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Aptevo Therapeutics (APVO) Competitors

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$2.42 +0.06 (+2.32%)
As of 10:44 AM Eastern
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APVO vs. PLUR, KTTA, NCEL, TPST, and BIVI

Should you buy Aptevo Therapeutics stock or one of its competitors? Aptevo Therapeutics's main competitors and comparable companies include Pluri (PLUR), Pasithea Therapeutics (KTTA), NLS Pharmaceutics (NCEL), Tempest Therapeutics (TPST), and BioVie (BIVI). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Aptevo Therapeutics compare to Pluri?

Aptevo Therapeutics (NASDAQ:APVO) and Pluri (NASDAQ:PLUR) are both small-cap healthcare companies, but which is the superior stock? We will compare the two companies based on the strength of their media sentiment, risk, institutional ownership, valuation, profitability, dividends, earnings and analyst recommendations.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Aptevo Therapeutics
1 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
1 Strong Buy rating(s)
2.33
Pluri
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00

8.1% of Aptevo Therapeutics shares are owned by institutional investors. Comparatively, 16.6% of Pluri shares are owned by institutional investors. 0.5% of Aptevo Therapeutics shares are owned by company insiders. Comparatively, 43.2% of Pluri shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term.

Pluri has higher revenue and earnings than Aptevo Therapeutics. Pluri is trading at a lower price-to-earnings ratio than Aptevo Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Aptevo TherapeuticsN/AN/A-$25.97M-$51.83N/A
Pluri$1.08M15.05-$22.58M-$4.53N/A

Aptevo Therapeutics has a beta of 1.65, meaning that its stock price is 65% more volatile than the broader market. Comparatively, Pluri has a beta of 0.67, meaning that its stock price is 33% less volatile than the broader market.

In the previous week, Pluri had 2 more articles in the media than Aptevo Therapeutics. MarketBeat recorded 4 mentions for Pluri and 2 mentions for Aptevo Therapeutics. Aptevo Therapeutics' average media sentiment score of 0.93 beat Pluri's score of 0.81 indicating that Aptevo Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Aptevo Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Pluri
1 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Aptevo Therapeutics has a net margin of 0.00% compared to Pluri's net margin of -2,162.08%. Pluri's return on equity of 0.00% beat Aptevo Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Aptevo TherapeuticsN/A -201.49% -119.21%
Pluri -2,162.08%N/A -106.59%

Summary

Pluri beats Aptevo Therapeutics on 8 of the 14 factors compared between the two stocks.

How does Aptevo Therapeutics compare to Pasithea Therapeutics?

Aptevo Therapeutics (NASDAQ:APVO) and Pasithea Therapeutics (NASDAQ:KTTA) are both small-cap healthcare companies, but which is the superior business? We will contrast the two businesses based on the strength of their institutional ownership, profitability, analyst recommendations, media sentiment, earnings, risk, valuation and dividends.

8.1% of Aptevo Therapeutics shares are held by institutional investors. Comparatively, 23.9% of Pasithea Therapeutics shares are held by institutional investors. 0.5% of Aptevo Therapeutics shares are held by insiders. Comparatively, 1.5% of Pasithea Therapeutics shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a stock is poised for long-term growth.

Pasithea Therapeutics is trading at a lower price-to-earnings ratio than Aptevo Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Aptevo TherapeuticsN/AN/A-$25.97M-$51.83N/A
Pasithea TherapeuticsN/AN/A-$20.43M-$1.58N/A

Pasithea Therapeutics has a consensus target price of $3.00, suggesting a potential upside of 436.67%. Given Pasithea Therapeutics' higher probable upside, analysts plainly believe Pasithea Therapeutics is more favorable than Aptevo Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Aptevo Therapeutics
1 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
1 Strong Buy rating(s)
2.33
Pasithea Therapeutics
1 Sell rating(s)
1 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00

In the previous week, Aptevo Therapeutics had 1 more articles in the media than Pasithea Therapeutics. MarketBeat recorded 2 mentions for Aptevo Therapeutics and 1 mentions for Pasithea Therapeutics. Pasithea Therapeutics' average media sentiment score of 1.89 beat Aptevo Therapeutics' score of 0.93 indicating that Pasithea Therapeutics is being referred to more favorably in the news media.

