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Cardiol Therapeutics (CRDL) Competitors

Cardiol Therapeutics logo
$1.88 +0.02 (+0.81%)
Closing price 09/18/2026 04:00 PM Eastern
Extended Trading
$1.93 +0.05 (+2.72%)
As of 09/18/2026 07:30 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Massive. Learn more.

CRDL vs. ARDX, IVA, GLAS, GYRE, and COLL

Should you buy Cardiol Therapeutics stock or one of its competitors? Cardiol Therapeutics's main competitors and comparable companies include Ardelyx (ARDX), Inventiva (IVA), Glass House Brands (GLAS), Gyre Therapeutics (GYRE), and Collegium Pharmaceutical (COLL). Companies are selected based on similarities in market, industry, and size. These companies are all part of the "pharmaceuticals" industry.

How does Cardiol Therapeutics compare to Ardelyx?

Cardiol Therapeutics (NASDAQ:CRDL) and Ardelyx (NASDAQ:ARDX) are both small-cap healthcare companies, but which is the better stock? We will compare the two companies based on the strength of their risk, analyst recommendations, institutional ownership, media sentiment, valuation, dividends, earnings and profitability.

In the previous week, Ardelyx had 12 more articles in the media than Cardiol Therapeutics. MarketBeat recorded 15 mentions for Ardelyx and 3 mentions for Cardiol Therapeutics. Cardiol Therapeutics' average media sentiment score of 0.47 beat Ardelyx's score of 0.01 indicating that Cardiol Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Cardiol Therapeutics
0 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Ardelyx
1 Very Positive mention(s)
1 Positive mention(s)
9 Neutral mention(s)
3 Negative mention(s)
0 Very Negative mention(s)
Neutral

Cardiol Therapeutics has higher earnings, but lower revenue than Ardelyx. Ardelyx is trading at a lower price-to-earnings ratio than Cardiol Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Cardiol TherapeuticsN/AN/A-$24.20M-$0.25N/A
Ardelyx$407.32M2.09-$61.60M-$0.22N/A

Cardiol Therapeutics presently has a consensus price target of $10.00, suggesting a potential upside of 433.33%. Ardelyx has a consensus price target of $13.90, suggesting a potential upside of 306.43%. Given Cardiol Therapeutics' higher possible upside, analysts clearly believe Cardiol Therapeutics is more favorable than Ardelyx.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Cardiol Therapeutics
1 Sell rating(s)
0 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.50
Ardelyx
2 Sell rating(s)
0 Hold rating(s)
9 Buy rating(s)
1 Strong Buy rating(s)
2.75

Cardiol Therapeutics has a beta of 0.79, meaning that its stock price is 21% less volatile than the broader market. Comparatively, Ardelyx has a beta of 0.7, meaning that its stock price is 30% less volatile than the broader market.

Cardiol Therapeutics has a net margin of 0.00% compared to Ardelyx's net margin of -12.35%. Ardelyx's return on equity of -36.00% beat Cardiol Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Cardiol TherapeuticsN/A -180.44% -140.28%
Ardelyx -12.35%-36.00%-10.77%

12.5% of Cardiol Therapeutics shares are held by institutional investors. Comparatively, 58.9% of Ardelyx shares are held by institutional investors. 5.3% of Cardiol Therapeutics shares are held by insiders. Comparatively, 5.3% of Ardelyx shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.

Summary

Ardelyx beats Cardiol Therapeutics on 10 of the 16 factors compared between the two stocks.

How does Cardiol Therapeutics compare to Inventiva?

Inventiva (NASDAQ:IVA) and Cardiol Therapeutics (NASDAQ:CRDL) are both small-cap healthcare companies, but which is the better investment? We will contrast the two companies based on the strength of their institutional ownership, valuation, earnings, profitability, risk, analyst recommendations, dividends and media sentiment.

19.1% of Inventiva shares are held by institutional investors. Comparatively, 12.5% of Cardiol Therapeutics shares are held by institutional investors. 32.0% of Inventiva shares are held by company insiders. Comparatively, 5.3% of Cardiol Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock is poised for long-term growth.

In the previous week, Inventiva had 1 more articles in the media than Cardiol Therapeutics. MarketBeat recorded 4 mentions for Inventiva and 3 mentions for Cardiol Therapeutics. Cardiol Therapeutics' average media sentiment score of 0.47 beat Inventiva's score of 0.20 indicating that Cardiol Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Inventiva
0 Very Positive mention(s)
1 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Cardiol Therapeutics
0 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Inventiva presently has a consensus target price of $15.75, indicating a potential upside of 316.67%. Cardiol Therapeutics has a consensus target price of $10.00, indicating a potential upside of 433.33%. Given Cardiol Therapeutics' higher probable upside, analysts clearly believe Cardiol Therapeutics is more favorable than Inventiva.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Inventiva
1 Sell rating(s)
0 Hold rating(s)
7 Buy rating(s)
3 Strong Buy rating(s)
3.09
Cardiol Therapeutics
1 Sell rating(s)
0 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.50

Cardiol Therapeutics has lower revenue, but higher earnings than Inventiva.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Inventiva$5.07M154.86-$400.67MN/AN/A
Cardiol TherapeuticsN/AN/A-$24.20M-$0.25N/A

Inventiva's return on equity of 0.00% beat Cardiol Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
InventivaN/A N/A N/A
Cardiol Therapeutics N/A -180.44%-140.28%

Inventiva has a beta of 0.71, suggesting that its share price is 29% less volatile than the broader market. Comparatively, Cardiol Therapeutics has a beta of 0.79, suggesting that its share price is 21% less volatile than the broader market.

