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Aptevo Therapeutics (APVO) Competitors

Aptevo Therapeutics logo
$4.12 -0.06 (-1.44%)
As of 12:24 PM Eastern
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APVO vs. SKYE, ALLR, MRKR, NCEL, and QNTM

Should you buy Aptevo Therapeutics stock or one of its competitors? MarketBeat compares Aptevo Therapeutics with other companies and stocks that may be similar based on industry, sector, market capitalization, business model, investor interest, or shared news coverage. Companies and stocks commonly compared with Aptevo Therapeutics include Skye Bioscience (SKYE), Allarity Therapeutics (ALLR), Marker Therapeutics (MRKR), NLS Pharmaceutics (NCEL), and Quantum Biopharma (QNTM). These companies are all part of the "biotechnology" industry.

How does Aptevo Therapeutics compare to Skye Bioscience?

Skye Bioscience (NASDAQ:SKYE) and Aptevo Therapeutics (NASDAQ:APVO) are both small-cap healthcare companies, but which is the superior stock? We will contrast the two businesses based on the strength of their risk, institutional ownership, dividends, profitability, media sentiment, analyst recommendations, earnings and valuation.

21.1% of Skye Bioscience shares are owned by institutional investors. Comparatively, 8.1% of Aptevo Therapeutics shares are owned by institutional investors. 6.2% of Skye Bioscience shares are owned by insiders. Comparatively, 0.5% of Aptevo Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term.

Skye Bioscience has a beta of 2.97, meaning that its stock price is 197% more volatile than the broader market. Comparatively, Aptevo Therapeutics has a beta of 1.65, meaning that its stock price is 65% more volatile than the broader market.

Skye Bioscience is trading at a lower price-to-earnings ratio than Aptevo Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Skye BioscienceN/AN/A-$55.92M-$1.44N/A
Aptevo TherapeuticsN/AN/A-$25.97M-$197.60N/A

In the previous week, Skye Bioscience had 1 more articles in the media than Aptevo Therapeutics. MarketBeat recorded 2 mentions for Skye Bioscience and 1 mentions for Aptevo Therapeutics. Skye Bioscience's average media sentiment score of 0.37 beat Aptevo Therapeutics' score of 0.00 indicating that Skye Bioscience is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Skye Bioscience
0 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Aptevo Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Aptevo Therapeutics' return on equity of -198.50% beat Skye Bioscience's return on equity.

Company Net Margins Return on Equity Return on Assets
Skye BioscienceN/A -217.27% -162.39%
Aptevo Therapeutics N/A -198.50%-117.06%

Skye Bioscience presently has a consensus price target of $8.50, indicating a potential upside of 1,491.76%. Given Skye Bioscience's stronger consensus rating and higher probable upside, equities analysts plainly believe Skye Bioscience is more favorable than Aptevo Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Skye Bioscience
1 Sell rating(s)
2 Hold rating(s)
2 Buy rating(s)
1 Strong Buy rating(s)
2.50
Aptevo Therapeutics
1 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
1 Strong Buy rating(s)
2.33

Summary

Skye Bioscience beats Aptevo Therapeutics on 9 of the 13 factors compared between the two stocks.

How does Aptevo Therapeutics compare to Allarity Therapeutics?

Allarity Therapeutics (NASDAQ:ALLR) and Aptevo Therapeutics (NASDAQ:APVO) are both small-cap healthcare companies, but which is the superior stock? We will compare the two companies based on the strength of their analyst recommendations, valuation, dividends, media sentiment, institutional ownership, profitability, earnings and risk.

Allarity Therapeutics currently has a consensus target price of $10.25, suggesting a potential upside of 630.06%. Given Allarity Therapeutics' higher probable upside, equities research analysts plainly believe Allarity Therapeutics is more favorable than Aptevo Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Allarity Therapeutics
1 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00
Aptevo Therapeutics
1 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
1 Strong Buy rating(s)
2.33

Allarity Therapeutics' return on equity of -109.94% beat Aptevo Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Allarity TherapeuticsN/A -109.94% -47.27%
Aptevo Therapeutics N/A -198.50%-117.06%

Allarity Therapeutics has higher revenue and earnings than Aptevo Therapeutics. Allarity Therapeutics is trading at a lower price-to-earnings ratio than Aptevo Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Allarity Therapeutics$320K69.81-$11.23M-$0.72N/A
Aptevo TherapeuticsN/AN/A-$25.97M-$197.60N/A

11.5% of Allarity Therapeutics shares are held by institutional investors. Comparatively, 8.1% of Aptevo Therapeutics shares are held by institutional investors. 0.2% of Allarity Therapeutics shares are held by company insiders. Comparatively, 0.5% of Aptevo Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

Allarity Therapeutics has a beta of 0.51, indicating that its share price is 49% less volatile than the broader market. Comparatively, Aptevo Therapeutics has a beta of 1.65, indicating that its share price is 65% more volatile than the broader market.

