ALPS Medical Breakthroughs ETF (SBIO) Holdings $39.96 +0.11 (+0.28%) Closing price 04:10 PM EasternExtended Trading$39.93 -0.03 (-0.08%) As of 04:10 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Holdings Stock AnalysisChartHoldingsOwnershipRatingsShort InterestBuy This Stock Top 25 SBIO HoldingsRankCompanyCurrent PriceWeightShares Held1RYTMRhythm Pharmaceuticals$97.46-1.6%3.61%33,3482RNAAvidity Biosciences$46.15-1.8%3.34%71,3173AXSMAxsome Therapeutics$120.09-0.2%3.15%24,6954CYTKCytokinetics$59.99+5.3%3.15%57,2165MTSRMetsera$52.65+1.4%2.88%50,4696NUVLNuvalent$85.04+1.0%2.77%31,2127MRUSMerus$94.23-0.1%2.68%35,6688KRYSKrystal Biotech$183.290.0%2.47%13,5089CRNXCrinetics Pharmaceuticals$42.10+3.0%2.40%47,91510PTCTPTC Therapeutics$65.04-0.5%2.40%37,262 Get the Latest News and Ratings for SBIO and Related StocksEnter your email address below to receive the latest news and analysts' ratings for ALPS Medical Breakthroughs ETF and its competitors with MarketBeat's FREE daily newsletter. 11ALKSAlkermes$31.02-0.1%2.39%78,65212ARWRArrowhead Pharmaceuticals$37.57+4.0%2.36%65,89113PCVXVaxcyte$42.06-1.4%2.28%61,60714ACLXArcellx$84.10-1.1%2.21%25,45315PTGXProtagonist Therapeutics$64.72-0.2%2.17%29,51116MLTXMoonLake Immunotherapeutics$8.71+3.3%2.10%31,08017AKROAkero Therapeutics$45.45-1.4%1.97%37,75018MIRMMirum Pharmaceuticals$72.38-0.8%1.93%24,27619ACADACADIA Pharmaceuticals$21.65-0.7%1.87%81,34520ZLABZai Lab$33.66-0.3%1.83%53,17121NAMSNewAmsterdam Pharma$32.65+6.4%1.74%55,84422XENEXenon Pharmaceuticals$38.96-1.6%1.56%37,69323APLSApellis Pharmaceuticals$24.19+1.6%1.55%63,47724CGONCG Oncology$38.50-3.3%1.55%37,90925VKTXViking Therapeutics$31.66+6.5%1.55%55,412 Geographic ExposureUnited States86.6%Netherlands5.9%Ireland2.8%Canada2.3%Cayman Islands0.6%Israel0.4%Currency ExposureUSD100.0%Sector ExposureHealth Care98.0%Consumer Discretionary1.6%Energy0.3%Industry ExposureBiotechnology89.5%Pharmaceuticals6.1%Distributors1.6%Diversified Consumer Services1.1%Health Care Equipment & Supplies1.0%Health Care Providers & Services0.4%Renewable Energy0.3%SubIndustry ExposureBiotechnology85.8%Pharmaceuticals10.4%Life Sciences Tools & Services0.8%Health Care Services0.4%Renewable Energy Equipment0.3%Health Care Equipment0.2% Related Companies and Tools Related Companies PTH Portfolio XHS Portfolio KURE Portfolio RXL Portfolio SURI Portfolio LFSC Portfolio LABD Portfolio BIB Portfolio HEAL Portfolio XHE Portfolio This page (NYSEARCA:SBIO) was last updated on 10/6/2025 by MarketBeat.com Staff From Our PartnersGold surges past $3,600 … but this has beat gold by 1,000xGold has surged past $3,600 an ounce — up 45% in the past year — but one veteran metals analyst says the real ...Weiss Ratings | SponsoredGenerate up to $5,000/month with 10X less money?The secret to retiring without a million-dollar nest egg. 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