NASDAQ:VRTX Vertex Pharmaceuticals (VRTX) Stock Price, News & Analysis $516.34 +3.08 (+0.60%) Closing price 09/17/2026 04:00 PM EasternExtended Trading$517.46 +1.12 (+0.22%) As of 06:27 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsInsider TradesNews and TrendsOptions ChainOwnershipSEC FilingsShort Interest About Vertex Pharmaceuticals Stock (NASDAQ:VRTX) View Price History Chart DataSkip Price History Chart 1 Day 5 Days 30 Days 90 Days 1 Year Advanced 1 Day 1 Day 5 Days 30 Days 90 Days 1 Year Advanced Show volume Show extended hours Get Vertex Pharmaceuticals alerts:Sign Up Key Stats Today's Range$510.20▼$519.0750-Day Range$470.72▼$557.9652-Week Range$374.17▼$560.25Volume899,601 shsAverage Volume879,500 shsMarket Capitalization$131.05 billionP/E Ratio30.05Dividend YieldN/APrice Target$570.83Consensus RatingModerate Buy Company Overview Vertex Pharmaceuticals Incorporated is a global biotechnology company focused on developing and commercializing medicines for serious diseases. Founded in 1989 and headquartered in Boston, Massachusetts, the company combines research in human genetics with drug discovery and development. Vertex is best known for its cystic fibrosis portfolio, which includes CFTR modulator therapies such as Kalydeco, Orkambi, Symdeko and the combination marketed as Trikafta in the United States and Kaftrio in other markets. These medicines are designed to address the underlying cause of cystic fibrosis for eligible patients with specific genetic mutations. The company has expanded beyond cystic fibrosis through its collaboration with CRISPR Therapeutics on Casgevy, a gene-editing treatment for sickle cell disease and transfusion-dependent beta thalassemia. Vertex also markets Journavx, a non-opioid treatment for moderate to severe acute pain, and continues to develop potential therapies for conditions including type 1 diabetes and kidney disease. Vertex serves patients through commercial operations and partnerships across North America, Europe and other international markets. Reshma Kewalramani has served as the company’s president and chief executive officer since 2017.AI Generated. May Contain Errors. Read More Vertex Pharmaceuticals Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks71st Percentile Overall ScoreVRTX MarketRank™: Vertex Pharmaceuticals scored higher than 71% of companies evaluated by MarketBeat, and ranked 198th out of 900 stocks in the healthcare sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion3.3 / 5Analyst RatingModerate Buy Consensus RatingVertex Pharmaceuticals has received a consensus rating of Moderate Buy. The company's average rating score is 2.96, and is based on 1 strong buy rating, 20 buy ratings, 2 hold ratings, and no sell ratings.Upside PotentialVertex Pharmaceuticals has a consensus price target of $570.83, representing about 10.6% upside from its current price of $516.34.Amount of Analyst CoverageVertex Pharmaceuticals has been the subject of 11 research reports in the past 90 days, demonstrating strong analyst interest in this stock.Read more about Vertex Pharmaceuticals' stock forecast and price target. Earnings and Valuation2.5 / 5Proj. Earnings Growth9.53% Earnings GrowthEarnings for Vertex Pharmaceuticals are expected to grow by 9.53% in the coming year, from $16.69 to $18.28 per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Vertex Pharmaceuticals is 30.05, which means that it is trading at a less expensive P/E ratio than the market average P/E ratio of about 38.97.Price to Earnings Ratio vs. SectorThe P/E ratio of Vertex Pharmaceuticals is 30.05, which means that it is trading at a less expensive P/E ratio than the Healthcare sector average P/E ratio of about 273.31.Price to Earnings Growth RatioVertex Pharmaceuticals has a PEG Ratio of 2.25. PEG Ratios above 1 indicate that a company could be overvalued.Price to Book Value per Share RatioVertex Pharmaceuticals has a P/B Ratio of 7.02. P/B Ratios above 3 indicate that a company could be overvalued with respect to its assets and liabilities.Read more about Vertex Pharmaceuticals' valuation and earnings. Short Interest2.0 / 5Short Interest LevelBearish Percentage of Shares Shorted1.84% of the float of Vertex Pharmaceuticals has been sold short.Short Interest Ratio / Days to CoverVertex Pharmaceuticals has a short interest ratio ("days to cover") of 4.51.Change versus previous monthShort interest in Vertex Pharmaceuticals has recently increased by 12.37%, indicating that investor sentiment is decreasing significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldVertex Pharmaceuticals does not currently pay a dividend.Dividend GrowthVertex Pharmaceuticals does not have a long track record of dividend growth. News and Social Media2.9 / 5News Sentiment0.66 News SentimentVertex Pharmaceuticals has a news sentiment score of 0.66. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.80 average news sentiment score of Healthcare companies.News Coverage This WeekMarketBeat has tracked 25 news articles for Vertex Pharmaceuticals this week, compared to 10 articles on an average week.Search InterestOnly 35 people have searched for VRTX on MarketBeat in the last 30 days. This is a decrease of -15% compared to the previous 30 days.MarketBeat Follows31 people have added Vertex Pharmaceuticals to their MarketBeat watchlist in the last 30 days. This is an increase of 63% compared to the previous 30 days. Company Ownership1.4 / 5Insider TradingSelling Shares Insider Buying vs. Insider SellingIn the past three months, Vertex Pharmaceuticals insiders have sold more of their company's stock than they have bought. Specifically, they have bought $0.00 in company stock and sold $2,346,247.00 in company stock.Percentage Held by Insiders0.20% of the stock of Vertex Pharmaceuticals is held by insiders.Percentage Held by Institutions90.96% of the stock of Vertex Pharmaceuticals is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about Vertex Pharmaceuticals' insider trading history. Receive VRTX Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Vertex Pharmaceuticals and its competitors with MarketBeat's FREE daily newsletter. Submit View SMS TermsSMS is currently available in Australia, Belgium, Canada, France, Germany, Ireland, Italy, New Zealand, the Netherlands, Singapore, South Africa, Spain, Switzerland, the United Kingdom, and the United States. 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VRTX Stock News HeadlinesVertex Pharmaceuticals Incorporated (NASDAQ:VRTX) Given Consensus Rating of "Moderate Buy" by Brokerages3 hours ago | americanbankingnews.comAnalysts Offer Insights on Healthcare Companies: Vertex Pharmaceuticals (VRTX), Ascendis Pharma (ASND) and Charles River Labs (CRL)September 17 at 9:15 AM | theglobeandmail.comGold Miners Post Record Cash Flow Even as Prices Pull BackThe four largest gold miners are generating record free cash flow, even with gold pulling back from recent highs. Margins as high as 75 percent make this the most profitable stretch in their history. Yet junior gold miners, the prime buyout targets for these cash-rich majors, are still priced as if gold were stuck at 1800 dollars an ounce instead of today's levels. Analyst Garrett Goggin calls this the Golden Anomaly, a gap he says rarely lasts long once a gold bull market gets going.September 18 at 1:00 AM | Golden Portfolio (Ad)Vera Makes A Bullish Move — Times Three. Will It Hold Up To Competition?September 15 at 6:21 PM | msn.comWill Vertex’s (VRTX) New CFO Elevation and Digital Focus Reframe Its Capital Allocation Narrative?September 15 at 6:21 PM | finance.yahoo.comVertex Pharmaceuticals (VRTX), Why Is It Getting Fresh Attention Now?September 15 at 6:21 PM | finance.yahoo.comVera Reverses Its Major Chart Upset As Vertex Rivalry Deepens — What Happened?September 15 at 1:20 PM | finance.yahoo.comVertex Partners With World Champion Skier Lindsey Vonn to Raise Awareness of JOURNAVX®, a Non-Opioid Medicine Approved for the Treatment of Moderate-to-Severe Acute PainSeptember 15 at 8:18 AM | finance.yahoo.comSee More Headlines VRTX Stock Analysis - Frequently Asked Questions How have VRTX shares performed this year? Vertex Pharmaceuticals' stock was trading at $453.36 at the beginning of the year. Since then, VRTX shares have increased by 13.9% and is now trading at $516.34. How were Vertex Pharmaceuticals' earnings last quarter? Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) released its quarterly earnings results on Monday, August, 3rd. The pharmaceutical company reported $4.73 EPS for the quarter, missing the consensus estimate of $4.74 by $0.01. The company's revenue was up 12.5% on a year-over-year basis. Read the conference call transcript. Does Vertex Pharmaceuticals have any subsidiaries? Vertex Pharmaceuticals subsidiaries include these companies: V2X, Semma Therapeutics, Exonics Therapeutics, Aurora Biosciences Corporation, The Vertex Foundation Inc., Torreyana Insurance Company Inc., Vertex Farmaceutica do Brasil LTDA, and more. Who are Vertex Pharmaceuticals' major shareholders? Top institutional investors of Vertex Pharmaceuticals include BlackRock Inc. (9.50%), Wellington Management Group LLP (1.28%), UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC (1.22%) and Bank of America Corp DE (1.20%). Insiders that own company stock include Reshma Kewalramani, Stuart A Arbuckle, Amit Sachdev, Ourania Tatsis, Bruce I Sachs, Charles F Wagner Jr, Jeffrey M Leiden, David Altshuler, Joy Liu, Edward Morrow Atkinson III, Carmen Bozic, Jonathan Biller, Duncan Mckechnie, Mark E Bunnage, Kristen Ambrose and Sangeeta N Bhatia. View institutional ownership trends. How do I buy shares of Vertex Pharmaceuticals? Shares of VRTX stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Vertex Pharmaceuticals own? Based on aggregate information from My MarketBeat watchlists, some other companies that Vertex Pharmaceuticals investors own include Salesforce (CRM), Chevron (CVX), Qualcomm (QCOM), AbbVie (ABBV), Home Depot (HD), CocaCola (KO) and Bristol Myers Squibb (BMY). Company Calendar Last Earnings8/03/2026Today9/18/2026Bank of America Global Healthcare Conference9/23/2026Next Earnings (Estimated)11/02/2026Fiscal Year End12/31/2026Get Stock Alerts Health Indicator TradeSmith's Health IndicatorA long-term volatility-based measure designed for securities held 12 months or longer.Green: Strong and healthy uptrend with normal pullbacks.Yellow: Significant pullback but still within expected volatility.Red: Dropped beyond expected volatility; considered unhealthy. Green Zone (3m+) 1-Year History Sep 25 Dec 25 Mar 26 Jun 26 Sep 26 VRTX's financial health is in the Green zone, according to TradeSmith. VRTX has been in this zone for over 3 months. Industry, Sector and Symbol Stock ExchangeNASDAQ SectorHealthcare Industry Biotechnology Sub-IndustryBiotechnology Current SymbolNASDAQ:VRTX CIK875320 Webwww.vrtx.com Phone(617) 341-6100Fax617-576-2109Employees6,400Year Founded1989Price Target and Rating Average Price Target for Vertex Pharmaceuticals$570.83 High Price Target$665.00 Low Price Target$442.00 Potential Upside/Downside+10.6%Consensus RatingModerate Buy Rating Score (0-4)2.96 Research Coverage23 Analysts Profitability EPS (Trailing Twelve Months)$17.18 Trailing P/E Ratio30.05 Forward P/E Ratio30.94 P/E Growth2.25Net Income$3.95 billion Net Margins35.00% Pretax Margin41.90% Return on Equity23.09% Return on Assets16.72% Debt Debt-to-Equity RatioN/A Current Ratio3.19 Quick Ratio2.74 Sales & Book Value Annual Sales$12.59 billion Price / Sales10.41 Cash Flow$17.68 per share Price / Cash Flow29.20 Book Value$73.57 per share Price / Book7.02Miscellaneous Outstanding Shares253,805,000Free Float253,297,000Market Cap$131.05 billion OptionableOptionable Beta0.32 Social Links The Infrastructure's Backbone: 10 Stocks Powering the AI BuildoutThe AI boom extends far beyond the biggest tech names. Discover 10 companies supplying the memory, storage, networking, semiconductor manufacturing, and power infrastructure that make AI possible. Learn where the next wave of AI investment opportunities may emerge—and the key risks investors should watch as the global AI buildout accelerates.Get This Free Report This page (NASDAQ:VRTX) was last updated on 9/18/2026 by MarketBeat.com Staff. From Our PartnersGold Miners Post Record Cash Flow Even as Prices Pull BackThe four largest gold miners are generating record free cash flow, even with gold pulling back from recent hig...Golden Portfolio | SponsoredIran War: Why Is Trump Protecting THEM?A powerful Middle Eastern government is reportedly seeking US intelligence, targeting help, and military prote...Banyan Hill Publishing | SponsoredMusk says UBI is coming. I say it's already here.Elon Musk says AI could make money irrelevant by 2036. 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