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Avidity Partners Management Lp Top Holdings and 13F Report (2025)

About Avidity Partners Management Lp

Investment Activity

  • Avidity Partners Management Lp has $524.68 million in total holdings as of March 31, 2025.
  • Avidity Partners Management Lp owns shares of 64 different stocks, but just 31 companies or ETFs make up 80% of its holdings.
  • Approximately 24.36% of the portfolio was purchased this quarter.
  • About 95.25% of the portfolio was sold this quarter.
  • This quarter, Avidity Partners Management Lp has purchased 62 new stocks and bought additional shares in 4 stocks.
  • Avidity Partners Management Lp sold shares of 35 stocks and completely divested from 19 stocks this quarter.

Largest Holdings

Humana
$42,600,600
Boston Scientific
$33,895,680
DIANTHUS THERAPEUTICS INC
$31,217,162
UnitedHealth Group
$26,449,375
CG ONCOLOGY INC
$24,023,270

Largest New Holdings this Quarter

07373V105 - Beam Therapeutics
$13,856,867 Holding
03073E105 - Cencora
$10,928,937 Holding
372303206 - Genmab A/S
$8,480,098 Holding
68622V106 - Organon & Co.
$7,966,150 Holding
78464A870 - SPDR S&P Biotech ETF
$7,623,400 Holding

Largest Purchases this Quarter

Humana
71,800 shares (about $19.00M)
Beam Therapeutics
709,517 shares (about $13.86M)
Cencora
39,300 shares (about $10.93M)
Regeneron Pharmaceuticals
17,000 shares (about $10.78M)
Genmab A/S
433,100 shares (about $8.48M)

Largest Sales this Quarter

Mirum Pharmaceuticals
626,200 shares (about $28.21M)
DIANTHUS THERAPEUTICS INC
1,152,098 shares (about $20.90M)
Jazz Pharmaceuticals
154,500 shares (about $19.18M)
Boston Scientific
179,000 shares (about $18.06M)
Neurocrine Biosciences
134,700 shares (about $14.90M)

Sector Allocation Over Time

Map of 500 Largest Holdings ofAvidity Partners Management Lp

 
 
