Zymeworks (ZYME) Competitors $11.94 -0.49 (-3.94%) Closing price 04:00 PM EasternExtended Trading$11.94 0.00 (0.00%) As of 06:53 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsTrendsBuy This Stock ZYME vs. RARE, AKRO, ACLX, ZLAB, VKTX, CRNX, ALVO, SRRK, MRUS, and ACADShould you be buying Zymeworks stock or one of its competitors? The main competitors of Zymeworks include Ultragenyx Pharmaceutical (RARE), Akero Therapeutics (AKRO), Arcellx (ACLX), Zai Lab (ZLAB), Viking Therapeutics (VKTX), Crinetics Pharmaceuticals (CRNX), Alvotech (ALVO), Scholar Rock (SRRK), Merus (MRUS), and ACADIA Pharmaceuticals (ACAD). These companies are all part of the "pharmaceutical products" industry. Zymeworks vs. Ultragenyx Pharmaceutical Akero Therapeutics Arcellx Zai Lab Viking Therapeutics Crinetics Pharmaceuticals Alvotech Scholar Rock Merus ACADIA Pharmaceuticals Zymeworks (NYSE:ZYME) and Ultragenyx Pharmaceutical (NASDAQ:RARE) are both medical companies, but which is the superior business? We will contrast the two companies based on the strength of their analyst recommendations, valuation, earnings, profitability, media sentiment, institutional ownership, risk, community ranking and dividends. Is ZYME or RARE more profitable? Ultragenyx Pharmaceutical has a net margin of -101.60% compared to Zymeworks' net margin of -182.75%. Zymeworks' return on equity of -23.00% beat Ultragenyx Pharmaceutical's return on equity.Company Net Margins Return on Equity Return on Assets Zymeworks-182.75% -23.00% -18.04% Ultragenyx Pharmaceutical -101.60%-193.80%-38.15% Which has more volatility and risk, ZYME or RARE? Zymeworks has a beta of 1.24, meaning that its share price is 24% more volatile than the S&P 500. Comparatively, Ultragenyx Pharmaceutical has a beta of 0.34, meaning that its share price is 66% less volatile than the S&P 500. Do insiders & institutionals have more ownership in ZYME or RARE? 92.9% of Zymeworks shares are held by institutional investors. Comparatively, 97.7% of Ultragenyx Pharmaceutical shares are held by institutional investors. 1.9% of Zymeworks shares are held by company insiders. Comparatively, 5.5% of Ultragenyx Pharmaceutical shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock is poised for long-term growth. Do analysts rate ZYME or RARE? Zymeworks presently has a consensus price target of $21.00, suggesting a potential upside of 75.88%. Ultragenyx Pharmaceutical has a consensus price target of $90.93, suggesting a potential upside of 156.80%. Given Ultragenyx Pharmaceutical's stronger consensus rating and higher probable upside, analysts clearly believe Ultragenyx Pharmaceutical is more favorable than Zymeworks.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Zymeworks 0 Sell rating(s) 2 Hold rating(s) 7 Buy rating(s) 1 Strong Buy rating(s) 2.90Ultragenyx Pharmaceutical 0 Sell rating(s) 1 Hold rating(s) 14 Buy rating(s) 0 Strong Buy rating(s) 2.93 Which has better earnings and valuation, ZYME or RARE? Zymeworks has higher earnings, but lower revenue than Ultragenyx Pharmaceutical. Zymeworks is trading at a lower price-to-earnings ratio than Ultragenyx Pharmaceutical, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioZymeworks$93.38M8.90-$118.67M-$1.49-8.01Ultragenyx Pharmaceutical$590.69M5.67-$569.18M-$5.88-6.02 Does the MarketBeat Community believe in ZYME or RARE? Ultragenyx Pharmaceutical received 543 more outperform votes than Zymeworks when rated by MarketBeat users. Likewise, 77.54% of users gave Ultragenyx Pharmaceutical an outperform vote while only 67.89% of users gave Zymeworks an outperform vote. CompanyUnderperformOutperformZymeworksOutperform Votes29667.89% Underperform Votes14032.11% Ultragenyx PharmaceuticalOutperform Votes83977.54% Underperform Votes24322.46% Does the media refer more to ZYME or RARE? In the previous week, Zymeworks and Zymeworks both had 16 articles in the media. Ultragenyx Pharmaceutical's average media sentiment score of 1.34 beat Zymeworks' score of 1.04 indicating that Ultragenyx Pharmaceutical is being referred to more favorably in the news media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Zymeworks 7 Very Positive mention(s) 1 Positive mention(s) 3 Neutral mention(s) 0 Negative mention(s) 1 Very Negative mention(s) Positive Ultragenyx Pharmaceutical 15 Very Positive mention(s) 0 Positive mention(s) 1 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive SummaryUltragenyx Pharmaceutical beats Zymeworks on 11 of the 18 factors compared between the two stocks. Get Zymeworks News Delivered to You Automatically Sign up to receive the latest news and ratings for ZYME and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding {thisCompany.Symbol} and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NYSE and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart ZYME vs. The Competition Export to ExcelMetricZymeworksPharmaceutical IndustryMedical SectorNYSE ExchangeMarket Cap$830.75M$6.48B$5.35B$19.38BDividend YieldN/A2.66%5.22%3.84%P/E Ratio-7.968.9226.8434.23Price / Sales8.90250.95391.3934.85Price / CashN/A65.8538.2517.51Price / Book1.806.466.794.69Net