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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:APLS NASDAQ:MLTX NASDAQ:PGEN NASDAQ:PTGX On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeAPLSApellis Pharmaceuticals$27.61+3.9%$20.61$16.10▼$41.94$3.49B0.782.31 million shs1.03 million shsMLTXMoonLake Immunotherapeutics$54.11-0.1%$50.07$31.42▼$58.26$3.48B1.27475,300 shs384,559 shsPGENPrecigen$3.64+13.2%$1.78$0.65▼$3.90$1.08B1.873.48 million shs20.69 million shsPTGXProtagonist Therapeutics$56.00-0.4%$54.13$33.31▼$60.60$3.48B2.33929,056 shs351,825 shsBeginner's Guide To Retirement StocksEnter your email address and we'll send you MarketBeat's list of seven best retirement stocks and why they should be in your portfolio. Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceAPLSApellis Pharmaceuticals-0.37%0.00%+37.86%+49.49%-31.76%MLTXMoonLake Immunotherapeutics+2.81%-2.71%+1.06%+40.59%+9.40%PGENPrecigen-0.31%+68.06%+75.41%+130.94%+184.07%PTGXProtagonist Therapeutics-0.04%-0.86%+1.83%+22.48%+35.49%Compare MarketRank™CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & ValuationAPLSApellis Pharmaceuticals4.5202 of 5 stars4.31.00.04.43.32.50.6MLTXMoonLake Immunotherapeutics1.5903 of 5 stars3.41.00.00.01.02.50.0PGENPrecigen3.865 of 5 stars3.40.00.04.73.11.70.6PTGXProtagonist Therapeutics1.976 of 5 stars2.53.00.00.03.12.50.0Compare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceAPLSApellis Pharmaceuticals 2.58Moderate Buy$34.1225.09% UpsideMLTXMoonLake Immunotherapeutics 2.78Moderate Buy$74.4336.61% UpsidePGENPrecigen 2.80Moderate Buy$8.25126.52% UpsidePTGXProtagonist Therapeutics 3.00Buy$67.2020.06% UpsideCurrent Analyst Ratings BreakdownLatest PGEN, PTGX, APLS, and MLTX Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails8/19/2025PGENPrecigenCitigroupSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingOutperform ➝ Outperform8/19/2025PGENPrecigenJMP SecuritiesSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetMarket Outperform ➝ Market Outperform$6.00 ➝ $8.008/19/2025PGENPrecigenHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$8.508/15/2025PGENPrecigenJPMorgan Chase & Co.Subscribe to MarketBeat All Access for the recommendation accuracy ratingUpgradeUnderweight ➝ Neutral8/13/2025PGENPrecigenHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$6.008/7/2025PTGXProtagonist TherapeuticsCitigroupSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingOutperform ➝ Outperform8/7/2025PTGXProtagonist TherapeuticsJMP SecuritiesSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetMarket Outperform ➝ Market Outperform$67.00 ➝ $69.008/6/2025MLTXMoonLake ImmunotherapeuticsThe Goldman Sachs GroupSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetBuy ➝ Buy$74.00 ➝ $82.008/4/2025APLSApellis PharmaceuticalsJPMorgan Chase & Co.Subscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetOverweight ➝ Overweight$35.00 ➝ $37.008/1/2025APLSApellis PharmaceuticalsRoyal Bank Of CanadaSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetSector Perform ➝ Sector Perform$17.00 ➝ $19.008/1/2025APLSApellis PharmaceuticalsCantor FitzgeraldSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetOverweight ➝ Overweight$39.00 ➝ $40.00(Data available from 8/21/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookAPLSApellis Pharmaceuticals$781.37M4.41N/AN/A$1.24 per share22.00MLTXMoonLake ImmunotherapeuticsN/AN/AN/AN/A$5.57 per shareN/APGENPrecigen$4.34M250.05N/AN/A($0.12) per share-30.35PTGXProtagonist Therapeutics$434.43M8.01$4.50 per share12.45$10.74 per share5.21Compare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateAPLSApellis Pharmaceuticals-$197.88M-$1.82N/AN/AN/A-30.24%-116.09%-26.72%11/4/2025 (Estimated)MLTXMoonLake Immunotherapeutics-$118.94M-$2.78N/AN/AN/AN/A-40.98%-35.81%11/6/2025 (Estimated)PGENPrecigen-$126.24M-$0.42N/AN/AN/A-2,868.66%-842.83%-78.98%N/APTGXProtagonist Therapeutics$275.19M$0.7080.10N/AN/A24.88%8.12%7.41%11/6/2025 (Estimated)Latest PGEN, PTGX, APLS, and MLTX EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails8/12/2025Q2 2025PGENPrecigen-$0.14-$0.11+$0.03-$0.09$0.67 million$0.86 million8/6/2025Q2 2025PTGXProtagonist Therapeutics-$0.53-$0.55-$0.02-$0.55$8.32 million$5.55 million8/5/2025Q2 2025MLTXMoonLake Immunotherapeutics-$0.73-$0.87-$0.14-$0.87N/AN/A7/31/2025Q2 2025APLSApellis Pharmaceuticals-$0.44-$0.33+$0.11-$0.33$187.91 million$171.39 millionCompare DividendsCompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive GrowthAPLSApellis PharmaceuticalsN/AN/AN/AN/AN/AMLTXMoonLake ImmunotherapeuticsN/AN/AN/AN/AN/APGENPrecigenN/AN/AN/AN/AN/APTGXProtagonist TherapeuticsN/AN/AN/AN/AN/ACompare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioAPLSApellis Pharmaceuticals2.903.773.16MLTXMoonLake Immunotherapeutics0.2116.6516.65PGENPrecigenN/A2.712.71PTGXProtagonist TherapeuticsN/A16.9716.97Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipAPLSApellis Pharmaceuticals96.29%MLTXMoonLake Immunotherapeutics93.85%PGENPrecigen33.51%PTGXProtagonist Therapeutics98.63%Insider OwnershipCompanyInsider OwnershipAPLSApellis Pharmaceuticals6.50%MLTXMoonLake Immunotherapeutics12.02%PGENPrecigen47.10%PTGXProtagonist Therapeutics4.90%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableAPLSApellis Pharmaceuticals770126.29 million118.08 millionOptionableMLTXMoonLake Immunotherapeutics264.23 million56.51 millionOptionablePGENPrecigen190297.97 million157.63 millionOptionablePTGXProtagonist Therapeutics12062.21 million59.16 millionOptionablePGEN, PTGX, APLS, and MLTX HeadlinesRecent News About These CompaniesInvesco Ltd. Has $41.57 Million Position in Protagonist Therapeutics, Inc. $PTGXAugust 20 at 3:42 AM | marketbeat.comDeutsche Bank AG Has $3.18 Million Holdings in Protagonist Therapeutics, Inc. $PTGXAugust 20 at 3:24 AM | marketbeat.comE Fund Management Co. Ltd. Sells 71,950 Shares of Protagonist Therapeutics, Inc. (NASDAQ:PTGX)August 18 at 5:10 AM | marketbeat.comProtagonist Therapeutics, Inc. (NASDAQ:PTGX) Shares Bought by Public Sector Pension Investment BoardAugust 15, 2025 | marketbeat.comInformed Momentum Co LLC Takes Position in Protagonist Therapeutics, Inc. (NASDAQ:PTGX)August 13, 2025 | marketbeat.comKnott David M Jr Purchases 23,632 Shares of Protagonist Therapeutics, Inc. (NASDAQ:PTGX)August 12, 2025 | marketbeat.comDoes Protagonist Therapeutics’ (PTGX) Widening Loss and Shelf Registration Signal a Strategic Pivot?August 12, 2025 | finance.yahoo.comWedbush Issues Optimistic Estimate for PTGX EarningsAugust 12, 2025 | americanbankingnews.comWedbush Has Positive Estimate for PTGX Q3 EarningsAugust 11, 2025 | marketbeat.comWedbush Expects Higher Earnings for Protagonist TherapeuticsAugust 9, 2025 | marketbeat.com7PTGX : What 4 Analyst Ratings Have To Say About Protagonist...August 8, 2025 | benzinga.comJMP Securities Forecasts Strong Price Appreciation for Protagonist Therapeutics (NASDAQ:PTGX) StockAugust 8, 2025 | marketbeat.comProtagonist Therapeutics files automatic mixed securities shelfAugust 7, 2025 | msn.comProtagonist (PTGX) Q2 Revenue Falls 26%August 7, 2025 | fool.comProtagonist Therapeutics (PTGX) Reports Q2 Loss, Lags Revenue EstimatesAugust 6, 2025 | zacks.comProtagonist Reports Second Quarter 2025 Financial Results and Provides Corporate UpdateAugust 6, 2025 | accessnewswire.comAProtagonist Therapeutics, Inc. (NASDAQ:PTGX) Holdings Raised by XTX Topco LtdAugust 5, 2025 | marketbeat.comProtagonist Therapeutics, Inc. (NASDAQ:PTGX) Given Average Rating of "Buy" by AnalystsAugust 4, 2025 | marketbeat.comJupiter Asset Management Ltd. Makes New $8.13 Million Investment in Protagonist Therapeutics, Inc. (NASDAQ:PTGX)August 4, 2025 | marketbeat.comGSA Capital Partners LLP Acquires New Position in Protagonist Therapeutics, Inc. (NASDAQ:PTGX)August 4, 2025 | marketbeat.comProtagonist Therapeutics, Inc. (NASDAQ:PTGX) Stock Holdings Raised by Envestnet Asset Management Inc.August 4, 2025 | marketbeat.comNew MarketBeat Followers Over TimeMedia Sentiment Over TimePGEN, PTGX, APLS, and MLTX Company DescriptionsApellis Pharmaceuticals NASDAQ:APLS$27.61 +1.03 (+3.86%) Closing price 03:59 PM EasternExtended Trading$27.54 -0.07 (-0.25%) As of 04:10 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Apellis Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of therapeutic compounds through the inhibition of the complement system for autoimmune and inflammatory diseases. It offers EMPAVELI for the treatment of paroxysmal nocturnal hemoglobinuria, C3 glomerulopathy and immune complex membranoproliferative glomerulonephritis, and hematopoietic stem cell transplantation-associated thrombotic microangiopathy; and SYFOVRE for treating geographic atrophy secondary to age-related macular degeneration and geographic atrophy (GA). The company also develops APL-3007, a small