Selling
 
 
Neutral
 
 
Buying
Issuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSector
Humana Inc. stock logo
HUM
Humana
$42,600,600$18,998,280 80.5%161,0008.1%Medical
Boston Scientific Co. stock logo
BSX
Boston Scientific
$33,895,680$18,057,520 -34.8%336,0006.5%Medical
DIANTHUS THERAPEUTICS INC
$31,217,162$20,899,058 -40.1%1,720,9025.9%COM
UnitedHealth Group Incorporated stock logo
UNH
UnitedHealth Group
$26,449,375$4,975,625 -15.8%50,5005.0%Medical
CG ONCOLOGY INC
$24,023,270$2,861,852 -10.6%980,9424.6%COM
Natera, Inc. stock logo
NTRA
Natera
$16,856,072$14,791,486 -46.7%119,2003.2%Medical
Syndax Pharmaceuticals, Inc. stock logo
SNDX
Syndax Pharmaceuticals
$16,275,625$2,149,611 -11.7%1,325,0003.1%Medical
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
$16,109,442$10,781,910 202.4%25,4003.1%Medical
Exact Sciences Co. stock logo
EXAS
Exact Sciences
$15,281,370$10,822,976 -41.5%353,0002.9%Medical
Beam Therapeutics Inc. stock logo
BEAM
Beam Therapeutics
$13,856,867$13,856,867 New Holding709,5172.6%Medical
Glaukos Co. stock logo
GKOS
Glaukos
$13,188,280$3,543,120 -21.2%134,0002.5%Medical
DexCom, Inc. stock logo
DXCM
DexCom
$12,292,200$9,424,020 -43.4%180,0002.3%Medical
Ultragenyx Pharmaceutical Inc. stock logo
RARE
Ultragenyx Pharmaceutical
$11,663,241$1,082,679 -8.5%322,1002.2%Medical
Cencora, Inc. stock logo
COR
Cencora
$10,928,937$10,928,937 New Holding39,3002.1%Medical
Jazz Pharmaceuticals plc stock logo
JAZZ
Jazz Pharmaceuticals
$9,932,000$19,181,175 -65.9%80,0001.9%Medical
Tenet Healthcare Co. stock logo
THC
Tenet Healthcare
$9,684,000$8,742,500 -47.4%72,0001.8%Medical
Neurocrine Biosciences, Inc. stock logo
NBIX
Neurocrine Biosciences
$9,478,420$14,897,820 -61.1%85,7001.8%Medical
Danaher Co. stock logo
DHR
Danaher
$9,122,500$4,612,500 -33.6%44,5001.7%Medical
Axsome Therapeutics, Inc. stock logo
AXSM
Axsome Therapeutics
$8,980,510$12,945,930 -59.0%77,0001.7%Medical
Genmab A/S stock logo
GMAB
Genmab A/S
$8,480,098$8,480,098 New Holding433,1001.6%Medical
Arvinas, Inc. stock logo
ARVN
Arvinas
$8,165,397$6,281,763 -43.5%1,163,1621.6%Medical
Insmed Incorporated stock logo
INSM
Insmed
$8,163,030$9,597,282 -54.0%107,0001.6%Medical
Organon & Co. stock logo
OGN
Organon & Co.
$7,966,150$7,966,150 New Holding535,0001.5%Medical
Thermo Fisher Scientific Inc. stock logo
TMO
Thermo Fisher Scientific
$7,712,800$14,480,160 -65.2%15,5001.5%Medical
Xenon Pharmaceuticals Inc. stock logo
XENE
Xenon Pharmaceuticals
$7,682,950$8,219,750 -51.7%229,0001.5%Medical
SPDR S&P Biotech ETF stock logo
XBI
SPDR S&P Biotech ETF
$7,623,400$7,623,400 New Holding94,0001.5%ETF
Centessa Pharmaceuticals plc stock logo
CNTA
Centessa Pharmaceuticals
$7,607,020$9,157,184 -54.6%529,0001.4%Medical
Revolution Medicines, Inc. stock logo
RVMD
Revolution Medicines
$7,531,680$8,245,952 -52.3%213,0001.4%Medical
Teva Pharmaceutical Industries Limited stock logo
TEVA
Teva Pharmaceutical Industries
$7,392,970$7,392,970 New Holding481,0001.4%Medical
Avantor, Inc. stock logo
AVTR
Avantor
$7,343,130$8,007,740 -52.2%453,0001.4%Medical
IDEAYA Biosciences, Inc. stock logo
IDYA
IDEAYA Biosciences
$7,289,100$11,166,246 -60.5%445,0001.4%Medical
Doximity, Inc. stock logo
DOCS
Doximity
$7,108,675$7,108,675 New Holding122,5001.4%Medical
Janux Therapeutics, Inc. stock logo
JANX
Janux Therapeutics
$6,966,000$13,065,300 -65.2%258,0001.3%Medical
HealthEquity, Inc. stock logo
HQY
HealthEquity
$6,892,860$6,892,860 New Holding78,0001.3%Medical
Blueprint Medicines Co. stock logo
BPMC
Blueprint Medicines
$6,062,935$9,567,931 -61.2%68,5001.2%Medical
United Therapeutics Co. stock logo
UTHR
United Therapeutics
$5,178,936$5,178,936 New Holding16,8001.0%Medical
Phathom Pharmaceuticals, Inc. stock logo
PHAT
Phathom Pharmaceuticals
$5,016,000$3,699,927 -42.5%800,0001.0%Medical
Immunic, Inc. stock logo
IMUX
Immunic
$4,855,305$3,828,072 -44.1%4,454,4080.9%Medical
Bruker Co. stock logo
BRKR
Bruker
$4,800,100$1,615,338 50.7%115,0000.9%Computer and Technology
PERSPECTIVE THERAPEUTICS INC
