NYSEARCA:XBI SPDR S&P Biotech ETF (XBI) Price, Holdings, & News $164.38 -0.99 (-0.60%) As of 09/3/2026 04:10 PM Eastern Add Compare Share Share Stock Analysis Stock AnalysisChartDividendHoldingsNews and TrendsOwnershipRatingsShort Interest About SPDR S&P Biotech ETF (NYSEARCA:XBI) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get SPDR S&P Biotech ETF alerts:Sign Up Key Stats Today's Range$162.85▼$165.9650-Day Range$147.01▼$169.5552-Week Range$92.49▼$169.89Volume5.40 million shsAverage Volume9.14 million shsMarket Capitalization$10.73 billionAssets Under Management$11.55 billionDividend Yield0.35%Net Expense Ratio0.35%Aggregate RatingModerate Buy ETF Overview SPDR S&P Biotech ETF (the Fund) seeks to closely match the returns and characteristics of the S&P Biotechnology Select Industry Index. The S&P Biotechnology Select Industry Index represents the biotechnology sub-industry portion of the S&P Total Markets Index. The S&P TMI tracks all the United States common stocks listed on the New York Stock Exchange, American Stock Exchange, National Association of Securities Dealers Automated Quotation (NASDAQ) National Market and NASDAQ Small Cap exchanges. The Biotech Index is a modified equal weight index. SSgA Funds Management, Inc. is the Fund's investment advisor. Read More SPDR S&P Biotech ETF ExpensesTypeXBIHealth Care ETFsEquity ETFsNYSEARCA ETFsAll ETFsManagement Fee0.35%0.55%0.57%0.50%0.53%Other Expenses0.00%0.52%0.53%0.60%0.54%Total Expense0.35%0.76%0.75%0.75%0.73%Fee Waiver0.00%-0.85%-0.67%-0.78%-0.68%Net Expense0.35%0.58%0.63%0.57%0.60% Receive XBI Stock News and Ratings via Email Sign-up to receive the latest news and ratings for SPDR S&P Biotech ETF and its competitors with MarketBeat's FREE daily newsletter. 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XBI ETF News HeadlinesAfter-hours Gainers: HOWL Jumps 90%, MODD To Begin Pivot Pump Rollout, BIVI Awaits Long COVID Data August 20, 2026 | rttnews.comXBI: Biotech's Breakthrough Moment Happend This Week (Upgrade)August 20, 2026 | seekingalpha.comBezos… DOOMEDA single FCC filing hints Elon Musk is planning his biggest project yet - bigger than Tesla, SpaceX, and X combined - aimed at the $25 trillion AI industry. James Altucher says the plan could cut Amazon out of the AI race and disrupt Blue Origin, with a key deadline landing September 25. | Paradigm Press (Ad)XBI vs. FBT: Broad Biotech Exposure or Concentrated Bets?August 19, 2026 | finance.yahoo.comWhich Healthcare ETF Is the Better Buy: VanEck's Pharma PPH or State Street's Biotech XBI?August 18, 2026 | finance.yahoo.comiShares Global Healthcare ETF vs State Street SPDR Biotech ETF. Which Healthcare-Focused Fund Will Bring You Profits in 2026 and Beyond?August 8, 2026 | fool.comSee More Headlines XBI ETF - Frequently Asked Questions How have XBI shares performed this year? SPDR S&P Biotech ETF's stock was trading at $121.93 at the start of the year. Since then, XBI shares have increased by 34.8% and is now trading at $164.38. Who are SPDR S&P Biotech ETF's major shareholders? SPDR S&P Biotech ETF's top institutional investors include Northwestern Mutual Wealth Management Co. (0.48%), Annex Advisory Services LLC (0.37%), Wellington Management Group LLP (0.19%) and Polymer Capital Management HK LTD (0.16%). How do I buy shares of SPDR S&P Biotech ETF? Shares of XBI stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of SPDR S&P Biotech ETF own? Based on aggregate information from My MarketBeat watchlists, some other companies that SPDR S&P Biotech ETF investors own include American Water Works (AWK), Waste Connections (WCN), The RMR Group (RMR), iShares Micro-Cap ETF (IWC), Voyager Therapeutics (VYGR), DiamondRock Hospitality (DRH) and Humana (HUM). Fund Details IssuerSSgA Fund NameSPDR S&P Biotech ETF Tax ClassificationRegulated Investment Company Stock ExchangeNYSEARCACurrent SymbolNYSEARCA:XBI Inception Date1/31/2006 Fund ManagerMichael Feehily, Karl Schneider, Raymond Donofrio Webwww.spdrs.com Phone+1-866-7872257Fund Focus Asset ClassEquity BenchmarkS&P Biotechnology Select Industry Index CategorySector FocusHealth Care Development LevelDeveloped Markets RegionNorth America Number of Holdings163 Fund Statistics Assets Under Management$11.55 billion Average Daily Volume$8.37 million Discount/Premium0.04% Administrator, Advisor and Custodian AdministratorState Street Global Advisors Funds Management, Inc. AdvisorSSgA Funds Management, Inc. CustodianState Street Bank and Trust Company DistributorState Street Global Advisors Funds Distributors, LLC Transfer AgentState Street Bank and Trust Company TrusteeN/A Lead Market MakerVirtu Financial Options OptionableOptionable Options Volume53,778 Put Options40,245 Call Options13,533 Short Interest77,134,345 shs Miscellaneous Outstanding Shares65,300,000Beta0.84 Creation Unit50,000 Creation Fee$250.00 The 10 Best High-Yield Dividend Stocks for 2026Discover the 10 Best High-Yield Dividend Stocks for 2026 and secure reliable income in uncertain markets. Download the report now to identify top dividend payers and avoid common yield traps.Get This Free Report Top 10 XBI HoldingsTwist Bioscience (NASDAQ:TWST)Holding Weight: 1.76%Oruka Therapeutics (NASDAQ:ORKA)Holding Weight: 1.61%Apogee Therapeutics (NASDAQ:APGE)Holding Weight: 1.55%Praxis Precision Medicines (NASDAQ:PRAX)Holding Weight: 1.46%Kymera Therapeutics (NASDAQ:KYMR)Holding Weight: 1.39%Dianthus Therapeutics (NASDAQ:DNTH)Holding Weight: 1.37%Natera (NASDAQ:NTRA)Holding Weight: 1.37%Halozyme Therapeutics (NASDAQ:HALO)Holding Weight: 1.36%Protagonist Therapeutics (NASDAQ:PTGX)Holding Weight: 1.36%Revolution Medicines (NASDAQ:RVMD)Holding Weight: 1.33%Full Holdings DetailsXBI Sector ExposureXBI Industry Exposure This page (NYSEARCA:XBI) was last updated on 9/4/2026 by MarketBeat.com Staff. From Our PartnersThe 2026 beginners Guide to Gold IRAsGold trades near record highs while silver just topped $81 an ounce for the first time ever. 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