In the previous week, Aptevo Therapeutics had 1 more articles in the media than Allarity Therapeutics. MarketBeat recorded 1 mentions for Aptevo Therapeutics and 0 mentions for Allarity Therapeutics. Allarity Therapeutics' average media sentiment score of 0.00 equaled Aptevo Therapeutics'average media sentiment score.

Company Overall Sentiment
Allarity Therapeutics Neutral
Aptevo Therapeutics Neutral

Summary

Allarity Therapeutics beats Aptevo Therapeutics on 8 of the 14 factors compared between the two stocks.

How does Aptevo Therapeutics compare to Marker Therapeutics?

Marker Therapeutics (NASDAQ:MRKR) and Aptevo Therapeutics (NASDAQ:APVO) are both small-cap healthcare companies, but which is the better business? We will compare the two companies based on the strength of their profitability, institutional ownership, valuation, risk, analyst recommendations, media sentiment, earnings and dividends.

Aptevo Therapeutics has a net margin of 0.00% compared to Marker Therapeutics' net margin of -343.03%. Marker Therapeutics' return on equity of -73.29% beat Aptevo Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Marker Therapeutics-343.03% -73.29% -59.70%
Aptevo Therapeutics N/A -198.50%-117.06%

Marker Therapeutics has a beta of 1.5, indicating that its stock price is 50% more volatile than the broader market. Comparatively, Aptevo Therapeutics has a beta of 1.65, indicating that its stock price is 65% more volatile than the broader market.

22.4% of Marker Therapeutics shares are held by institutional investors. Comparatively, 8.1% of Aptevo Therapeutics shares are held by institutional investors. 5.7% of Marker Therapeutics shares are held by company insiders. Comparatively, 0.5% of Aptevo Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.

In the previous week, Aptevo Therapeutics had 1 more articles in the media than Marker Therapeutics. MarketBeat recorded 1 mentions for Aptevo Therapeutics and 0 mentions for Marker Therapeutics. Marker Therapeutics' average media sentiment score of 0.00 equaled Aptevo Therapeutics'average media sentiment score.

Company Overall Sentiment
Marker Therapeutics Neutral
Aptevo Therapeutics Neutral

Marker Therapeutics presently has a consensus target price of $10.00, indicating a potential upside of 788.89%. Given Marker Therapeutics' higher probable upside, research analysts plainly believe Marker Therapeutics is more favorable than Aptevo Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Marker Therapeutics
1 Sell rating(s)
1 Hold rating(s)
2 Buy rating(s)
0 Strong Buy rating(s)
2.25
Aptevo Therapeutics
1 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
1 Strong Buy rating(s)
2.33

Marker Therapeutics has higher revenue and earnings than Aptevo Therapeutics. Marker Therapeutics is trading at a lower price-to-earnings ratio than Aptevo Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Marker Therapeutics$3.55M5.28-$12.16M-$0.61N/A
Aptevo TherapeuticsN/AN/A-$25.97M-$197.60N/A

Summary

Marker Therapeutics beats Aptevo Therapeutics on 9 of the 15 factors compared between the two stocks.

How does Aptevo Therapeutics compare to NLS Pharmaceutics?

NLS Pharmaceutics (NASDAQ:NCEL) and Aptevo Therapeutics (NASDAQ:APVO) are both small-cap healthcare companies, but which is the superior business? We will contrast the two companies based on the strength of their risk, dividends, profitability, media sentiment, valuation, institutional ownership, earnings and analyst recommendations.

NLS Pharmaceutics currently has a consensus target price of $23.00, indicating a potential upside of 621.00%. Given NLS Pharmaceutics' higher probable upside, research analysts clearly believe NLS Pharmaceutics is more favorable than Aptevo Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
NLS Pharmaceutics
1 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00
Aptevo Therapeutics
1 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
1 Strong Buy rating(s)
2.33

In the previous week, Aptevo Therapeutics had 1 more articles in the media than NLS Pharmaceutics. MarketBeat recorded 1 mentions for Aptevo Therapeutics and 0 mentions for NLS Pharmaceutics. NLS Pharmaceutics' average media sentiment score of 0.00 equaled Aptevo Therapeutics'average media sentiment score.

