NYSEARCA:XBI SPDR S&P Biotech ETF (XBI) Price, Holdings, & News $107.80 -0.11 (-0.10%) Closing price 10/17/2025 04:10 PM EasternExtended Trading$107.90 +0.10 (+0.09%) As of 10/17/2025 07:59 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisChartDividendHeadlinesHoldingsOwnershipRatingsShort InterestBuy This Stock About SPDR S&P Biotech ETF (NYSEARCA:XBI) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get SPDR S&P Biotech ETF alerts:Sign Up Key Stats Today's Range$106.50▼$108.8450-Day Range$85.16▼$108.3752-Week Range$66.66▼$110.96Volume9.97 million shsAverage Volume10.43 million shsMarket Capitalization$6.70 billionAssets Under Management$6.73 billionDividend Yield0.04%Net Expense Ratio0.35%Aggregate RatingModerate Buy ETF Overview SPDR S&P Biotech ETF (the Fund) seeks to closely match the returns and characteristics of the S&P Biotechnology Select Industry Index. The S&P Biotechnology Select Industry Index represents the biotechnology sub-industry portion of the S&P Total Markets Index. The S&P TMI tracks all the United States common stocks listed on the New York Stock Exchange, American Stock Exchange, National Association of Securities Dealers Automated Quotation (NASDAQ) National Market and NASDAQ Small Cap exchanges. The Biotech Index is a modified equal weight index. SSgA Funds Management, Inc. is the Fund's investment advisor. Read More SPDR S&P Biotech ETF ExpensesTypeXBIHealth Care ETFsEquity ETFsNYSEARCA ETFsAll ETFsManagement Fee0.35%0.56%0.56%0.51%0.53%Other Expenses0.00%0.47%0.56%0.59%0.56%Total Expense0.35%0.75%0.76%0.74%0.73%Fee Waiver0.00%-0.67%-0.66%-0.71%-0.63%Net Expense0.35%0.60%0.63%0.58%0.60% Receive XBI Stock News and Ratings via Email Sign-up to receive the latest news and ratings for SPDR S&P Biotech ETF and its competitors with MarketBeat's FREE daily newsletter. 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Why Mizuho’s Jared Holz Is Optimistic This Time.October 17 at 5:19 PM | msn.comWhy Biotech’s Rally Can Last This TimeOctober 13, 2025 | msn.comBuy alert: Move $1,000 before Tesla’s Optimus launchElon's $1,000,000,000,000 payday Elon Musk just made his biggest insider purchase of Tesla stock ever. He's preparing for a "mind blowing" new launch that could see Tesla move away from electric cars... and into a new market.October 18 at 2:00 AM | Altimetry (Ad)Biotech Stocks Have Struggled Since 2021. Why They're Coming Back.October 10, 2025 | barrons.com4 Biotech Stocks Seeing Explosive Momentum GainsOctober 7, 2025 | benzinga.comBiotech Stocks Are Up. The Sector Is Looking Better Than It Has in Years.October 6, 2025 | msn.comSee More Headlines XBI ETF - Frequently Asked Questions How have XBI shares performed this year? SPDR S&P Biotech ETF's stock was trading at $90.06 at the beginning of the year. Since then, XBI stock has increased by 19.7% and is now trading at $107.80. Who are SPDR S&P Biotech ETF's major shareholders? SPDR S&P Biotech ETF's top institutional investors include Weatherly Asset Management L. P. (0.26%), L. Roy Papp & Associates LLP (0.23%), Edge Wealth Management LLC (0.19%) and Marotta Asset Management (0.12%). How do I buy shares of SPDR S&P Biotech ETF? Shares of XBI stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of SPDR S&P Biotech ETF own? Based on aggregate information from My MarketBeat watchlists, some other companies that SPDR S&P Biotech ETF investors own include American Water Works (AWK), Waste Connections (WCN), The RMR Group (RMR), iShares Micro-Cap ETF (IWC), Voyager Therapeutics (VYGR), DiamondRock Hospitality (DRH) and Humana (HUM). Fund Details IssuerSSgA Fund NameSPDR S&P Biotech ETF Tax ClassificationRegulated Investment Company Stock ExchangeNYSEARCACurrent SymbolNYSEARCA:XBI Inception Date1/31/2006 Fund ManagerMichael Feehily, Karl Schneider, Raymond Donofrio Webwww.spdrs.com Phone+1-866-7872257Fund Focus Asset ClassEquity BenchmarkS&P Biotechnology Select Industry Index CategorySector FocusHealth Care Development LevelDeveloped Markets RegionNorth America Number of Holdings145 Fund Statistics Assets Under Management$6.76 billion Average Daily Volume$10.63 million Discount/Premium0.03% Administrator, Advisor and Custodian AdministratorSSgA Funds Management, Inc. AdvisorSSgA Funds Management, Inc. CustodianState Street Bank and Trust Company DistributorState Street Global Advisors Funds Distributors, LLC Transfer AgentState Street Bank and Trust Company TrusteeN/A Lead Market MakerVirtu Financial Options OptionableOptionable Options Volume76,370 Put Options26,311 Call Options50,059 Short Interest77,520,000 shs Miscellaneous Outstanding Shares59,530,000Beta0.97 Creation Unit50,000 Creation Fee$250.00 7 Energy Stocks to Buy and Hold ForeverWith the proliferation of data centers and electric vehicles, the electric grid will only get more strained. Download this report to learn how energy stocks can play a role in your portfolio as the global demand for energy continues to grow.Get This Free Report Top 10 XBI HoldingsCRISPR Therapeutics (NASDAQ:CRSP)Holding Weight: 2.48%Moderna (NASDAQ:MRNA)Holding Weight: 2.07%AbbVie (NYSE:ABBV)Holding Weight: 1.99%United Therapeutics (NASDAQ:UTHR)Holding Weight: 1.99%Exelixis (NASDAQ:EXEL)Holding Weight: 1.95%Biogen (NASDAQ:BIIB)Holding Weight: 1.93%Regeneron Pharmaceuticals (NASDAQ:REGN)Holding Weight: 1.92%Amgen (NASDAQ:AMGN)Holding Weight: 1.90%Ionis Pharmaceuticals (NASDAQ:IONS)Holding Weight: 1.90%Vertex Pharmaceuticals (NASDAQ:VRTX)Holding Weight: 1.87%Full Holdings DetailsXBI Sector ExposureXBI Industry Exposure This page (NYSEARCA:XBI) was last updated on 10/18/2025 by MarketBeat.com Staff From Our PartnersHoly ****... 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