Company Overall Sentiment
Aptevo Therapeutics Positive
Pasithea Therapeutics Very Positive

Aptevo Therapeutics has a beta of 1.65, indicating that its share price is 65% more volatile than the broader market. Comparatively, Pasithea Therapeutics has a beta of 0.29, indicating that its share price is 71% less volatile than the broader market.

Pasithea Therapeutics' return on equity of -49.49% beat Aptevo Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Aptevo TherapeuticsN/A -201.49% -119.21%
Pasithea Therapeutics N/A -49.49%-46.81%

Summary

Pasithea Therapeutics beats Aptevo Therapeutics on 9 of the 14 factors compared between the two stocks.

How does Aptevo Therapeutics compare to NLS Pharmaceutics?

Aptevo Therapeutics (NASDAQ:APVO) and NLS Pharmaceutics (NASDAQ:NCEL) are both small-cap healthcare companies, but which is the better investment? We will contrast the two businesses based on the strength of their analyst recommendations, valuation, earnings, media sentiment, profitability, dividends, risk and institutional ownership.

NLS Pharmaceutics' return on equity of 0.00% beat Aptevo Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Aptevo TherapeuticsN/A -201.49% -119.21%
NLS Pharmaceutics N/A N/A N/A

8.1% of Aptevo Therapeutics shares are held by institutional investors. 0.5% of Aptevo Therapeutics shares are held by insiders. Comparatively, 16.4% of NLS Pharmaceutics shares are held by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

NLS Pharmaceutics has a consensus target price of $23.00, suggesting a potential upside of 578.47%. Given NLS Pharmaceutics' higher probable upside, analysts clearly believe NLS Pharmaceutics is more favorable than Aptevo Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Aptevo Therapeutics
1 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
1 Strong Buy rating(s)
2.33
NLS Pharmaceutics
1 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Aptevo TherapeuticsN/AN/A-$25.97M-$51.83N/A
NLS PharmaceuticsN/AN/A-$8.30MN/AN/A

In the previous week, Aptevo Therapeutics and Aptevo Therapeutics both had 2 articles in the media. NLS Pharmaceutics' average media sentiment score of 0.94 beat Aptevo Therapeutics' score of 0.93 indicating that NLS Pharmaceutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Aptevo Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
NLS Pharmaceutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Aptevo Therapeutics has a beta of 1.65, suggesting that its share price is 65% more volatile than the broader market. Comparatively, NLS Pharmaceutics has a beta of 0.94, suggesting that its share price is 6% less volatile than the broader market.

Summary

NLS Pharmaceutics beats Aptevo Therapeutics on 7 of the 11 factors compared between the two stocks.

How does Aptevo Therapeutics compare to Tempest Therapeutics?

Aptevo Therapeutics (NASDAQ:APVO) and Tempest Therapeutics (NASDAQ:TPST) are both small-cap healthcare companies, but which is the superior investment? We will contrast the two companies based on the strength of their profitability, dividends, institutional ownership, earnings, analyst recommendations, risk, valuation and media sentiment.

Aptevo Therapeutics has a beta of 1.65, suggesting that its stock price is 65% more volatile than the broader market. Comparatively, Tempest Therapeutics has a beta of -1.72, suggesting that its stock price is 272% less volatile than the broader market.

8.1% of Aptevo Therapeutics shares are held by institutional investors. Comparatively, 22.5% of Tempest Therapeutics shares are held by institutional investors. 0.5% of Aptevo Therapeutics shares are held by insiders. Comparatively, 36.2% of Tempest Therapeutics shares are held by insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company is poised for long-term growth.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Aptevo Therapeutics
1 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
1 Strong Buy rating(s)
2.33
Tempest Therapeutics
1 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.50

Aptevo Therapeutics' return on equity of -201.49% beat Tempest Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Aptevo TherapeuticsN/A -201.49% -119.21%
Tempest Therapeutics N/A -576.56%-134.99%

Tempest Therapeutics is trading at a lower price-to-earnings ratio than Aptevo Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Aptevo TherapeuticsN/AN/A-$25.97M-$51.83N/A
Tempest TherapeuticsN/AN/A-$26.26M-$4.28N/A

In the previous week, Aptevo Therapeutics had 1 more articles in the media than Tempest Therapeutics. MarketBeat recorded 2 mentions for Aptevo Therapeutics and 1 mentions for Tempest Therapeutics. Tempest Therapeutics' average media sentiment score of 1.89 beat Aptevo Therapeutics' score of 0.93 indicating that Tempest Therapeutics is being referred to more favorably in the news media.