Summary

Inventiva beats Cardiol Therapeutics on 9 of the 13 factors compared between the two stocks.

How does Cardiol Therapeutics compare to Glass House Brands?

Cardiol Therapeutics (NASDAQ:CRDL) and Glass House Brands (NYSE:GLAS) are both small-cap healthcare companies, but which is the superior investment? We will compare the two businesses based on the strength of their profitability, risk, earnings, analyst recommendations, valuation, dividends, media sentiment and institutional ownership.

In the previous week, Glass House Brands had 1 more articles in the media than Cardiol Therapeutics. MarketBeat recorded 4 mentions for Glass House Brands and 3 mentions for Cardiol Therapeutics. Glass House Brands' average media sentiment score of 1.10 beat Cardiol Therapeutics' score of 0.47 indicating that Glass House Brands is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Cardiol Therapeutics
0 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Glass House Brands
2 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Cardiol TherapeuticsN/AN/A-$24.20M-$0.25N/A
Glass House BrandsN/AN/AN/AN/AN/A

12.5% of Cardiol Therapeutics shares are held by institutional investors. 5.3% of Cardiol Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Glass House Brands' return on equity of 0.00% beat Cardiol Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Cardiol TherapeuticsN/A -180.44% -140.28%
Glass House Brands N/A N/A N/A

Cardiol Therapeutics presently has a consensus target price of $10.00, indicating a potential upside of 433.33%. Glass House Brands has a consensus target price of $16.00, indicating a potential upside of 102.92%. Given Cardiol Therapeutics' stronger consensus rating and higher possible upside, equities analysts clearly believe Cardiol Therapeutics is more favorable than Glass House Brands.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Cardiol Therapeutics
1 Sell rating(s)
0 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.50
Glass House Brands
1 Sell rating(s)
1 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
2.00

Summary

Cardiol Therapeutics beats Glass House Brands on 5 of the 9 factors compared between the two stocks.

How does Cardiol Therapeutics compare to Gyre Therapeutics?

Cardiol Therapeutics (NASDAQ:CRDL) and Gyre Therapeutics (NASDAQ:GYRE) are both small-cap healthcare companies, but which is the better business? We will contrast the two companies based on the strength of their institutional ownership, analyst recommendations, media sentiment, profitability, valuation, earnings, risk and dividends.

In the previous week, Cardiol Therapeutics had 3 more articles in the media than Gyre Therapeutics. MarketBeat recorded 3 mentions for Cardiol Therapeutics and 0 mentions for Gyre Therapeutics. Cardiol Therapeutics' average media sentiment score of 0.47 beat Gyre Therapeutics' score of 0.00 indicating that Cardiol Therapeutics is being referred to more favorably in the media.

Company Overall Sentiment
Cardiol Therapeutics Neutral
Gyre Therapeutics Neutral

Cardiol Therapeutics has a beta of 0.79, meaning that its share price is 21% less volatile than the broader market. Comparatively, Gyre Therapeutics has a beta of 1.92, meaning that its share price is 92% more volatile than the broader market.

12.5% of Cardiol Therapeutics shares are held by institutional investors. Comparatively, 24.0% of Gyre Therapeutics shares are held by institutional investors. 5.3% of Cardiol Therapeutics shares are held by insiders. Comparatively, 9.5% of Gyre Therapeutics shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.

Gyre Therapeutics has higher revenue and earnings than Cardiol Therapeutics. Gyre Therapeutics is trading at a lower price-to-earnings ratio than Cardiol Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Cardiol TherapeuticsN/AN/A-$24.20M-$0.25N/A
Gyre Therapeutics$116.59M7.22$5.03M-$0.21N/A

Cardiol Therapeutics currently has a consensus price target of $10.00, suggesting a potential upside of 433.33%. Gyre Therapeutics has a consensus price target of $16.00, suggesting a potential upside of 111.92%. Given Cardiol Therapeutics' stronger consensus rating and higher possible upside, equities analysts clearly believe Cardiol Therapeutics is more favorable than Gyre Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Cardiol Therapeutics
1 Sell rating(s)
0 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.50
Gyre Therapeutics
2 Sell rating(s)
0 Hold rating(s)
1 Buy rating(s)
0 Strong Buy rating(s)
1.67

Cardiol Therapeutics has a net margin of 0.00% compared to Gyre Therapeutics' net margin of -15.47%. Gyre Therapeutics' return on equity of -6.57% beat Cardiol Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Cardiol TherapeuticsN/A -180.44% -140.28%
Gyre Therapeutics -15.47%-6.57%-5.35%

Summary

Gyre Therapeutics beats Cardiol Therapeutics on 8 of the 15 factors compared between the two stocks.

