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Aptevo Therapeutics (APVO) Competitors

Aptevo Therapeutics logo
$1.84 0.00 (0.00%)
Closing price 09/18/2026 04:00 PM Eastern
Extended Trading
$1.88 +0.04 (+2.17%)
As of 09/18/2026 07:42 PM Eastern
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APVO vs. PLUR, NRSN, SQZ, BCLI, and BLRX

Should you buy Aptevo Therapeutics stock or one of its competitors? Aptevo Therapeutics's main competitors and comparable companies include Pluri (PLUR), NeuroSense Therapeutics (NRSN), SQZ Biotechnologies (SQZ), Brainstorm Cell Therapeutics (BCLI), and BioLineRx (BLRX). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "biotechnology" industry.

How does Aptevo Therapeutics compare to Pluri?

Aptevo Therapeutics (NASDAQ:APVO) and Pluri (NASDAQ:PLUR) are both small-cap healthcare companies, but which is the superior business? We will compare the two companies based on the strength of their media sentiment, dividends, earnings, institutional ownership, risk, profitability, valuation and analyst recommendations.

In the previous week, Aptevo Therapeutics and Aptevo Therapeutics both had 1 articles in the media. Aptevo Therapeutics' average media sentiment score of 0.75 beat Pluri's score of 0.00 indicating that Aptevo Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Aptevo Therapeutics
0 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Pluri
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Aptevo Therapeutics has a net margin of 0.00% compared to Pluri's net margin of -2,344.59%. Pluri's return on equity of 0.00% beat Aptevo Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Aptevo TherapeuticsN/A -201.49% -119.21%
Pluri -2,344.59%N/A -82.71%

8.1% of Aptevo Therapeutics shares are owned by institutional investors. Comparatively, 16.6% of Pluri shares are owned by institutional investors. 0.4% of Aptevo Therapeutics shares are owned by company insiders. Comparatively, 43.2% of Pluri shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth.

Pluri has higher revenue and earnings than Aptevo Therapeutics. Pluri is trading at a lower price-to-earnings ratio than Aptevo Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Aptevo TherapeuticsN/AN/A-$25.97M-$51.83N/A
Pluri$1.02M13.08-$23.82M-$2.45N/A

Aptevo Therapeutics has a beta of 1.6, meaning that its share price is 60% more volatile than the broader market. Comparatively, Pluri has a beta of 0.68, meaning that its share price is 32% less volatile than the broader market.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Aptevo Therapeutics
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00
Pluri
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00

Summary

Pluri beats Aptevo Therapeutics on 7 of the 11 factors compared between the two stocks.

How does Aptevo Therapeutics compare to NeuroSense Therapeutics?

Aptevo Therapeutics (NASDAQ:APVO) and NeuroSense Therapeutics (NASDAQ:NRSN) are both small-cap healthcare companies, but which is the better stock? We will contrast the two companies based on the strength of their valuation, risk, earnings, institutional ownership, media sentiment, profitability, dividends and analyst recommendations.

NeuroSense Therapeutics is trading at a lower price-to-earnings ratio than Aptevo Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Aptevo TherapeuticsN/AN/A-$25.97M-$51.83N/A
NeuroSense TherapeuticsN/AN/A-$11.12M-$0.54N/A

NeuroSense Therapeutics' return on equity of 0.00% beat Aptevo Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Aptevo TherapeuticsN/A -201.49% -119.21%
NeuroSense Therapeutics N/A N/A N/A

NeuroSense Therapeutics has a consensus price target of $170.00, indicating a potential upside of 2,577.17%. Given NeuroSense Therapeutics' stronger consensus rating and higher possible upside, analysts plainly believe NeuroSense Therapeutics is more favorable than Aptevo Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Aptevo Therapeutics
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00
NeuroSense Therapeutics
1 Sell rating(s)
1 Hold rating(s)
3 Buy rating(s)
1 Strong Buy rating(s)
2.67

8.1% of Aptevo Therapeutics shares are owned by institutional investors. Comparatively, 1.0% of NeuroSense Therapeutics shares are owned by institutional investors. 0.4% of Aptevo Therapeutics shares are owned by company insiders. Comparatively, 27.4% of NeuroSense Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock is poised for long-term growth.

Aptevo Therapeutics has a beta of 1.6, meaning that its share price is 60% more volatile than the broader market. Comparatively, NeuroSense Therapeutics has a beta of 1.6, meaning that its share price is 60% more volatile than the broader market.