Income-$118.67M$143.98M$3.23B$1.02B7 Day Performance6.13%3.04%4.07%-1.34%1 Month Performance1.62%7.44%12.52%9.79%1 Year Performance34.01%-2.46%16.83%3.27% Zymeworks Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)ZYMEZymeworks3.5197 of 5 stars$11.94-3.9%$21.00+75.9%+38.4%$830.75M$93.38M-7.96460News CoveragePositive NewsAnalyst ForecastInsider TradeRAREUltragenyx Pharmaceutical3.9527 of 5 stars$36.09+2.8%$90.93+152.0%-10.1%$3.32B$590.69M-5.691,310Positive NewsAKROAkero Therapeutics3.8261 of 5 stars$41.53+4.2%$76.29+83.7%+136.2%$3.31BN/A-11.0730Insider TradeHigh Trading VolumeACLXArcellx1.7682 of 5 stars$59.50+3.4%$109.31+83.7%+11.4%$3.28B$76.81M-83.8080News CoverageGap UpZLABZai Lab2.6348 of 5 stars$29.40+0.5%$47.37+61.1%+56.6%$3.24B$418.33M-10.611,950VKTXViking Therapeutics4.4189 of 5 stars$28.30+2.7%$87.15+208.0%-57.5%$3.18BN/A-28.3020Positive NewsCRNXCrinetics Pharmaceuticals3.6589 of 5 stars$33.32+8.6%$73.00+119.1%-38.0%$3.12B$1.04M-8.93210Gap UpALVOAlvotech1.752 of 5 stars$10.25+5.9%$18.00+75.6%-27.6%$3.09B$489.68M-5.544High Trading VolumeSRRKScholar Rock3.885 of 5 stars$32.46+5.8%$42.67+31.4%+151.9%$3.08B$33.19M-13.81140Positive NewsEarnings ReportAnalyst RevisionGap UpMRUSMerus3.2157 of 5 stars$42.41+3.7%$85.15+100.8%+0.9%$2.94B$36.13M-10.7437Earnings ReportAnalyst ForecastGap UpACADACADIA Pharmaceuticals3.2836 of 5 stars$17.52+0.5%$24.70+41.0%+43.6%$2.92B$996.28M22.46510Trending NewsAnalyst ForecastAnalyst RevisionGap Up Related Companies and Tools Related Companies RARE Alternatives AKRO Alternatives ACLX Alternatives ZLAB Alternatives VKTX Alternatives CRNX Alternatives ALVO Alternatives SRRK Alternatives MRUS Alternatives ACAD Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NYSE:ZYME) was last updated on 5/21/2025 by MarketBeat.com Staff From Our PartnersMarket Panic: Trump Just Dropped a Bomb on Your Stockstock Market Panic: Trump Just Dropped a Bomb on Your Stocks The market is in freefall—and Trump's new tarif...American Alternative | SponsoredGold Hits New Highs as Global Markets SpiralWhen Trump took office in 2017, gold was just $1,100 an ounce. By the time he left, it had soared to $1,839. ...Premier Gold Co | SponsoredWhite House to reset Social Security?Elon Musk's parting DOGE gift looks set to shock America... A single announcement by July 22nd could soon b...Altimetry | SponsoredThe Trump Dump is starting; Get out of stocks now?The first 365 days of the Trump presidency… Will be the best time to get rich in American history.Paradigm Press | SponsoredTrump’s treachery Trump’s Final Reset Inside the shocking plot to re-engineer America’s financial system…and why you need to ...Porter & Company | SponsoredBuffett’s favorite chart just hit 209% – here’s what that means for goldA Historic Gold Announcement Is About to Rock Wall Street For months, sharp-eyed analysts have watched the ...Golden Portfolio | SponsoredEveryone’s watching Nvidia right now. Here’s why I’m excited.So, unless you’ve been living under a rock, you probably saw the news… Nvidia just signed a $7 BILLION deal...Timothy Sykes | SponsoredIs President Trump Lying To You With This?President Trump’s economic transition isn’t without hardship. But what if there were a smart, tax-free way to ...Colonial Metals | Sponsored Adding Choose a watchlist: Watchlist Adding You have already added five stocks to your watchlist. Upgrade to MarketBeat All Access to add more stocks to your watchlist. Adding Zymeworks Inc. Please log in to your account or sign up in order to add this asset to your watchlist. Share Zymeworks With A Colleague Link copied to clipboard. Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. Start Your 30-Day Trial MarketBeat All Access Features Best-in-Class Portfolio Monitoring Get personalized stock ideas. Compare portfolio to indices. Check stock news, ratings, SEC filings, and more. Stock Ideas and Recommendations See daily stock ideas from top analysts. Receive short-term trading ideas from MarketBeat. Identify trending stocks on social media. Advanced Stock Screeners and Research Tools Use our seven stock screeners to find suitable stocks. Stay informed with MarketBeat's real-time news. Export data to Excel for personal analysis. Sign in to your free account to enjoy these benefits In-depth profiles and analysis for 20,000 public companies. Real-time analyst ratings, insider transactions, earnings data, and more. Our daily ratings and market update email newsletter. Sign in to your free account to enjoy all that MarketBeat has to offer. Sign In Create Account Your Email Address: Email Address Required Your Password: Password Required Log In or Sign in with Facebook Sign in with Google Forgot your password? Your Email Address: Please enter your email address. Please enter a valid email address Choose a Password: Please enter your password. Your password must be at least 8 characters long and contain at least 1 number, 1 letter, and 1 special character. Create My Account (Free) or Sign in with Facebook Sign in with Google By creating a free account, you agree to our terms of service. This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.