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CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Aurinia Pharmaceuticals Inc. stock logo
AUPH
Aurinia Pharmaceuticals
$8.18
-0.6%
$7.99
$5.20
$10.67
$1.11B1.151.33 million shs942,470 shs
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
$17.29
-2.4%
$14.68
$10.91
$40.26
$1.04B2.72616,250 shs325,351 shs
Wave Life Sciences Ltd. stock logo
WVE
Wave Life Sciences
$6.95
-3.5%
$6.52
$4.25
$16.74
$1.07B-1.041.32 million shs672,535 shs
Zhengye Biotechnology Holding Limited stock logo
ZYBT
Zhengye Biotechnology
$6.34
-13.0%
$8.35
$3.50
$14.30
$299.03MN/A383,680 shs638,578 shs
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Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Aurinia Pharmaceuticals Inc. stock logo
AUPH
Aurinia Pharmaceuticals
0.00%-0.12%+0.37%+0.25%+50.09%
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
0.00%+1.89%+18.91%-4.16%-53.27%
Wave Life Sciences Ltd. stock logo
WVE
Wave Life Sciences
0.00%-3.74%+10.32%-32.00%+8.76%
Zhengye Biotechnology Holding Limited stock logo
ZYBT
Zhengye Biotechnology
0.00%+7.28%-16.80%+40.89%+633,999,900.00%
CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & Valuation
Aurinia Pharmaceuticals Inc. stock logo
AUPH
Aurinia Pharmaceuticals
3.2745 of 5 stars
3.52.00.00.04.10.81.9
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
2.4045 of 5 stars
3.61.00.00.02.52.50.6
Wave Life Sciences Ltd. stock logo
WVE
Wave Life Sciences
4.2523 of 5 stars
3.51.00.04.82.14.20.6
Zhengye Biotechnology Holding Limited stock logo
ZYBT
Zhengye Biotechnology
N/AN/AN/AN/AN/AN/AN/AN/A
CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
Aurinia Pharmaceuticals Inc. stock logo
AUPH
Aurinia Pharmaceuticals
3.00
Buy$11.5040.59% Upside
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
3.25
Buy$53.40208.85% Upside
Wave Life Sciences Ltd. stock logo
WVE
Wave Life Sciences
2.92
Moderate Buy$20.50194.96% Upside
Zhengye Biotechnology Holding Limited stock logo
ZYBT
Zhengye Biotechnology
0.00
N/AN/AN/A

Current Analyst Ratings Breakdown

Latest ZYBT, SYRE, WVE, and AUPH Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
6/11/2025
Wave Life Sciences Ltd. stock logo
WVE
Wave Life Sciences
Raymond James
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Initiated CoverageOutperform$14.00
5/5/2025
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
Wedbush
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingOutperform$65.00
4/29/2025
Wave Life Sciences Ltd. stock logo
WVE
Wave Life Sciences
Cantor Fitzgerald
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Initiated CoverageOverweight$10.00
4/8/2025
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
Leerink Partnrs
Subscribe to MarketBeat All Access for the recommendation accuracy rating
UpgradeStrong-Buy
4/8/2025
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
Leerink Partners
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Initiated CoverageOutperform$45.00
4/8/2025
Wave Life Sciences Ltd. stock logo
WVE
Wave Life Sciences
Wedbush
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Initiated CoverageOutperform$18.00
3/26/2025
Wave Life Sciences Ltd. stock logo
WVE
Wave Life Sciences
HC Wainwright
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Reiterated RatingBuy ➝ Buy$22.00 ➝ $22.00
3/18/2025
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
Wolfe Research
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Initiated CoverageOutperform$27.00
(Data available from 6/15/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)
CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
Aurinia Pharmaceuticals Inc. stock logo
AUPH
Aurinia Pharmaceuticals
$247.30M4.47N/AN/A$2.63 per share3.11
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
$890K1,170.98N/AN/A($0.22) per share-78.59
Wave Life Sciences Ltd. stock logo
WVE
Wave Life Sciences
$104.94M10.21N/AN/A$0.40 per share17.38
Zhengye Biotechnology Holding Limited stock logo
ZYBT
Zhengye Biotechnology
$189.75M1.58N/AN/AN/A
CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
Aurinia Pharmaceuticals Inc. stock logo
AUPH
Aurinia Pharmaceuticals
-$78.02M$0.28N/A14.61N/A-10.23%-4.41%-3.07%7/30/2025 (Estimated)
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
-$338.79M-$3.77N/AN/AN/AN/A-210.01%-44.40%8/6/2025 (Estimated)
Wave Life Sciences Ltd. stock logo
WVE
Wave Life Sciences
-$57.51M-$0.84N/AN/AN/A-66.50%-280.57%-52.90%8/6/2025 (Estimated)
Zhengye Biotechnology Holding Limited stock logo
ZYBT
Zhengye Biotechnology
N/AN/A0.00N/AN/AN/AN/AN/A

