Harmony Biosciences (HRMY) Competitors $26.63 -0.21 (-0.78%) Closing price 04:00 PM EasternExtended Trading$26.64 +0.01 (+0.02%) As of 04:53 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock HRMY vs. AXSM, LEGN, PCVX, MTSR, PTGX, TGTX, PTCT, KRYS, ARWR, and ACLXShould you be buying Harmony Biosciences stock or one of its competitors? The main competitors of Harmony Biosciences include Axsome Therapeutics (AXSM), Legend Biotech (LEGN), Vaxcyte (PCVX), Metsera (MTSR), Protagonist Therapeutics (PTGX), TG Therapeutics (TGTX), PTC Therapeutics (PTCT), Krystal Biotech (KRYS), Arrowhead Pharmaceuticals (ARWR), and Arcellx (ACLX). These companies are all part of the "pharmaceutical products" industry. Harmony Biosciences vs. Its Competitors Axsome Therapeutics Legend Biotech Vaxcyte Metsera Protagonist Therapeutics TG Therapeutics PTC Therapeutics Krystal Biotech Arrowhead Pharmaceuticals Arcellx Harmony Biosciences (NASDAQ:HRMY) and Axsome Therapeutics (NASDAQ:AXSM) are both medical companies, but which is the superior investment? We will contrast the two businesses based on the strength of their risk, institutional ownership, analyst recommendations, media sentiment, earnings, profitability, valuation and dividends. Is HRMY or AXSM more profitable? Harmony Biosciences has a net margin of 23.44% compared to Axsome Therapeutics' net margin of -49.88%. Harmony Biosciences' return on equity of 26.34% beat Axsome Therapeutics' return on equity.Company Net Margins Return on Equity Return on Assets Harmony Biosciences23.44% 26.34% 17.71% Axsome Therapeutics -49.88%-283.22%-33.06% Do analysts recommend HRMY or AXSM? Harmony Biosciences presently has a consensus target price of $45.56, suggesting a potential upside of 71.07%. Axsome Therapeutics has a consensus target price of $177.93, suggesting a potential upside of 37.32%. Given Harmony Biosciences' higher probable upside, equities analysts clearly believe Harmony Biosciences is more favorable than Axsome Therapeutics.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Harmony Biosciences 0 Sell rating(s) 2 Hold rating(s) 7 Buy rating(s) 1 Strong Buy rating(s) 2.90Axsome Therapeutics 1 Sell rating(s) 0 Hold rating(s) 14 Buy rating(s) 2 Strong Buy rating(s) 3.00 Do institutionals & insiders believe in HRMY or AXSM? 86.2% of Harmony Biosciences shares are held by institutional investors. Comparatively, 81.5% of Axsome Therapeutics shares are held by institutional investors. 23.6% of Harmony Biosciences shares are held by company insiders. Comparatively, 22.4% of Axsome Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a company is poised for long-term growth. Which has more risk & volatility, HRMY or AXSM? Harmony Biosciences has a beta of 0.79, suggesting that its stock price is 21% less volatile than the S&P 500. Comparatively, Axsome Therapeutics has a beta of 0.52, suggesting that its stock price is 48% less volatile than the S&P 500. Which has stronger valuation and earnings, HRMY or AXSM? Harmony Biosciences has higher revenue and earnings than Axsome Therapeutics. Axsome Therapeutics is trading at a lower price-to-earnings ratio than Harmony Biosciences, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioHarmony Biosciences$714.73M2.14$145.49M$3.108.59Axsome Therapeutics$385.69M16.76-$287.22M-$5.07-25.56 Does the media refer more to HRMY or AXSM? In the previous week, Axsome Therapeutics had 31 more articles in the media than Harmony Biosciences. MarketBeat recorded 38 mentions for Axsome Therapeutics and 7 mentions for Harmony Biosciences. Harmony Biosciences' average media sentiment score of 0.98 beat Axsome Therapeutics' score of 0.45 indicating that Harmony Biosciences is being referred to more favorably in the media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Harmony Biosciences 3 Very Positive mention(s) 