Company Overall Sentiment
NLS Pharmaceutics Neutral
Aptevo Therapeutics Neutral

8.1% of Aptevo Therapeutics shares are owned by institutional investors. 16.4% of NLS Pharmaceutics shares are owned by insiders. Comparatively, 0.5% of Aptevo Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
NLS PharmaceuticsN/AN/A-$8.30MN/AN/A
Aptevo TherapeuticsN/AN/A-$25.97M-$197.60N/A

NLS Pharmaceutics' return on equity of 0.00% beat Aptevo Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
NLS PharmaceuticsN/A N/A N/A
Aptevo Therapeutics N/A -198.50%-117.06%

NLS Pharmaceutics has a beta of 0.94, suggesting that its stock price is 6% less volatile than the broader market. Comparatively, Aptevo Therapeutics has a beta of 1.65, suggesting that its stock price is 65% more volatile than the broader market.

Summary

NLS Pharmaceutics beats Aptevo Therapeutics on 6 of the 11 factors compared between the two stocks.

How does Aptevo Therapeutics compare to Quantum Biopharma?

Quantum Biopharma (NASDAQ:QNTM) and Aptevo Therapeutics (NASDAQ:APVO) are both small-cap healthcare companies, but which is the better business? We will compare the two companies based on the strength of their risk, analyst recommendations, institutional ownership, earnings, valuation, dividends, profitability and media sentiment.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Quantum Biopharma
1 Sell rating(s)
0 Hold rating(s)
0 Buy rating(s)
0 Strong Buy rating(s)
1.00
Aptevo Therapeutics
1 Sell rating(s)
1 Hold rating(s)
0 Buy rating(s)
1 Strong Buy rating(s)
2.33

In the previous week, Quantum Biopharma had 1 more articles in the media than Aptevo Therapeutics. MarketBeat recorded 2 mentions for Quantum Biopharma and 1 mentions for Aptevo Therapeutics. Quantum Biopharma's average media sentiment score of 1.05 beat Aptevo Therapeutics' score of 0.00 indicating that Quantum Biopharma is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Quantum Biopharma
2 Very Positive mention(s)
0 Positive mention(s)
0 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Aptevo Therapeutics
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Quantum Biopharma has a beta of 0.45, indicating that its share price is 55% less volatile than the broader market. Comparatively, Aptevo Therapeutics has a beta of 1.65, indicating that its share price is 65% more volatile than the broader market.

1.2% of Quantum Biopharma shares are held by institutional investors. Comparatively, 8.1% of Aptevo Therapeutics shares are held by institutional investors. 8.5% of Quantum Biopharma shares are held by company insiders. Comparatively, 0.5% of Aptevo Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth.

Aptevo Therapeutics' return on equity of -198.50% beat Quantum Biopharma's return on equity.

Company Net Margins Return on Equity Return on Assets
Quantum BiopharmaN/A -941.54% -224.41%
Aptevo Therapeutics N/A -198.50%-117.06%

Quantum Biopharma is trading at a lower price-to-earnings ratio than Aptevo Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Quantum BiopharmaN/AN/A-$26.17M-$8.25N/A
Aptevo TherapeuticsN/AN/A-$25.97M-$197.60N/A

Summary

Aptevo Therapeutics beats Quantum Biopharma on 8 of the 12 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding APVO and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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APVO vs. The Competition

MetricAptevo TherapeuticsBiotechnology IndustryHealthcare SectorNASDAQ Exchange
Market Cap$6.26M$3.71B$7.03B$12.96B
Dividend YieldN/A3.76%2.58%10.20%
P/E Ratio-0.029.06269.9124.87
Price / SalesN/A1,278.42654.69108.21
Price / CashN/A44.9528.8937.44
Price / Book0.2417.9711.406.45
Net Income-$25.97M-$13.25M$3.45B$347.50M
7 Day Performance4.28%5.58%3.66%3.77%
1 Month Performance4.54%-1.60%-0.49%-0.40%
1 Year Performance-89.87%61.32%77.51%23.55%

Aptevo Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
APVO
Aptevo Therapeutics
0.6102 of 5 stars
$4.12
-1.4%
N/A-89.7%$6.26MN/AN/A50
SKYE
Skye Bioscience
2.0453 of 5 stars
$0.57
-2.0%
$8.50
+1,395.2%
-85.2%$19.98MN/AN/A11
ALLR
Allarity Therapeutics
1.7241 of 5 stars
$1.21
-1.6%
$10.25
+747.1%
+43.3%$19.25M$320KN/A10
MRKR
Marker Therapeutics
1.6902 of 5 stars
$1.13
+0.9%
$10.00
+785.0%
-5.9%$18.84M$3.55MN/A60
NCEL
NLS Pharmaceutics
1.8284 of 5 stars
$3.49
+3.9%
$23.00
+559.0%
-84.5%$18.65MN/AN/A6

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This page (NASDAQ:APVO) was last updated on 8/10/2026 by MarketBeat.com Staff.
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