Latest ZYBT, SYRE, WVE, and AUPH Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
5/12/2025Q1 2025
Aurinia Pharmaceuticals Inc. stock logo
AUPH
Aurinia Pharmaceuticals
$0.08$0.16+$0.08$0.16$61.06 million$62.47 million
5/8/2025Q1 2025
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
-$0.76-$0.74+$0.02-$0.74N/AN/A
5/8/2025Q1 2025
Wave Life Sciences Ltd. stock logo
WVE
Wave Life Sciences
-$0.27-$0.29-$0.02-$0.29$11.65 million$9.18 million
CompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive Growth
Aurinia Pharmaceuticals Inc. stock logo
AUPH
Aurinia Pharmaceuticals
N/AN/AN/AN/AN/A
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
N/AN/AN/AN/AN/A
Wave Life Sciences Ltd. stock logo
WVE
Wave Life Sciences
N/AN/AN/AN/AN/A
Zhengye Biotechnology Holding Limited stock logo
ZYBT
Zhengye Biotechnology
N/AN/AN/AN/AN/A
CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
Aurinia Pharmaceuticals Inc. stock logo
AUPH
Aurinia Pharmaceuticals
0.17
5.60
5.11
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
N/A
7.32
7.32
Wave Life Sciences Ltd. stock logo
WVE
Wave Life Sciences
N/A
1.90
1.90
Zhengye Biotechnology Holding Limited stock logo
ZYBT
Zhengye Biotechnology
N/AN/AN/A

Institutional Ownership

CompanyInstitutional Ownership
Aurinia Pharmaceuticals Inc. stock logo
AUPH
Aurinia Pharmaceuticals
36.83%
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
80.39%
Wave Life Sciences Ltd. stock logo
WVE
Wave Life Sciences
89.73%
Zhengye Biotechnology Holding Limited stock logo
ZYBT
Zhengye Biotechnology
N/A
CompanyEmployeesShares OutstandingFree FloatOptionable
Aurinia Pharmaceuticals Inc. stock logo
AUPH
Aurinia Pharmaceuticals
300135.10 million137.02 millionOptionable
Spyre Therapeutics, Inc. stock logo
SYRE
Spyre Therapeutics
7360.28 million48.24 millionOptionable
Wave Life Sciences Ltd. stock logo
WVE
Wave Life Sciences
240154.13 million108.14 millionOptionable
Zhengye Biotechnology Holding Limited stock logo
ZYBT
Zhengye Biotechnology
27847.17 millionN/AN/A

New MarketBeat Followers Over Time

Media Sentiment Over Time

Aurinia Pharmaceuticals stock logo

Aurinia Pharmaceuticals NASDAQ:AUPH

$8.18 -0.05 (-0.61%)
Closing price 06/13/2025 04:00 PM Eastern
Extended Trading
$8.14 -0.04 (-0.55%)
As of 06/13/2025 04:23 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Aurinia Pharmaceuticals Inc., a commercial-stage biopharmaceutical company, focuses on developing and commercializing therapies to treat various diseases with unmet medical need in the United States. It offers LUPKYNIS for the treatment of adult patients with active lupus nephritis. It has a collaboration and license agreement with Otsuka Pharmaceutical Co., Ltd. The company was incorporated in 1993 and is headquartered in Edmonton, Canada.

