2.1078 of 5 stars
$106.92
-5.1%
$117.82
+10.2%
+480.6%$6.16B$2.04MN/A80

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This page (NASDAQ:ZYME) was last updated on 8/10/2026 by MarketBeat.com Staff.
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