In the previous week, Aptevo Therapeutics and Aptevo Therapeutics both had 1 articles in the media. Aptevo Therapeutics' average media sentiment score of 0.75 beat NeuroSense Therapeutics' score of 0.00 indicating that Aptevo Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Aptevo Therapeutics
0 Very Positive mention(s)
1 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
NeuroSense Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Summary

NeuroSense Therapeutics beats Aptevo Therapeutics on 9 of the 12 factors compared between the two stocks.

How does Aptevo Therapeutics compare to SQZ Biotechnologies?

SQZ Biotechnologies (NYSE:SQZ) and Aptevo Therapeutics (NASDAQ:APVO) are both small-cap healthcare companies, but which is the better business? We will contrast the two businesses based on the strength of their analyst recommendations, profitability, institutional ownership, risk, dividends, media sentiment, valuation and earnings.

Aptevo Therapeutics has a net margin of 0.00% compared to SQZ Biotechnologies' net margin of -369.96%. SQZ Biotechnologies' return on equity of -119.83% beat Aptevo Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
SQZ Biotechnologies-369.96% -119.83% -59.90%
Aptevo Therapeutics N/A -201.49%-119.21%

Aptevo Therapeutics has lower revenue, but higher earnings than SQZ Biotechnologies. Aptevo Therapeutics is trading at a lower price-to-earnings ratio than SQZ Biotechnologies, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
SQZ Biotechnologies$18.16M0.04-$79.46M-$2.61N/A
Aptevo TherapeuticsN/AN/A-$25.97M-$51.83N/A

SQZ Biotechnologies has a beta of 2.34, meaning that its stock price is 134% more volatile than the broader market. Comparatively, Aptevo Therapeutics has a beta of 1.6, meaning that its stock price is 60% more volatile than the broader market.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
SQZ Biotechnologies
0 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
0.00
Aptevo Therapeutics
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00

38.5% of SQZ Biotechnologies shares are held by institutional investors. Comparatively, 8.1% of Aptevo Therapeutics shares are held by institutional investors. 16.0% of SQZ Biotechnologies shares are held by company insiders. Comparatively, 0.4% of Aptevo Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a stock will outperform the market over the long term.

In the previous week, Aptevo Therapeutics had 1 more articles in the media than SQZ Biotechnologies. MarketBeat recorded 1 mentions for Aptevo Therapeutics and 0 mentions for SQZ Biotechnologies. Aptevo Therapeutics' average media sentiment score of 0.75 beat SQZ Biotechnologies' score of 0.00 indicating that Aptevo Therapeutics is being referred to more favorably in the news media.

Company Overall Sentiment
SQZ Biotechnologies Neutral
Aptevo Therapeutics Positive

Summary

SQZ Biotechnologies beats Aptevo Therapeutics on 8 of the 13 factors compared between the two stocks.

How does Aptevo Therapeutics compare to Brainstorm Cell Therapeutics?

Aptevo Therapeutics (NASDAQ:APVO) and Brainstorm Cell Therapeutics (NASDAQ:BCLI) are both small-cap healthcare companies, but which is the superior business? We will contrast the two businesses based on the strength of their analyst recommendations, profitability, risk, institutional ownership, valuation, dividends, media sentiment and earnings.

Aptevo Therapeutics has a beta of 1.6, meaning that its share price is 60% more volatile than the broader market. Comparatively, Brainstorm Cell Therapeutics has a beta of 0.28, meaning that its share price is 72% less volatile than the broader market.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Aptevo Therapeutics
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00
Brainstorm Cell Therapeutics
0 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
0.00

Brainstorm Cell Therapeutics' return on equity of 0.00% beat Aptevo Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Aptevo TherapeuticsN/A -201.49% -119.21%
Brainstorm Cell Therapeutics N/A N/A -519.50%

8.1% of Aptevo Therapeutics shares are held by institutional investors. Comparatively, 14.3% of Brainstorm Cell Therapeutics shares are held by institutional investors. 0.4% of Aptevo Therapeutics shares are held by insiders. Comparatively, 11.2% of Brainstorm Cell Therapeutics shares are held by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Brainstorm Cell Therapeutics is trading at a lower price-to-earnings ratio than Aptevo Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Aptevo TherapeuticsN/AN/A-$25.97M-$51.83N/A
Brainstorm Cell TherapeuticsN/AN/A-$11.62M-$1.65N/A

In the previous week, Aptevo Therapeutics had 1 more articles in the media than Brainstorm Cell Therapeutics. MarketBeat recorded 1 mentions for Aptevo Therapeutics and 0 mentions for Brainstorm Cell Therapeutics. Aptevo Therapeutics' average media sentiment score of 0.75 beat Brainstorm Cell Therapeutics' score of 0.00 indicating that Aptevo Therapeutics is being referred to more favorably in the media.