Company Overall Sentiment
Aptevo Therapeutics Positive
Tempest Therapeutics Very Positive

Summary

Aptevo Therapeutics beats Tempest Therapeutics on 8 of the 12 factors compared between the two stocks.

How does Aptevo Therapeutics compare to BioVie?

BioVie (NASDAQ:BIVI) and Aptevo Therapeutics (NASDAQ:APVO) are both small-cap healthcare companies, but which is the superior business? We will compare the two companies based on the strength of their risk, analyst recommendations, valuation, profitability, dividends, earnings, media sentiment and institutional ownership.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
BioVie
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00
Aptevo Therapeutics
1 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
1 Strong Buy rating(s)
2.33

BioVie's return on equity of -126.02% beat Aptevo Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
BioVieN/A -126.02% -108.88%
Aptevo Therapeutics N/A -201.49%-119.21%

BioVie has a beta of 0.6, meaning that its share price is 40% less volatile than the broader market. Comparatively, Aptevo Therapeutics has a beta of 1.65, meaning that its share price is 65% more volatile than the broader market.

In the previous week, BioVie had 7 more articles in the media than Aptevo Therapeutics. MarketBeat recorded 9 mentions for BioVie and 2 mentions for Aptevo Therapeutics. BioVie's average media sentiment score of 0.97 beat Aptevo Therapeutics' score of 0.93 indicating that BioVie is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
BioVie
1 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Aptevo Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

4.6% of BioVie shares are owned by institutional investors. Comparatively, 8.1% of Aptevo Therapeutics shares are owned by institutional investors. 0.9% of BioVie shares are owned by insiders. Comparatively, 0.5% of Aptevo Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

BioVie is trading at a lower price-to-earnings ratio than Aptevo Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
BioVieN/AN/A-$22.07M-$3.15N/A
Aptevo TherapeuticsN/AN/A-$25.97M-$51.83N/A

Summary

BioVie beats Aptevo Therapeutics on 7 of the 12 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding APVO and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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APVO vs. The Competition

MetricAptevo TherapeuticsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$4.39M$3.90B$7.10B$12.83B
Dividend YieldN/A3.61%2.54%11.27%
P/E Ratio-0.0511.65273.0425.49
Price / SalesN/A1,396.25686.65123.03
Price / CashN/A44.0628.7436.03
Price / Book0.1416.7411.026.35
Net Income-$25.97M-$22.71M$3.47B$349.46M
7 Day Performance0.62%2.39%1.03%-0.11%
1 Month Performance-41.00%12.62%8.03%4.32%
1 Year Performance-91.79%53.90%23.72%14.79%

Aptevo Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
APVO
Aptevo Therapeutics
1.4583 of 5 stars
$2.43
+2.3%
N/A-92.0%$4.39MN/AN/A50
PLUR
Pluri
0.9142 of 5 stars
$1.71
-3.4%
N/A-71.0%$18.45M$1.34MN/A150
KTTA
Pasithea Therapeutics
3.3629 of 5 stars
$0.54
+14.8%
$3.00
+456.2%
-30.7%$18.02MN/AN/A3
NCEL
NLS Pharmaceutics
2.5814 of 5 stars
$3.26
-3.3%
$23.00
+605.5%
-85.0%$17.44MN/AN/A6
TPST
Tempest Therapeutics
1.3386 of 5 stars
$1.04
+2.0%
N/A-89.3%$16.62MN/AN/A20

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This page (NASDAQ:APVO) was last updated on 8/31/2026 by MarketBeat.com Staff.
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