$4,680,185$1,059,313 -18.5%2,197,2700.9%COM NEW
Context Therapeutics Inc. stock logo
CNTX
Context Therapeutics
$4,576,0460.0%7,477,2000.9%Medical
ORUKA THERAPEUTICS INC
$3,612,7920.0%352,1240.7%COM
uniQure stock logo
QURE
uniQure
$3,563,720$1,210,520 51.4%336,2000.7%Medical
Biohaven Ltd. stock logo
BHVN
Biohaven
$3,485,800$1,872,716 -34.9%145,0000.7%Medical
ACADIA Pharmaceuticals Inc. stock logo
ACAD
ACADIA Pharmaceuticals
$2,807,090$2,807,090 New Holding169,0000.5%Medical
Royalty Pharma plc stock logo
RPRX
Royalty Pharma
$2,708,310$2,708,310 New Holding87,0000.5%Finance
BridgeBio Pharma, Inc. stock logo
BBIO
BridgeBio Pharma
$2,592,750$2,592,750 New Holding75,0000.5%Medical
KEZAR LIFE SCIENCES INC
$2,452,6880.0%502,6000.5%COM NEW
Akero Therapeutics, Inc. stock logo
AKRO
Akero Therapeutics
$2,307,360$1,012,000 -30.5%57,0000.4%Medical
Soleno Therapeutics, Inc. stock logo
SLNO
Soleno Therapeutics
$2,286,400$2,286,400 New Holding32,0000.4%Medical
Capricor Therapeutics Inc stock logo
CAPR
Capricor Therapeutics
$2,268,110$2,268,110 New Holding239,0000.4%Medical
LEXEO THERAPEUTICS INC
$2,238,150$2,238,150 New Holding645,0000.4%COM
Vera Therapeutics, Inc. stock logo
VERA
Vera Therapeutics
$2,185,820$216,180 -9.0%91,0000.4%Medical
REGENXBIO Inc. stock logo
RGNX
REGENXBIO
$1,859,000$1,944,800 -51.1%260,0000.4%Medical
Ionis Pharmaceuticals, Inc. stock logo
IONS
Ionis Pharmaceuticals
$1,810,200$1,810,200 New Holding60,0000.3%Medical
Mirum Pharmaceuticals, Inc. stock logo
MIRM
Mirum Pharmaceuticals
$1,802,000$28,210,310 -94.0%40,0000.3%Medical
NewAmsterdam Pharma stock logo
NAMS
NewAmsterdam Pharma
$1,391,960$5,854,420 -80.8%68,0000.3%Medical
agilon health, inc. stock logo
AGL
agilon health
$1,321,083$1,321,083 New Holding305,1000.3%Medical
SCYNEXIS, Inc. stock logo
SCYX
SCYNEXIS
$1,170,0450.0%1,228,9100.2%Medical
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
$868,480$868,480 New Holding23,0000.2%Medical
KARYOPHARM THERAPEUTICS INC
$503,277$503,277 New Holding134,5660.1%COM NEW
Enliven Therapeutics, Inc. stock logo
ELVN
Enliven Therapeutics
$222,384$222,384 New Holding11,3000.0%Medical
Hyperfine, Inc. stock logo
HYPR
Hyperfine
$159,143$691,948 -81.3%222,1740.0%Medical
Reviva Pharmaceuticals Holdings, Inc. stock logo
RVPH
Reviva Pharmaceuticals
$131,624$131,624 New Holding138,0000.0%Medical
Intuitive Surgical, Inc. stock logo
ISRG
Intuitive Surgical
$0$33,823,008 -100.0%00.0%Medical
Acadia Healthcare Company, Inc. stock logo
ACHC
Acadia Healthcare
$0$26,089,700 -100.0%00.0%Medical
Kymera Therapeutics, Inc. stock logo
KYMR
Kymera Therapeutics
$0$20,115,000 -100.0%00.0%Medical
Illumina, Inc. stock logo
ILMN
Illumina
$0$14,659,211 -100.0%00.0%Medical
AbbVie Inc. stock logo
ABBV
AbbVie
$0$14,340,390 -100.0%00.0%Medical
Rocket Pharmaceuticals, Inc. stock logo
RCKT
Rocket Pharmaceuticals
$0$13,239,981 -100.0%00.0%Medical
Bristol-Myers Squibb stock logo
BMY
Bristol-Myers Squibb
$0$12,160,400 -100.0%00.0%Medical
TransMedics Group, Inc. stock logo
TMDX
TransMedics Group
$0$11,996,140 -100.0%00.0%Medical
Surgery Partners, Inc. stock logo
SGRY
Surgery Partners
$0$10,885,614 -100.0%00.0%Medical
ORIC Pharmaceuticals, Inc. stock logo
ORIC
ORIC Pharmaceuticals
$0$10,210,164 -100.0%00.0%Medical
Incyte Co. stock logo
INCY
Incyte
$0$8,951,472 -100.0%00.0%Medical
Ascendis Pharma A/S stock logo
ASND
Ascendis Pharma A/S
$0$8,535,540 -100.0%00.0%Medical
Intra-Cellular Therapies, Inc. stock logo
ITCI
Intra-Cellular Therapies
$0$8,101,440 -100.0%00.0%Medical
Keros Therapeutics, Inc. stock logo
KROS
Keros Therapeutics
$0$3,324,300 -100.0%00.0%Medical
DYNE THERAPEUTICS INC
$0$2,261,760 -100.0%00.0%COM
Cogent Biosciences, Inc. stock logo
COGT
Cogent Biosciences
$0$2,239,411 -100.0%00.0%Medical
NEUMORA THERAPEUTICS INC.
$0$1,590,000 -100.0%00.0%COM
Karyopharm Therapeutics Inc. stock logo
KPTI
Karyopharm Therapeutics
$0$1,365,112 -100.0%00.0%Medical
BLUEBIRD BIO INC
$0$680,169 -100.0%00.0%COM NEW

Showing largest 100 holdings. View all holdings.
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