Spyre Therapeutics stock logo

Spyre Therapeutics NASDAQ:SYRE

$17.29 -0.42 (-2.37%)
Closing price 06/13/2025 04:00 PM Eastern
Extended Trading
$17.28 0.00 (-0.03%)
As of 06/13/2025 05:50 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Spyre Therapeutics, Inc., a preclinical stage biotechnology company, focuses on developing therapeutics for patients living with inflammatory bowel disease (IBD). It develops SPY001, a human monoclonal immunoglobulin G1 antibody designed to bind selectively to the a4ß7 integrin being developed for the treatment of IBD (ulcerative colitis and Crohn's disease). The company is also developing SPY002, a human monoclonal antibody (mAb)candidates designed to bind to tumor necrosis factor-like ligand 1A; and SPY120, a combination of SPY001 (anti-a4ß7) and SPY002 (anti-TL1A) antibodies, which are in preclinical studies. In addition, its other early-stage programs include SPY003, an anti-IL-23 mAb; SPY004, a novel mechanism of action (MOA) mAb; SPY130, a combination of anti-a4ß7 and anti-IL-23 mAbs; and SPY230, a combination of anti-TL1A and anti-IL-23 mAbs. The company was formerly known as Aeglea BioTherapeutics, Inc. and changed its name to Spyre Therapeutics, Inc. in November 2023. Spyre Therapeutics, Inc. was incorporated in 2013 and is based in Waltham, Massachusetts.

Wave Life Sciences stock logo

Wave Life Sciences NASDAQ:WVE

$6.95 -0.25 (-3.47%)
Closing price 06/13/2025 04:00 PM Eastern
Extended Trading
$6.96 +0.00 (+0.07%)
As of 06/13/2025 04:29 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Wave Life Sciences Ltd., a clinical-stage biotechnology company, designs, develops, and commercializes ribonucleic acid (RNA) medicines through PRISM, a discovery and drug development platform. The company's RNA medicines platform, PRISM, combines multiple modalities, chemistry innovation, and deep insights into human genetics to deliver scientific breakthroughs that treat both rare and prevalent disorders. It is developing WVE-006, a RNA editing oligonucleotide for the treatment of alpha-1 antitrypsin deficiency; siRNA clinical candidate for the treatment of obesity and other metabolic disorders; WVE-N531, a exon skipping oligonucleotide for the treatment of duchenne muscular dystrophy; and WVE-003, an antisense silencing oligonucleotide for the treatment of Huntington's disease (HD). The company has collaboration agreements with GlaxoSmithKline for the research, development, and commercialization of oligonucleotide therapeutics; Takeda Pharmaceutical Company Limited for the research, development, and commercialization of oligonucleotide therapeutics for disorders of the Central Nervous System; and Asuragen, Inc. for the development and potential commercialization of companion diagnostics for investigational allele-selective therapeutic programs targeting HD. Wave Life Sciences Ltd. was incorporated in 2012 and is based in Singapore.

Zhengye Biotechnology stock logo

Zhengye Biotechnology NASDAQ:ZYBT

$6.34 -0.95 (-13.03%)
As of 06/13/2025 04:00 PM Eastern

Zhengye Biotechnology Holding Limited is a veterinary vaccine manufacturer which encompasses research, development, manufacturing and sales of veterinary vaccines, with a focus on livestock vaccine principally in China. Zhengye Biotechnology Holding Limited is based in Jilin, China.