NYSEARCA:SBIO ALPS Medical Breakthroughs ETF (SBIO) Price, Holdings, & News $70.33 +1.69 (+2.46%) As of 08/25/2026 04:10 PM Eastern Add Compare Share Share Stock Analysis Stock AnalysisChartHoldingsNews and TrendsOwnershipRatingsShort Interest About ALPS Medical Breakthroughs ETF (NYSEARCA:SBIO) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get SBIO alerts:Sign Up Key Stats Today's Range$69.39▼$70.5950-Day Range$54.25▼$70.7952-Week Range$34.50▼$70.85Volume86,746 shsAverage Volume38,114 shsMarket Capitalization$222.95 millionAssets Under ManagementN/ADividend YieldN/ANet Expense Ratio0.50%Aggregate RatingModerate Buy ETF Overview The ALPS Medical Breakthroughs ETF (SBIO) is an exchange-traded fund that is based on the S-Network Medical Breakthroughs index. The fund tracks, a market-cap weighted index comprising US-listed biotech companies with one or more drugs currently in either Phase II or Phase III FDA clinical trials. SBIO was launched on Dec 31, 2014 and is managed by ALPS. Read More ALPS Medical Breakthroughs ETF ExpensesTypeSBIOHealth Care ETFsEquity ETFsNYSEARCA ETFsAll ETFsManagement Fee0.50%0.55%0.57%0.51%0.53%Other Expenses0.00%0.52%0.53%0.60%0.54%Total Expense0.50%0.76%0.75%0.75%0.73%Fee Waiver0.00%-0.85%-0.67%-0.77%-0.68%Net Expense0.50%0.58%0.63%0.57%0.60% Receive SBIO Stock News and Ratings via Email Sign-up to receive the latest news and ratings for ALPS Medical Breakthroughs ETF and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsSMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. 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Behind the scenes, Executive Order 14241 is orchestrating what analyst Porter Stansberry calls a total U.S. money reset, bypassing conventional legal channels under the guise of national security. The last time America reset its currency - under Nixon in the 1970s - it created an average of 1,300 new millionaires a day for over 50 years. Stansberry has identified three asset categories connected to Trump's initiative that could surge, plus his single top investment move. | Porter & Company (Ad)CREATOR TV SPORTS™ UNVEILS CREATOR LINEUP FOR INAUGURAL "CREATOR PICKLEBALL TOUR" AT VIDCON ANAHEIMJune 15, 2026 | prnewswire.comSBIO: Leaning Into Drug Discovery And Medical BreakthroughsApril 28, 2026 | seekingalpha.comCreator TV® Announces 2026 Sports Programming under Studio Label, Creator TV SportsApril 2, 2026 | prnewswire.comSee More Headlines SBIO ETF - Frequently Asked Questions How have SBIO shares performed this year? ALPS Medical Breakthroughs ETF's stock was trading at $51.22 at the beginning of 2026. Since then, SBIO shares have increased by 37.3% and is now trading at $70.33. Who are ALPS Medical Breakthroughs ETF's major shareholders? ALPS Medical Breakthroughs ETF's top institutional shareholders include Fulcrum Equity Management (0.14%) and Harbor Investment Advisory LLC (0.02%). How do I buy shares of ALPS Medical Breakthroughs ETF? Shares of SBIO stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of ALPS Medical Breakthroughs ETF own? Based on aggregate information from My MarketBeat watchlists, some other companies that ALPS Medical Breakthroughs ETF investors own include Waste Connections (WCN), American Water Works (AWK), iShares Micro-Cap ETF (IWC), The RMR Group (RMR), AUO (AUOTY), DiamondRock Hospitality (DRH) and Triple Flag Precious Metals (TFPM). Fund Details IssuerALPS Fund NameALPS Medical Breakthroughs ETF Tax ClassificationRegulated Investment Company Stock ExchangeNYSEARCACurrent SymbolNYSEARCA:SBIO Inception Date12/30/2014 Fund ManagerRyan Mischker, Andrew Hicks WebN/A PhoneN/AFund Focus Asset ClassEquity BenchmarkS-Network Medical Breakthroughs Index CategorySector FocusHealth Care Development LevelDeveloped Markets RegionNorth America Number of Holdings109 Fund Statistics Assets Under Management$0.00 Average Daily Volume$39.53 thousand Discount/Premium0.00% Administrator, Advisor and Custodian AdministratorALPS Fund Services, Inc. AdvisorALPS Advisors, Inc. CustodianState Street Bank and Trust Company DistributorALPS Distributors, Inc. Transfer AgentState Street Bank and Trust Company TrusteeN/A Lead Market MakerGTS Options OptionableOptionable Options Volume25 Put Options4 Call Options21 Short Interest78,401 shs Miscellaneous Outstanding Shares3,170,000Beta0.74 Creation Unit50,000 Creation Fee$500.00 10 Stocks Powering The Next AI Boom The AI boom is creating opportunities across semiconductors, cloud computing, enterprise software, infrastructure, cybersecurity, and automation. Inside this report, you’ll find 10 companies positioned to benefit as artificial intelligence moves from hype to real-world deployment and becomes a core growth driver for corporate America.Get This Free Report Top 10 SBIO HoldingsCrinetics Pharmaceuticals (NASDAQ:CRNX)Holding Weight: 4.55%Apogee Therapeutics (NASDAQ:APGE)Holding Weight: 4.24%Oruka Therapeutics (NASDAQ:ORKA)Holding Weight: 3.41%CG Oncology (NASDAQ:CGON)Holding Weight: 3.37%Dianthus Therapeutics (NASDAQ:DNTH)Holding Weight: 3.23%Xenon Pharmaceuticals (NASDAQ:XENE)Holding Weight: 3.07%Travere Therapeutics (NASDAQ:TVTX)Holding Weight: 2.94%ACADIA Pharmaceuticals (NASDAQ:ACAD)Holding Weight: 2.46%Edgewise Therapeutics (NASDAQ:EWTX)Holding Weight: 2.42%Veradermics (NYSE:MANE)Holding Weight: 2.39%Full Holdings DetailsSBIO Sector ExposureSBIO Industry Exposure This page (NYSEARCA:SBIO) was last updated on 8/26/2026 by MarketBeat.com Staff. 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