How does Cardiol Therapeutics compare to Collegium Pharmaceutical?

Cardiol Therapeutics (NASDAQ:CRDL) and Collegium Pharmaceutical (NASDAQ:COLL) are both small-cap healthcare companies, but which is the better business? We will compare the two companies based on the strength of their valuation, earnings, dividends, analyst recommendations, risk, profitability, media sentiment and institutional ownership.

12.5% of Cardiol Therapeutics shares are owned by institutional investors. 5.3% of Cardiol Therapeutics shares are owned by company insiders. Comparatively, 1.9% of Collegium Pharmaceutical shares are owned by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Cardiol Therapeutics has a beta of 0.79, meaning that its share price is 21% less volatile than the broader market. Comparatively, Collegium Pharmaceutical has a beta of 0.72, meaning that its share price is 28% less volatile than the broader market.

Collegium Pharmaceutical has a net margin of 5.93% compared to Cardiol Therapeutics' net margin of 0.00%. Collegium Pharmaceutical's return on equity of 91.43% beat Cardiol Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Cardiol TherapeuticsN/A -180.44% -140.28%
Collegium Pharmaceutical 5.93%91.43%15.57%

In the previous week, Collegium Pharmaceutical had 1 more articles in the media than Cardiol Therapeutics. MarketBeat recorded 4 mentions for Collegium Pharmaceutical and 3 mentions for Cardiol Therapeutics. Cardiol Therapeutics' average media sentiment score of 0.47 beat Collegium Pharmaceutical's score of -0.31 indicating that Cardiol Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Cardiol Therapeutics
0 Very Positive mention(s)
1 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral
Collegium Pharmaceutical
1 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
2 Negative mention(s)
0 Very Negative mention(s)
Neutral

Cardiol Therapeutics currently has a consensus target price of $10.00, indicating a potential upside of 433.33%. Collegium Pharmaceutical has a consensus target price of $48.50, indicating a potential upside of 113.00%. Given Cardiol Therapeutics' higher probable upside, research analysts plainly believe Cardiol Therapeutics is more favorable than Collegium Pharmaceutical.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Cardiol Therapeutics
1 Sell rating(s)
0 Hold rating(s)
3 Buy rating(s)
0 Strong Buy rating(s)
2.50
Collegium Pharmaceutical
1 Sell rating(s)
2 Hold rating(s)
5 Buy rating(s)
0 Strong Buy rating(s)
2.50

Collegium Pharmaceutical has higher revenue and earnings than Cardiol Therapeutics. Cardiol Therapeutics is trading at a lower price-to-earnings ratio than Collegium Pharmaceutical, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Cardiol TherapeuticsN/AN/A-$24.20M-$0.25N/A
Collegium Pharmaceutical$780.57M0.95$62.87M$1.2418.36

Summary

Collegium Pharmaceutical beats Cardiol Therapeutics on 9 of the 14 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding CRDL and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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CRDL vs. The Competition

MetricCardiol TherapeuticsPharmaceuticals IndustryHealthcare SectorNASDAQ Exchange
Market Cap$217.83M$12.47B$7.24B$13.19B
Dividend YieldN/A2.64%2.57%12.81%
P/E Ratio-7.50792.21274.9325.38
Price / SalesN/A753.62646.0189.45
Price / CashN/A86.3676.2551.42
Price / Book17.0510.5310.466.33
Net Income-$24.20M$2.82B$3.49B$358.33M
7 Day Performance-6.02%1.69%0.59%1.12%
1 Month Performance-4.34%0.83%-2.01%-2.67%
1 Year Performance67.41%3.90%18.09%6.01%

Cardiol Therapeutics Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
CRDL
Cardiol Therapeutics
2.656 of 5 stars
$1.88
+0.8%
$10.00
+433.3%
+68.9%$217.83MN/AN/A18
ARDX
Ardelyx
3.0265 of 5 stars
$3.40
-3.6%
$13.90
+309.4%
-46.7%$846M$407.32MN/A489
IVA
Inventiva
2.5812 of 5 stars
$3.84
-1.2%
$15.38
+300.9%
-30.3%$798.84M$4.48MN/A73
GLAS
Glass House Brands
3.6136 of 5 stars
$8.17
+0.9%
$16.00
+95.8%
N/A$765.88MN/AN/A357
GYRE
Gyre Therapeutics
1.7718 of 5 stars
$6.51
-2.8%
$16.00
+146.0%
-1.8%$731.06M$116.59MN/A618

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This page (NASDAQ:CRDL) was last updated on 9/19/2026 by MarketBeat.com Staff.
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