0 Positive mention(s) 0 Neutral mention(s) 2 Negative mention(s) 0 Very Negative mention(s) Positive Axsome Therapeutics 12 Very Positive mention(s) 3 Positive mention(s) 3 Neutral mention(s) 1 Negative mention(s) 1 Very Negative mention(s) Neutral SummaryHarmony Biosciences beats Axsome Therapeutics on 12 of the 17 factors compared between the two stocks. Get Harmony Biosciences News Delivered to You Automatically Sign up to receive the latest news and ratings for HRMY and its competitors with MarketBeat's FREE daily newsletter. Subscribe Now View SMS TermsBy entering your phone number and clicking the sign-up button, you agree to receive periodic text messages from MarketBeat at the phone number you submitted, including texts that may be sent using an automatic telephone dialing system. Message and data rates may apply. Message frequency will vary. Messages will consist of stock alerts, news stories, and partner advertisements/offers. Consent is not a condition of the purchase of any goods or services. Text HELP for help/customer support. Unsubscribe at any time by replying "STOP" to any text message that you receive from MarketBeat or by visiting our mailing preferences page. Read our full terms of service and privacy policy. New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding HRMY and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart HRMY vs. The Competition Export to ExcelMetricHarmony BiosciencesMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$1.53B$3.39B$6.04B$10.49BDividend YieldN/A2.30%5.73%4.80%P/E Ratio8.5922.9085.1927.32Price / Sales2.14269.18516.16194.55Price / Cash8.9546.9537.5761.53Price / Book2.3010.5312.426.81Net Income$145.49M-$52.58M$3.32B$276.59M7 Day Performance0.26%1.06%0.80%0.15%1 Month Performance-18.06%16.05%10.52%8.17%1 Year Performance-24.99%18.41%76.14%35.50% Harmony Biosciences Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)HRMYHarmony Biosciences4.7039 of 5 stars$26.63-0.8%$45.56+71.1%-24.4%$1.53B$714.73M8.59200Analyst ForecastAXSMAxsome Therapeutics4.688 of 5 stars$121.15-0.5%$177.93+46.9%+44.6%$6.07B$385.69M-23.90380Analyst RevisionLEGNLegend Biotech2.6379 of 5 stars$32.85+3.6%$69.25+110.8%-33.1%$5.85B$627.24M-37.332,609News CoverageHigh Trading VolumePCVXVaxcyte2.1266 of 5 stars$43.81+0.3%$106.25+142.5%-62.1%$5.67BN/A-10.66160Analyst ForecastMTSRMetseraN/A$52.97+0.2%$55.75+5.2%N/A$5.55BN/A0.0081PTGXProtagonist Therapeutics1.6812 of 5 stars$79.17-9.0%$72.00-9.1%+66.0%$5.41B$434.43M113.10120Analyst ForecastInsider TradeGap DownHigh Trading VolumeTGTXTG Therapeutics4.4231 of 5 stars$34.22+1.4%$49.00+43.2%+49.5%$5.36B$329M92.49290Positive NewsPTCTPTC Therapeutics3.2356 of 5 stars$66.06-0.3%$69.00+4.5%+68.9%$5.26B$806.78M9.481,410Analyst RevisionKRYSKrystal Biotech4.355 of 5 stars$184.74+1.8%$209.00+13.1%+4.7%$5.25B$290.52M37.55210News CoverageAnalyst RevisionARWRArrowhead Pharmaceuticals3.8861 of 5 stars$36.25+2.4%$43.14+19.0%+85.7%$4.90B$3.55M-28.32400ACLXArcellx2.0028 of 5 stars$86.23-0.7%$112.69+30.7%+0.6%$4.81B$107.94M-25.2180Analyst Revision Related Companies and Tools Related Companies Axsome Therapeutics Alternatives Legend Biotech Alternatives Vaxcyte Alternatives Metsera Alternatives Protagonist Therapeutics Alternatives TG Therapeutics Alternatives PTC Therapeutics Alternatives Krystal Biotech Alternatives Arrowhead Pharmaceuticals Alternatives Arcellx Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:HRMY) was last updated on 10/15/2025 by MarketBeat.com Staff From Our PartnersURGENT: The Market's 3 Red Flags Are FlashingHere’s the uncomfortable truth: The smartest investors in the world are already preparing for a crash befor...StockEarnings | SponsoredYour Bank Account Is No Longer SafeWhat If Washington Declared That: YOUR Money ISN'T Actually Yours? 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