Aptevo Therapeutics (APVO) Competitors $0.38 +0.07 (+22.62%) Closing price 05/21/2025 04:00 PM EasternExtended Trading$0.35 -0.03 (-8.16%) As of 06:30 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesOwnershipSEC FilingsShort InterestTrendsBuy This Stock APVO vs. ACXP, BMRA, BCLI, PHIO, BTAI, NEUP, ADXN, SNSE, PRTG, and AIMDShould you be buying Aptevo Therapeutics stock or one of its competitors? The main competitors of Aptevo Therapeutics include Acurx Pharmaceuticals (ACXP), Biomerica (BMRA), Brainstorm Cell Therapeutics (BCLI), Phio Pharmaceuticals (PHIO), BioXcel Therapeutics (BTAI), Neuphoria Therapeutics Inc. - Common Stock (NEUP), Addex Therapeutics (ADXN), Sensei Biotherapeutics (SNSE), Portage Biotech (PRTG), and Ainos (AIMD). These companies are all part of the "pharmaceutical products" industry. Aptevo Therapeutics vs. Acurx Pharmaceuticals Biomerica Brainstorm Cell Therapeutics Phio Pharmaceuticals BioXcel Therapeutics Neuphoria Therapeutics Inc. - Common Stock Addex Therapeutics Sensei Biotherapeutics Portage Biotech Ainos Acurx Pharmaceuticals (NASDAQ:ACXP) and Aptevo Therapeutics (NASDAQ:APVO) are both small-cap medical companies, but which is the better stock? We will contrast the two businesses based on the strength of their earnings, valuation, dividends, community ranking, risk, profitability, media sentiment, analyst recommendations and institutional ownership. Does the MarketBeat Community believe in ACXP or APVO? Aptevo Therapeutics received 182 more outperform votes than Acurx Pharmaceuticals when rated by MarketBeat users. However, 94.44% of users gave Acurx Pharmaceuticals an outperform vote while only 49.75% of users gave Aptevo Therapeutics an outperform vote. CompanyUnderperformOutperformAcurx PharmaceuticalsOutperform Votes1794.44% Underperform Votes15.56%Aptevo TherapeuticsOutperform Votes19949.75% Underperform Votes20150.25% Do institutionals & insiders hold more shares of ACXP or APVO? 11.5% of Acurx Pharmaceuticals shares are held by institutional investors. Comparatively, 8.1% of Aptevo Therapeutics shares are held by institutional investors. 29.6% of Acurx Pharmaceuticals shares are held by insiders. Comparatively, 0.0% of Aptevo Therapeutics shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company will outperform the market over the long term. Is ACXP or APVO more profitable? Acurx Pharmaceuticals' return on equity of -392.36% beat Aptevo Therapeutics' return on equity.Company Net Margins Return on Equity Return on Assets Acurx PharmaceuticalsN/A -392.36% -223.78% Aptevo Therapeutics N/A -488.93%-152.51% Do analysts rate ACXP or APVO? Acurx Pharmaceuticals currently has a consensus target price of $8.00, suggesting a potential upside of 1,846.47%. Aptevo Therapeutics has a consensus target price of $10,952.00, suggesting a potential upside of 2,882,005.26%. Given Aptevo Therapeutics' higher probable upside, analysts plainly believe Aptevo Therapeutics is more favorable than Acurx Pharmaceuticals.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Acurx Pharmaceuticals 0 Sell rating(s) 0 Hold rating(s) 1 Buy rating(s) 0 Strong Buy rating(s) 3.00Aptevo Therapeutics 0 Sell rating(s) 0 Hold rating(s) 1 Buy rating(s) 0 Strong Buy rating(s) 3.00 Does the media favor ACXP or APVO? In the previous week, Acurx Pharmaceuticals had 6 more articles in the media than Aptevo Therapeutics. MarketBeat recorded 8 mentions for Acurx Pharmaceuticals and 2 mentions for Aptevo Therapeutics. Acurx Pharmaceuticals' average media sentiment score of 0.55 beat Aptevo Therapeutics' score