NYSEARCA:XBI SPDR S&P Biotech ETF (XBI) Price, Holdings, & News $129.48 +0.81 (+0.63%) As of 11:24 AM Eastern Add Compare Share Share Stock Analysis Stock AnalysisChartDividendHeadlinesHoldingsOwnershipRatingsShort InterestBuy This Stock About SPDR S&P Biotech ETF (NYSEARCA:XBI) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get SPDR S&P Biotech ETF alerts:Sign Up Key Stats Today's Range$128.50▼$131.0650-Day Range$118.78▼$138.6752-Week Range$80.90▼$139.19Volume2.64 million shsAverage Volume9.17 million shsMarket Capitalization$8.26 billionAssets Under Management$7.86 billionDividend Yield0.34%Net Expense Ratio0.35%Aggregate RatingModerate Buy ETF Overview SPDR S&P Biotech ETF (the Fund) seeks to closely match the returns and characteristics of the S&P Biotechnology Select Industry Index. The S&P Biotechnology Select Industry Index represents the biotechnology sub-industry portion of the S&P Total Markets Index. The S&P TMI tracks all the United States common stocks listed on the New York Stock Exchange, American Stock Exchange, National Association of Securities Dealers Automated Quotation (NASDAQ) National Market and NASDAQ Small Cap exchanges. The Biotech Index is a modified equal weight index. SSgA Funds Management, Inc. is the Fund's investment advisor. Read More SPDR S&P Biotech ETF ExpensesTypeXBIHealth Care ETFsEquity ETFsNYSEARCA ETFsAll ETFsManagement Fee0.35%0.56%0.57%0.51%0.53%Other Expenses0.00%0.47%0.55%0.58%0.55%Total Expense0.35%0.74%0.76%0.74%0.73%Fee Waiver0.00%-0.71%-0.64%-0.70%-0.61%Net Expense0.35%0.59%0.63%0.58%0.60% Receive XBI Stock News and Ratings via Email Sign-up to receive the latest news and ratings for SPDR S&P Biotech ETF and its competitors with MarketBeat's FREE daily newsletter. 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XBI ETF News Headlines3 Longevity ETFs to Buy and Hold (and Hold)The size of the longevity industry could roughly triple in the next decade, and these ETFs may help to provide access to a fast-growing space.4 hours ago | marketbeat.com‘Buying stuff like it's going out of fashion': Biotech M&A on track for best year since pre-CovidJune 4, 2026 | cnbc.comThis is the worst news for stocks in 50 yearsGoldman Sachs and Morgan Stanley are issuing a rare warning: what's ahead for U.S. stocks could be the worst environment in 50 years - with portfolios potentially staying in the red for 10 years or longer. From rate spikes in 2022 to $12 trillion wiped out in 30 days during the Iran War, Wall Street suggests the volatility isn't slowing down. TradeSmith CEO Keith Kaplan is showing investors what steps to take now to prepare their wealth before this worsens.June 8 at 1:00 AM | TradeSmith (Ad)VHT vs. XBI: Vanguard Health Care ETF Tops SPDR Biotech in Yield and CostMay 28, 2026 | finance.yahoo.comBiotech Investors Are Tuning Out the MAHA ChaosMay 20, 2026 | wsj.com2 Ways to Play the Big Pharma Patent CliffWith hundreds of billions in sales on the line for drugs that will lose their patent exclusivity in the coming years, two biotech ETFs can help capitalize.May 14, 2026 | marketbeat.comSee More Headlines XBI ETF - Frequently Asked Questions How have XBI shares performed this year? SPDR S&P Biotech ETF's stock was trading at $121.93 at the beginning of the year. Since then, XBI shares have increased by 5.9% and is now trading at $129.18. Who are SPDR S&P Biotech ETF's major shareholders? SPDR S&P Biotech ETF's top institutional shareholders include Bank of America Corp DE (22.76%), Healthcare of Ontario Pension Plan Trust Fund (15.28%), Bessemer Group Inc. (2.83%) and Meitav Investment House Ltd. (1.27%). How do I buy shares of SPDR S&P Biotech ETF? Shares of XBI stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of SPDR S&P Biotech ETF own? Based on aggregate information from My MarketBeat watchlists, some other companies that SPDR S&P Biotech ETF investors own include American Water Works (AWK), Waste Connections (WCN), The RMR Group (RMR), iShares Micro-Cap ETF (IWC), Voyager Therapeutics (VYGR), DiamondRock Hospitality (DRH) and Humana (HUM). Fund Details IssuerSSgA Fund NameSPDR S&P Biotech ETF Tax ClassificationRegulated Investment Company Stock ExchangeNYSEARCACurrent SymbolNYSEARCA:XBI Inception Date1/31/2006 Fund ManagerMichael Feehily, Karl Schneider, Raymond Donofrio Webwww.spdrs.com Phone+1-866-7872257Fund Focus Asset ClassEquity BenchmarkS&P Biotechnology Select Industry Index CategorySector FocusHealth Care Development LevelDeveloped Markets RegionNorth America Number of Holdings162 Fund Statistics Assets Under Management$7.86 billion Average Daily Volume$8.45 million Discount/Premium-0.08% Administrator, Advisor and Custodian AdministratorState Street Global Advisors Funds Management, Inc. AdvisorSSgA Funds Management, Inc. CustodianState Street Bank and Trust Company DistributorState Street Global Advisors Funds Distributors, LLC Transfer AgentState Street Bank and Trust Company TrusteeN/A Lead Market MakerVirtu Financial Options OptionableOptionable Options Volume32,804 Put Options10,253 Call Options22,551 Short Interest74,340,000 shs Miscellaneous Outstanding Shares63,800,000Beta0.85 Creation Unit50,000 Creation Fee$250.00 Ten Starter Stocks For Beginners to Buy NowJust getting into the stock market? These 10 simple stocks can help beginning investors build long-term wealth without knowing options, technicals, or other advanced strategies.Get This Free Report Top 10 XBI HoldingsRevolution Medicines (NASDAQ:RVMD)Holding Weight: 1.78%Travere Therapeutics (NASDAQ:TVTX)Holding Weight: 1.75%TG Therapeutics (NASDAQ:TGTX)Holding Weight: 1.62%Alkermes (NASDAQ:ALKS)Holding Weight: 1.55%Arrowhead Pharmaceuticals (NASDAQ:ARWR)Holding Weight: 1.51%Twist Bioscience (NASDAQ:TWST)Holding Weight: 1.51%Cytokinetics (NASDAQ:CYTK)Holding Weight: 1.41%Neurocrine Biosciences (NASDAQ:NBIX)Holding Weight: 1.41%Exelixis (NASDAQ:EXEL)Holding Weight: 1.40%Madrigal Pharmaceuticals (NASDAQ:MDGL)Holding Weight: 1.40%Full Holdings DetailsXBI Sector ExposureXBI Industry Exposure This page (NYSEARCA:XBI) was last updated on 6/8/2026 by MarketBeat.com Staff. 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