interfering RNA, or siRNA, which is in a Phase 1 clinical trial, as well as an oral complement inhibitor that is in preclinical development. It has a collaboration and license agreement with Swedish Orphan Biovitrum AB (publ) for development and commercialization of pegcetacoplan; and a collaboration with Beam Therapeutics Inc. focused on the use of Beam's base editing technology to discover new treatments for complement-driven diseases. The company was incorporated in 2009 and is based in Waltham, Massachusetts.MoonLake Immunotherapeutics NASDAQ:MLTX$54.11 -0.03 (-0.06%) Closing price 03:59 PM EasternExtended Trading$54.14 +0.04 (+0.06%) As of 04:10 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.MoonLake Immunotherapeutics, a clinical-stage biopharmaceutical company, engages in developing therapies. It develops Sonelokimab, a novel investigational Nanobody for the treatment of inflammation diseases; and hidradenitis suppurativa, psoriatic arthritis, axial spondyloarthritis, and psoriasis. MoonLake Immunotherapeutics was incorporated in 2020 and is headquartered in Zug, Switzerland.Precigen NASDAQ:PGEN$3.64 +0.43 (+13.24%) Closing price 03:59 PM EasternExtended Trading$3.68 +0.05 (+1.24%) As of 04:17 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Precigen, Inc. operates as a discovery and clinical-stage biopharmaceutical company that develops gene and cell therapies using precision technology to target diseases in therapeutic areas of immuno-oncology, autoimmune disorders, and infectious diseases. It operates through two segments, Biopharmaceuticals and Exemplar. The company offers therapeutic platforms consisting of UltraCAR-T to provide chimeric antigen receptor T cell therapies for cancer patients; AdenoVerse immunotherapy, which utilizes a library of proprietary adenovectors for gene delivery of therapeutic effectors, immunomodulators, and vaccine antigen; and ActoBiotics for specific disease modification. It also develops programs based on the UltraCAR-T platform, including PRGN-3005 in Phase 1b clinical trial to treat advanced ovarian, fallopian tube, or primary peritoneal cancer; PRGN-3006 in Phase 1b trial for patients with relapsed or refractory acute myeloid leukemia and high-risk myelodysplastic syndromes; and PRGN-3007 in Phase 1/1b trial for the treatment of advanced receptor tyrosine kinase-like orphan receptor 1-positive, hematologic, and solid tumors. In addition, the company is developing programs based on the AdenoVerse immunotherapy platform comprising PRGN-2009 in Phase 2 trial for patients with HPV-associated cancer; and PRGN-2012 in Phase ½ trial to treat recurrent respiratory papillomatosis, as well as AG019, which is based on the ActoBiotics platform and in Phase 1b/2a trial, to treat type 1 diabetes mellitus. Further, it provides UltraPorator, a proprietary electroporation device; and develops research models and services for healthcare research applications. The company was formerly known as Intrexon Corporation and changed its name to Precigen, Inc. in February 2020. Precigen, Inc. was founded in 1998 and is headquartered in Germantown, Maryland.Protagonist Therapeutics NASDAQ:PTGX$56.00 -0.23 (-0.42%) Closing price 03:59 PM EasternExtended Trading$56.00 +0.00 (+0.01%) As of 04:10 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Protagonist Therapeutics, Inc., a biopharmaceutical company, develops peptide-based drugs for hematology and blood disorders, and inflammatory and immunomodulatory diseases. It is developing Rusfertide (PTG-300), an injectable hepcidin mimetic that completed phase 2 clinical trials for the treatment of polycythemia vera and other blood disorders; and JNJ-2113, an orally delivered investigational drug to block biological pathways that completed phase 2b clinical trials for the treatment of moderate-to-severe plaque psoriasis; and PN-943, an orally delivered, gut-restricted alpha 4 beta 7 specific integrin antagonist completed a phase 2 clinical trials in patients with moderate to severe ulcerative colitis. The company has a license and collaboration agreement with Takeda to commercialize rusfertide; and JNJ Innovative Medicines to co-develop Interleukin-23 receptor antagonist compound JNJ-2113. Protagonist Therapeutics, Inc. was incorporated in 2006 and is headquartered in Newark, California. 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