of -1.00 indicating that Acurx Pharmaceuticals is being referred to more favorably in the media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Acurx Pharmaceuticals 0 Very Positive mention(s) 0 Positive mention(s) 4 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Aptevo Therapeutics 0 Very Positive mention(s) 0 Positive mention(s) 1 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Negative Which has more risk & volatility, ACXP or APVO? Acurx Pharmaceuticals has a beta of -1.37, suggesting that its stock price is 237% less volatile than the S&P 500. Comparatively, Aptevo Therapeutics has a beta of 6.06, suggesting that its stock price is 506% more volatile than the S&P 500. Which has preferable valuation and earnings, ACXP or APVO? Acurx Pharmaceuticals has higher earnings, but lower revenue than Aptevo Therapeutics. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioAcurx PharmaceuticalsN/AN/A-$14.58M-$0.70-0.59Aptevo Therapeutics$3.11M0.94-$24.13MN/AN/A SummaryAcurx Pharmaceuticals beats Aptevo Therapeutics on 7 of the 12 factors compared between the two stocks. Get Aptevo Therapeutics News Delivered to You Automatically Sign up to receive the latest news and ratings for APVO and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding {thisCompany.Symbol} and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart APVO vs. The Competition Export to ExcelMetricAptevo TherapeuticsPharmaceutical IndustryMedical SectorNASDAQ ExchangeMarket Cap$2.92M$6.48B$5.35B$8.38BDividend YieldN/A2.66%5.22%4.10%P/E RatioN/A8.9226.8419.71Price / Sales0.94250.96391.39116.98Price / CashN/A65.8538.2534.62Price / Book0.126.466.794.50Net Income-$24.13M$143.98M$3.23B$248.18M7 Day Performance15.15%3.04%4.07%1.14%1 Month Performance-40.22%7.44%12.52%15.20%1 Year Performance-99.96%-2.46%16.83%6.56% Aptevo Therapeutics Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)APVOAptevo Therapeutics2.1258 of 5 stars$0.38+22.6%$10,952.00+2,882,005.3%-100.0%$2.92M$3.11M0.0050Negative NewsEarnings ReportHigh Trading VolumeACXPAcurx Pharmaceuticals2.5712 of 5 stars$0.41+4.7%$8.00+1,874.8%-85.3%$9.51MN/A-0.373Analyst RevisionHigh Trading VolumeBMRABiomerica0.1439 of 5 stars$3.60-1.1%N/A-33.3%$9.17M$5.68M-10.5960BCLIBrainstorm Cell Therapeutics3.9683 of 5 stars$1.36+3.0%$30.00+2,105.9%-87.3%$8.87MN/A-0.2840Earnings ReportAnalyst ForecastGap UpHigh Trading VolumePHIOPhio Pharmaceuticals3.0867 of 5 stars$1.83-0.5%$4.00+118.6%-73.8%$8.74MN/A-0.1710Positive NewsBTAIBioXcel Therapeutics3.9462 of 5 stars$1.44-0.7%$42.60+2,858.3%-95.7%$8.72M$1.85M-0.0490NEUPNeuphoria Therapeutics Inc. - Common Stock1.5429 of 5 stars$4.92flat$21.00+326.8%N/A$8.64M$662,715.000.00N/ANews CoverageEarnings ReportADXNAddex Therapeutics1.6667 of 5 stars$8.10-0.3%$30.00+270.6%-5.6%$8.58M$556,045.00-23.8130Gap UpSNSESensei Biotherapeutics3.9197 of 5 stars$0.33-4.1%$4.25+1,187.9%-77.1%$8.32MN/A-0.2840PRTGPortage Biotech0.2925 of 5 stars$7.99+1.3%N/A+61.1%$8.28MN/A-0.196Gap DownAIMDAinos0.4752 of 5 stars$0.53-2.9%N/A-51.6%$8.15M$20,729.00-0.4140Gap Down Related Companies and Tools Related Companies ACXP Alternatives BMRA Alternatives BCLI Alternatives PHIO Alternatives BTAI Alternatives NEUP Alternatives ADXN Alternatives SNSE Alternatives PRTG Alternatives AIMD Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:APVO) was last updated on 5/22/2025 by MarketBeat.com Staff From Our PartnersJuly 2025 Rule Change to Impact Retirement InvestorsThere's a massive change from a new rule going into effect this July. 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