Company Overall Sentiment
Aptevo Therapeutics Positive
Brainstorm Cell Therapeutics Neutral

Summary

Aptevo Therapeutics beats Brainstorm Cell Therapeutics on 6 of the 11 factors compared between the two stocks.

How does Aptevo Therapeutics compare to BioLineRx?

BioLineRx (NASDAQ:BLRX) and Aptevo Therapeutics (NASDAQ:APVO) are both small-cap healthcare companies, but which is the better investment? We will contrast the two businesses based on the strength of their valuation, dividends, institutional ownership, risk, media sentiment, profitability, analyst recommendations and earnings.

In the previous week, Aptevo Therapeutics had 1 more articles in the media than BioLineRx. MarketBeat recorded 1 mentions for Aptevo Therapeutics and 0 mentions for BioLineRx. Aptevo Therapeutics' average media sentiment score of 0.75 beat BioLineRx's score of 0.00 indicating that Aptevo Therapeutics is being referred to more favorably in the news media.

Company Overall Sentiment
BioLineRx Neutral
Aptevo Therapeutics Positive

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
BioLineRx
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00
Aptevo Therapeutics
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00

BioLineRx has higher revenue and earnings than Aptevo Therapeutics. BioLineRx is trading at a lower price-to-earnings ratio than Aptevo Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
BioLineRx$1.18M10.23-$1.17M-$1.69N/A
Aptevo TherapeuticsN/AN/A-$25.97M-$51.83N/A

1.6% of BioLineRx shares are owned by institutional investors. Comparatively, 8.1% of Aptevo Therapeutics shares are owned by institutional investors. 1.1% of BioLineRx shares are owned by insiders. Comparatively, 0.4% of Aptevo Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth.

Aptevo Therapeutics has a net margin of 0.00% compared to BioLineRx's net margin of -502.08%. BioLineRx's return on equity of -34.80% beat Aptevo Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
BioLineRx-502.08% -34.80% -18.27%
Aptevo Therapeutics N/A -201.49%-119.21%

BioLineRx has a beta of 1.56, suggesting that its share price is 56% more volatile than the broader market. Comparatively, Aptevo Therapeutics has a beta of 1.6, suggesting that its share price is 60% more volatile than the broader market.

Summary

BioLineRx and Aptevo Therapeutics tied by winning 6 of the 12 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding APVO and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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APVO vs. The Competition

MetricAptevo TherapeuticsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$3.33M$3.88B$7.24B$12.95B
Dividend YieldN/A3.64%2.57%12.80%
P/E Ratio-0.0414.23275.4925.40
Price / SalesN/A1,440.84644.4486.30
Price / CashN/A108.9076.2551.42
Price / Book0.1115.4510.466.33
Net Income-$25.97M-$22.86M$3.49B$358.33M
7 Day Performance1.10%-1.21%0.59%1.12%
1 Month Performance-33.33%-3.29%-1.74%-2.39%
1 Year Performance-94.19%37.74%18.13%5.35%

Aptevo Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
APVO
Aptevo Therapeutics
0.743 of 5 stars
$1.84
flat
N/A-94.2%$3.33MN/AN/A33
PLUR
Pluri
0.2399 of 5 stars
$1.18
-5.6%
N/A-77.5%$13.15M$1.34MN/A150
NRSN
NeuroSense Therapeutics
2.1704 of 5 stars
$0.35
+4.6%
$8.50
+2,348.2%
-74.0%$13.11MN/AN/A10
SQZ
SQZ Biotechnologies
N/A$0.02
flat
N/AN/A$12.83M$18.16MN/A1,620
BCLI
Brainstorm Cell Therapeutics
N/A$1.08
+4.9%
N/A+28.7%$12.29MN/AN/A40

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This page (NASDAQ:APVO) was last updated on 9/20/2026 by MarketBeat.com Staff.
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